• Title/Summary/Keyword: Stem effect

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Effect of Cake Improver on Antioxidant Activity and Properties Characteristics of Pound Cakes Prepare using Broccoli Stem Powder (브로콜리 줄기 분말을 혼합한 파운드 케익의 항산화 활성과 품질 특성에 미치는 영향)

  • Oh, Jae-Bok;Lee, Hye-Jeong
    • The Korean Journal of Food And Nutrition
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    • v.24 no.4
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    • pp.567-576
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    • 2011
  • A study was undertaken to examine the antioxidative activity and the quality attributes of broccoli stem powder pound cakes. Broccoli stem powder was added to the batter at a ratio of 5, 10 and 15% respectively. The antioxidant activity was estimated by DPPH free radical scavenging activity, the total phenolic compounds content and flavonoid content in Broccoli stem powder and pounds cakes. Antioxidative activity was highly correlated with the total phenolic and total flavonoids contents of broccoli stem pound cakes respectively($r$=0.937, $r$=0.981). The effect of cake improver on quality characteristics of cake broccoli stem powder and pound cakes were estimated in terms of the specific load volume, hardness, hunter value of crumb and crust and sensory quality of cakes. The specific volume were increased significantly with increasing substitution level of cake improver and broccoli stem powder($p$ <0.01). The lightness were significantly decreased with increases in broccoli stem powder of pound cake crust and crumb($p$ <0.01, $p$ <0.01). The hardness, chewiness and gumminess and cohesiveness were tended to reduce in both of powder. The consumer acceptability score for 5~10% broccoli stem pound cakes ranked significantly($p$ <0.01) higher than those of the other groups in taste, flavor and overall preference. This results showed that cake improver & broccoli stem powder are a good ingredient to increase consumer acceptability and the healthy.

Protective Effect of NACA on Periodontal Stem Cell (NACA 처리에 따른 치주줄기세포 사멸 억제 효과)

  • Lee, Kyunghee
    • Journal of The Korean Society of Integrative Medicine
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    • v.8 no.3
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    • pp.53-62
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    • 2020
  • Purpose :Periodontal ligament stem cells maintain tissue homeostasis in periodontal ligament. The purpose of this study was to determine the characteristics of periodontal ligament stem cells isolated from premolar teeth and observe protective effects against oxidative damage caused by Triethylene glycol dimethacrylate (TEGDMA) following treatment with N-acetylsysteine amide (NACA) drug known as enzymatic antioxidants. Methods : Primary periodontal ligament stem cell (PDSC) culture was performed from simply extracted human premolar of orthodontic patients. The characteristics of the primary cultured PDSCs was analyzed using the FACS system. PDSCs was incubated with TEGDMA and NACA. The cell proliferation and survival was determined using WST-1 assay. Collected data were analyzed using SPSS Window 20. Results : Primary cultured PDSCs grow on the floor and develop rapidly in a cluster form from up to 14 days. The morphology of PDSCs showed the spindle-shaped cells and grew directionally. FACS analysis, In addition, positive expression of visible cells were observed in mesenchymal stem cell biomarkers. PDLSCs cell viability was significantly decreased at high concentration in both 3 and 6 hours after TEGDMA treatment. We observed a decrease in the number of cells as well as a morphological change of PDLSCs. Antioxidative effect was notable since the death of PDLSC death was significantly inhibited compared to the control group at 24 and 48 hours after NACA treatment. Conclusion : Therefore, based on the results of this study, further research should be encouraged considering the development of clinical treatment methods using various antioxidants as well as regenerative engineering techniques utilizing periodontal ligament stem cells.

Biocontrol Effect of Gliocladium virens G1 and Soil Amendment on Astragal Stem Rot Caused by Rhizoctonia solani

  • Chung, Bong-Koo;Yun, Kyung-Ho
    • Mycobiology
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    • v.28 no.4
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    • pp.180-184
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    • 2000
  • In order to find an environment-friendly method to suppress astragal stem rot caused by the isolates of Rhizoctonia solani AG 1 and AG 4, we tested an antagonistic fungus Gliocladium virens G1 was evaluated as a biocontrol agent and estimated inorganic compounds and organic materials were tested for their effect of the disease suppression. G. virens G1 effectively inhibited mycelial growth in a dual culture and caused mycelial lysis in the culture filtrate. No adverse effect was observed when examined for seed germination and seedling growth. Promoted seedling growth was observed with the seed treatment. Seeds of astragal plant were germinated higher in the sterile soil than the natural soil. Of 14 inorganics tested, alum, aluminum sulfate and calcium oxide significantly suppressed the mycelial growth and sclerotial germination. Milled pine bark and oak sawdust also suppressed the mycelial growth. Soil amended with 1% of G. virens G1 composted with pine bark (w/v) significantly controlled astragal stem rot in the glasshouse experiments.

