• Title/Summary/Keyword: State Delay

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Performance Evaluation of Output Queueing ATM Switch with Finite Buffer Using Stochastic Activity Networks (SAN을 이용한 제한된 버퍼 크기를 갖는 출력큐잉 ATM 스위치 성능평가)

  • Jang, Kyung-Soo;Shin, Ho-Jin;Shin, Dong-Ryeol
    • The Transactions of the Korea Information Processing Society
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    • v.7 no.8
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    • pp.2484-2496
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    • 2000
  • High speed switches have been developing to interconnect a large number of nodes. It is important to analyze the switch performance under various conditions to satisfy the requirements. Queueing analysis, in general, has the intrinsic problem of large state space dimension and complex computation. In fact, The petri net is a graphical and mathematical model. It is suitable for various applications, in particular, manufacturing systems. It can deal with parallelism, concurrence, deadlock avoidance, and asynchronism. Currently it has been applied to the performance of computer networks and protocol verifications. This paper presents a framework for modeling and analyzing ATM switch using stochastic activity networks (SANs). In this paper, we provide the ATM switch model using SANs to extend easily and an approximate analysis method to apply A TM switch models, which significantly reduce the complexity of the model solution. Cell arrival process in output-buffered Queueing A TM switch with finite buffer is modeled as Markov Modulated Poisson Process (MMPP), which is able to accurately represent real traffic and capture the characteristics of bursty traffic. We analyze the performance of the switch in terms of cell-loss ratio (CLR), mean Queue length and mean delay time. We show that the SAN model is very useful in A TM switch model in that the gates have the capability of implementing of scheduling algorithm.

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Senescence as A Consequence of Ginsenoside Rg1 Response on K562 Human Leukemia Cell Line

  • Liu, Jun;Cai, Shi-Zhong;Zhou, Yue;Zhang, Xian-Ping;Liu, Dian-Feng;Jiang, Rong;Wang, Ya-Ping
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.12
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    • pp.6191-6196
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    • 2012
  • Aims and Background: Traditional chemotherapy strategies for human leukemia commonly use drugs based on cytotoxicity to eradicate cancer cells. One predicament is that substantial damage to normal tissues is likely to occur in the course of standard treatments. Obviously, it is urgent to explore therapies that can effectively eliminate malignant cells without affecting normal cells. Our previous studies indicated that ginsenoside $Rg_1$ ($Rg_1$), a major active pharmacological ingredient of ginseng, could delay normal hematopoietic stem cell senescence. However, whether $Rg_1$ can induce cancer cell senescence is still unclear. Methods: In the current study, human leukemia K562 cells were subjected to $Rg_1$ exposure. The optimal drug concentration and duration with K562 cells was obtained by MTT colorimetric test. Effects of $Rg_1$ on cell cycle were analyzed using flow cytometry and by SA-${\beta}$-Gal staining. Colony-forming ability was measured by colony-assay. Telomere lengths were assessed by Southern blotting and expression of senescence-associated proteins P21, P16 and RB by Western blotting. Ultrastructural morphology changes were observed by transmission electron microscopy. Results: K562 cells demonstrated a maximum proliferation inhibition rate with an $Rg_1$ concentration of $20{\mu}\;mol{\cdot}L^{-1}$ for 48h, the cells exhibiting dramatic morphological alterations including an enlarged and flat cellular morphology, larger mitochondria and increased number of lysosomes. Senescence associated-${\beta}$-galactosidase (SA-${\beta}$-Gal) activity was increased. K562 cells also had decreased ability for colony formation, and shortened telomere length as well as reduction of proliferating potential and arrestin $G_2$/M phase after $Rg_1$ interaction. The senescence associated proteins P21, P16 and RB were significantly up-regulated. Conclusion: Ginsenoside $Rg_1$ can induce a state of senescence in human leukemia K562 cells, which is associated with p21-Rb and p16-Rb pathways.

