• Asian Pacific Journal of Cancer Prevention
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• 제14권5호
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• pp.3117-3121
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• 2013

Objective: Previous epidemiologic studies demonstrated that obesity might associated with the risk of bladder cancer. However, many of the actual association findings remained conflicting. To better clarify and provide a comprehensive summary of the correlation between obesity and bladder cancer risk, we conducted a meta-analysis to summarize results of studies on the issue. Stratified analyses were also performed on potential variables and characteristics. Methods: Studies were identified by searching in PubMed and Wanfang databases, covering all the papers published from their inception to March 10, 2013. Summary relative risks (SRRs) with their corresponding 95% confidence intervals (CIs) were calculated by either random-effect or fixed-effect models. Results: A total of 11 cohort studies were included in our meta-analysis, which showed that obesity was associated with an increased risk for bladder cancer in all subjects (RR=1.10, 95% CI=1.06-1.16; p=0.215 for heterogeneity; $I^2$=24.0%). Among the 9 studies that controlled for cigarette smoking, the pooled RR was 1.09 (95% CI 1.01-1.17; p=0.131 for heterogeneity; $I^2$=35.9%). No significant publication bias was detected (p = 0.244 for Egger's regression asymmetry test). Conclusions: Our results support the conclusion that obesity is associated with the increased risk of bladder cancer. Further research is needed to generate a better understanding of the correlation and to provide more convincing evidence for clinical intervention in the prevention of bladder cancer.

• Asian Pacific Journal of Cancer Prevention
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• 제14권9호
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• pp.5311-5316
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• 2013

A functional polymorphism in the NQO1 gene, featuring a 609C>T substitution,leading to proline to serine amino-acid and enzyme activity changes, has been implicated in cancer risk. However, individually published investigations showed inconclusive results, especially for leukemia. In this study, we therefore performed a meta-analysis of 21 publications with a total of 3,634 cases and 4,827controls, mainly for leukemia. We summarized the data on the association between the NQO1 609C>T polymorphism and risk of leukemia and performed subgroup analyses by ethnicity and leukemia type. We found that the variant TT homozygous genotype o was associated with a modestly increased risk of leukemia (TT versus CT/CC: OR=1.23, 95%CI=1.00-1.51, heterogeneity=0.76; $I^2$=0%). Following further stratified analyses, increased risk was only observed in subgroups of Caucasians. This meta-analysis suggests that the NQO1 609T allele is a high-penetrance risk factor for leukemia in Caucasians. The effect on leukemia may be modified by ethnicity and leukemia type, and the small sample sizes of the subgroup analyses suggest that further larger studies are needed.

• 한국식생활문화학회지
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• 제7권1호
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• pp.1-8
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• 1992

This study was carried out to evaluate Korean eating behavior which is highly correlated with their nutritional status, and to analyze the effect of various factors on eating behavior. The above information was used to develop a nutritional status for Korea. The 2000 Korean people were selected with the stratified random sampling method. This study used a questionaire as instrument tool. The questionaire consists of :1) socio-demographic characteristics of the subjects; 2) the valuation of food and nutrition; 3) the concern of food and nutrition; 4) psychological health condition; 5) physical health condition; 6) nutrient consumption status and 7) analysis of eating behavior. Data were analyzed by using a SPSS PC Package. Significant differences and correlation among variables were determined by the t-test, $x^2-test$, ANOVA, pearson's correlation coefficient and Multiple regression analysis. The results of this study can be summarized as follow, All nutrient intakes were significantly correlated with eating behavior score(p<0.001). Factors such as socio-economic status, valuation and concern on food and nutrition, and psychological health condition had significant relationship with eating behavior. But the physical health condition had no significant effect on it. Multiple regression analysis showed that valuation of food and nutrition made the greatest contribution(35.6% explained) and concern made the second greatest contribution(10.5% explained). The third was education level(9.8% explained), and the forth psychological health condition(1.8% explained).

• 대한조선학회논문집
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• 제56권5호
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• pp.383-388
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• 2019

It is essential to reduce the Infra-red signature for increasing ship's survivability in ship design stage. However the ship's IR signature is quite sensitive to the maritime and atmosphere. Therefore, it is very important to select the marine meteorological data to be applied to the signature analysis. In this study, we selected the three meteorological sample sets from the population of the Korea Meteorological Administration's marine environment data in 2017. These samples were selected through the two-dimensional stratified sampling method, taking into account the geopolitical threats of the Korean peninsula and the effective area of the buoy. These sample sets were applied to three naval ships classified by their tonnage, and then the IR signature analysis was performed to derive the Contrast Radiant Intensity (CRI) values. Based on the CRI values, the validity of each sample set was determined by comparing Cumulative Distribution Function (CDF), and Probability Density Function (PDF). Also, we checked the degree of scattering in each sample set and determined the efficiency of analysis time and cost according to marine meteorological sample sets to confirm the possibility of a probabilistic method. Through this process, we selected the standard for optimization of marine meteorological sample for ship IR signature analysis. Based on this optimization sample, by applying probabilistic method to the management of IR signature for naval ships, the robust design is possible.