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Nonmyeloablative Stem Cell Transplantation (비골수제거성 조혈모세포이식)

  • Hyun, Myung-Soo
    • Journal of Yeungnam Medical Science
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    • v.19 no.1
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    • pp.11-27
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    • 2002
  • Allogenic hematopoietic stem cell transplantation is one of the effective therapy for several hematologic malignancies. Transplantation preparative regimen is designed to eradicate the patient's underlying disease and immunosuppress the patient adequately to prevent rejection of donor's hematopoietic stem cells. So, conventional myeloablative preparative regimens with high-dose chemotherapy or radiotherapy are related to high rate of morbidity and mortality. However, It has become clear that the high-dose therapy dose not eradicate the malignancy in some patients, and that the therapeutic benefit of allogenic transplantation is largely related to graft-versus-leukemia/graft-versus-tumor (GVL/GVT) effect. An new approach is to utilize less toxic, nonmyeloablative preparative regimens to achieve engraftment and allow GVL/GVT effects to develop. This strategy reduces the risk of treatment-related mortality and allows transplantation for elderly and those with comorbidities that preclude high-dose chemoradiotherapy.

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Effect of Photobiomodulation on the Mesenchymal Stem Cells

  • Yoo, Shin Hyuk
    • Medical Lasers
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    • v.9 no.2
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    • pp.119-125
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    • 2020
  • Photobiomodulation forms the basis of photomedicine and is defined as the effect of coherent or non-coherent light sources, such as low-level lasers and light-emitting diodes, on cells and tissues. This treatment technique affects cell functions, proliferation, and migration, and plays an important role in tissue regeneration. Mesenchymal stem cells (MSCs) are known to be beneficial for tissue regeneration, and the combination of stem cell therapy and laser therapy appears to positively affect treatment outcomes. In general, a low-power laser has a positive effect on MSCs, thereby facilitating improvements in different disease models. This study elucidates the mechanisms and effects of low-power laser irradiation on the proliferation, migration, and differentiation of various MSCs that have been examined in different studies.

A Study for the Improvement Method of Flexible Wedge Gate Valve Operation Capability (Flexible Wedge Gate 밸브의 운전 성능향상 방안에 관한 연구)

  • Kim, Dae-Woong;Lee, Do-Hwan;Kang, Sin-Chul;Kim, In-Whan;Park, Sung-Keun
    • Proceedings of the KSME Conference
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    • 2001.06a
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    • pp.644-651
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    • 2001
  • The purpose of this study is to develop the improvement method of MOV(Motor Operated Valve) operability without major modification or change of MOV which needs a great expense and manpower. We studied valve stem lubrication, stem packing thrust and actuator control switch which could give an major effect to MOV operability, and found the some consequences. First, the stem/stem-nut friction coefficient and stem factor is significantly effected by stem lubrication state. Second, the measured packing thrust value is appeared higer than the design value for tested valves and the preparation of optimal value selection criteria is needed. Finally, optimization of MOV control switch is another major factor for MOV operability and structual integrity.

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Life Cycle Analysis of Stem Cell Technology Based on Diffusion Model : Focused on the Research Stage (확산 모형을 이용한 줄기 세포 기술의 수명 주기 분석 : 연구 단계를 중심으로)

  • Jang, In-young;Hong, Jungsik;Kim, Taegu
    • Journal of Korean Institute of Industrial Engineers
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    • v.41 no.5
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    • pp.488-498
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    • 2015
  • Research on stem cells can be divided into three categories : pluripotent stem cell, adult stem cell, and induced pluripotent stem cell. Technology life cycle (TLC) on research stage is analyzed for the three stem cell categories based on diffusion model. Three diffusion models-logistic, Bass, and Bass model with integration constant (BMIC)-are applied to the number of articles related to each stem cell category in SCOPUS lists. Two different parameter estimation methods is used for each of logistic and Bass model. Results show that (1) the current year, 2015, lies in growth period at pluripotent stem cell and adult stem cell, and lies in growth period or maturity period at induced pluripotent stem cell. (2) Model fitness is the highest at BMIC model. (3) Imitation effect works best at the research area of induced pluripotent stem cell.

Stress analysis of the effect of debonding of cement-femoral stem interface to the bone-cement interface -A three-dimensional Finite Element Analysis- (시멘트-대퇴Stem 경계면 해리가 골-시멘트 경계면에 미치는 응력 분석 -3차원 비선형 Finite Element Analysis-)

  • Kim, S.K.
    • Proceedings of the KOSOMBE Conference
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    • v.1996 no.11
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    • pp.337-346
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    • 1996
  • Debonding of cement-femoral stem interface has been suggested as a initial focus of loosening mechanism in many previous studies of cemented total hip replacement. The purpose of this study was to investigate the effect of debonding of cement-femoral stem interface to the bone-cement interface by using three-dimensional non-liner finite element analysis. Three cases of partial debonded, full debonded, full bonded cement-bone interface were modelled with partial bonding of distal 70mm from the tip of femoral stem. Each situation was studied under loading stimulating one-leg stanced gait of 68kg patient. The results showed that under partial and full debonded cement-stem interface condition the peak von Mises stress(3.1 MPa) were observed at the cement of bone-cement interface just under the calcar of proximal medial of femur, and sudden high peak stresses(3.5MPa) were developed at the distal tip of femoral stem at the lateral bone-cement interface in all 3 cases of bonding. The stresses were transfered very little to the cement of upper lateral bone-cement interface in partial and full debonded cases. Thus, once partial or full debonded cement-femoral stem interface occured, 3 times higher stress concentration were developed on the cement of proximal medial bone-cement interface than full bonded interface, and these could cause loosening of cemented total hip replacement. Clinically, preservation of more rigid cement-femoral stem interface may be important factor to prevent loosening of femoral stem.

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