• Title/Summary/Keyword: Stress increment

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Preparation and Evaluation of Mutivitamin Emulsion (복합비타민 유제의 제조와 평가)

  • Lee, Moon-Seok;Cho, Hea-Young;Lee, Yong-Bok
    • Journal of Pharmaceutical Investigation
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    • v.32 no.1
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    • pp.13-19
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    • 2002
  • Water-lipid soluble multivitamin formulations were widely used to reduce the disease and stress of animals as husbandry has made a remarkable progress in recent. But the efficiency of these formulations is far from satisfactory. So, this study was attempted to develop the physically and chemically stable and useful multivitamin o/w emulsion. Multivitamin o/w emulsion composed of water, soybean oil (10%, v/v), vitamin A, D, E, K, $B_2,\;B_6,\;B_{12}$ and panthenol. To make a stable o/w emulsion, the egg lecithin (2%, w/v) and glycerin (2.5%, w/v) were used for emulsifier and thickening agent, respectively. The oil in water emulsion system was manufactured by microfluidizer and the physicochemical stability of this emulsion was evaluated. The average particle size and interfacial tension were measured. From the result of interfacial tension tested, critical micelle concentration of the egg lecithin was 0.5% (w/v) and optimal concentration for the preparation of emulsion was 2% (w/v). The mean particle size was about $0.6\;{\mu}m$ which was suitable for injections. Short-term accelerated stability as physical stability study was tested by centrifuging and freeze-thawing the emulsion samples. The additions of vitamins resulted in the increment of particle size and reduction of physical stability of emulsion. But it is not an enormous problem for the stability of emulsion. Also, we have performed the long-period preservation stability test for the vitamins. All vitamins were analysed by HPLC. The result of storage under $4^{\circ}C$ and dark conditions demonstrated that all vitamins were maintained stable at least 16 weeks, except for vitamin $B_{12}$.

Effect of Premenstrual Syndrome on Work-Related Quality of Life in Turkish Nurses

  • Kahyaoglu Sut, Hatice;Mestogullari, Elcin
    • Safety and Health at Work
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    • v.7 no.1
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    • pp.78-82
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    • 2016
  • Background: Little is known about the effects of premenstrual syndrome (PMS) on work-related quality of life in nurses. We aimed to investigate the effect of PMS on work-related quality of life in Turkish nurses. Methods: A total of 134 volunteer nurses were included in this cross-sectional study between January 2015 and March 2015. One hundred and thirty-four nurses completed a questionnaire regarding demographic data, the Premenstrual Syndrome Scale (PMSS), and the Work-Related Quality of Life Scale (WRQoL). The nurses were classified as having or not having premenstrual syndrome according to the PMSS. Results: The average age was $29.5{\pm}7.1years$ and the prevalence of PMS was 38.1%. The total score of PMSS was significantly negatively correlated with the overall score (r = -0.341; p < 0.001) and all subscale scores of the WRQoL and ranged from -0.207 to -0.402 (p < 0.05 for all). All of the WRQoL subscale scores except stress at work (p = 0.179) in nurses with PMS were significantly lower than those of nurses without PMS (p < 0.05). The age (${\beta}=-0.258$; p = 0.021) and PMSS total score (${\beta}=-0.314$; p < 0.001) increment negatively; however, optimistic thinking (${\beta}=0.228$; p = 0.008) positively affected overall WRQoL score. Conclusion: Nurses with PMS have decreased levels of work-related quality of life in their professional lives. Methods to help cope with cyclic premenstrual symptoms may be used, and as a result, productivity and work-related quality of life may increase.

Finite Element Analysis of Structural Performance of Anti-Freezing Layer via the Korea Pavement Research Program (한국형포장설계프로그램 및 유한요소해석을 이용한 동상방지층의 구조적 성능 평가)

