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The Anti-inflammatory Effect of Skipjack Tuna (Katsuwonus pelamis) Oil in LPS-induced RAW 264.7 Cells and Mouse Models (LPS 유도 RAW 264.7 세포와 마우스 모델에서 참치(Katsuwonus pelamis) 유의 항염증 효과)

  • Kang, Bo-Kyeong;Kim, Min-Ji;Kim, Koth-Bong-Woo-Ri;Ahn, Na-Kyung;Choi, Yeon-Uk;Bark, Si-Woo;Pak, Won-Min;Kim, Bo-Ram;Park, Ji-Hye;Bae, Nan-Young;Ahn, Dong-Hyun
    • Microbiology and Biotechnology Letters
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    • v.43 no.1
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    • pp.45-55
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    • 2015
  • This study was carried out to demonstrate the anti-inflammatory effect of tuna oil (TO) using LPS-induced inflammation responses and mouse models. First, nitric oxide (NO) and pro-inflammatory cytokines levels were suppressed up to 50% with increasing concentrations of TO without causing any cytotoxicity. Also, the expression of a variety of proteins, such as inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2) and nuclear factor kappa B (NF-κB), was suppressed in a dosedependent manner by treatment with TO. Furthermore, TO also inhibited the phosphorylation of mitogen-activated protein kinases (MAPKs), including c-Jun N-terminal kinase (JNK), extracellular signal-regulated kinase (ERK), and p38 protein kinase (p38). Moreover, in in vivo testing the formation of ear edema was reduced at the highest dose tested compared to that in the control, and a reduction of ear thickness and the number of mast cells was observed in histological analysis. In acute toxicity test, no mortalities occurred in mice administrated 5,000 mg/kg body weight of TO over a two-week observation period. Our results suggest that TO has a considerable anti-inflammatory property through the suppression of inflammatory mediator productions and that it could prove to be useful as a potential anti-inflammatory therapeutic material.

Three Dimensional Analysis Using Digital Elevation Model on the Coastal Landform of the Sacheon Bay, South Sea of Korea (수치고도 모델을 이용한 사천만 해안지역의 3차원 지형분석)

  • Lee, Min-Boo;Kim, Nam-Shin;Han, Kyun-Hyeung
    • Journal of the Korean association of regional geographers
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    • v.9 no.2
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    • pp.203-216
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    • 2003
  • The process of constructing coastal digital elevation model(DEM), for the 3 dimensional analysis, is composed by abstracting land layers for land elevation and water depth, reprojecting UTM, relocating geographical grid, and interpolating works. The geomorphic set of shallow sea, including tidal current, tidal zone deposition, and water depth distribution, was analyzed by eye search of Landsat TM image, masking of land zone, band combination and regression analysis. Some horizontal differences, between combined DEM and surveyed data of shallow sea, was corrected for analysis. Analyzed geomorphic elements are stream channel, alluvial fan, coastal terrace, tidal current. and shallow sea bank. Results of analysis present that transported fluvial materials influence tidal sedimentation, especially from Gahwacheon river, for the role of artificial draining flooding waters from Jinyang Reservoir, almost in the summer season. In the coastal area with less tidal current, more fine materials are deposited. The influence of currental deposition are higher on small pockets with west coast of well developed terraces. The lower skirt of alluvial fans developed into the tidal zone of shallow sea. Small pocket type bays are closed by coastal current, and less influenced from tidal deposition. The bank of Jinju Bay are developed originally from submerging of remnant erosional mountain ranges, and play on the role of trapping fine materials.

