Post-traumatic stress disorder (PTSD) is a trauma-induced psychiatric disorder characterized by impaired fear extermination, hyperarousal, anxiety, depression, and amnesic symptoms that may involve the release of monoamines in the fear circuit. The present study measured several anxiety-related behavioral responses to examine the effects of berberine (BER) on symptoms of anxiety in rats after single prolonged stress (SPS) exposure, and to determine if BER reversed the dopamine (DA) dysfunction. Rats received BER (10, 20, or 30 mg/kg, intraperitoneally, once daily) for 14 days after SPS exposure. BER administration significantly increased the time spent in the open arms and reduced grooming behavior during the elevated plus maze test, and increased the time spent in the central zone and the number of central zone crossings in the open field test. BER restored neurochemical abnormalities and the SPS-induced decrease in DA tissue levels in the hippocampus and striatum. The increased DA concentration during BER treatment may partly be attributed to mRNA expression of tyrosine hydroxylase and the DA transporter in the hippocampus, while BER exerted no significant effects on vesicular monoamine transporter mRNA expression in the hippocampus of rats with PTSD. These results suggest that BER had anxiolytic-like effects on behavioral and biochemical measures associated with anxiety. These findings support a role for reduced anxiety altered DAergic transmission and reduced anxiety in rats with PTSD. Thus, BER may be a useful agent to treat or alleviate psychiatric disorders like those observed in patients with PTSD.
Kim, Il-Ho;Noh, Samuel;Choi, Cyu-Chul;McKenzie, Kwame
Journal of Preventive Medicine and Public Health
/
제52권5호
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pp.299-307
/
2019
Objectives: While occupational stress has long been a central focus of psychological research, few studies have investigated how immigrant microbusiness owners (MBOs) respond to their unusually demanding occupation, or how their unresolved occupational stress manifests in psychological distress. Based on the job demands-resources model, this study compared MBOs to employees with regard to the relationships among emotional demands, job resources, and depressive symptoms. Methods: Data were derived from a cross-sectional survey of 1288 Korean immigrant workers (MBOs, professionals, office workers, and manual workers) aged 30 to 70, living in Toronto and surrounding areas. Face-to-face interviews were conducted between March 2013 and November 2013. Results: Among the four occupational groups, MBOs appeared to endure the greatest level of emotional demands, while reporting relatively lower levels of job satisfaction and job security; but MBOs reported the greatest job autonomy. The effect of emotional demands on depressive symptoms was greater for MBOs than for professionals. However, an inspection of stress-resource interactions indicated that though MBOs enjoyed the greatest autonomy, the protective effects of job satisfaction and security on the psychological risk of emotional demands appeared to be more pronounced for MBOs than for any of the employee groups. Conclusions: One in two Korean immigrants choose self-employment, most typically in family-owned microbusinesses that involve emotionally taxing dealings with clients and suppliers. However, the benefits of job satisfaction and security may protect MBOs from the adverse mental health effects of job stress.
Objective : This study compared the psychological stresses of depressed patients' families with those of schizophrenic patients' families. We investigated the influence of depressive patients' clinical features and their families' demographic characteristics on the families' depressive symptoms and stresses. Methods : Participants were 23 family members of depressed patients and 20 family members of schizophrenic patients. We measured the patients' clinical features (duration of illness, number of previous hospitalizations, and satisfaction with medication), and each family member's socioeconomic status and psychological characteristics (depressive mood, anxiety, family stress, and stress response), analyzing the data via independent t-test, chi-square test, and correlation and hierarchical multiple regression analyses. Results : The depressed patients' average clinical global impression (CGI) was significantly higher than that of the schizophrenic patients. The depressed patients' family members showed stress responses significantly higher than those of schizophrenic patients' family members. Furthermore, in depressed patients, frequency of hospitalization was positively correlated with family members' stat anxiety. For both patient types, family stress was positively correlated with the patient's severity of illness and the family's state anxiety, trait anxiety, and stress response ; socioeconomic status was positively correlated with the family's depressive symptoms ; the family's state anxiety positively correlated with the family's trait anxiety and stress response ; and the family's trait anxiety positively correlated with the family's stress response. Socioeconomic status predicted the family's depressive symptoms, and socioeconomic, illness severity and stress response predicted family stress. Conclusion : These findings suggest that both depressed patients' families and schizophrenic patients' families suffer from psychological stress. The study data also have important clinical implications, in that families of depressed patients need psychiatric intervention, as well as the patients themselves. In particular, family intervention should focus on psycho-education and stress coping strategies.
