• Advances in Traditional Medicine
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• v.8 no.1
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• pp.24-31
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• 2008

In the present investigation, we studied the effect of alcoholic extract of Moringa oleifera (M. oleifera) seed kernels on various experimental models of bronchial asthma. Significant (P < 0. 05) increase in preconvulsion time was observed due to pretreatment with M. oleifera when the guinea pigs were exposed to either acetylcholine (Ach) or histamine aerosol. This bronchodilating effect of M. oleifera was comparable to ketotifen fumarate. Spasmolytic effect of M. oleifera was also observed by dose dependent inhibition of ideal contractions induced by Ach, 5HT, histamine and $BaCl_2$. Alcoholic extract of M. oleifera produced significant dose dependent protection by egg albumin and compound 48/80 induced mast cell degranulation. Pretreatment with alcoholic extract of M. oleifera also decreased carrageenan induced rat paw edema, which was comparable to that of standard diclofenac sodium. Minimum inhibitory concentration for alcoholic extract of M. oleifera was low as compared to cold-water extract and hot water extract when antimicrobial activity was tested against various respiratory pathogens like Escherichia coli (E. coli), Staphylococus aureus (S. aureus) and pseudomonas aeruginosa (P. aeruginosa). Our data suggest that antiasthmatic activity of M. oleifera seed kernels may be due to its bronchodilator, anti-inflammatory, mast cell stabilization and antimicrobial activity.

• Journal of the Korean Crystal Growth and Crystal Technology
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• v.21 no.5
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• pp.210-213
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• 2011

Glass-ceramics composed of $5Na_2O-36CaO-10TiO_2-xP_2O_5$ could be obtained with $P_2O_5$ content as following procedure: 1) leaching out $Ca_3(PO_4)_2$ crystals between $Ca_3(PO_4)_2$ and $NaTi_2(PO_4)_3$ selectively in 1 N HCl solution for 2 days, and 2) exchanging $Na^+$ ion to $Ag^+$ ion in Ag($NO_3$) solution for 1 day. Scanning electron microscope (SEM) and X-rat diffractometer (XRD) were measured to verify the proper synthesis of glass-ceramics. And anti-bacteria test was accomplished using Staphylococus aureus bacteria. In the results of anti-bacteria test, the bacteria were died perfectly after 3 hours.

• Journal of the Korean Society of Food Science and Nutrition
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• v.16 no.4
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• pp.364-370
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• 1987

A lysozyme is isolated and purified partially form the egg white of Korean native Ogol fowl(Natural monument No. 265) by the method of direct crystallization. The bacteriolytic activities of 1% lysozyme against Staphylococus aureus 57, Bacillus subtilis ATCC 6633, and Escherichia coli NIHJ-JC2 was investigated with or without some other antibacterial materials in the nutrient broth culture. According to the results, 1% lysozyme showed the appreciable bacterolytic activities of about 12-16% to the almost of bacteria cultured. The synergistic effect with the lysozyme and some antibacterial materials on the growth inhibition of the bacteria cultured exhibited higher in order of the 0.001% magnolol -22%, the 0.001% honokiol -14% against S. aureus and of the 0.0005% erythromcin -29%, the honokiol -22%, the magnolol -l7%, the 0.005% phospholipase -6% against E. coli. And that synergistic effect against B. subtilis showed a fairly high level of about 52% with the erythromycin but not any effect with others.

• Journal of Pharmaceutical Investigation
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• v.39 no.6
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• pp.431-435
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• 2009

The comparative superior in vitro activity of DW-224a was supported by the downward MIC distribution due to the weakened influence of alterations within target enzymes in ciprofloxacin-resistant Staphylococcus aureus. The MI$C_{50}$ for DW-224a was 4 $\mu$g/mL, similar to that of gemifloxacin, 8-fold less than that of sparfloxacin and 16-over-fold less than that of ciprofloxacin. We constructed combinations of amino acid changes, located at codon 80, 83 or 84 within GrlA and 84, 85 or 88 within GyrA, which were associated with MIC increase. The amino acid changes were less influential to the MIC of DW-224a compared to those of other fluoroquinolones, and it was verified from the requirement of a total of two GrlA- and two GyrA-alterations to reach the MIC of DW-224a over 32 $\mu$g/mL.

