• Title/Summary/Keyword: Stomach diseases

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A Case of Triple Primary Cancers in Stomach, Larynx, and Lung (원발성 위암과 후두암, 폐암 병발의 1례)

  • Choi, Ju Young;Chang, Hye Jeong;Lee, Min Jin;Sim, Sung Sin;Ryu, Yon Ju;Moon, Jin Uk;Lee, Jin Hwa;Chun, Eun Mi;Chang, Jung Hyun
    • Tuberculosis and Respiratory Diseases
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    • v.61 no.3
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    • pp.279-284
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    • 2006
  • A multiple primary malignant tumor is a disease mainly encountered in the of the older age groups. Attempts should be made to rule out a second primary malignant neoplasm in the elderly patients with unusual signs and symptoms. We encountered a case of a 67-year-old male with triple primary malignant tumors of the stomach, larynx, and lung. The patient had been treated with a subtotal gastrectomy for early gastric cancer in 1991 and a Laser laryngectomy for the laryngeal squamous cell carcinoma in 2003. In 2005, lung cancer was found with the biopsy revealing an adenosquamous carcinoma. Systemic chemotherapy was performed.

Comparative Study on Influencing Factors and Digestive Symptoms among Upper Gastrointestinal Disease Groups (상부 위장관 질환군별 영향 요인 및 소화기 증상에 관한 비교 연구)

  • Oh, Doo-Nam
    • The Journal of the Korea Contents Association
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    • v.11 no.12
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    • pp.335-346
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    • 2011
  • The aim of this study is to compare the differences of influencing factors and subjective digestive symptoms among upper gastrointestinal disease groups. Subjects of this study are the results of Helicobactor Pylori test, gastrofibroscopic findings, and the electronic data of medical questionnaires on individuals at the age of 20 to 79 who visited a Health Promotion Center in Seoul from October, 2003 to October, 2004. 2,708 cases are analysed for final with $x^2$ test and ANOVA test. The sociodemographic factors of sex, age and occupation, the living habits factors of smoking and drinking, the pathophysiological factor of H. pylori infection, and the psychological factor of stress show statistically significant differences among groups. The digestive symptoms of "the feeling of something remained in the stomach", "the burning feeling right after eating or at the empty state of stomach" and "the frequent reflux of watery acid from the stomach" show statistically significant differences among groups. This study provides meaningful data in finding distinctive features of each disease and will be applied as basic materials to the development of intervention methods for health promotion relating to the upper gastrointestinal diseases.

The Effects of Duchesnea india(Audra.) Foche. on Human Stomach Cancer Cells (사매가 위암세포에 미치는 영향)

  • Ryu Bong-Ha;Kim Jin-Sung;Yoon Sang-Hyub;Ryu Ki-Won;Hong Sang-Sun
    • The Journal of Internal Korean Medicine
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    • v.24 no.2
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    • pp.290-299
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    • 2003
  • Background : Nowadays many researches about it s cure are going on world widely since cancer is one of the most human health threatening diseases. In Chinese and North Korean medicine, Duchesnea india(Audra.) Foche. is practically used to treat many kinds of cancer, but in Korea it is rarely used. So, we need to scientifically identify anti-tumor effects of Duchesnea india(Audra.) Foche. Objective : We are aimed to identify anti-tumor effects of Duchesnea india(Audra.) Foche. on the stomach cancer cells through molecular biologic methods. Material & Methods : We used AGS as stomach cancer cells from American Type Culture Collection. We added the boiled extract of Duchesnea india(Audra.) Foche. $5{\mu}l$(Sample I), $10{\mu}l$(Sample II) to cultural media(ml)for 0,6, 12, 24, 48 hours. We measured the killing effect on stomach cancer cells through Tryphan blue exclusion test and the suppressive effect on viability of stomach cancer cells via MTT assay. the quantitative RT-PCR was used to examine their effect on the revelation of Bcl-2, Bcl-XL, and Bax, which are genes related to apoptosis. We measured change of mitochondria membrane permeability and membrane potential via flow cytometry. Result : 1. The killing effect on stomach cancer cells showed that each test groups killed more stomach cancer cells than the control group with a time(6 hours later) and density dependent manner, which was statistical significance. 2. The suppressive effect on viability of stomach cancer cells showed that each test groups had more suppressive effects on viability of stomach cancer cells than the control group with a time(6 hours later), which was statistical significance. 3. In the test about the revelation of genes related to apoptosis, the revelation of Bcl-2 and Bcl-XL decreased with a density manner which was statistical significance. but the revelation of Bax was not changed with statistical significance. 4. As a result of this test, Duchesnea india(Audra.) Foche. caused apoptosis by decreasing the absorbance of mitochondria with statistical significance. and also induced apoptosis by decreasing the membrane potential of mitochondria. Conclusion : This experiment showed that Duchesnea india(Audra.) Foche. has anti-tumor effect with statistical significance. This is in vitro experiment and basic experiment on Duchesnea india(Audra.) Foche. We hope more progressive researchs on Duchesnea india(Audra.) Foche. will go on and its anti-tumor effects will be more practically identified.

