Microbiology and Biotechnology Letters (한국미생물·생명공학회지)

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
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Concanamycin B, Active substance Against Phytophthora capsici Produced by Streptomyces neyagawaensis 38D10 Strain

Streptomyces neyagawaensis 38D10 균주가 생산하는 concanamycin B의 항고추역병 활성

  • 김창진 (한국과학기술연구원 유전공학연구소) ;
  • 이인경 (한국과학기술연구원 유전공학연구소) ;
  • 윤봉식 (한국과학기술연구원 유전공학연구소) ;
  • 유익동 (한국과학기술연구원 유전공학연구소)
  • Published : 1993.08.01
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Abstract

During the screening of antifungal compounds from microbial secondary metabolites to control phytophthora blight of red pepper caused by Phytophthora capsici, a soil isolate, strain 38D10 was selected. Based on taxonomic studies, this strain was identified as Streptomyces neyagawaensis. The antifungal compound was purified from culture broth by HP-20 column chromatography, ethyl acetate extraction, silica gel column chromatography, HPLC and identified as concanamycin B by UV. $^1H$-NMR, $^{13}C$-NMR, SIMS analysis. Concanamycin B has strong antifungal activity against some phytopathogenic fungi but not antivacterial activity and preventive value were 50% and 100% at 125ppm and 250ppm in pot assay.

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