• 대한암한의학회지
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• 제16권1호
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• pp.41-53
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• 2011

Background and Objectives: Iodine is an essential constituent of the thyroid hormones associated with the growth and development of humans and animals as an inorganic nutrition. This element may be accumulated in human blood, tissues and body through the intake of foodstuffs, a beverage, a nutritional supplement and a medicine, among others. The aim of the research is to find out a better medicinal stuff for the thyroid cancer patient who required a low level of iodine diet. Methods: Neutron activation analysis (NAA) used for the iodine analysis is one of nuclear analytical techniques using radiation and radioisotopes and very useful as sensitive analytical technique for performing both qualitative and quantitative multi-elemental non-destructive analysis of major, minor and trace components in variety of environmental and biological materials. In this study, iodine contents in ten kinds of oriental herb medicinal products, which is frequently used to cancer patients are determined by using instrumental neutron activation analysis (INAA) at the HANARO research reactor. The samples prescribed are manufactured as powdered form for taking medicine easily. The analytical quality control is performed to assure an uncertainty of the measurement and to compensate the measured data using a biological certified reference material, NIST SRM 1572, Citrus Leaves. The measured value is $1.89{\pm}0.35mg/kg$, and the relative error is 2.88%, and relative standard deviation is 19 % due to high counting error by small counts of gamma ray spectrum. The standard deviations for other elements such as Cl, K, Mn and Na were in the range of 2 to 8%. Result: The level of iodine contents of Biki-huan, Chungryong-huan and Chungcho-huan, samples detected is less than 6 mg/kg except Hangam Plus sample (more than 210 mg/kg) and six samples were not detected. Iodine in the samples of Shoxiho-tang, Shopunghualhyl-tang, Shocungryong-tang, Banhasaxim-tang, Insampaedox-san and Myunyuk Plus were not measured, but possible level of content can be estimated from the detection limits. In addition, the concentrations of some major elements like Cl, K, Mn, Na, in the samples were determined with the detection limits. Conclusions: Most of samples showed low iodine contents of less than 6 mg/kg but it turned out that most of testing samples can be used to classify the level of iodine diet samples considering the recommended low level of iodine diet 50 ${\mu}g$/day, and a better medicinal stuff for the thyroid cancer patient can be found.

• 한국수자원학회논문집
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• 제37권3호
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• pp.249-255
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• 2004

농업용수 회귀율을 조사하기 위하여 2003년 관개기 동안 많은 실측을 수행하였다. 본 연구지역은 경상남도 창녕군에 위치한 대암양수장 유역일원이다. 관개용수를 공급하기위하여 건설된 대암 양수장 유역 내 논에 대하여 물수지분석을 실시하였다. 본 연구지역에서의 일 강우량 자료를 수집하였으며, 또한 관개율, 배수율, 침투 및 증발산을 실측하였다. 관개량과 배수량은 기록형수위계(GTDL-L10)를 설치하여 관계기 동안 지속적으로 관측하였다 침투 및 증발산은 직경 3mm PVC 감수심계 및 직경 200mm PVC 침투계를 이용하여 측정하였다. 총관개량 및 총 지표배수량은 654.7mm와281.2mm로 나타났으며, 총 침투량과 총증발산량은 각각 36.0mm 및 160.0mm였고, 일평균 증발산량은 4.3mm/d 였다. 신속회귀율과 지연회귀율은 각각 43.0% 및 5.5%로 전체회귀율은 48.5 %로 나타났다. 따라서, 본 시험지구에서 공급된 관개용수량이 설계기준보다 훨씬 많은 양의 관개용수를 공급하고 있음을 알 수 있었다. 이는 적정한 용수관리원칙 보다는 지역주민들의 요구에 의한 과다공급으로 인한 부적적한 용수관리에 기인하는 것으로, 추후에 농업용수설계기준을 현실에 맞게 변경해야함을 의미한다.