Effect of gas composition on the characteristics of a-C:F thin films for use as low dielectric constant ILD (가스 조성이 저유전상수 a-C:F 층간절연막의 특성에 미치는 영향)

  • 박정원;양성훈;이석형;손세일;오경희;박종완
    • Journal of the Korean Vacuum Society
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    • v.7 no.4
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    • pp.368-373
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    • 1998
  • As device dimensions approach submicrometer size in ULSI, the demand for interlayer dielectric materials with very low dielectric constant is increased to solve problems of RC delay caused by increase in parasitic resistance and capacitance in multilevel interconnectins. Fluorinated amorphous carbon in one of the promising materials in ULSI for the interlayer dielectric films with low dielectric constant. However, poor thermal stability and adhesion with Si substrates have inhibited its use. Recently, amorphous hydrogenated carbon (a-C:H) film as a buffer layer between the Si substrate and a-C:F has been introduced because it improves the adhesion with Si substrate. In this study, therfore, a-C:F/a-C:H films were deposited on p-type Si(100) by ECRCVD from $C_2F_6, CH_4$and $H_2$gas source and investigated the effect of forward power and composition on the thickness, chemical bonding state, dielectric constant, surface morphology and roughness of a-C:F films as an interlayer dielectric for ULSI. SEM, FT-IR, XPS, C-V meter and AFM were used for determination of each properties. The dielectric constant in the a-C:F/a-C:H films were found to decrease with increasing fluorine content. However, the dielectric constant increased after furnace annealing in $N_2$atomosphere at $400^{\circ}C$ for 1hour due to decreasing of flurorine content. However, the dielectric constant increased after furnace annealing in $N_2$atmosphere at $400^{\circ}C$ for 1hour due to decreasing of fluorine concentration.

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Development of a self-leveling system for the bucket of an agricultural front-end loader using an electro hydraulic proportional valve and a tilt sensor (전자유압 비례밸브와 경사센서를 이용한 농용 프론트 로더 버켓 능동수평유지 시스템 개발)

  • Lee, Chang Joo;Ha, Jong Woo;Choi, Deok Su;Kim, Hak Jin
    • Journal of Drive and Control
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    • v.12 no.4
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    • pp.60-70
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    • 2015
  • A front-end loader (FEL) mounted on an agricultural tractor is one of the most commonly used implements for farm work. However, when the tractor carries material using the bucket attached to the FEL on a sloping ground, the materials can spill or roll back over the operator due to the tilted body, thereby requiring the bucket surface to remain level at a constant value regardless of varying slopes. In this study, an active system for controlling the angle of the FEL bucket on a tractor based on the real-time measurement of ground slopes was developed to enable the bucket to constantly remain level. A FEL simulator operated based on an electro hydraulic proportional valve (EHPV) was constructed in the laboratory to develop a proportional-integral-derivative (PID) controller forming a virtual electronic control unit (ECU) on the computer, which could automatically adjust the bucket angles depending on varying input angles while sending SAE-J1939 associated messages via CAN BUS to the EHPV. The different parameter values for the PID controller due to the gravity effect of the bucket were determined using a manual PID tuning method while assuming that the tractor travels on either an ascending slope or a descending slope. The developed PID control-based self-leveling system showed a mean of steady-state errors of within $1^{\circ}$ and a mean of delayed times of ~ 0.8s when the step input of $+20^{\circ}$ was given, implying that the developed system and control algorithm would be effective in maintaining the bucket angle at a certain value. Future studies include the improvement of the control algorithm to reduce such a time delay as well as the application of the developed algorithm to the FEL mounted on a tractor tested at a testing ground.

Discovery of Active Nodes and Reliable Transmission of Active Packets in IP Networks (IP 망에서의 액티브 노드 발견 및 액티브 패킷의 신뢰성 전송 기법)

  • Kim, Bang-Eun;Chae, Ki-Joon;Kim, Dong-Young;Na, Jung-Chan
    • The KIPS Transactions:PartC
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    • v.11C no.3
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    • pp.361-370
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    • 2004
  • All active nudes which have no physically direct connection with each other in If network must be able to compose and manage network topology Informations. Besides one active program can be performed by the active nodes when every active packet for this program is transmitted without any loss of packets. Also the active packets should be transmitted effectively to minimize the transmission delay and securely from threatens. In this thesis, the discovery scheme of active nodes is adapted for active nodes in IP networks to compose and manage the topology information. The scheme for the efficient, reliable and secure transmission of active packets is also proposed. The sequence number is assigned to every active packet. If a receiver detects the loss of active packet checking the sequence number, the receiver requests the retransmission of the lost packet to the previous active node. kiter receiving an active packet and adapting security and reliability schemes, intermediate active nodes not only copy and send the Packet Instantly but also apply some suity mechanisms to it. And the active packet transmission engine is proposed to provide these transmission schemes The simulation of the adapted active node discovery scheme and the proposed active packet transmission engine is performed. The simulation results show that the adapted active node discovery scheme is efficient and the proposed active engine has the low latency and the high performance.

