• 한국지진공학회:학술대회논문집
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• 한국지진공학회 1999년도 추계 학술발표회 논문집 Proceedings of EESK Conference-Fall
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• pp.64-71
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• 1999

Seismicity of the Korean Peninsula shows intraplate seismicity that has irregular pattern in both time and space. Seismic data of the Korean peninsula consists of historical earthquakes and instrumental earthquakes. In this study we devide these data into complete part and incomplete part and considering earthquake size uncertainty estimate seismic hazard parameters - activity rate λ, b value of Gutenberg-Richter relation and maximum possible earthquake IMAX by statistical method in each major tectonic provinces. These estimated values are expected to be important input parameters in probabilistic seismic hazard analysis and evaluation of design earthquake.

• Communications for Statistical Applications and Methods
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• 제25권3호
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• pp.321-328
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• 2018

In clinical trials with repeated measurements, the time-averaged difference (TAD) may provide a more powerful evaluation of treatment efficacy than the rate of changes over time when the treatment effect has rapid onset and repeated measurements continue across an extended period after a maximum effect is achieved (Overall and Doyle, Controlled Clinical Trials, 15, 100-123, 1994). The sample size formula has been investigated by many researchers for the evaluation of TAD in two treatment groups. For the evaluation of TAD in multi-arm trials, Zhang and Ahn (Computational Statistics & Data Analysis, 58, 283-291, 2013) and Lou et al. (Communications in Statistics-Theory and Methods, 46, 11204-11213, 2017b) developed the sample size formulas for continuous outcomes and count outcomes, respectively. In this paper, we derive a sample size formula to evaluate the TAD of the repeated binary outcomes in multi-arm trials using the generalized estimating equation approach. This proposed sample size formula accounts for various correlation structures and missing patterns (including a mixture of independent missing and monotone missing patterns) that are frequently encountered by practitioners in clinical trials. We conduct simulation studies to assess the performance of the proposed sample size formula under a wide range of design parameters. The results show that the empirical powers and the empirical Type I errors are close to nominal levels. We illustrate our proposed method using a clinical trial example.

• 터널과지하공간
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• 제6권3호
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• pp.209-222
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• 1996

Shut-in pressure, reopenting pressure and fracture orientation are very important parameters to be evaluated precisely in in-situ stress measurement by hydraulic fracturing. Graphical methods on pressure-time curves have been conventionally used, even though these are seriously dependent on subjectivity of interpreters. So there have been many demands on new method to objectivity in determining parameters. We have developed integrated hydrofracturing data processing program (HYDFRAC), based on nonlinear regression analysis and can be invoked under the Window graphical user interface. HYDFRAC consiste of three routines, that is shut-in pressure routine, reopening pressure routine, and fracture delineation routine. Each of routines include independent modules according to parameter determination methods. Its application to field tests ensured both objectivity and facility in determining of hydraulic fracturing parameters. Determining shut-in pressures at each pressurization cycles, we adopted the exponential pressure-decay method(EPD method), the bilinear pressure-decay-rate method (PDR method), and the tangent intersection method in order to find the pressurization-cyclic tendency of shut-in pressures. The estimated pressure by PDR method exists in the range of the upper and lower values by EPD method, and lies near to the upper value more than the lower. Being the pressurization cycle increased, the range of upper and lower limits come to be stabilized gradually. By graphical superposition method and bilinear pressure-accumulated volume method, reopening pressures were determined. Vertical and inclined fracture attitudes were determined by applying the directional statistics and sinusoidal curve fitting, respectively. The results of evaluation of hydrofracturing parameters showed that statistical methods could enhance the objectivity better than graphical methods.

• 대한의용생체공학회:의공학회지
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• 제15권3호
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• pp.305-316
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• 1994

All physical data in the real world are nonstationary signals that have the time varying statistical characteristics. Although few algorithms suitable to process the nonstationary signals have ever been suggested, these are treated the nonstationary signals under the assumption that the nonstationary signal is a piece-wise stationary signal. Recently, statistical analysis algorithms for the nonstationary signal have concentrated so much interest. In this paper, nonstationary EMG signals are mapped onto the orthogonal wavelet transform domain so that the eigenvalue spread of its autocorrelation matrix could be more smaller than that in the time domain. Then the model in the wavelet transform domain and an algorithm to estimate the model parameters are suggested. Also, an test signal generated by a white gaussian noise and the EMG signal are identified, and the algorithm performance is considered in the sense of the mean square error and the evaluation parameters.

• Computers and Concrete
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• 제11권6호
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• pp.541-569
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• 2013

There is a wide variety of existing Genetic Algorithms (GA) operators and parameters in the literature. However, there is no unique technique that shows the best performance for different classes of optimization problems. Hence, the evaluation of these operators and parameters, which influence the effectiveness of the search process, must be carried out on a problem basis. This paper presents a comparison for the influence of GA operators and parameters on the performance of the damage identification problem using the finite element model updating method (FEMU). The damage is defined as reduction in bending rigidity of the finite elements of a reinforced concrete beam. A certain damage scenario is adopted and identified using different GA operators by minimizing the differences between experimental and analytical modal parameters. In this study, different selection, crossover and mutation operators are compared with each other based on the reliability, accuracy and efficiency criteria. The exploration and exploitation capabilities of different operators are evaluated. Also a comparison is carried out for the parallel and sequential GAs with different population sizes and the effect of the multiple use of some crossover operators is investigated. The results show that the roulettewheel selection technique together with real valued encoding gives the best results. It is also apparent that the Non-uniform Mutation as well as Parent Centric Normal Crossover can be confidently used in the damage identification problem. Nevertheless the parallel GAs increases both computation speed and the efficiency of the method.