• 패션비즈니스
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• 제5권2호
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• pp.129-147
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• 2001

The purpose of this study is to survey and analyze domestic fashion education institution's program on apparel prototype and thereupon, address the problems and find their solutions, and thereby, provide for some basic data useful to improve the basic patterns of apparel and ultimately, help reinforce the professional and practical apparel design education. The results of this study can be summarized as follows; 1. 85.1% of the subjects finished graduate or higher courses. Almost all of the college and junior college teachers finished graduate or higher courses, while only 31.6% of those teaching at technical institutes finished graduate or higher courses. Such a finding suggests that colleges tend to employ their faculty members based on their academic background but that technical institutes value the practical ability of their faculty more. 2. As a result of surveying the types of basic patterns used by teachers, it was found that 72.3% of them were using two or more patterns. The basic pattern preferred most by our teachers was Japanese culture institute's type (71.3%), followed by the US FIT type (24.5%), Lim Won-Ja's type (22.3%), French ESMOD type (17.0%). 96.3% of our apparel design students were making their basic patterns as instructed by their teachers. 3. 67.0% of our students were using their conceived sizes for production of their basic patterns, 14.9% were referring to the ready-made sizes, 8.5% were relying on their teachers' individual experiences, and 9.6% were using their own cord sizes. In order to survey the difference between teachers' sizes (ready-made sizes or individual experienced ones) and business sizes used, the basic body measurements used for ready-made apparels were surveyed to be compared with the national standard body sizes set in 1997 for women aged between 18 and 24. As a result, it was found that the ready-made sizes used for apparel production prototypes than teachers' ones were nearer the national standard sizes. Such a finding suggests that it may well be necessary for teachers to be more connected with the apparel businesses and thereby, teach their students in a more realistic way with correct information. 4. 83.0% of the subject teachers were tacking their basic patterns to be well fitting, and 76.9% of these teachers were tacking the patterns in reference with students' individual body sizes. In all, 97.4% of the subject teachers were guiding the tacking process, which suggests that the flat patternmaking is taught primarily for customized apparels. As a result of comparing the fitness of basic patterns with those of each body part, it was found that teachers were most dissatisfied with the fitness of shoulders and arm hole depth. Therefore, it will be necessary to reclassify the body types or find other drawing techniques to improve the fitness of such body parts. Nevertheless, teachers were willing much (4.18) to develop their own educational basic patterns for themselves. Lastly, it is hoped that this study will be followed up by future studies on educational prototypes covering diverse body shapes and those on practical implementations of those prototypes for students.

• 한국전산구조공학회논문집
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• 제13권1호
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• pp.63-74
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• 2000

본 연구는 해외각국의 RC건물의 내진화기술 가운데, 일본의 기존 RC건물에 대한 내진성능의 평가수법인 내진진단규준의 현황을 소개함과 동시에 그 적용사례 및 지진대책에의 활용가능성을 분석·검토하여, 향후 한국실정에 맞는 RC건물의 내진화기술의 개발에 기초적인 자료로서 활용하고자 하는 것이 주목적이다. 이를 위해 본 연구에서는 일본의 동경도에서 최근 실시되어진 지진경험이 없는 RC건물의 내진성능을 내진진단규준에 의한 진단결과인 구조내 진지표(Is)치를 중심으로 통계학적으로 분석하여, 이미 조사되어진 타 지역의 내진성능과 비교·검토하였고, 또한 확률론에 입각하여 대상지역의 Is치의 분포특성과 이미 지진 피해를 받은 지역 건물의 Is치 분포특성을 비교·검토하여 지진피해율을 추정하였다. 본 연구의 결과는 지진에 대한 보강건물의 효율적인 선정 등, 지진대책에 기본적인 자료로서 활용이 가능하며, 또한 일본의 내진성능 평가방법, 통계학적인 분석방법, 확률론에 입각한 지진피해율 평가방법 등의 방법론은 향후 한국의 RC건물에 대한 내진화기술의 개발에 활용이 가능하다고 사료된다.