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The Effect of Chronic Alcohol Administration to Alteration of Liver, Kidney and Stomach in Mouse (장기 알콜투여가 생쥐의 간 및 신장, 위장조직 손상에 미치는 영향)

  • Kim, Jin-Taek;Kim, Dong-Hoan;Ahn, Sang-Hyun
    • The Journal of Dong Guk Oriental Medicine
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    • v.3
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    • pp.163-169
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    • 1994
  • Alcohol is a major risk factor for several diseases and excessive, long-term alcohol consumption are caues physical alteration-fatty liver, hepatitis, cirrhosis, breaking down, Wernicke-karsakoff's syndrome, weight loss, and poor immunity-in virtually all organ and tissue. This study was observed that liver, kidney, and stomach were altered in mouse by the effect of chronic alcohol administration. The mouse were sacrificed to obtain the tissue after mouse were orally injected with 25 % ethanol $18m{\ell}/kg/day$ for 120days. The tissue were stained by hematoxylin and eosin and then observed by light microscope. The results of this study were as follows : 1. The congestion was appeared in liver after 120days alcohol admistration. 2. The destruction of glomerulus were increased and the parietal cell of Bowman's capsule were swelled such as cuboidal cell after 120days alcohol administration. The congestion was appeared in alcohol administrated group. 3. The mucosa and gastric pit were destructed and the ulceration was appeared in stomach after 120days administration. The parietal cells and chief cells were damaged. Above results were shown that the tissue were damaged by chronic alcohol administration.

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Treatment of Skin Diseases in Hyungsang Medicine (피부병의 형상의학적 치료)

  • Suk Min He;Hwang Won Duek;Jung Haeng Gyu;Lee Yong Tae
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.18 no.3
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    • pp.646-669
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    • 2004
  • By treating skin diseases with Hyungsang medicine and reviewing the clinical cases of them through classifying skin diseases into general care and into Hyungsang medical care, the writer came to the conclusion as followings. The skin is a house of Kyungnak, and it' s a place which Ki comes in and out, which human body controls conditions of his physiological function and which doctors can make a diagnosis from seeing it. The skin is subject to lung and large intestine in the point of organ, but in the point of movement, to spleen and stomach. Skin diseases come from unbalance of Ki and Hyul, mostly from fever in blood and also from Dam, Wind, Dampness and Dryness because of including fire. Generally skin diseases are treated according to classifying into distinctive symptoms, region, cause or time being occurred, and concomitant symptoms. After being divided into man and woman, age and youth, fatness and leanness, Jung Ki Shin Hyul type, visceral figures, Yukkyung shapes on Hyungsang medicine method, the remedy of skin diseases which is combined common meditation with Hyungsang medical method is efficacious. In distinguishing into man and woman, age and youth, man gets sick mainly by drinking liquor and exhausting Jung, woman is taken ill generally by indigestion and Damwha, especially by drinking liquor. Young child gets ill mostly from inherent weakness, but in many cases he is occurred by disturbed digestion, so he must be taken care of ingesting food. The aged becomes ill from weakening, so he must be treated according to reasons of diseases. To fatness and leanness, skin diseases are showed symptoms by weakened Yang, insufficient Yin or excess fever on the theory of upper and lower parts, by unbalance of Ki and Hyul on the theory of left and right, by Dryness and Dampness on the theory of front and rear and by insufficiency of vitality and combined fever on the theory of inside and outside. Therefore doctors must cure the symptoms according to the theory of upper and lower, left and right, front and rear and inside and outside. In type of Jung Ki Shin Hyul, the balances between Jung-Hyul and Shin-Ki are important points. Concretely Jung type comes to easily shortage of Jung or gathering abnormally Dampness and Dam, Ki type is easy to make a mass with Ki or to be deficient of Ki, Shin type comes to press seven emotions togather or to be insufficient of Yin and fever inside, and Hyul type is inclined to be deficient of Hyul and to become feverish or to be deficient of Ki. Therefore on the ground of the above reasons skin diseases come into existence. Inclusively in Jung-Hyul type , Ki must be moved on the base of full Jung-Hyul, so Wukmijiwhangtang or Samultang is prescribed basically. In Shin-Ki type , Jung-Hyul is saved on the base of moving Ki, so Hyangsosan or Yijintang is the proper prescription. Considering the visceral figures, doctors judge for diagnosis and remedy by putting together the elements, that is, great and small sizes of a set of features (eye, ear, mouth, nose), color and temper. The yukkyung types are classified according to many or few of Ki-Hyul, and then skin diseases appear by being inclined toward one side between Ki and hyul, or among the six atmospheric elements(wind, cold, heat, dampness, dryness, and fire). Especially because Yangmyung type is full of much Ki and Hyul, and also has much fever in stomach, he gets skin symptoms frequently. So his prescription is based on taking off fever in stomach, and also he must be careful about regimen certainly.