• Communications for Statistical Applications and Methods
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• 제2권2호
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• pp.176-183
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• 1995

Mean opinion score (MOS) method has been used in many areas to quantify opinions of respondents not only in survey research but in evaluating the parameters of population that are not measurable of are technically hard to be measured. Histogram is an important graphical technique because of the role it plays in describing categorical data as well as quantitative. In MOS method, subjective opinions of respondents are quantified by opinion scores and the arithmetic means of opinion scores have been used to describe the interesting population. Since opinion scores are polytomous, the values of arithmetic means have little meanings. In this paper, cumulative percentage curves as a function of the means of opinion scores are derived by combining means of opinion scores and histograms. It is proposed for better interpretation to opinion scores in MOS method, one of subjective evaluation methods.

• 약학회지
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• 제44권4호
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• pp.308-314
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• 2000

Logarithmic transformation of pharmacokinetic parameters is routinely used in bioequivalence studies based on pharmacokinetic and statistical grounds by the United States Food and Drug Administration (FDA), European Committee for Proprietary Medicinal Products (CPMP), and Japanese National Institute of Health and Science (NIHS). Although it has not yet been recommended by the Korea Food and Drug Administration (KFDA), its use is becoming increasingly necessary in order to harmonize with international standards. In the present study, statistical procedures for the analysis of a bioequivalence based on the log transformation and a related SAS procedure were demonstrated in order to aid the understanding and application. The AUC parameters used in this demonstration were taken from the previous bioequivalence study for two aceclofenac tablets, which were performed in a single-dose crossover design. Analysis of variance (ANOVA), statistical power to detect 20% difference between the tablets, minimum detectable difference and confidence intervals were all assessed following log-transformation of the data. Bioequivalence of two aceclofenac tablets was then estimated based on the guideline of FDA. Considering the international effort for harmaonization of guidelines for bioequivalence tests, this approach may require a further evaluation for a future adaptation in the Korea Guidelines of Bioequivalence Tests (KGBT).

• 센서학회지
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• 제13권6호
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• pp.436-445
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• 2004

In this study, a uroflowmetry system was developed to detect a voiding symptom conveniently at home or hospital. A implemented hardware was composed of mechanism and system circuit part, the software was developed to process uroflow data, graph display, extraction of parameter, and evaluation of congregate rate so as to analysis obtaining uroflow data. The following experiment was performed to evaluate an ability of classification and fitness. The curve pattern of uroflow was classified into each symptom. Various parameters were calculated in the curve pattern of each uroflow as follows. The parameters are MFR, AFR, VOL, VT, and FT. A significant difference among parameters was examined by a statistical analysis for extracted parameters between normal and abnormal experimental group. The uroflow data with the various symptom was divided into normal and abnormal group using fuzzy classifier. The result of the fuzzy classification using MFR and AFR was superior by 91.23 % than grouping evaluation including VOL.

• 한국원자력학회:학술대회논문집
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• 한국원자력학회 1996년도 춘계학술발표회논문집(2)
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• pp.429-434
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• 1996

K-REM［1］, which is under development as a realistic evaluation model of large break LOCA, is applied to the analysis of cold leg guillotine break of Ulchin 3&4. Fuel parameters on which statistical analysis of their effects on the peak cladding temperature (PCT) are made and system parameters on which the concept of limiting value approach (LVA) are applied, are determined from the single parameter sensitivity study. 3 parameters of fuel gap conductance, fuel thermal conductivity and power peaking factor are selected as fuel related ones and 4 parameters of axial power shape, reactor power, decay heat and the gas pressure of safety injection tank (SIT) are selected as plant system related ones. Response surface of PCT is generated from the plant calculation results and on which Monte Carlo sampling is made to get plant application uncertainty which is statistically combined with code uncertainty to produce the 95th percentile PCT. From the break spectrum analysis, blowdown PCT of 1350.23 K and reflood PCT of 1195.56 K are obtained for break discharge coefficients of 0.8 and 0.5, respectively.

• Nuclear Engineering and Technology
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• 제34권6호
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• pp.533-544
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• 2002

The neutron induced nuclear data for Mo-95, Tc-99, Ru-101 and Rh-103 was calculated and evaluated in the fast energy region. The energy dependent optical model potential parameters were extracted based on the recent experimental data and applied up to 20 MeV. The s-wave strength function was calculated from the parameters. Spherical optical model, statistical model in equilibrium energy, multistep direct and multistep compound model in pre-equilibrium energy and direct capture model were used in the calculation. The theoretically calculated cross sections were compared with the experimental data and the evaluated files The model- calculated total and capture cross sections were in good agreement with the reference experimental data. The direct capture contribution improved the capture cross sections in pre- equilibrium region. The evaluated cross section results were compiled to ENDF-6 format and will improve the ENDF/B-Vl.