• 한국수자원학회논문집
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• 제46권6호
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• pp.613-627
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• 2013

본 연구에서는 지속기간별(1-, 3-, 6-, 12-, 24개월)로 가장 가뭄이 심한 해의 5월 건조현상을 지역별로 분석하기 위해 1973년부터 2006년까지 우리나라 53개 기후관측지점에서 관측된 월별 기후자료를 이용하여 FAO Penman-Monteith 기준잠재증발산량(RET)을 산정하였다. 그리고 강수량(P)에 대한 RET의 비(P/RET)를 이용하여 건조지수(aridity index)와 P/RET의 변동지수(variation index, VI)를 산정하고, 표준강수지수(standard precipitation index, SPI)와 비교하였다. 우리나라 지역별 건조현상을 파악하기 위해 53개 기후관측지점을 20개 연구지역으로 구분하여 분석하였다. 또한 지역별 건조지수의 추세분석을 위해 Mann-Kendall 추세분석, Spearman rank test 그리고 Sen's slope을 적용하였다. 분석 결과에 의하면 각 지속기간별로 P/RET의 변동지수(VI)와 표준강수지수사이에 양호한 상관관계를 보였다. 또한 우리나라 전역에 걸쳐서 지속기간이 단기화 될수록 5월 기후가 더욱 건조한 것으로 나타났다. 3개월이나 6개월 지속기간의 경우 대부분 지역에서 유의하거나 혹은 유의하지 않은 수준에서 건조지수의 감소추세를 보였다. 반면에 12개월 및 24개월 지속기간의 경우 유의한 건조지수의 감소추세를 보이는 지역은 없는 것으로 나타났다.

• 한국화재조사학회지
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• 제6권1호
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• pp.49-66
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• 2005

이 연구는 아트리움의 방화안전성 고찰 및 적정한 방화 장치의 기준제시를 초점으로 하고 있다. 주요 내용으로는 아트리움 공간의 일반적 고찰, 아트리움 건물의 실례와 방재상의 문제점을 알아보았고, 현재 우리나라 아트리움 공간에 설치되어 있는 방화설비 등을 조사하여 외국의 여러 기준과 비교함으로써 드러난 문제점 및 취약요인을 바탕으로 아트리움 설계 시 특히 유의하여야 할 사항에 대하여 탐구하였다. 여기서 주장한 아트리움 공간의 효과적인 소화설비기준은 다음과 같다. 1 제연 설비는 비상동력이 부설된 기계제연에 의한 강제배연이 알맞다. 2 아트리움 공간과 연결된 다른 부분에서 공기의 유입이 되지 않도록 연결된 부분(1층 제외)을 화재 시 지동으로 구획되는 가동벽 셔터 방화문을 설치한다. 3. 분리형 적외선 감지기를 아트리움 바닥으로부터 7~8m 높이에 설치하여 조기에 화재를 감지하도록 한다. 4. 천장이 20m이하인 아트리움의 경우 아트리움 천장에 개방형 스프링클러헤드를 설치하고 일제개방밸브를 작동시켜 해당구역에 소화수를 집중 방출하게 하며, 천장이 20m이상인 아트리움의 경우 측벽형 헤드를 저층부의 벽체에 설치하여 수평분출로 소화한다. 5. 피난 계단으로의 이동은 아트리움 공간을 지나지 않고 할 수 있도록 설계되어야한다. 6. 일부부재의 내력저하가 생겨도 전체의 붕괴에는 이르지 않게, 아트리움의 철골의 트러스재는 내화재로 보호한다.

