• Title/Summary/Keyword: Stress reaction

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Effects of 630-nm Organic Light-emitting Diodes on Antioxidant Regulation and Aging-related Gene Expression Compared to Light-emitting Diodes of the Same Wavelength

  • Mo, SangJoon;Kim, Eun Young;Ahn, Jin Chul
    • Current Optics and Photonics
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    • v.6 no.3
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    • pp.227-235
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    • 2022
  • To investigate the aging-related physiological functions of organic light-emitting diodes (OLEDs), we examined mRNA expression changes in aging-related genes due to oxidative stress inhibition by 630-nm red light OLEDs. As a result of irradiating 630-nm OLED with an intensity of 5 mW/cm2 for 15 min, the viability of dermal fibroblasts significantly increased by 1.3-fold. In addition, reactive oxygen species generated by H2O2 were significantly reduced about 4.9-fold by irradiation with 630-nm OLED. Quantitative reverse-transcription polymerase chain reaction results showed that 630-nm OLEDs altered aging-related gene mRNA expression levels through antioxidant activity. The mRNA expression levels of matrix metalloproteinase1 (MMP1) and MMP9 decreased significantly, by about 2.2- and 2.5-fold, compared to the control group, whereas those of collagen, type I, and alpha 1 increased significantly, by 4.9-fold. The mRNA expression levels of cancer suppression genes p16 and p53 in dermal fibroblasts were also significantly reduced by 630-nm OLED irradiation, by about 1.4- and three-fold, respectively, compared to the control. Overall, it was confirmed that 630-nm OLED irradiation lowered the level of ROS formation induced by H2O2 in dermal fibroblasts, and that this antioxidant effect could regulate the mRNA expression levels of aging- and tumor suppression-related genes. This study shows a link between 630-nm OLED irradiation and anti-aging physiological functions such as antioxidant function, and suggests the potential of OLEDs as a useful light source for skin care.

The Research for Skin Condition Related with Physiological Phenomenon (여성의 생리적인 현상에 따른 피부상태와의 상관성 관련 요인에 관한 연구)

  • Lee, Jun-Cheol
    • The Journal of the Convergence on Culture Technology
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    • v.7 no.2
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    • pp.207-216
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    • 2021
  • This study was conducted on 315 women in their 20s and 40s living in Changwon, South Gyeongsang Province, and recorded in a self-recorded format using the questionnaire survey method. In this study, the skin type according to the skin condition was not applied for 30 minutes after washing and checking the cheek area through the examination method to distinguish it by intelligence, neutral, dryness and boredom to see the interaction with each condition. The X2-test was conducted to find out the relevance between each factor and the data processing was done using PC/SAS. We reached at following conclusions. We can find some connections between skin condition and age, job, marriage by statistics(p<0.01). Each value of X2-TEST was 42.961(p<0.001) and 7.345(p<0.05). The pimples are shown after stress on cheek, chin and around neck easily. We also find some connections between skin trouble reaction and the beginning of pimple shown time(p<0.01).

Effect of Hydrogen Concentration on Surface Oxidation Behavior of Alloy 600 in Simulated Primary Water of Pressurized Water Reactor (원전 1차측 수화학 환경에서 수소 농도가 Alloy 600의 표면산화 거동에 미치는 영향)

  • Yun Soo, Lim;Dong Jin, Kim;Sung Woo, Kim;Seong Sik, Hwang;Hong Pyo, Kim;Sung Hwan, Cho
    • Corrosion Science and Technology
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    • v.21 no.6
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    • pp.466-475
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    • 2022
  • Surface oxides and intergranular (IG) oxidation phenomena in Alloy 600 depending on hydrogen concentration were characterized to obtain clear insight into the primary water stress corrosion cracking (PWSCC) behavior upon exposure to pressurized water reactor primary water. When hydrogen concentration was between 5 and 30 cm3 H2/kg H2O, NiFe2O4 and NiO type oxides were found on the surface. NiO type oxides were found inside the oxidized grain boundary when hydrogen concentration was 5 cm3 H2/kg H2O. However, only NiFe2O4 spinel on the surface and Ni enrichment were observed when hydrogen concentration was 30 cm3 H2/kg H2O. These results indicate that the oxidation/reduction reaction of Ni in Alloy 600 depending on hydrogen concentration can considerably affect surface oxidation behavior. It appears that the formation of NiO type oxides in a Ni oxidation state and Ni enrichment in a Ni reduction (or metallic) state are common in primary water. It is believed that the above different oxidation/reduction reactions of Ni in Alloy 600 depending on hydrogen concentration can also significantly affect the resistance to PWSCC of Alloy 600.