A WATM MAC Protocol for the Efficient Transmission of Voice Traffic in the Multimedia Environment (멀티미디어 환경에서 효율적인 음성 전송을 위한 WATM MAC 프로토콜)

  • 민구봉;최덕규;김종권
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.25 no.1A
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    • pp.96-103
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    • 2000
  • The voice traffic is one of the most important real-time objects in WATM(Wireless Asynchronous Transfer Mode) networks. In this paper, we propose a new MAC(Medium Access'Control) protocol for the efficienttransmission of voice traffic over WATM networks in the multimedia environment and compare the performanceto existing similar protocols. The new protocol separates the reservation slot period for voice and that for data toguarantee some level of QoS(Quality of Service) in voice traffic. This is denoted by a slot assignment functiondepending on the frame size. According to the characteristics of voice traffic which is repeatedly in silent states,the protocol allocates voice reservation request slots dynamically with respect to the number of silent(off state)voice sources and also sends the first block of talkspurt restarted after silent period with a reservation requestslot to reduce the access delay.The simulation results show that the proposed protocol has better performance than Slotted Aloha in bandwidthefficiency, and can serve a certain level of QoS by the given slot assignment function even when the number ofvoice terminals varies dynamically. This means we can observe that the new MAC protocol is much better thanthe NC-PRMA(None Collision-Packet Reservation Multiple Access) protocol.

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Context-Aware Steel-Plate Piling Process System For Improving the Ship-Building Process (선박 건조공정 개선을 위한 상황인지 컴퓨팅 기반의 강재적치처리시스템)

  • Kang, Dong-Hoon;Ha, Chang-Wan;Kim, Je-Wook;Oh, Hoon
    • Journal of the Korea Society of Computer and Information
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    • v.16 no.6
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    • pp.165-178
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    • 2011
  • A gigantic ship is constructed by assembling various types of ship blocks, each block being made by cutting and piecing the steel-plates together. The steel-plate piling process as the initial stage of ship construction sorts and manages the steel-plates according to the ship blocks that the steel-plates are used to make. The steel-plate piling process poses some problems such as process delay due to piling errors, safety vulnerability due to the handling of extra heavy-weight objects, and the uncertainty of work plan due to lack of information management in the pile spaces. We constructed a steel-plate piling process system based on the context-aware computing to resolve such problems. We built simulation system that can simulate the piling process and then established a smart space within the system by using tags, sensors and a real-time location system in order to collect context information. Workers receive an appropriate or intelligent service from the system.

A Clinical Trial of Light Therapy on Patients with Premenstrual Dysphoric Disorder (월경전 불쾌기분장애 환자의 광치료 임상 시도)

  • Joe, Sook-Haeng;Kim, Jin-Se;Kim, Seung-Hyun;Kim, Leen
    • Sleep Medicine and Psychophysiology
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    • v.6 no.1
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    • pp.46-51
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    • 1999
  • Objectives: Patients with premenstrual dysphoric disorder(or PMDD) have impairments of the social, occupational or academic function due to psychological or somatic symptoms, which have the characteristic pattern of symptom exacerbation in the week before menses begin and remission shortly after the onset of menses. In the chronobiological view, many researchers have assumed that the etiology of PMDD is the advanced circadian rhythm. It has been suggested that light has a therapeutic effect on PMDD, because evening light results in phase delay of circadian rhythm through the biochemical changes including melatonin. Methods: The authors investigated the therapeutic effect of light therapy on four patients with prospectively diagnosed PMDD by DSM-IV criteria using clinical psychiatric interview, Premenstrual Assessment Form(PAF) and Daily Rating Form(or DRF). In the evening(6:30pm-8:00pm), the 2,500 lux light administered for seven consecutive days during the symptomatic late luteal phase of menstrual cycle. Beck Depression Inventory(or BDI), Hamilton Rating Scale for Depression(or HAM-D), Spielberg State Anxiety Inventory(or SA), and DRF were evaluated before and after seven days of light therapy. Results: Premenstrual symptoms of PMDD could be effectively treated with the evening bright light therapy, especially in PMDD patients with atypical symptoms. In addition, the light therapy seemed to more effective on the psychologic symptoms than the somatic symptoms of PMDD. There was no significant side-effect of light therapy, except the transient and mild eye-strain in one case. Conclusions: In spite of the results of limited data from our clinical trial, the authors suggest that the potential use of light therapy as an alternative to the pharmacological management of patients with PMDD.

