• 한국콘텐츠학회논문지
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• 제21권4호
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• pp.815-824
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• 2021

본 연구는 간호대학생의 학업스트레스, 대학생활적응, 사회적지지 정도를 파악하고 학업스트레스와 대학생활적응 간에 사회적지지의 매개효과를 파악하고자 하였다. 연구대상은 G광역시 4개 간호대학의 248명이다. 자료는분석은 SPSS 24.0을 사용하여 기술통계, Independent t-test, One-way ANOVA, Pearson's correlation, 부트스트랩으로 분석되었다. 연구결과 학업스트레스 2.68점, 사회적지지 4.11점, 대학생활적응 3.5점이었다. 학업스트레스는 사회적지지와 대학생활적응에서 음의 상관관계를 보였으며, 사회적지지는 대학생활적응과 양의 상관관계를 보였다. 이는 학업스트레스가 높을수록 대학생활적응과 사회적지지 정도가 낮아지며, 사회적지지가 높을수록 대학생활적응이 높아지는 것이다. 매개효과 검증 모형 모델 4를 적용하여 분석한 결과 첫째, 학업스트레스가 사회적지지에 유의한 부적 영향을 미쳤으며, 둘째, 학업스트레스는 대학생활적응에 대한 부적 영향이 유의하게 낮아졌고, 사회적지지는 대학생활적응에 유의한 정적 영향을 미치는 것으로 검증되었다. 셋째, 학업스트레스와 사회적지지가 대학생활적응에 미치는 총 효과, 직접효과, 간접효과를 분석한 결과 모두 유의한 것으로 나타났다. 결론적으로 학업스트레스와 대학생활적응 사이에서 사회적지지는 부분적으로 조절된 매개효과를 가지고 있는 것으로 확인되었다.

• 한국산학기술학회논문지
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• 제18권5호
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• pp.490-496
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• 2017

본 연구의 목적은 성격5요인과 스트레스 대처방식과의 관계에서 자기효능감의 매개효과를 검증하는 것이다. 이를 위하여 설정된 연구문제는 다음과 같다. 첫째, 성격 5요인과 스트레스 대처방식, 자기효능감의 관계는 어떠한지 분석하였다. 둘째, 성격 5요인 가운데 그 자체가 대학생의 정신건강을 의미하는 변인으로, 임상적 의미가 매우 높은 신경증과 성실성을 선정하여 신경증 및 성실성과 스트레스 대처방식과의 관계에서 자기효능감이 매개역할을 하는지 알아보았다. 이러한 연구문제를 검증하기 위하여 충청지역 D대학 1학년 462명을 대상으로 성격 5요인 척도, 스트레스 대처방식 척도, 자기효능감 척도를 실시하였다. 첫째, 상관 분석 결과 신경증과 자기효능감은 부적 상관을 나타내고, 성실성은 정적 상관을 나타냈다. 그리고 성격5요인과 스트레스 대처방식을 살펴보면 성실성은 스트레스 대처방식 가운데 회피중심과 부적상관을 보였고, 신경증은 스트레스 대처방식 중 사회적지지, 문제해결중심과 부적상관을 보였다. 둘째, 위계적 회귀분석을 사용해 자기효능감의 매개효과를 분석한 결과 자기효능감은 신경증 요인과 회피중심 간에 관계에서만 부분 매개효과가 있음을 나타냈다. 이러한 결과는 대학생의 스트레스 대처를 예측하기 위해 성격5요인이 유용한 심리적 구인이라는 점과 특히 대학생의 정신건강의 예언변수인 신경증 요인과 스트레스 대처방식 가운데 회피성향을 갖고 있는 경우 정신적 스트레스를 줄이기 위해 자기효능감에 대한 교육적 중재의 필요성을 밝혔다는 점에서 의의가 있다.

• Laboraroty Animal Research
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• 제34권4호
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• pp.288-294
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• 2018

A few clues about correlation between endoplasmic reticulum (ER) stress and mulberry (Morus alba) leaves were investigated in only the experimental autoimmune myocarditis and streptozotocin-induced diabetes. To investigate whether a novel extract of mulberry leaves fermented with Cordyceps militaris (EMfC) could suppress ER in fatty liver, alterations in the key parameters for ER stress response were measured in high fat diet (HFD)-induced obese C57L/6 mice treated with EMfC for 12 weeks. The area of adipocytes in the liver section were significantly decreased in the HFD+EMfC treated group as compared to the HFD+Vehicle treated group, while their level was higher in HFD+Vehicle treated group than No treated group. The level of the eukaryotic initiation factor 2 alpha ($eIF2{\alpha}$) and inositol-requiring enzyme 1 beta ($IRE1{\alpha}$) phosphorylation and CCAAT-enhancer-binding protein homologous protein (CHOP) expression were remarkably enhanced in the HFD+Vehicle treated group. However, their levels were restored in the HFD+EMfC treated group, although some differences were detected in the decrease rate. Similar recovery was observed on the ER stress-induced apoptosis. The level of Caspase-3, Bcl-2 and Bax were decreased in the HFD+EMfC and HFD+orlistat (OT) treated group compared to the HFD+Vehicle treated group. The results of the present study therefore provide first evidence that EMfC with the anti-obesity effects can be suppressed ER stress and ER stress-induced apoptosis in the hepatic steatosis of HFD-induced obesity model.

• BMB Reports
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• 제50권8호
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• pp.393-400
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• 2017

Plants are constantly exposed to a variety of abiotic stresses, such as drought, heat, cold, flood, and salinity. To survive under such unfavorable conditions, plants have evolutionarily developed their own resistant-mechanisms. For several decades, many studies have clarified specific stress response pathways of plants through various molecular and genetic studies. In particular, it was recently discovered that ubiquitin proteasome system (UPS), a regulatory mechanism for protein turn over, is greatly involved in the stress responsive pathways. In the UPS, many E3 ligases play key roles in recognizing and tethering poly-ubiquitins on target proteins for subsequent degradation by the 26S proteasome. Here we discuss the roles of RING ligases that have been defined in related to abiotic stress responses in plants.