• 대한지역사회영양학회지
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• 제11권5호
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• pp.629-641
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• 2006

The objectives of this study were to: (a) examine the overall operating conditions of both government-dominant and non-governmental food bank programs, (b) understand the operational management attributes on the target based on IPA (importance performance analysis) (c) analyze the present status of donating management, and (d) suggest a direction based on the analysis of advantages and disadvantages of food banks in each part. The random samples of 120 food bank operators were selected by a proportionate stratified random sampling method. A total of 60 government-dominant food banks and 25 non-governmental food banks were analyzed. The main results of this study were as follows: Accord-ing to the Importance-Performance Analysis of operational management, 'assistance for operating funds' and 'deployment of experience staff' were placed at 'Focus Here'. There was a great shortage of experienced staff with food bank-specific knowledge. The average number of the government-dominant and non-governmental food bank program employees was 0.29 and 0.30 respectively, while the ratios of employees with other jobs were 0.96 and 0.83 respectively. Shortages of refrigeration facilities were an area that needs to be addressed. While 51.6% of donated food required cold storage, only 45% of government-dominant and 60% of non-governmental food bank programs had refrigeration facilities. Most of food bank operators (96.3%) were required to visit the donators' locations to pick up the donated foods. And the foods were distributed to the people in need, especially to the livelihood protectee.

• 산업경영시스템학회지
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• 제38권4호
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• pp.117-131
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• 2015

Conventional data envelopment analysis (DEA) models require that inputs and outputs are given as crisp values. Very often, however, some of inputs and outputs are given as imprecise data where they are only known to lie within bounded intervals. While a typical approach to addressing this situation for optimization models such as DEA is to conduct sensitivity analysis, it provides only a limited ex-post measure against the data imprecision. Robust optimization provides a more effective ex-ante measure where the data imprecision is directly incorporated into the model. This study aims to apply robust optimization approach to DEA models with imprecise data. Based upon a recently developed robust optimization framework which allows a flexible adjustment of the level of conservatism, we propose two robust optimization DEA model formulations with imprecise data; multiplier and envelopment models. We demonstrate that the two models consider different risks regarding imprecise efficiency scores, and that the existing DEA models with imprecise data are special cases of the proposed models. We show that the robust optimization for the multiplier DEA model considers the risk that estimated efficiency scores exceed true values, while the one for the envelopment DEA model deals with the risk that estimated efficiency scores fall short of true values. We also show that efficiency scores stratified in terms of probabilistic bounds of constraint violations can be obtained from the proposed models. We finally illustrate the proposed approach using a sample data set and show how the results can be used for ranking DMUs.

• 한국습지학회지
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• 제23권2호
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• pp.173-182
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• 2021

수자원의 보전과 관리를 위해서는 갈수시의 유량감쇄 특성을 파악하는 것이 중요한 과제 중에 하나이다. 감쇄특성을 하천 유량자료를 이용하여 표현하기 위해서 여러 복잡한 특성을 고려하여야 하므로, 편의성을 위하여 선형 감쇄분석이 주로 적용되어 왔다. 그러나, 최근의 연구에서 제시된 지하수 유출과 비피압대수층의 저장능력의 비선형성을 고려하면, 비선형 감쇄모형의 적용성이 더 높다고 할 수 있다. 따라서, 본 연구의 목적은 유출자료를 이용하여 지하수의 증발손실, 저류 및 재함양과 같은 비선형 특성을 고찰하는 데 있다. 한강의 상류인 평창강 유역의 유출자료를 이용하여 분석을 수행하였으며, 지하수 수지를 구성하는 주요한 요소인 지하수 유출, 증발손실, 저류, 재함양에 대해서 고찰하고 정량화하였다. 연구결과에 따라서, 식생에 의한 지하수 손실이 감쇄곡선을 편향시키는 것으로 나타났다. 또한, 계절적 강우와 잠재증발산 경향을 감쇄분석에 적용하여 월별 증발산 손실과 지하수 함양량을 정량화하여 제시하였다.