  • Kim, Dowan;Lee, Junkyu;Mun, Sungho
    • International Journal of Highway Engineering
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    • v.18 no.2
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    • pp.83-90
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    • 2016
  • PURPOSES : Nowadays, cavity phenomena occur increasingly in pavement layers of downtown areas. This leads to an increment in the number of potholes, sinkholes, and other failure on the road. A loss of earth and sand from the pavement plays a key role in the occurrence of cavities, and, hence, a structural-performance evaluation of the pavement is essential. METHODS: The structural performance was evaluated via finite-element analysis using KPRP and KICTPAVE. KPRP was developed in order to formulate a Korean pavement design guide, which is based on a mechanical-empirical pavement design guide (M-EPDG). RESULTS: Installation of the anti-freezing layer yielded a fatigue crack, permanent deformation, and international roughness index (IRI) of 13%, 0.7 cm, and 3.0 m/km, respectively, as determined from the performance analysis conducted via KPRP. These values satisfy the design standards (fatigue crack: 20%, permanent deformation: 1.3 cm, IRI: 3.5 m/km). The results of FEM, using KICTPAVE, are shown in Figures 8~12 and Tables 3~5. CONCLUSIONS: The results of the performance analysis (conducted via KPRP) satisfy the design standards, even if the thickness of the anti-freezing layer is not considered. The corresponding values (i.e., 13%, 0.7 cm, and 3.0 m/km) are obtained for all conditions under which this layer is applied. Furthermore, the stress and strain on the interlayer between the sub-grade and the anti-freezing layer decrease gradually with increasing thickness of the anti-freezing layer. In contrast, the strain on the interlayer between the sub-base and the anti-freezing layer increases gradually with this increase in thickness.

Stress-Strain-Strength Characteristics of Frozen Sands with Various Fine Contents (세립분 함유량에 따른 동결 사질토의 응력-변형률-강도 특성)

  • Chae, Deokho;Hwang, Bumsik;Cho, Wanjei
    • Journal of the Korean GEO-environmental Society
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    • v.16 no.6
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    • pp.31-38
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    • 2015
  • Recently, the participation on the development of the natural gas pipeline in Russia as well as the recent construction of the second Korean Antarctic research station, the Jangbogo station provide the research interests on the behavior of the permafrost ground. To investigate the effect of fines on the mechanical responses of frozen sands, unconfined compression tests were performed on the frozen sands with 0, 5, 10 and 15% of fine contents at -5, -10 and $-15^{\circ}C$. The poorly graded (SP) Joomunjin sand and kaolinite, silt with low plasticity (ML) were used for the preparation of the frozen soil specimens. The mechanical responses of the tested soils were investigated via unconfined compression tests in the temperature controlled laboratory and analyzed in terms of peak unconfined compressive strength and secant modulus at 50% of the peak strength. As the fine contents increase, the unfrozen water contents increase and thus the strength and stiffness of frozen soils decrease. The increment of the stiffness and strength due to the temperature decrease vary with the fine contents.

Undrained shear strength and microstructural characterization of treated soft soil with recycled materials

  • Al-Bared, Mohammed A.M.;Harahap, Indra S.H.;Marto, Aminaton;Abad, Seyed Vahid Alavi Nezhad Khalil;Ali, Montasir O.A.
    • Geomechanics and Engineering
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    • v.18 no.4
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    • pp.427-437
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    • 2019
  • Waste materials are being produced in huge quantities globally, and the usual practice is to dump them into legal or illegal landfills. Recycled tiles (RT) are being used in soil stabilisation which is considered as sustainable solution to reduce the amount of waste and solve the geotechnical problems. Although the stabilisation of soil using RT improved the soil properties, it could not achieve the standard values required for construction. Thus, this study uses 20% RT together with low cement content (2%) to stabilise soft soil. Series of consolidated undrained triaxial compression tests were conducted on untreated and RT-cement treated samples. Each test was performed at 7, 14, and 28 days curing period and 50, 100, and 200 kPa confining pressures. The results revealed an improvement in the undrained shear strength parameters (cohesion and internal frication angle) of treated specimens compared to the untreated ones. The cohesion and friction angle of the treated samples were increased with the increase in curing time and confining pressure. The peak deviator stress of treated samples increases with the increment of either the effective confining pressures or the curing period. Microstructural and chemical tests were performed on both untreated and RT-cement treated samples, which included field emission scanning electron microscopic (FESEM), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), and energy dispersive X-ray spectrometer (EDX). The results indicated the formation of cementation compounds such as calcium aluminium hydrate (C-A-H) within the treated samples. Consequently, the newly formed compounds were responsible for the improvement observed in the results of the triaxial tests. This research promotes the utilisation of RT to reduce the amount of cement used in soil stabilisation for cleaner planet and sustainable environment.