• Journal of Applied Biological Chemistry
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• 제64권2호
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• pp.141-151
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• 2021

Insects affect crop harvest yield and quality, making plant response mechanisms to insect herbivores a heavily studied topic. However, analysis of plant responses to honeybees is rare. In this study, comprehensive metabolic profiling of Arabidopsis thaliana exposed to honeybees was performed to investigate which metabolites were changed by the insect. A total of 85 metabolites-including chlorophylls, carotenoids, glucosinolates, policosanols, tocopherols, phytosterols, β-amyrin, amino acids, organic acids, sugars, and starch-were identified using high performance liquid chromatography, gas chromatography-mass spectrometry, and gas chromatography-time-of-flight mass spectrometry. The metabolite profiling analysis of Arabidopsis exposed to honeybees showed higher levels of stress-related metabolites. The levels of glucosinolates (glucoraphanin, 4-methoxyglucobrassicin), policosanols (eicosanol, docosanol, tricosanol, tetracosanol), tocopherols (β-tocopherol, γ-tocopherol), putrescine, lysine, and sugars (arabinose, fructose, glucose, mannitol, mannose, raffinose) in Arabidopsis exposed to honeybees were higher than those in unexposed Arabidopsis. Glucosinolates act as defensive compounds against herbivores; policosanols are components of plant waxes; tocopherols act as an antioxidant; and putrescine, lysine, and sugars contribute to stress regulation. Our results suggest that Arabidopsis perceives honeybees as a stress and changes its metabolites to overcome the stress. This is the first step to determining how Arabidopsis reacts to exposure to honeybees.

• 한국간호교육학회지
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• 제21권3호
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• pp.289-297
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• 2015

Purpose: The purpose of this study was to describe stress levels, stress coping methods, and college adjustment according to behavior styles in freshman nursing students. Methods: Data were collected through a structured questionnaire targeting general characteristics, behavior styles, stress levels, stress coping methods, and college adjustment, and were analyzed with descriptive statistics, ANOVA, t-tests, and Pearson correlation using the SPSS program. Results: Stress was related to perceived physical health status, satisfaction with school life, and behavior style. Problem-focused coping was related to exercise, satisfaction with school life, and behavior style. College adjustment was related to place of residence, personality, perceived physical health status, motivation for entrance, and satisfaction with school life. College adjustment had significant positive correlations with stress and problem-focused coping. The relationship between college adjustment and hopeful-thought coping had a significantly negative correlation. Conclusion: These results suggest that identifying the effects of self-understanding programs on stress management and college adjustment is required.

• 한국생명과학회:학술대회논문집
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• 한국생명과학회 2007년도 제48회 학술심포지움 및 추계국제학술대회
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• pp.126.1-126.1
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• 2007

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• 한국응급구조학회지
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• 제17권3호
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• pp.87-100
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• 2013

purpose: This study aims to understand the relationship between stress in college life, vulnerability to depression, and smartphone overuse among undergraduate students majoring in public health. Methods: The subjects of the study were 320 students who were selected through convenience sampling from the department of emergency medical technology, physical therapy, and public health and administration attending G University in Gwangju. The study was carried out from October 22 to 26, 2012. For final analysis, 266 copies were used. Statistical analysis was done using SPSS WIN 12.0. Results: Excessive use of smartphones had a negative effect on stress in college life and vulnerability to depression. The stress of college life had an effect on students' sense of value, their friends of the same sex, and job. Depressive vulnerability had an effect on a students' dependency. Conclusion: For the prevention of smartphone overuse, programs to prevent college life stress and vulnerability to depression should be developed. Counselling programs for the groups should be made available to the students.

• Child Health Nursing Research
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• 제18권4호
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• pp.157-163
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• 2012

Purpose: This study was conducted to identify the effects of life stress and depression in undergraduates on suicidal ideation. Methods: The participants in this study were 306 nursing students from three different cities. Collected data were analyzed using t-test, ANOVA, Pearson correlation coefficients, and stepwise multiple regression. Results: The mean score for life stress was 48.48, for depression, 28.59, and for suicidal ideation, 5.90. There were positive relationships between depression and life stress, suicidal ideation and life stress, and suicidal ideation and depression. The four factors of life stress, depression, school life, and gender were identified as factors influencing on suicidal ideation in undergraduates. Conclusion: The findings of this study indicate that the establishment of mental health care centers in universities, and development and implementation of nursing intervention programs for suicide prevention would be helpful.

• 재활간호학회지
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• 제15권2호
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• pp.73-82
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• 2012

Purpose: The purpose of this study was to identify the influencing factors on mental health related quality of life (MHRQoL) in adults across the lifespan. Methods: A total of 688 Korean adults aged 19 years and older were selected. Data were collected by personal interviews or self report using structured questionnaires. For data analysis, t-test, ANOVA, Pearson's correlation coefficients and Stepwise multiple regression were used. Results: Mental health related quality of life (MHRQoL) differed significantly according to life cycle, especially showing a lower score in the elderly than others. In addition, elderly adulthood reported the highest stress and depression. The most significant predictors of MHRQoL in young and middle aged people were stress, depression, and subjective health status. Predictors of MHQoL in the elderly were stress and religion. Conclusion: The results indicate that MHRQoL of adult is associated with stress and depression. When the programs are developed to enhance mental health in elderly adulthood, religion should be considered as well as stress.