• Title/Summary/Keyword: Stings of Gleditsia sinensis

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Antioxidant Activity and Alpha-Glucosidase Inhibitory Activity of Stings of Gleditsia sinensis Extracts (조각자 추출물의 항산화 활성 및 alpha-glucosidase 저해 활성)

  • Lee, Jeung-Min;Park, Jae-Hee;Chu, Won-Mi;Yoon, Yi-Mook;Park, Eun-Ju;Park, Hae-Ryong
    • Journal of Life Science
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    • v.21 no.1
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    • pp.62-67
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    • 2011
  • This study was performed to investigate the physiological activities of stings of Gleditsia sinensis extracts. Antioxidant activity was evaluated by measuring total phenolic contents (TPC), comet assay, and 2.2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity (RSA). Anti-diabetic activity was measured by inhibition activities on $\alpha$-glucosidase. Stings of Gleditsia sinensis extracts were prepared by extracting them with methanol and ethanol. The methanolic extracts showed the highest phenol content (1.12 g/100 g gallic acid equivalents). The $\alpha$-glucosidase inhibitory activity of methanol extracts were 17.9% higher, and that of ethanol extracts were 10.3% higher at a concentration of 1 mg/ml. These results indicate that stings of Gleditsia sinensis might be potential candidates as antioxidant and anti-diabetic agents.