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An Integrated Hierarchical Temporal Memory Network for Multi-interval Prediction of Data Streams (데이터 스트림의 다중-간격 예측을 위한 통합된 계층형 시간적 메모리 네트워크)

  • Diao, Jian-Hua;Bae, Sun-Gap;Sim, Myung-Sun;Bae, Jong-Min;Kang, Hyun-Syug
    • Journal of KIISE:Software and Applications
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    • v.37 no.7
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    • pp.558-567
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    • 2010
  • There is a large body of ongoing research to develop efficient prediction methods for data streams. These methods provide single prediction with a fixed time interval. It is necessary to develop a method for multi-interval prediction (MIP) because different prediction results may be obtained based on different intervals in many cases. In this paper, we propose a solution for MIP based on the Hierarchical Temporal Memory (HTM) model. In order to solve the problem of MIP with HTM, we present an Integrated Hierarchical Temporal Memory (IHTM) network by introducing a new node type Zeta1LastNode to the original HTM network. Using the hierarchical characteristic of the IHTM network, different levels in the network learn and model the features of a data stream with different intervals and generate prediction results for different intervals. Performance evaluation shows that the IHTM is efficient in the memory and time consumption compared with the original HTM network in MIP.

On the Determination of Slope Stability to Landslide by Quantification(II) (수량화(數量化)(II)에 의한 산사태사면(山沙汰斜面)의 위험도(危險度) 판별(判別))

  • Kang, Wee Pyeong;Murai, Hiroshi;Omura, Hiroshi;Ma, Ho Seop
    • Journal of Korean Society of Forest Science
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    • v.75 no.1
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    • pp.32-37
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    • 1986
  • In order to get the fundamental information that could be useful to judge the potentiality of occurrence of rapid shallow landslide in the objective slope, factors selected on Jinhae regions in Korea, where many landslides were caused by heavy rainfall of daily 465 mm and hourly 52mm in August 1979, was carried out through the multiple statistics of quantification method (II) by the electronic computer. The net system with $2{\times}2cm$ unit mesh was overlayed with the contour map of scale 1:5000. 74 meshes of landslides and 119 meshes of non-landslide were sampled out to survey the state of vegetative cover and geomorphological conditions, those were divided into 6 items arid 27 categories. As a result, main factors that would lead to landslide were shown in order of vegetation, slope type, slope position, slope, aspect and numbers of stream. Particularly, coniferous forest of 10 years old, concave slope and foot of mountain were main factors making slope instability. On the contrary, coniferous forest of 20-30 years old, deciduous forest, convex slope and summit contributed to the stable against Landslide. The boundary value between two groups of existence and none of landslides was -0.123, and its prediction was 72%. It was well predicted to divide into two groups of them.

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An Analysis of Land Use Patterns in Riparian Zones for the Geumho River Watershed Management (금호강 유역관리를 위한 수변구역의 토지이용패턴분석)

  • Park, Kyung-Hun;Oh, Jeong-Hak;Jung, Sung-Gwan
    • Journal of the Korean Association of Geographic Information Studies
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    • v.8 no.2
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    • pp.157-165
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    • 2005
  • The purpose of this study is to examine the relationship between land use patterns of riparian zones and water quality in the Geumho River watershed. A GIS database included digital land use maps (1:25,000), stream network extracted from digital topographic maps (1:5,000) and riparian zones maps by multi-buffering method. Pearson's correlation analysis was used to explain the relationship between the environmental conditions of a 30 meter buffer strip on each side and water quality. According to the result of investigation of riparian-level land use patterns, sub-watersheds on the lower Geumho River including Daegu metropolitan city were mainly developed as urban area such as residential, commercial and industrial ones, while sub-watersheds on the middle Geumho River and the main course of Nakdong River, agricultural ones such as a paddy, a dry field and an orchard. Meanwhile, the area-rate of riparian forests which play an important role in filtering nitrogen, phosphorus and sediment was estimated below the average 16%. The proportion of urban area in a 30 meter riparian bufferstrip had a negative correlation with water quality in each sub-watershed. But the proportion of forest area had a positive correlation with water quality. Henceforth, it is necessary to establish landscape planning for preparing and restoring the riparian buffer zones, concerning land form, soil type, the present land use pattern and economic aspects.