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Hospital oral and maxillofacial nursing care in Jeju province (제주 지역 병원의 구강 악안면 간호 실태)

  • Kim, Sung-Joon;Kim, Se-Il;Song, Hyo-Jeong;Kahm, Se-Hoon;Lee, Byoung-Jin
    • The Journal of the Korean dental association
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    • v.53 no.1
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    • pp.36-46
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    • 2015
  • Objectives: The objective of this work was to investigate the hospital nursing care of oral and maxillofacial health in jeju province. Methods: 438 Registered nurses(RN) who were working at each of secondary hospitals in Jeju province had responded to the questionnaire. The data were analyzed via frequency analyses and one-way ANOVA to assess the state of RN on hospital nursing care of oral and maxillofacial health. Results: The class of education on density in formal density that marked '0 hour' and '1-3 hours' were 73.5% and 19.9%, respectively. The class of refresher training on density that marked '0 hours' and '1-3 hours' were 92.9% and 6.6%, aggregately 99.5%. The nursing education on appearance after tumor of maxillofacial area that marked 'formal education' and 'none' were 45.2% and 52.1%, respectively. The score of question 'function, effect and side effect of hexamedin gaggle' was $2.68{\pm}0.95$ by Likert 5-point scale. Likewise, the scores were $2.82{\pm}0.88$ on question 'management of removal denture', $2.83{\pm}0.95$ on question 'preventive dental treatment before anticancer therapy', $2.88{\pm}0.86$ on question 'function of saliva', $2.96{\pm}0.99$ on question 'oral management of tube feeding patient', $3.13{\pm}1.00$ on question 'bacterial endocarditis from oral microflora', $3.36{\pm}0.89$ on question 'dysphagia' and $3.62{\pm}1.03$ on question 'aspiration pneumonia'. RN replied that 'lack of knowledge' and 'delay of cooperation' formed 53.7% and 33.3% respectively, on question 'problem in dental consultation other diseased patient'. Conclusions: From this study, it is necessary for RN and student of nursing science to be educated on the oral and maxillofacial nursing. Authors suggest further co-study and nation-wide research.

Wall Shear Stress Distribution in the Abdominal Aortic Bifurcation : Influence of wall Motion, Impedance Phase Angle, and non-Newtonian fluid (복부대동맥 분기관에서의 벽면전단응력 분포 벽면운동과 임피던스 페이즈 앵글과 비뉴턴유체의 영향)

  • Choi J.H.;Kim C.J.;Lee C.S.
    • Journal of Biomedical Engineering Research
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    • v.21 no.3 s.61
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    • pp.261-271
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    • 2000
  • The present study investigated flow dynamics of a two-dimensional abdominal aortic bifurcation model under sinusoidal flow conditions considering wall motion. impedance phase angle(time delay between pressure and flow waveforms), and non-Newtonian fluid using computational fluid dynamics. The wall shear stress showed large variations in the bifurcated region and the wall motion reduced amplitude of wall shear stress significantly. As the impedance phase angle was changed to more negative values, the mean wall shear stress (time-averaged) decreased while the amplitude (oscillatory) of wall shear stress increased. At the curvature site on the outer wall where the mean wall shear stress approached zero. influence of the phase angle was relatively large. The mean wall shear stress decreased by $50\%$ in the $-90^{\circ}$ phase angle (flow wave advanced pressure wave by a quarter period) compared to the $0^{\circ}$ phase angle while the amplitude of wall shear stress increased by $15\%$. Therefore, hypertensive patients who tend to have large negative phase angles become more vulnerable to atherosclerosis according to the low and oscillatory shear stress theory because of the reduced mean and the increased oscillatory wall shear stresses. Non-Newtonian characteristics of fluid substantially increased the mean wall shear stress resulting in a less vulnerable state to atherosclerosis.

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