• Korean Journal of Radiology
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• 제22권6호
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• pp.867-879
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• 2021

Objective: To compare the screening performance of diffusion-weighted (DW) MRI and combined mammography and ultrasound (US) in detecting clinically occult contralateral breast cancer in women with newly diagnosed breast cancer. Materials and Methods: Between January 2017 and July 2018, 1148 women (mean age ± standard deviation, 53.2 ± 10.8 years) with unilateral breast cancer and no clinical abnormalities in the contralateral breast underwent 3T MRI, digital mammography, and radiologist-performed whole-breast US. In this retrospective study, three radiologists independently and blindly reviewed all DW MR images (b = 1000 s/mm² and apparent diffusion coefficient map) of the contralateral breast and assigned a Breast Imaging Reporting and Data System category. For combined mammography and US evaluation, prospectively assessed results were used. Using histopathology or 1-year follow-up as the reference standard, cancer detection rate and the patient percentage with cancers detected among all women recommended for tissue diagnosis (positive predictive value; PPV2) were compared. Results: Of the 30 cases of clinically occult contralateral cancers (13 invasive and 17 ductal carcinoma in situ [DCIS]), DW MRI detected 23 (76.7%) cases (11 invasive and 12 DCIS), whereas combined mammography and US detected 12 (40.0%, five invasive and seven DCIS) cases. All cancers detected by combined mammography and US, except two DCIS cases, were detected by DW MRI. The cancer detection rate of DW MRI (2.0%; 95% confidence interval [CI]: 1.3%, 3.0%) was higher than that of combined mammography and US (1.0%; 95% CI: 0.5%, 1.8%; p = 0.009). DW MRI showed higher PPV2 (42.1%; 95% CI: 26.3%, 59.2%) than combined mammography and US (18.5%; 95% CI: 9.9%, 30.0%; p = 0.001). Conclusion: In women with newly diagnosed breast cancer, DW MRI detected significantly more contralateral breast cancers with fewer biopsy recommendations than combined mammography and US.

• Korean Journal of Radiology
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• 제25권6호
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• pp.575-588
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• 2024

Objective: Differentiating intracranial aneurysms from normal variants using CT angiography (CTA) or MR angiography (MRA) poses significant challenges. This study aimed to evaluate the efficacy of proton-density MRA (PD-MRA) compared to high-resolution time-of-flight MRA (HR-MRA) in diagnosing aneurysms among patients with indeterminate findings on conventional CTA or MRA. Materials and Methods: In this retrospective analysis, we included patients who underwent both PD-MRA and HR-MRA from August 2020 to July 2022 to assess lesions deemed indeterminate on prior conventional CTA or MRA examinations. Three experienced neuroradiologists independently reviewed the lesions using HR-MRA and PD-MRA with reconstructed voxel sizes of 0.25³ mm³ or 0.2³ mm³, respectively. A neurointerventionist established the gold standard with digital subtraction angiography. We compared the performance of HR-MRA, PD-MRA (0.25³-mm³ voxel), and PD-MRA (0.2³-mm³ voxel) in diagnosing aneurysms, both per lesion and per patient. The Fleiss kappa statistic was used to calculate inter-reader agreement. Results: The study involved 109 patients (average age 57.4 ± 11.0 years; male:female ratio, 11:98) with 141 indeterminate lesions. Of these, 78 lesions (55.3%) in 69 patients were confirmed as aneurysms by the reference standard. PD-MRA (0.25³-mm³ voxel) exhibited significantly higher per-lesion diagnostic performance compared to HR-MRA across all three readers: sensitivity ranged from 87.2%-91.0% versus 66.7%-70.5%; specificity from 93.7%-96.8% versus 58.7%-68.3%; and accuracy from 90.8%-92.9% versus 63.8%-69.5% (P ≤ 0.003). Furthermore, PD-MRA (0.25³-mm³ voxel) demonstrated significantly superior per-patient specificity and accuracy compared to HR-MRA across all evaluators (P ≤ 0.013). The diagnostic accuracy of PD-MRA (0.2³-mm³ voxel) surpassed that of HR-MRA and was comparable to PD-MRA (0.25³-mm³ voxel). The kappa values for inter-reader agreements were significantly higher in PD-MRA (0.820-0.938) than in HR-MRA (0.447-0.510). Conclusion: PD-MRA outperformed HR-MRA in diagnostic accuracy and demonstrated almost perfect inter-reader consistency in identifying intracranial aneurysms among patients with lesions initially indeterminate on CTA or MRA.