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A Study on Establishment of Technical Guideline of the Installation and Operation for the Biogas Utilization of Power generation and Stream - Design and Operation Guideline (바이오가스 이용 기술지침 마련을 위한 연구(III) - 기술지침(안) 중심으로)

  • Moon, HeeSung;Bae, Jisu;Pack, Hoyeun;Jeon, Taewan;Lee, Younggi;Lee, Dongjin
    • Journal of the Korea Organic Resources Recycling Association
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    • v.26 no.2
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    • pp.95-103
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    • 2018
  • As a guideline for desulfurization and dehumidification pretreatment facility for optimizing utilization of biogas, the $H_2S$ concentration is set at 150 % which can be treated with iron salts, dehumidification is the optimum value for generator operation, and the relative humidity applied at the utilization of biogas in EU is set at 60 %. We have set up the generator facility guidelines to optimize utilization of biogas. The appropriate amount of biogas should be at least 90 % of the total gas generation, and the capacity of generator facility should be set at 20~30 %. In order to equalize the pressure of the incoming gas the generator, a gas equalization tank should be installed and the generator room average temperature should be kept at $45^{\circ}C$ or less. Since the gas is not produced at a certain methane concentration in the digester, the efficiency is lowered. Therefore, it is required to install an air fuel ratio control system according to the change in methane concentration. Therefore, it is necessary to compensate for the disadvantages of biogasification facilities of organic waste resources and optimize utilization of biogas and improve operation of facilities. This study was conducted to optimize biogas utilization of type of organic waste(containing sewage sludge and food waste, animal manure), investigate the facilities problem and propose design, operation guidelines such as pre-treatment facilities and generators.

Habitat assessment of Lamprotula coreana by using physical habitat simulation system (PHABSIM) at the Guem River (Physical habitat simulation system (PHABSIM) 을 이용한 금강의 두드럭조개 (Lamprotula coreana) 서식지 평가)

  • Kim, Dae-Hee;Kim, Kyeong-Hwan;Lee, Won-Ok;Hur, Jun-Wook
    • The Korean Journal of Malacology
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    • v.31 no.4
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    • pp.307-314
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    • 2015
  • This study sampled endangered species, Lamprotula coreana, and surveyed its habitat at the Guem River with three times from June to August 2013. To assess the habitat, this study conducted field survey considering diverse physical conditions of stream, such as pool, run and riffle, and measured transect, water depth, water velocity, substrate structure, and habitat type. When L. coreana collected, length, weight and age were measured. Water velocity, water depth and substrate structure were recorded to develop HSI (habitat suitability index) and performed PHABSIM (physical habitat simulation) to estimate the optimum flow discharge. Water level, flow discharge and transect data were used for habitat assessment, and PHABSIM was applied to calculate WUA (weighed usable area). Shell length was $73.1{\pm}18.4mm$ (28.5-102.0 mm), shell weight was $131.6{\pm}72.3g$ (28.0-281.0 g) and age was two to seven years from L. coreana collected at the upstream of the Guem River. Developed HSI indicated that the optimal habitat for L. coreana was 0.4-0.5 m for water depth, 0.3-0.5 m/s for water velocity and sand to boulder for substrate structure. The optimum ecological flow discharge for L. coreana was 2.1 cms and WUA was $3,730m^2$/1000 m by the result of PHABSIM. Recently, river construction work and habitat disturbance have caused negative impact on the distribution of L. coreana. The result of this study would provide fundamental data for habitat restoration and management of L. coreana.

