• 한국미생물·생명공학회지
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• 제21권4호
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• pp.322-328
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• 1993

During the screening of antifungal compounds from microbial secondary metabolites to control phytophthora blight of red pepper caused by Phytophthora capsici, a soil isolate, strain 38D10 was selected. Based on taxonomic studies, this strain was identified as Streptomyces neyagawaensis. The antifungal compound was purified from culture broth by HP-20 column chromatography, ethyl acetate extraction, silica gel column chromatography, HPLC and identified as concanamycin B by UV. $^1H$-NMR, $^{13}C$-NMR, SIMS analysis. Concanamycin B has strong antifungal activity against some phytopathogenic fungi but not antivacterial activity and preventive value were 50% and 100% at 125ppm and 250ppm in pot assay.

• Journal of Microbiology and Biotechnology
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• 제7권5호
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• pp.329-332
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• 1997

Cell-free extracts of Streptomyces neyagawaensis SL-387 grown on a chemically defined medium supplemented with DL-3-amino-3-phenylpropionic acid (APP) produced N-acetyl-APP (Ac-APP) in the presence of APP and acetyl coenzyme A. The APP obtained by acid hydrolysis of the Ac-APP was D-configuration: $[\alpha]_D+6.5^{\circ}(H_2O)\;at\;20^{\circ}C$, optical purity 92% enantiomeric excesses (ee). These results suggest that an N-acetyltransferase exists in the cell-free extract as a novel enzyme with specificity for D-APP.

• Applied Biological Chemistry
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• 제38권3호
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• pp.196-201
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• 1995

토양으로부터 분리한 신규의 aminopeptidase M 저해제 MR-387A 및 B를 생산하는 균주 SL-387의 화학동정 및 수리동정을 하였다. 배양학적 및 형태학적 특성과 화학지표에 의하여 분리균주는 Streptomyces에 속하는 것으로 판단되었다. 종의 동정을 위하여 41개 동정 단위형질에 대하여 조사한 후 TAXON 프로그램을 사용하여 수리동정을 하였다. 분리균주는 Streptomyces의 주군집 18에 속하는 균주로 Streptomyces eyagawaensis와 공유도계수($S_{SM}$) 75.6%로 가장 유사 하였다. 이상의 화학동정 및 TAXON 분석에 의하여 분리균주 SL-387은 Streptomyces neyagawaensis이거나 그 유연 균주인 것으로 동정 되었다.