• Korean Journal of Radiology
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• 제23권3호
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• pp.322-332
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• 2022

Objective: CT plays a central role in determining the resectability of pancreatic cancer, which directs the use of neoadjuvant therapy. This study aimed to assess the diagnostic accuracy of CT in predicting circumferential resection margin (CRM) involvement in patients with resectable or borderline resectable pancreatic head cancer. Materials and Methods: Seventy-seven patients who were scheduled for upfront surgery for resectable or borderline resectable pancreatic head cancer were prospectively enrolled, and 75 patients (38 male and 37 female; mean age ± standard deviation, 68 ± 11 years) were finally analyzed. The CRM status was evaluated separately for the superior mesenteric artery (SMA) and posterior and superior mesenteric vein/portal vein (SMV/PV) margins. Three independent radiologists reviewed the preoperative CT images and evaluated the resection margin status. The reference standard for CRM status was pathologic examination of pancreaticoduodenectomy specimens in an axial plane perpendicular to the axis of the second portion of the duodenum. The diagnostic accuracy of CT was assessed for overall CRM involvement, defined as involvement of the SMA or posterior margins (per-patient analysis), and involvement of each of the three resection margins (per-margin analysis). The data were pooled using a crossed random effects model. Results: Forty patients had pathologically confirmed overall CRM involvement in pancreatic cancer, while CRM involvement was not seen in 35 patients. For overall CRM involvement, the pooled sensitivity and specificity were 15% (95% confidence interval: 7%-49%) and 99% (96%-100%), respectively. For each of the resection margins, the pooled sensitivity and specificity were 14% (9%-54%) and 99% (38%-100%) for the SMA margin, 12% (8%-46%) and 99% (97%-100%) for the posterior margin; and 37% (29%-53%) and 96% (31%-100%) for the SMV/PV margin, respectively. Conclusion: CT showed very high specificity but low sensitivity in predicting pathological CRM involvement in pancreatic cancer.

• 한국근적외분광분석학회:학술대회논문집
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• 한국근적외분광분석학회 2001년도 NIR-2001
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• pp.1141-1141
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• 2001

The aim of the study was to evaluate the performance of 3 calibration methods, modified partial least squares (MPLS), local PLS (LOCAL) and artificial neural network (ANN) on the prediction of chemical composition of forages, using a large NIR database. The study used forage samples (n=25,977) from Australia, Europe (Belgium, Germany, Italy and Sweden) and North America (Canada and U.S.A) with information relative to moisture, crude protein and neutral detergent fibre content. The spectra of the samples were collected with 10 different Foss NIR Systems instruments, which were either standardized or not standardized to one master instrument. The spectra were trimmed to a wavelength range between 1100 and 2498 nm. Two data sets, one standardized (IVAL) and the other not standardized (SVAL) were used as independent validation sets, but 10% of both sets were omitted and kept for later expansion of the calibration database. The remaining samples were combined into one database (n=21,696), which was split into 75% calibration (CALBASE) and 25% validation (VALBASE). The chemical components in the 3 validation data sets were predicted with each model derived from CALBASE using the calibration database before and after it was expanded with 10% of the samples from IVAL and SVAL data sets. Calibration performance was evaluated using standard error of prediction corrected for bias (SEP(C)), bias, slope and R2. None of the models appeared to be consistently better across all validation sets. VALBASE was predicted well by all models, with smaller SEP(C) and bias values than for IVAL and SVAL. This was not surprising as VALBASE was selected from the calibration database and it had a sample population similar to CALBASE, whereas IVAL and SVAL were completely independent validation sets. In most cases, Local and ANN models, but not modified PLS, showed considerable improvement in the prediction of IVAL and SVAL after the calibration database had been expanded with the 10% samples of IVAL and SVAL reserved for calibration expansion. The effects of sample processing, instrument standardization and differences in reference procedure were partially confounded in the validation sets, so it was not possible to determine which factors were most important. Further work on the development of large databases must address the problems of standardization of instruments, harmonization and standardization of laboratory procedures and even more importantly, the definition of the database population.