The research into the life and medical philosophy of Na Cheon-ik (나천익(羅天益)의 생애(生涯)와 의학사상(醫學思想)에 관(關)한 연구(硏究))

  • Kim, Byung-kuk;Yun, Chang-yeol
    • The Journal of Korean Medical History
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    • v.13 no.1
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    • pp.33-45
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    • 2000
  • Through this research author discovered the fact that Na Cheon-ik inherited the 'Bi Wi Nai Sang Seol' of Lee Ko, which bases spleen and stomach as the fundamentals of our body, and stated the importance of rise of the spleen ki. He also stated the ways in which spleen and stomach could be damaged and in doing so, he made sub-divisions into 'Sik Sang Bi Wi Ron' and 'Eum Sang Bi Wi Ron' to explain how the diseases and treatment could be different. As well, he presented the importance of the relationship between the five visceras and the dialectics of triple energizer.

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Examination of the Diseases of Chosun Dynasty's InJo (조선시대(朝鮮時代) 인조(仁祖)의 질병(疾病)에 관한 고찰(考察))

  • Kim, Hun
    • The Journal of Korean Medical History
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    • v.18 no.2
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    • pp.15-37
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    • 2005
  • In this paper, the overall contents of InJo's disease centering on the records from Chosun Dynasty's Official Records were examined. As a result, it was elucidated that the fundamental cause had lied in internal injuries of the Spleen and Stomach. The reason behind the constant change from fever to chills that agonized InJo the most lied not so much in external hazards as much in the injuries of the Spleen and Stomach. The treatment for InJo focused more on acupuncture methods than herbal medicine, which is thought to be characteristic of mid-Chosun Dynasty starting from the times of prior king SunJo or GwangHaeGun.

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Hepatic extraskeletal osteosarcoma with systemic metastasis in a dog

  • Johnson, Crystal;Kim, Yongbaek
    • Korean Journal of Veterinary Research
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    • v.53 no.1
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    • pp.61-64
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    • 2013
  • A ten-year-old dog was presented with pancreatitis and increased hepatic enzymes. On necropsy a large firm mass was observed in the liver extending to the gall bladder. Smaller masses with similar texture were found in multiple organs including lung, stomach, pancreas, lymph nodes, omentum, and mesentery. Neoplastic cells were spindle shaped with prominent osteoid production and occasional trabeculae of woven bone. Tumor cell emboli were observed in the blood vessels and lymphatics of the omentum and stomach. Hepatic osteosarcoma with systemic metastasis is very rare and may serve to broaden the diagnostic spectrum of hepatic and pancreatic diseases in dogs.

Contraction-related frequency harmonics in human electrogastrography (위전도에서의 위의 수축과 관련된 주파수 성분에 관한 연구)

  • Han, W.T.;Kim, I.Y.;Kim, W.K.
    • Proceedings of the KOSOMBE Conference
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    • v.1996 no.05
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    • pp.3-5
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    • 1996
  • Electrogastrography(EGG) is the technique by which gastric myoelectrical activity is recorded noninvasively, from electrodes on the abdominal skin. This gastric myoelectrical activity consists of two type signals : 1) slow wave, which is gastric basal rhyemic activity and is not closely related to gastric contraction 2) spike wave, which is generated only during contraction of the stomach. Despite many attempts made over the decades, analysis of surface EGG has not led to identification of the spike wave (gastric contraction) that would help the clinician to diagnose functional or organic diseases of the stomach. In this paper, we propose a feasible methods to detect gastric contraction by frequency-domain signal analysis of surface ECG signal. Synchronous measurement of gastric pressure by the antropyloric manometry with surface EGG established feasibility of this method.

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Accuracy of Endoscopic Ultrasonography for Determination of Tumor Invasion Depth in Gastric Cancer

  • Razavi, Seyed Mohsen;Khodadost, Mahmoud;Sohrabi, Masoudreza;Keshavarzi, Azam;Zamani, Farhad;Rakhshani, Naser;Ameli, Mitra;Sadeghi, Reza;Hatami, Khadijeh;Ajdarkosh, Hossein;Golmahi, Zeynab;Ranjbaran, Mehdi
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.8
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    • pp.3141-3145
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    • 2015
  • Background: Gastric cancer (GC) is one the common lethal cancers in Iran. Detection of GC in the early stages would assesses to improve the survival of patients. In this study, we attempt to evaluate the accuracy of EUS in detection depth of invasion of GC among Iranian Patients. Materials and Methods: This study is a retrospective study of patients with pathologically confirmed GC. They underwent EUS before initiating the treatment. The accuracy of EUS and agreement between the two methods was evaluated by comparing pre treatment EUS finding with post operative histopathological results. Results: The overall accuracy of EUS for T and N staging was 67.9% and 75.47, respectively. Underestimation and overestimation was seen in 22 (14.2%) and 40 (25.6%) respectively. The EUS was more accurate in large tumors and the tumors located in the middle and lower parts of the stomach. The EUS was more sensitive in T3 staging. The values of weighted Kappa from the T and N staging were 0.53 and 0.66, respectively. Conclusions: EUS is a useful modality for evaluating the depth of invasion of GC. The accuracy of EUS was higher if the tumor was located in the lower parts of the stomach and the size of the tumor was more than 3 cm. Therefore, judgments made upon other criteria evaluated in this study need to be reconsidered.