Mechanical behaviour of waste powdered tiles and Portland cement treated soft clay

  • Al-Bared, Mohammed A.M.;Harahap, Indra S.H.;Marto, Aminaton;Abad, Seyed Vahid Alavi Nezhad Khalil;Mustaffa, Zahiraniza;Ali, Montasir O.A.
    • Geomechanics and Engineering
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    • v.19 no.1
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    • pp.37-47
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    • 2019
  • The main objective of this study is to evaluate and compare the efficiency of ordinary Portland cement (OPC) in enhancing the unconfined compressive strength of soft soil alone and soft soil mixed with recycled tiles. The recycled tiles have been used to treat soft soil in a previous research by Al-Bared et al. (2019) and the results showed significant improvement, but the improved strength value was for samples treated with low cement content (2%). Hence, OPC is added alone in this research in various proportions and together with the optimum value of recycled tiles in order to investigate the improvement in the strength. The results of the compaction tests of the soft soil treated with recycled tiles and 2, 4, and 6% OPC revealed an increment in the maximum dry density and a decrement in the optimum moisture content. The optimum value of OPC was found to be 6%, at which the strength was the highest for both samples treated with OPC alone and samples treated with OPC and 20% recycled tiles. Under similar curing time, the strength of samples treated with recycled tiles and OPC was higher than the treated soil with the same percentage of OPC alone. The stress-strain curves showed ductile plastic behaviour for the untreated soft clay and brittle behaviour for almost all treated samples with OPC alone and OPC with recycled tiles. The microstructural tests indicated the formation of new cementitious products that were responsible for the improvement of the strength, such as calcium aluminium silicate hydrate. This research promotes recycled tiles as a green stabiliser for soil stabilisation capable of reducing the amount of OPC required for ground improvement. The replacement of OPC with recycled tiles resulted in higher strength compared to the control mix and this achievement may results in reducing both OPC in soil stabilisation and the disposal of recycled tiles into landfills.

Toxic effects of ammonia on the survival, growth, and oxidative and immune responses in the Pacific abalone, Haliotis discus hannai

  • Park, Hee-Ju;Yu, Young-Bin;Choi, Jae-Ho;Lee, Ju-Hyeong;Kang, Ju-Chan
    • Fisheries and Aquatic Sciences
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    • v.24 no.2
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    • pp.89-98
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    • 2021
  • The accumulation of ammonia, a consequence of intensive aquaculture activity, can damage cultured animals. We analyzed the survival rates, growth, antioxidant responses, and immune responses of abalones, Haliotis discus hannai (mean shell length 70.2 ± 4.9 mm; mean body weight 36.9 ± 3.6 g), biweekly for four weeks, to determine the accumulated concentrations of ammonia (0, 0.1, 0.2, 0.4, 0.8, and 1.6 mg/L). In our biweekly measurements, a survival rate of ≥ 95% was observed for all concentrations of ammonia. The specific growth rate (SGR) decreased at ≥ 0.8 mg/L (p < 0.05), but the daily increment in shell length (DISL) showed no significant change (p < 0.05). Regarding antioxidant responses, the superoxide dismutase (SOD) activity of the hepatopancreas was increased at ammonia concentrations over 0.8 and 0.2 mg/L (p < 0.05) at two and four weeks, respectively, and the SOD activity of the gills increased at concentrations over 0.4 and 1.6 mg/L (p < 0.05) at four weeks. The catalase (CAT) activity of the hepatopancreas and gills increased at ammonia concentrations > 0.8 mg/L (p < 0.05). Phenoloxidase (PO) activity increased at ammonia concentrations over 0.8 mg/L (p < 0.05), and Lysozyme (LZM) increased at concentrations over 0.8 and 0.4 mg/L (p < 0.05). Overall, our findings indicated that ammonia concentrations over 0.8 mg/L in seawater might damage the SGR, antioxidant responses, and immune responses in H. discus hannai. Our findings suggest the necessity of improvement or reinstallation for abalone aquaculture systems and can be used to assess the toxic effects of ammonia on H. hannai.