• Journal of Korean Neurosurgical Society
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• 제66권4호
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• pp.438-445
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• 2023

Objective : Preoperative transarterial embolization (TAE) of tumor feeders in hypervascular spine metastasis is known to reduce intraoperative estimated blood loss (EBL) during surgery. The effect of TAE varies for several reasons, and one controllable factor is the timing between embolization and surgery. However, the adequate timing remains unclear. This study aimed to evaluate the timing and other factors that reduce EBL in spinal metastasis surgery through a meta-analysis. Methods : A comprehensive database search was performed to identify direct comparative studies of EBL stratified by the timing of surgery after TAE for spinal metastasis. EBL was analyzed according to the timing of surgery and other factors. Subgroup analyses were also performed. The difference in EBL was calculated as the mean difference (MD) and 95% confidence interval (CI). Results : Among seven studies, 196 and 194 patients underwent early and late surgery after TAE, respectively. The early surgery was defined as within 1-2 days after TAE, while the late surgery group received surgery later. Overall, the MD in EBL was not different according to the timing of surgery (MD, 86.3 mL; 95% CI, -95.5 to 268.1 mL; p=0.35). A subgroup analysis of the complete embolization group demonstrated that patients who underwent early surgery within 24 hours after TAE had significantly less bleeding (MD, 233.3 mL; 95% CI, 76.0 to 390.5 mL; p=0.004). In cases of partial embolization, EBL was not significantly different regardless of the time interval. Conclusion : Complete embolization followed by early spinal surgery within 24 hours may reduce intraoperative bleeding for the patients with hypervascular spinal metastasis.

• Nuclear Engineering and Technology
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• 제56권1호
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• pp.9-18
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• 2024

In-vessel retention through external reactor vessel cooling (IVR-ERVC) is a severe accident management (SAM) strategy that has been adopted and used in many nuclear reactors such as AP1000, APR1400, and light water reactor etc. Some reactor accidents have raised concerns about nuclear reactors among residents, leading to a decrease in residents' acceptability and many studies on SAM are being conducted. Experiments on IVR-ERVC are almost impossible due to its specificity, so fluid characteristics are analyzed through BALI experiments with similar condition. In this study, computational fluid dynamics (CFD) via Reynolds-averaged Navier-Stokes (RANS) and large eddy simulation (LES) for BALI experiments were performed. Steady-state CFD analysis was performed on three turbulence models, and SST k-ω model was in good agreement with the experimental measurement temperature within the maximum error range of 1.9%. LES CFD analysis was performed based on the RANS analysis results and it was confirmed that the temperature and wall heat flux for depth was consistent within an error range of 1.0% with BALI experiment. The LES CFD analysis results were compared with those of the Lagrangian-based solver. LES matched the temperature distribution better than SOPHIA, but SOPHIA calculated the position of boundary between stratified layer and convective layer more accurately. On the other hand, Lagrangian-based solver predicted several small eddy behaviors of the convective layer and LES predicted large vortex behavior. The vibration characteristics near the cooling part of the BALI experimental device were confirmed through Fast Fourier Transform (FFT) investigation. It was found that the power spectral density for pressure at least 10 times higher near the side cooling than near the top cooling.

• 한국해양학회지:바다
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• 제3권1호
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• pp.1-8
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• 1998

하계에 연안혼합역과 외해성층역 사이에서 강력한 표층수온전선이 형성되는 한국 서해 중부의 태안반도 인근해역에서 1994년 7월, 1995년 5원 및 1996년 6월 등 3회에 걸쳐 취득한 해수물성자료를 분석하였다. 수직혼합역은 최저 15 m에서 최고 60 m 이상까지의 다양한 수심의 지형으로 이루어졌으며, 수심에 관계없이 표층과 저층의 수온차가 $1^{\circ}C$ 이내였다. 관측시기에 관계없이 혼합역 내의 수평적인 표층수온차는 작으면서도 수심에 반비례하는 특정을 보이고 표층수온이 가장 낮은 해역은 태안반도 서단에서 남서방향으로 형성되어있는 수심이 50 m 이상인 깊은 수로를 중심으로 관측되었다. 또한 6월에 관측한 표층수온전선이 태양복사열이 더 강한 7월에 관측한 표층수온전선에 비해 더 강한 특성을 보였다. 이러한 관측결과는 연구해역의 표층수온전선역은 수층의 수직혼합에 의해 형성되지만, 수온전선의 강도는 수직혼합역의 수성 및 외해성층역의 수온의 수직구조 등에 의해 결정되는 것으로 해석된다.