• Journal of Biomedical Engineering Research
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• v.29 no.5
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• pp.408-413
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• 2008

Human body has a complete left and right symmetry structure, and the left and right balance by Yin and Yang. When the balance is broken, the left and right Meridian becomes abnormal condition. Acupuncture is a kind of therapy to recover from energy unbalance of the left and right Meridian to a new balance condition. In the study, we observed the electric potential along the stomach meridian (ST) in order to verify the energy consensus phenomenon by transportation of bio-energy between operator and subject during acupuncture. The acupuncture effects on opposite meridian site were investigated by comparing the electric potentials between the right and left ST sites. Meridian electrical potentials (MEPs) between operator and subject were simultaneously generated during the acupuncture and the polarity of MEPs was opposite. The results might imply the bio-energy transportation between operator and subject. In addition, we observed three different patterns of MEPs on both ST sites which might represent the condition of the related meridians because meridians in the body are organically interconnected.

• Journal of Acupuncture Research
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• v.21 no.2
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• pp.57-71
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• 2004

Objective : Physiological evidence regarding acupuncture's effect in human patients is not yet well established, despite considerable evidence for its therapeutic efficacy. Besides target or disease specificity of acupuncture, acupuncture analgesia (AA) appears to be another large subclass that poses many questions, such as whether there is point specificity with respect to which acupoint is most effective for a particular condition. Methods : We observed brain activation with functional magnetic resonance imaging (fMRI) using a set of stimuli that consist of pain, pain following Meridian acupuncture, and pain following Sham acupuncture. Results : Among the new observations, the most interesting fact is that data sets of both Meridian acupuncture and Sham acupuncture show decreased activation of the same brain areas related to the pain processing signals. Present functional MRI study demonstrate two important biological observations that could elucidate AA mechanism in human participants: the effects of acupuncture occur through mediation of the higher brain areas. Sham acupuncture stimulation appears to be almost as effective as traditional Meridian acupoint stimulation, suggesting that acupuncture is not entirely point specific. Decreased activation in the limbic paleo cortical areas appears to be the probable neurological manifestation of AA and strongly implies that acupuncture stimulation inhibits the transmission of ascending pain signals to the higher cortical areas by the previously known descending pain inhibitory circuit. Conclusion : We, therefore, a hypothesized that this pain inhibitory circuit is initiated and mediated via the broad sense Hypothalamus Pituitary Adrenal (BS HPA) axis in conjunction to the "sensory stimulation."

• Journal of Embryo Transfer
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• v.9 no.2
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• pp.145-152
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• 1994

The suitable electric stimulation is essential for activation and fusion of oocytes before or after nuclear transplantation The present study was undertaken to determine the optirnal condition for the parthenogenetic activation of in vitro rnatured(IVM) bovine oocytes by electric stimulation. Different direct current(DC) electric voltage of 1.0, 1.5 and 2.0 kV/cm and pulse duration of 30, 60 and 120 $\mu$sec were applied to the JVM nocytes in 0.3 M mannitol solution containing each 100 $\mu$M CaCl$_2$ and MgCl$_2$. IVM occytes at 24, 28 and 32 hours Post-maturation(hpm) were also electrically stimulated at 1.5 kV /cm, for 60 $\mu$ sec. The stimulated nocytes were then co-cultured in TCM-199 solution containing 10% fetal calf serum with bovine oviductal epithelial cells for 7~9 days in a 5% $CO_2$ incubator at 39$^{\circ}C$ ~ Their activation and in vitro development to morula and blastocyst were assessed under an inverted microscope. The higher activation rates 62.8 and 63.4% and in vitro de- velopment rates to morula and blastocyst 5.1 and 10.9% were shown in the oocytes stimulated at the voltage of 1.0 and 1.5 kV/cm than 2.0 kV/cm, respectively. No signifi- cantly(P<0.05) different activation rate was shown in JVM oocytes stimulated for 30, 60 and 120 $\mu$sec, but developmental rates to morula and blastocyst was significantly(P<0.05) higher in the oocytes stimulated for 30 $\mu$sec(6~3%) and 60 $\mu$sec(10~0%) than 120 $\mu$sec(0~ 0%). The aged oocytes at 28 and 30 hpm showed significantly(P<0.05) higher activation rates(72~7 and 79.7%) than the oocytes at 24 hpm(50~9%)~ Also, their developmental rates to morula and blastocyst were significantly(P<0.05) higher in the nocytes at 28(14.3%) and 32 hpm(15.9%) than 24 hpm(3.6%). From these results, it can be suggested that the optimal electric stimulation for IVM bovine occytes is a DC voltage between 1.0 and 1.5 kV/cm, pulse duration of 30 or 60 $\mu$sec, and the optimal age of IVM oocytes for electric activation is at 32 hpm.