The psychosocial stress and musculoskeletal disorders(MSDs) have been one of major health problems for hospital workers. This study tried to understand the relationship between symptoms associated with MSDs and risk factors such as working posture, job stress, psychosocial stress and fatigue. A total number of 655 hospital workers participated in this study. Specifically, REBA was applied for evaluating working posture and a checklist prepared by KOSHA(Korean Occupational Safety and Health Agency) was used for symptom survey. A questionnaire from KOSHA was also used for collecting data associated with job stress, psychosocial stress and fatigue. All these data were formulated and modeled by path analysis which was one of major statistical tools in this study. Specifically, path analysis for the data we collected came up with several major findings. As a result, as for body part(neck), (waist) and (arms) the degree of risk of work posture measured with the use of job stress(KOSS), psycho-social stress(PWI-SF) and REBA is significantly more affected by fatigue than muscular skeletal disease related consciousness symptom. However, regarding bod(wrist), the degree of risk of work posture measured with the use of job stress(KOSS) and REBA is directly affected by muscular skeletal disease related consciousness symptom. This study is meaningful in that the study clarified the causal relations of the degree of risk of work posture, degree of fatigue, and muscular skeletal disease related consciousness symptoms by each body part measured with the use of work stress(KOSS), psycho-social stress(PWI-SF) and REBA.
Background: This study aims to analyze the job stress of dental hygienists and the factors affecting somatization and to provide basic data for effectively managing job stress and somatization of dental hygienists. Methods: In this study, the data collected from 208 dental hygienists working in Jeollabuk-do Province were analyzed. Job stress was investigated using a questionnaire with 43 questions. In addition, the degree of somatization was evaluated through a simplified psychotherapy examination (Symptom Check List-90-Revision). Results: Age, employment history, position, average monthly income, night duty execution status, and perceived health status were significantly associated with job stress (p<0.05). The job stress sub-items scores based on general characteristics showed significance in 'workload' for those working a five-day workweek and perceived health status (p<0.05). Age, average monthly income, and perceived health status were noted in 'role conflict as a professional'. In 'lack of expertise and skill', it was noted that age, employment history, position, income, and night clinic were implemented. In 'improper treatment and interpersonal issues', level of education and perceived health status were significant (p<0.05). The higher the job stress, the higher the somatization symptom score (p<0.05), and the higher the job stress component, the higher the somatization symptom score (p<0.01). Conclusion: The job stress of dental hygienists should be reduced, and the symptoms of somatization should be mitigated. To improve the quality of medical services and the work efficiency of dental hygienists, proper treatment and compensation systems should be implemented for them to take pride as professional. Further, programs and regulations on mitigating job stress and somatization symptoms should be developed.
본 연구는 스트레스와 생리 변인(면역, 염증)을 검증하기 이전, 스트레스 대처와 대처방법을 연령대별 우울, 불안 증세를 분석하여 기초 자료 제공을 위한 pilot test를 실시하였다. 비대면 방법으로 BDI 및 STAI를 연령대별(20대~70대) 비대면조사와 대면조사를 병행, 추적조사로 실시하였다. 20대부터 60대에서 대처방법에 따라 스트레스 해소 후 유의한 저하를 보였고, 불안은 모든 연령대에서 스트레스 해소 후 유의한 저하를 보였으며, 50대는 운동에 의한 스트레스 대처가 스트레스 해소 후 제일 낮게 나타났다. 본 연구의 결과를 바탕으로 심리 변인에 따른 기초 연구를 통해 실제 스트레스 대처방법에 따른 생리적 변인을 추가 검증하여 높은 스트레스 수준을 보이는 대상을 모집단으로 장기간의 운동 처치를 통해 운동요법에 의해서 우울 및 불안증세 개선과 면역, 염증 반응과의 상관관계 등을 연령대별, 대상별 적합한 스트레스 대처방법을 추가적으로 검증해야 할 것이다.
This study was designed and carried out to investigate the effect of Assertiveness Training on the stress response and assertive behavior of emergency room nurses from September 22, to December 21. 1997. The subjects were 45 emergency room nurses of three general hospitals of Korea University Medical Center; 25 assigned for the experimental and 20 for the control group. The Assertive Training Program was composed of cognitive training, behavioral training and progressive muscle relaxation. The subjects of the experimental group carried out the 15-minute progressive muscle relaxation according to recorded-tape once a day for 6 weeks. The cognitive and the behavioural training were conducted by the investigator for 5-8 subjects at a time for 9 series, at an interval of 4-5 days. Post-measurement were administered to all sujects in two groups three weeks after the last session. The level of general stress (Cline, 1992), job stress (Kim & Koo, 1984), physiological response to stress (cortisol, epinephrine, norepinephrine), symptoms of stress (Lee, 1984) and assertive behavior (Kim, 1982) were measured before the first and after the last experiments. Data were analysed by x2, t, paired t, Wilcoxon signed rank tests Wilcoxon rank sums tests. The results are as follows : 1. The level of general stress of the experimental group was lower than that of the control group, however, no significant difference between the two groups (P=0.234) was revealed. 2. A significant reduction of job stress was revealed in the experimental group (P=0.017). 1) A significant reduction of interpersonal conflicts in the experimental group was revealed (P=0.018). 3. The physiological stress-response were analyzed as follows : 1) A decrease of Cortisol in both the experimental and the control groups was noticed, however, the difference between the two groups was not statistically significant (P=0.991). Pre-and post-measurement of the level of Corti sol revealed that a notable decrease in the experimental group and an increase in the control group with no significant difference in the day-day subjects (P=0.765), a significant decrease was noted on the level of Cortisol of the experimental group in the night-night nurses (P=0.036). 2) An increase of Epinephrine in both groups was noticed, however, a difference was not statistically significant between the two groups (P=0.082). Pre-and post-measurement of the level of Epinephrine revealed that a notable decrease in the experimental group and an increase in the control group with no significant difference in the day-day subjects (P=0.136). increases were noted on the level of Epinephrinel of both groups in the night-night nurses (P=0.136), 3) The level of Norepinephrine of the experimental group was significantly decreased (P=0.020). Pre-and post-measurement of the level of Norepinephrine revealed that a notable decrease in the experimental group and an increase in the control group with no significant difference in the day-day subjects (P=0.073). a significant decrease was noted on the level of Norepinephrine of the experimental group in the night-night nurses (P=0.036), 4. Symptoms of stress were reduced in both groups, with no significant differences between the groups (P=0.127). 1) The physical stress symptoms were reduced in both groups, with no significant difference (P=0.386), 2) The cognitive-behavioral stress symptoms were significantly reduced in the experimental group (P=0.037). 3) The emotional stress symptoms were reduced in both groups with no significant difference between the groups (P=0.110). 5. The assertive behavior was significantly increased in the experimental group (P=0.000). This study signified the Assertiveness Training as an effective mean of self intervention for the reduction of stress of nurses assigned to emergency rooms.