• Korean Journal of Food Science and Technology
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• v.29 no.4
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• pp.808-816
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• 1997

Fifty six kinds of medicinal herbs were extracted by 75% ethanol and antimicrobial activity of the extracts were tested against food-born bacteria, Listeria monocytogenes ATCC 15313, 19111, 19112, 19113, 19114, Bacillus cereus YUFE 2004, Staphylococcus aureus KFCC 11764, Pseudomons fluorescens KCTC 1645, 2344 and Leuconostoc mesenteroides KFCC 12031. Ethanol extracts of Terminalia chebula Rets, Rosa laevaigate Michx, Caesalpinia sappan L and Myristica fragrans Houtt showed inhibitory effects on the growth of most of the strains tested. In particular, the extract of Terminalia chebula Rets showed obvious growth inhibition in proportion to the concentration and Caesalpinia sappan L stopped the growth in the concentration of 100 ppm on several strains. Also, ethylacetate fractionates of Terminalia chebula Rets, Rosa laevaigate Michx, and Caesalpinia sappan L and chloroform fractionate of Myristica fragrans Houtt showed more effective inhibitory action on the growth of most of the strains tested.

• The Korean Journal of Mycology
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• v.32 no.2
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• pp.145-147
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• 2004

The ethyl acetate extracts from the liquid cultures of Coriolus versicolor, Phellinus linteus, and Hericium erinaceus showed significant antibacterial activities against Escherichia coli K88, E. coli K99, E. coli 987P, and Salmonella typhimurium 14058 causing bacterial diarrhea in Korean house pigs and chicken. Of these extracts, Coriolus versicolor extract showed the highest antibacterial activity. In addition, these extracts also showed significant growth inhibition against Staphylococcus aureus CARM3230 and E. coli CARM1381 which are known as kanamycin and ampicillin-resistant strains. These results showed that the mushroom extracts could be developed as a livestock feed additives that can replace commercial antibiotics, and also could be good resources for the development of a new antibacterial agent.

• Journal of the Korean Ceramic Society
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• v.38 no.11
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• pp.1055-1059
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• 2001

Porous glass ceramics composed of Li$_2$O.-Ti $O_2$-P$_2$ $O_{5}$ -CaO were prepared by melting and 2 step heat treatment for nucleation at 61$0^{\circ}C$ and crystallization at 78$0^{\circ}C$. subsequently $\beta$-Ca$_3$(P $O_4$)$_2$crystal phase was selectively leached out in 1N-HC1 solution for 3 days, leaving Li $Ti_2$(P $O_4$)$_3$crystal phases. prepared porous glass ceramics were immersed in 1M AgN $O_3$solution for ion exchange. Staphylococcus aureus and salmonella typhi were used in this study. It was found taht the resultant porous glas ceramics show excellent bacteriostatic properties.

• Biomolecules & Therapeutics
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• v.16 no.4
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• pp.356-363
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• 2008

A bacterial strain with good antibacterial activities against Staphylococus aureus and Escherichia coli was isolated from a marine sponge Stelleta sp., and it was identified as a Psychrobacter sp. by comparative 16S rDNA sequence analysis. In our search for bioactive secondary metabolites from this psychrophillic and halotolerent bacterium, sixteen cyclic dipeptides (1-16) were isolated and their structures were identified on the basis of NMR analysis. In the test of the compounds for the protective effect against Vibrio vulnificusinduced cytotoxicity in human intestinal epithelial cells, cyclo-(L-Pro-L-Phe) (5) exhibited significant protective effect. Compounds 2, 6, and 11, which contain D-amino acid, were first isolated from bacteria.

• International Journal of Industrial Entomology and Biomaterials
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• v.39 no.1
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• pp.39-44
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• 2019

The effect of heat treatment on the sterilization and fatty acid compositions of silkworm powder was carried out under the guidance of Ministry of Food and Drug Safety. Food borne pathogens or microorganisms including E. coli, Salmonella spp., Listeria monocytogenes, Staphylococus aureus, Clostridium perfringens and aflatoxin, were not detected. The fatty acid composition was hardly changed after the silkworm powder was treated to a high temperature of $121^{\circ}C$. The low temperature sterilization of silkworm powder at $63^{\circ}C$ decreased the concentration of E. coli while high temperature sterilization at $121^{\circ}C$ has found no traces of microorganism.

• Korean Journal of Food Science and Technology
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• v.37 no.2
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• pp.287-293
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• 2005

Microbial contamination levels in commercial strawberry juices were examined for sanitary indication bacteria, such as aerobic plate count (APC), coliforms, and Escherchia coli, and pathogenic bacteria such as E. coli O157:H7, Salmonella spp., Staphylococcus aureus, and Listeria monocytogenes. APC and coliform count ranged 0-5.2 and $0-2.8\;log_{10}\;CFU/(mL,\;g,\;100cm^{2},\;hand)$, respectively, and 80% strawberry juices were contaminated with E. coli and S. aureus, detected at 19%, was found in employee's hands, strawberries, and strawberry juices, whereas E. coli O157:H7, Salmonella spp, and L. monocytogenes were not detected. These results will provide microbiological information for introduction of Hazard Analysis Critical Control Point (HACCP) system in juice shops.