• Physical Therapy Rehabilitation Science
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• v.13 no.2
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• pp.152-162
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• 2024

Objective: This study was conducted to analyze the effect of wearable Electromyography-controlled functional electrical stimulation (EMG-controlled FES) System on Gait Function and cardiopulmonary metabolic efficiency during walking in older adults. Design: Cross-section study Methods: Total 22 older adult participants suitable to selection criteria of this study participated in this study. The EMG-controlled FES System, which functions as a wearable physical activity assist FES system was used. All participations performed randomly assigned two conditions (Non-FES assist [NFA], FES assist [FA]) of walking. In all conditions, spatio-temporal parameters and kinematics and kinetics parameters during walking was collected via 3D motion capture system and 6 minutes walking test (6MWT) and metabolic cost during walking and stairs climbing was collected via a portable metabolic device (COSMED K5, COSMED Srl, Roma, Italy). Results: In Spatio-temporal parameters aspects, The EMG-controlled FES system significantly improved gait functions measurements of older adults with sarcopenia at walking in comparison to the NFA condition (P<0.05). Hip, knee and ankle joint range of motion increased at walking in FA condition compared to the NFA condition (P<0.05). In the FA condition, moment and ground reaction force was changed like normal gait during walking of older adults in comparison to the NFA condition (P<0.05). The EMG-controlled FES system significantly reduced net cardiopulmonary metabolic energy cost, net energy expenditure measurement at stairs climbing (P<0.05). Conclusions: This study demonstrated that EMG-controlled FES is a potentially useful gait-assist system for improving gait function by making joint range of motion and moment properly.

• Korean Journal of Acupuncture
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• v.21 no.4
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• pp.1-19
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• 2004

Objectives : To understanding biological mechanism of acupuncture therapy, we have proposed a hypothesis. First of all, there exists electric property in meridian and meridian point. Second of all, energy flowing in meridian is related with electric property. Third of all, there is electronic interaction between the operator who performs acupuncture therapy and the receiver who is given acupuncture therapy. Forth of all, acupuncture effects may depend on the electric capacity which is transferred between the operator and the receiver via acupuncture needle. Methods : Under the hypothesis, we studied the effects of electric change in $ST_{37}(+)\;and\;ST_{39}(-)$ generated by Tanchim (彈鍼) manipulation which was stimulated at $ST_{36}$ point. And compared with data on the changes of electric change from the hand of the operator during acupuncture stimulation. Electric charge induced via acupuncture needle from the operator may be important factor that causes the changes of electric change in meridian and acupoint in the receiver. Therefore we investigated the changes of electric charge induced by the operator using Maclab 400 by the following methods. The one was in stable electric circle condition and the other was in unstable electric circle condition. Results : In this experiments, the changes of electric change from the stimulation type of Tanchim manipulation performed in our lab condition in acupuncture therapy was induced at least three factor, one was the difference of bio-potentials between the operator and the receiver of acupuncture therapy, another was the depth of acupuncture insertion from the skin of the receiver, the other was an electromyogram of the receiver. Conclusion : The data imply that the first factor should make a capacitance current when the operator touched the acupuncture needle which was inserted in the receiver. Therefore, the results suggest that capacitance currents stimulus in electronic view may be important factor in acupuncture therapy between the operator and the receiver of acupuncture therapy.

• The Journal of Korean Medicine
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• v.27 no.1 s.65
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• pp.146-154
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• 2006

Objectives : Siguan points (LI4, LR3) have been most frequently applied for various diseases, especially different digestive disorders such as constipation, abdominal pain or various intestinal inflammatory diseases. The fact that gastrointestina movement is closely connected with physiologic functions or pathologic process of alimentary canal led us to ask the question if Siguan points affects on intestinal motility. Design: To investigate the effect of Siguan acupuncture on the intestinal movement in both physiologic and pathologic conditions, we divided the experimental animals into 12 groups. Six groups were pre-treated with loperamide (0.5 mg/kg, sc) or scoploamine (0.5 mg/kg, sc) to suppress the intestinal movement and another three groups were pretreated with carbachol (0.5 mg/kg, po) to activate it, whereas the rest three groups didn't receive any pretreatment to be kept in the physiological condition. After the administration with charcoal meal, mice were acupunctured bilaterally on sham point or Siguan points as the manner of tap-stimulation, with the exception of no acupuncture groups. Methods : Mice were scarified in twenty minutes after the administration of charcoal to measure the distance of charcoal passage from stomach-duodenal junction. The effect on intestinal movement was presented by calculating the relative distance where charcoal arrived to total length of small intestine. Results : In physiological state, charcoal meal passed around 53%, and there was no significant difference between Siguan points and sham points groups. On the other hand. Siguan points-sitimulation significantly ameliorated loperamide or scoplolamine-induced suppressed travel rate of 17.3 % and 18.6% in sham point into 26% and 26.3% respectively (p<0.05). In carbachol-induced accelerated condition, Siguan points-stimulation didn't affect intestinal motility comparing to sham point group passed about 97.6%. Conclusions : These results postulate that acupuncture at Siguan points have a therapeutic effect by restoring cholinergic activity on pathogenically suppressed intestinal peristalsis, but does not affect the gastrointestinal motility in the normal or accelerated condition.