Purpose: The purpose of this study was to identify the effects of pelvic floor muscle exercise on reducing the symptoms of stress urinary incontinence and improving attitude toward exercise and quality of life. Method: The research adopted was a nonequivalent control group pretest posttest design. The subjects were 55 persons who were surveyed using a structured questionnaire, and 23 persons in the experimental group among the total sample were measured for the peak pressure and the duration of PMC and trained correct pelvic floor muscle contraction using peritron in the first week. Then, pelvic floor muscle exercise was implemented for 6 weeks. The data was analyzed by $\chi^2$-test and t-test with the SPSS 10.0 program. Results: 1) The degree of stress urinary incontinence, frequency of urination, nocturia, urgency, noctural incontinence, the frequency and quantity of incontinence, outer clothing change and incomplete emptying decreased significantly more in the experimental group than in the control group. 2) Attitude toward pelvic floor muscle exercise and the qualify of life were improved significantly more in the experimental group than in the control group. 3) The peak pressure and duration of PMC increased significantly more in the posttest. Conclusion: Based on the results above, it is judged that pelvic floor muscle exercise is an effective nursing intervention in order to care for stress urinary incontinence.
Purpose: This study aimed to develop and examine the effects of a psychosocial adaptation program for North Korean adolescent defectors. Methods: This quasi-experimental study was conducted with 28 North Korean adolescent defectors who were recruited through alternative schools. The experimental and control groups consisted of 14 participants each. A program was conducted across eight sessions, each lasting about 90-120 minutes. The data were analyzed using the x2 test, t-test, paired t-test, and analysis of covariance. Results: No significant differences were observed in the score changes for psychosocial adaptation (t=0.25, p=.808), post-traumatic stress symptoms (t=0.32, p=.749), cultural adaptation stress (t=0.05, p=.957), and self-efficacy (t=0.35, p=.726) in either group before and after the intervention. No intergroup differences were observed for psychosocial adaptation (t=0.12, p=.902), post-traumatic stress symptoms (t=0.07, p=.946), cultural adaptation stress (t=0.01, p=.994), and self-efficacy (t=0.58, p=.570). Conclusion: These findings suggest that psychosocial adaptation, stress, and self-efficacy cannot be improved by a short-term intervention program alone. It was also determined that the cultural characteristics of the North Korean adolescent defectors were not sufficiently considered before implementing the program. Therefore, it is essential to provide an in-depth orientation for the participants before implementing the program.
Purpose: The reproductive health of women in early adulthood can affect pregnancy, childbirth, and menopause in later life. Menstrual symptoms not only affect daily life, but are also a reflection of a woman's reproductive health. This study was conducted to explore the factors affecting menstrual symptoms among university students. Methods: The general characteristics, life style, menstrual characteristics, stress, and menstrual symptom of 177 female students were assessed through an online survey at one university. An independent sample t-test, one-way variance analysis, correlation analysis, and multiple regression analysis were performed using the SPSS 22.0 program. Results: The menstrual symptom score was 91.68±32.11 points, and the score of 'mood change' was the highest. Stress (=.38, p<.001), amount of menstruation (=.20, p=.001), menarche age (=-.18, p=.003), health problems (=.16, p=.010), and age (=.15, p=.016) were found to have a significant effect on menstrual symptom, and the explanatory power of the regression model was 40%. Conclusion: This study investigated the degree and influencing factors of menstrual symptom using the Korean Menstrual Symptom Scale (KMSS) developed for Korean university students. Among the factors influencing menstrual symptom, stress appeared to play a significant role. Stress management, observation of menstrual characteristics, and general health care are necessary to maintain a woman's reproductive health.
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