Stabilization of High Nickel Cathode Materials with Core-Shell Structure via Co-precipitation Method (공침법을 통하여 합성된 코어-쉘 구조를 가지는 하이 니켈 양극 소재 안정화)

  • Kim, Minjeong;Hong, Soonhyun;Jeon, Heongkwon;Koo, Jahun;Lee, Heesang;Choi, Gyuseok;Kim, Chunjoong
    • Korean Journal of Materials Research
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    • v.32 no.4
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    • pp.216-222
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    • 2022
  • The capacity of high nickel Li(NixCoyMn1-x-y)O2 (NCM, x ≥ 0.8) cathodes is known to rapidly decline, a serious problem that needs to be solved in a timely manner. It was reported that cathode materials with the {010} plane exposed toward the outside, i.e., a radial structure, can provide facile Li+ diffusion paths and stress buffer during repeated cycles. In addition, cathodes with a core-shell composition gradient are of great interest. For example, a stable surface structure can be achieved using relatively low nickel content on the surface. In this study, precursors of the high-nickel NCM were synthesized by coprecipitation in ambient atmosphere. Then, a transition metal solution for coprecipitation was replaced with a low nickel content and the coprecipitation reaction proceeded for the desired time. The electrochemical analysis of the core-shell cathode showed a capacity retention of 94 % after 100 cycles, compared to the initial discharge capacity of 184.74 mA h/g. The rate capability test also confirmed that the core-shell cathode had enhanced kinetics during charging and discharging at 1 A/g.

Hydrogen sulfide protects from acute kidney injury via attenuating inflammation activated by necroptosis in dogs

  • Wang, Shuang;Liu, XingYao;Liu, Yun
    • Journal of Veterinary Science
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    • v.23 no.5
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    • pp.72.1-72.14
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    • 2022
  • Background: The treatment of acute kidney injury (AKI), a common disease in dogs, is limited. Therefore, an effective method to prevent AKI in veterinary clinics is particularly crucial. Objectives: Hydrogen sulfide (H2S) is the third gaseous signal molecule involved in various physiological functions of the body. The present study investigated the effect of H2S on cisplatin-induced AKI and the involved mechanisms in dogs. Methods: Cisplatin-injected dogs developed AKI symptoms as indicated by renal dysfunction and pathological changes. In the H2S-treated group, 50 mM sodium hydrosulfide (NaHS) solution was injected at 1 mg/kg/h for 30 min before cisplatin injection. After 72 h, tissue and blood samples were collected immediately. We performed biochemical tests, optical microscopy studies, analysis with test kits, quantitative reverse-transcription polymerase chain reaction, and western blot analysis. Results: The study results demonstrated that cisplatin injection increased necroptosis and regulated the corresponding protein expression of receptor interacting protein kinase (RIPK) 1, RIPK3, and poly ADP-ribose polymerase 1; furthermore, it activated the expressions of inflammatory factors, including tumor necrosis factor-alpha, nuclear factor kappa B, and interleukin-1β, in canine kidney tissues. Moreover, cisplatin triggered oxidative stress and affected energy metabolism. Conversely, an injection of NaHS solution considerably reduced the aforementioned changes. Conclusions: In conclusion, H2S protects the kidney from cisplatin-induced AKI through the mitigation of necroptosis and inflammation. These findings provide new and valuable clues for the treatment of canine AKI and are of great significance for AKI prevention in veterinary clinics.

Fabrication of Polymer Composite with Enhanced Insulation and Mechanical Properties using Aluminum Borate Nanowhiskers (알루미늄 보레이트 나노휘스커를 이용한 향상된 절연성 및 기계적 특성을 가지는 고분자 복합체 제작)

  • Junhyeok Choi;Sangin Lee;Kiho Song;Taekyung Kim;Changui Ahn
    • Journal of Powder Materials
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    • v.30 no.4
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    • pp.356-362
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    • 2023
  • Inorganic-organic composites find extensive application in various fields, including electronic devices and light-emitting diodes. Notably, encapsulation technologies are employed to shield electronic devices (such as printed circuit boards and batteries) from stress and moisture exposure while maintaining electrical insulation. Polymer composites can be used as encapsulation materials because of their controllable mechanical and electrical properties. In this study, we propose a polymer composite that provides good electrical insulation and enhanced mechanical properties. This is achieved by using aluminum borate nanowhiskers (ABOw), which are fabricated using a facile synthesis method. The ABOw fillers are created via a hydrothermal method using aluminum chloride and boric acid. We confirm that the synthesis occurs in various morphologies based on the molar ratio. Specifically, nanowhiskers are synthesized at a molar ratio of 1:3 and used as fillers in the composite. The fabricated ABOw/epoxy composites exhibit a 48.5% enhancement in mechanical properties, similar to those of pure epoxy, while maintaining good electrical insulation.

The Effects of Knee Brace on Anterior Cruciate Ligament Injuries Risk Factors During One-Legged Landing of Female Gymnasts (여자 체조선수들의 한 발 드롭 착지 시 무릎보호대가 전방십자인대 부상 위험요인에 미치는 영향)

  • Lim, Bee-Oh;Kim, Kew-Wan;Seo, Jung-Suk
    • 한국체육학회지인문사회과학편
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    • v.51 no.4
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    • pp.419-425
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    • 2012
  • The purpose of the study was to investigate the effects of knee brace on anterior cruciate ligament injuries risk factors during one-legged landing of female gymnasts. Eleven female gymnasts were recruited and performed randomly one-legged drop landing in height of her's knee with (3times) and without (3times) knee brace. Kinematics and ground reaction data were collected to estimate the anterior cruciate ligament injuries risk factors. Data were analyzed with paired samples t-test. Female gymnasts with knee brace showed more reduced the distance from ankle joint center to knee joint center in sagittal plane and knee maximum joint torque than without knee brace. In conclusion, Female gymnasts with knee brace reduced anterior cruciate ligament stress.