Influence of Alkali and Silane Treatment on the Physico-Mechanical Properties of Grewia serrulata Fibres

  • JAIN, Bhupesh;MALLYA, Ravindra;NAYAK, Suhas Yeshwant;HECKADKA, Srinivas Shenoy;PRABHU, Shrinivasa;MAHESHA, G.T.;SANCHETI, Gaurav
    • Journal of the Korean Wood Science and Technology
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    • v.50 no.5
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    • pp.325-337
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    • 2022
  • Grewia serrulata fibres were chemically treated with 3%, 6%, and 9% NaOH for the duration of 4 h. Additionally, the NaOH-treated fibres were also treated with 3 - (trimethoxysilyl) propyl methacrylate (silane). Properties such as density and tensile strength of the treated fibres were compared against the untreated fibres. The highest density was obtained in the case of 9% NaOH + silane treated fibres, which was 26.47% higher than untreated fibres, implying effective removal of hemicellulose. Likewise, the highest tensile strength was also obtained in the case of 9% NaOH + silane treated fibres. The increment observed in the tensile strength of the natural fibres was related to the removal of impurities, hemicellulose, and stress-raisers as well as deposition over the fibre surface that smoothed it. These observations were further validated by estimating changes in chemical constituents due to chemical treatment along with characterization techniques such as scanning electron microscopy and thermogravimetric analysis.

Remedy effects of dandelion and milk thistle on fatty liver hemorrhagic syndrome in laying hens

  • Young-Joon Cho;Jeong-Ran Min;Jeong-Hee Han;Sang-Hee Jeong
    • Korean Journal of Veterinary Service
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    • v.46 no.1
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    • pp.1-13
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    • 2023
  • Fatty liver hemorrhagic syndrome (FLHS) is a metabolic disorder found in caged layer hens and causes reduced egg production and sudden death. Dandelion (Taraxacum coreanum, TC) and milk thistle (Cirsium japonicum var. ussuriense, CJ) are well known wild herbs inhabiting Korean peninsula and presenting antioxidative effects. This study investigated alleviate effects of these herbal mixture (6:4, w/w) composed of dried powder of TC and CJ against fatty liver in laying hens. The herbs mixture 5.0, 10.0, 20.0 or 40.0 g/kg feed was provided via feed admixture for 3 weeks to laying hens having FLHS. FLHS was induced by intramuscular injection of β-estradiol (2 mg/kg bw) 2 times per week for 3 weeks and supply with high caloric feed. Egg production rate was reduced from 76.2% at pre-treatment to 49.4% at 1 week and further decreased according to β-estradiol treatment. Increment of serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), total cholesterol (T-Chol) and total bilirubin (T-Bil) and decrement of serum superoxide dismutase (SOD) and glutathione peroxidase (GPX) with fatty liver were found by the treatment of β-estradiol. Supplementation of TC and CJ mixture via feed admixture recovered the reduction of egg production and attenuated serological changes and gross and pathological lesions of fatty liver with the best amelioration effects at 5 and 10 g TC and CJ mixture per kg feed. In conclusion, TC and CJ mixture attenuates FLHS by means of antioxidative effects. Further mechanistic study is required to explain TC and CJ's amelioration effects against FLHS in laying hens.

J2-bounding Surface Plasticity Model with Zero Elastic Region (탄성영역이 없는 J2-경계면 소성모델)

  • Shin, Hosung;Oh, Seboong;Kim, Jae-min
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.43 no.4
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    • pp.469-476
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    • 2023
  • Soil plasticity models for cyclic and dynamic loads are essential in non-linear numerical analysis of geotechnical structures. While a single yield surface model shows a linear behavior for cyclic loads, J2-bounding surface plasticity model with zero elastic region can effectively simulate a nonlinearity of the ground response with the same material properties. The radius of the yield surface inside the boundary surface converged to 0 to make the elastic region disappear, and plastic hardening modulus and dilatancy define plastic strain increment. This paper presents the stress-strain incremental equation of the developed model, and derives plastic hardening modulus for the hyperbolic model. The comparative analyses of the triaxial compression test and the shallow foundation under the cyclic load can show stable numerical convergence, consistency with the theoretical solution, and hysteresis behavior. In addition, plastic hardening modulus for the modified hyperbolic function is presented, and a methodology to estimate model variables conforming 1D equivalent linear model is proposed for numerical modeling of the multi-dimensional behavior of the ground.