• Journal of Biomedical Engineering Research
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• v.16 no.4
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• pp.507-516
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• 1995

The nonstationary identifier in the DCT domain is suggested in this study for the identification of AR parameters of above-lesion upper-trunk electromyographic (EMG) signals as a means of developing a reliable real time signal to control functional electrical stimulation (FES) in paraplegics to enable primitive walking. As paraplegic shifts his posture from one attitude to another, there is transition period where the signal is clearly nonstationary. Also as muscle fatigues, nonstationarities become more prevalent even during stable postures. So, it requires a develpment of time varying nonstationary EMG signal identifier. In this paper, time varying nonstationary EMG signals are transformed into DCT domain and the transformed EMG signals are modeled and analyzed in the transform domain. In the DCT domain, we verified reduction of condition number and increment of the smallest eigenvalue of input correlation matrix that influences numerical properties and mean square error were compared with SLS algorithm, and the proposed algorithm is implemented using IMS T-805 parallel processing computer for real time application.

• Korean Journal of Acupuncture
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• v.22 no.4
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• pp.9-27
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• 2005

Objective : hypothesis. First of all, there exists electric property in meridian and meridian point. Second of all, energy flowing in meridian is related with electric property. Third of all, there is electronic interaction between the operator who performs acupuncture therapy and the receiver who is given acupuncture therapy. Forth of all, acupuncture effects may depend on the electric capacity which is transferred between the operator and the receiver via acupuncture needle. Methods : Under the hypothesis, I studied the effects of electric charge in ST37(+) and ST39(-) generated by Apchim (押鍼) manipulation which was stimulated at ST36 point. And compared with data on the changes of electric charge from the hand of the operator during acupuncture stimulation. Electric charge induced via acupuncture needle from the operator may be important factor that causes the changes of electric charge in meridian and acupoint in the receiver. Therefore we investigated the changes of electric charge induced by the operator using Maclab 400 by the following methods. The one was in stable electric circle condition and the other was in unstable electric circle condition. In this experiments, the changes of electric charge from the stimulation type of Apchim manipulation performed in our lab condition in acupuncture therapy was induced at least three factor, one was the difference of bio-potentials between the operator and the receiver of acupuncture therapy, another was the depth of acupuncture insertion from the skin of the receiver the other was an electromyogram of the receiver. Results :The data imply that the first factor should make a capacitance current when the operator touched the acupuncture needle which was inserted in the receiver. Therefore, the results suggest that capacitance currents stimulus in electronic view may be important factor in acupuncture therapy between the operator and the receiver of acupuncture therapy.

• Textile Coloration and Finishing
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• v.23 no.3
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• pp.219-226
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• 2011

Recently, study of functional clothing for vital sensing is focused on improving conductivity and decreasing resistance, in order to enhance the electrocardiogram(ECG) sensing accuracy and obtained stable environmental durability on operation condition. In this study, four ECG fabrics that having different componnt yarns and weaving structures were produced to analyze their environmental durabilities and electric properties under general operation conditions including different physical and chemical stimulation. For outstanding electric properties and physical properties, the optimized ECG sensing fabric should consist of a fabric of 2 up 3 down twill structure containing 210de silver-coated conductive yarns and polyester yarn in warp and weft directions respectively. The selected fabric has $0.11{\Omega}$ which is relative lower resistance than otherwisely produced fabrics under ECG measurement condition. And it has 7% stable resistance changes under 25% strain and repeated strain.

• Journal of Korean Ophthalmic Optics Society
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• v.5 no.2
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• pp.5-9
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• 2000

The visual evoked potential was electrophysiological method for the identify of the EEG response on visual cortex. This test was objective test method on the eye function. This study was used the visual evoked potential for the objective color test. The subjects was a normal color function in Korean adults. The test condition was performed on the differens distance and illumination. According to convergence condition of color vision target. On the appearance of EEG wave of visual stimulation on visual cortex. The most EEG wave style was delta wave, and the next amount wave form was beta wave and theta wave, and the least EEG wave form was alpha wave. The histogram of amplitude of EEG wave form was almost non-Gaussian shape, and the phase diagram of amplitude was almost all linear shape. On the kinds of color vision target, the frequency of EEG wave style appeared a similar results.