Numerical analyses for mechanical behavior of cut-and-cover tunnel with precast arch type (프리캐스트 아치형 개착식 터널의 역학적 거동에 관한 수치해석)

  • Hwang, Jae-Hong
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.11 no.3
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    • pp.315-325
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    • 2009
  • The thickness of the material can be thinned because arch cut-and-cover tunnel has the support mechanism by the axial force, and the ground reaction force due moderate deformation can be expected thereby making it be dynamically advantageous, therefore the arch cut-and-cover tunnel has become more widely used. An important characteristic of the arch cut-and-cover tunnel is that the thickness of the material can be thinned because precast arch type has the support mechanism by the axial force. However, there is a different stress state surrounding the structures between normally excavated tunnels and cut-and-cover tunnels, it should be considered at designing. Therefore, finite element method was carried out to examine the mechanical behavior of the precast arch cut-and-cover tunnel considering construction procedure.

Surface Engineering of GaN Photoelectrode by NH3 Treatment for Solar Water Oxidation

  • Soon Hyung Kang;Jun-Seok Ha
    • Journal of Electrochemical Science and Technology
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    • v.14 no.4
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    • pp.388-396
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    • 2023
  • Photoelectrochemical (PEC) water splitting is a vital source of clean and sustainable hydrogen energy. Moreover, the large-scale H2 production is currently necessary, while long-term stability and high PEC activity still remain important issues. In this study, a GaN-based photoelectrode was modified by an additional NH3 treatment (900℃ for 10 min) and its PEC behavior was monitored. The bare GaN exhibited a highly crystalline wurtzite structure with the (002) plane and the optical bandgap was approximately 3.2 eV. In comparison, the NH3-treated GaN film exhibited slightly reduced crystallinity and a small improvement in light absorption, resulting from the lattice stress or cracks induced by the excessive N supply. The minor surface nanotexturing created more surface area, providing electroactive reacting sites. From the surface XPS analysis, the formation of an N-Ga-O phase on the surface region of the GaN film was confirmed, which suppressed the charge recombination process and the positive shift of EFB. Therefore, these effects boosted the PEC activity of the NH3-treated GaN film, with J values of approximately 0.35 and 0.78 mA·cm-2 at 0.0 and 1.23 VRHE, respectively, and an onset potential (Von) of -0.24 VRHE. In addition, there was an approximate 50% improvement in the J value within the highly applied potential region with a positive shift of Von. This result could be explained by the increased nanotexturing on the surface structure, the newly formed defect/trap states correlated to the positive Von shift, and the formation of a GaOxN1-x phase, which partially blocked the charge recombination reaction.

Multiple effects of nano-silica on the pseudo-strain-hardening behavior of fiber-reinforced cementitious composites

  • Hossein Karimpour;Moosa Mazloom
    • Advances in nano research
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    • v.15 no.5
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    • pp.467-484
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    • 2023
  • Despite the significant features of fiber-reinforced cementitious composites (FRCCs), including better mechanical, fractural, and durability performance, their high content of cement has restricted their use in the construction industry. Although ground granulated blast furnace slag (GGBFS) is considered the main supplementary cementitious material, its slow pozzolanic reaction stands against its application. The addition of nano-sized mineral modifiers, including nano-silica (NS), is an alternative to address the drawbacks of using GGBFS. The main object of this empirical and numerical research is to examine the effect of NS on the strain-hardening behavior of cementitious composites; ten mixes were designed, and five levels of NS were considered. This study proposes a new method, using a four-point bending test to assess the use of nano-silica (NS) on the flexural behavior, first cracking strength, fracture energy, and micromechanical parameters including interfacial friction bond strength and maximum bridging stress. Digital image correlation (DIC) was used for monitoring the initiation and propagation of the cracks. In addition, to attain a deep comprehension of fiber/matrix interaction, scanning electron microscope (SEM) analysis was used. It was discovered that using nano-silica (NS) in cementitious materials results in an enhancement in the matrix toughness, which prevents multiple cracking and, therefore, strain-hardening. In addition, adding NS enhanced the interfacial transition zone between matrix and fiber, leading to a higher interfacial friction bond strength, which helps multiple cracking in the composite due to the hydrophobic nature of polypropylene (PP) fibers. The findings of this research provide insight into finding the optimum percent of NS in which both ductility and high tensile strength of the composites would be satisfied. As a concluding remark, a new criterion is proposed, showing that the optimum value of nano-silica is 2%. The findings and proposed method of this study can facilitate the design and utilization of green cementitious composites in structures.