Spatial distribution of Korea-born adoptees in the United States (미국내 한국 입양아의 공간분포)

  • Park, Soon Ho
    • Journal of the Korean Geographical Society
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    • v.30 no.4
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    • pp.411-428
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    • 1995
  • Intercountry adoption, one type of forced migration, has increased significantly in recent decades. The adoption of Korea-born children by Americans has been the strongest intercountry adoption linkage in the world. The intercountry adoption stream was strongly influenced by intercountry adoption policies, and socio-cultural settings in both South Korea and the United States. Socio-cultural factors in South Korea made local adoption undesirable and helped for abandoned children to be adopted by Americans, while socio-cultural factors in the United States had reduced the number of locally available infants for adoption, and increased the demand for infants from abroad. Distribution of Korea-born adoptees shows concentration in the Pacific Northwest, Upper Midwest and Northeast areas which have not attracted Korean immigrants so generally. The trend of concentration shows some increased importances in the outlying states in the northern United States. The location and activity of agencies shaped the spatial distribution of Korea-born adoptees in the United States.

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Phytoplankton Community in Reservoirs of Yeongsan and Seomjin River Basins, Korea (영산강.섬진강 수계 주요 호소의 식물플랑크톤 군집)

  • Na, Jeong-Eun;Jung, Myoung-Hwa;Cho, In-Sook;Park, Jong-Hwan;Hwang, Kyung-Sub;Song, Hyo-Jeong;Lim, Byung-Jin;La, Geung-Hwan;Kim, Hyun-Woo;Lee, Hak-Young
    • Korean Journal of Environmental Biology
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    • v.30 no.1
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    • pp.39-46
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    • 2012
  • The distributions of phytoplankton community are investigated from 29 reservoirs in Yeongsan and Seomjin River Basins, Korea. As a microalgal flora, a total of 424 species of phytoplankton were identified. They were 157 Chlorophyceae, 161 Bacillariophyceae, 39 Cyanophyceae, and 67 other algal taxa. The phytoplankton diversity were low in stream type reservoirs such as Kumho, Youngsan and Youngam Reservoirs. The population density of phytoplankton ranged from 29 cells $mL^{-1}$ to 53,161 cells $mL^{-1}$. The dominant phytoplankton species more than 20% of total standing crops were $Asterionella$ $formosa$, $Aulacoseira$ $ambigua$, $Aulacoseira$ $distans$, $Aulacoseira$ $granulata$, $Cyclotella$ sp., $Synedra$ $acus$, $Coelastrum$ $reticulatum$, $Pandorina$ $morum$, $Scenedesmus$ $arcuatus$, $Aphanothece$ $clathrata$, $Microcystis$ $aeruginosa$, $Phormidium$ sp. The concentration of chlorophyll $a$ ranged from 0.41 mg $m^{-3}$~220.72 mg $m^{-3}$, and showed highest concentration in Gaecho-je. The concentrations of TN and TP have no clear relationships with chlorophyll $a$ concentrations.

S-XML Transformation Method for Efficient Distribution of Spatial Information on u-GIS Environment (u-GIS 환경에서 효율적인 공간 정보 유통을 위한 S-XML 변환 기법)

  • Lee, Dong-Wook;Baek, Sung-Ha;Kim, Gyoung-Bae;Bae, Hae-Young
    • Journal of Korea Spatial Information System Society
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    • v.11 no.1
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    • pp.55-62
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    • 2009
  • In u-GIS environment, we collect spatial data needed through sensor network and provide them with information real-time processed or stored. When information through Internet is requested on Web based applications, it is transmitted in XML. Especially, when requested information includes spatial data, GML, S-XML, and other document that can process spatial data are used. In this processing, real-time stream data processed in DSMS is transformed to S-XML document type and spatial information service based on web receive S-XML document through Internet. Because most of spatial application service use existing spatial DBMS as a storage system, The data used in S-XML and SDBMS needs transformation between themselves. In this paper, we propose S-XML a transformation method using caching of spatial data. The proposed method caches the spatial data part of S-XML to transform S-XML and relational spatial database for providing spatial data efficiently and it transforms cached data without additional transformation cost when a transformation between data in the same region is required. Through proposed method, we show that it reduced the cost of transformation between S-XML documents and spatial information services based on web to provide spatial information in u-GIS environment and increased the performance of query processing through performance evaluation.

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