• Title/Summary/Keyword: Standard Strategy

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Selective Extraction and Quantification of Glutathione using Maleimide-Presenting Gold Nanoparticles

  • Oh, Hongseok;Lee, Jeongwook;Yeo, Woon-Seok
    • Bulletin of the Korean Chemical Society
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    • v.35 no.10
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    • pp.3047-3051
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    • 2014
  • In this paper, we describe a new method for the selective extraction and quantification of glutathione (GSH) using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) and maleimide-presenting gold nanoparticles (Mal-AuNPs). Our strategy utilizes the Michael addition to selectively extract GSH, from chosen samples, onto the maleimide of Mal-AuNPs. After the extraction step, the GSH bound to the AuNPs was analyzed by MALDI-TOF MS in the presence of an internal standard which was prepared by reacting Mal-AuNPs with isotope-labeled GSH ($GSH^*$). The $GSH^*$ has the same structure as GSH but a higher molecular weight, and therefore, enables absolute quantification of GSH by comparing the mass signal intensities of the GSH- and $GSH^*$-conjugated alkanethiols. Our strategy was verified by analyzing GSH-spiked fetal bovine serum and NIH 3T3 cells.

The Clothing Purchasing Behaviors between Korean and American College Women

  • Im, Sung-Kyung;Han, Myung-Sook
    • The International Journal of Costume Culture
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    • v.9 no.2
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    • pp.149-159
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    • 2006
  • The purpose of the study is to compare the clothing purchasing behaviors between Korean and American college women and to gather a basic data to establish a clothing marketing strategy and effective world marketing strategy in the fashion marketing. 1,150 questionaries were distributed to 3 universities in Korea and 3 universities America from March, 15 to 30 in 2006 and a total of 800 questionnaires, 466 from Korea and 334 from American, were utilized in the final analysis. The SPSS 12.0 was used to analyze the technical statistics like average and frequency, t-test, X$^2$, factor analysis and multi-variate analysis of variance.

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A Study on Developing the Outcome Management System of Construction and Transportation R&D Project (건설교통R&D 사업의 성과관리체계에 관한 연구)

  • Jung, Si-Kyo;Moon, Dae-Seop;Maeng, Hee-Young
    • Journal of the Korean Society for Railway
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    • v.12 no.6
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    • pp.967-973
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    • 2009
  • Construction and Transportation R&D budget is increased every year. Therefore, outcome is important issue. Also, we must try for practical use of outcome. And we need strategy for practical use of outcome. This is research for the application of research and development outcome. Specially, this research studies about way for construction standard. And this proposes a institutional improvement. First, it catch a problem point with present condition analysis. Second, It executes a survey and analysis. Finally it presents some policy suggestion. This research solves two problems. This applies to the field of research and development outcome. Another this amend construction standard.

A Study on Characteristics of Performance and Emission by CRDI Engine's Injection Strategy (커먼레일 디젤기관에서 분사전략에 따른 성능 및 배출가스에 관한 연구)

  • Eom, Dong-Seop;Ko, Dong-Kyun;Ra, Wan-Yong;Lee, Seang-Wock
    • Journal of ILASS-Korea
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    • v.16 no.3
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    • pp.134-139
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    • 2011
  • Recent research has focused on engine combustion technology as well as application of after-treatment in order to comply with emission regulation. However, it is much more efficient way to control emissions from engine itself and furthermore research on engine control will provide the direction of after-treatment technology in future. Furthermore, emission standard regulation for passenger diesel vehicles has been stringent compared to others and nano-particles will be included in EURO6 regulation in Europe and similar emission standard will be introduced in Korea. A 3.0 liter high speed diesel engine equipped with by CRDI system of 160MPa injection pressure, and an intake/exhaust system of V type 6 cylinder turbo-intercooler was applied. The injection duration and injection quantity, pilot injection types which are related to CRDI and air/fuel ratio control applied by EVGT were changed simultaneously. Standard experiment procedure constituted dilution apparatus and CPC system to collect nano-particles and these test results were compared with regulated materials of CO, HC, NOx and investigated their relations and characteristics of nano-particles.

New Helicobacter pylori Eradication Therapies (새로운 헬리코박터 제균 요법)

  • Park, Jae Yong;Kim, Jae Gyu
    • The Korean Journal of Gastroenterology
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    • v.72 no.5
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    • pp.237-244
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    • 2018
  • While the prevalence of Helicobacter pylori (H. pylori) infection is decreasing in Korea, the incidence of gastric cancer remains high, emphasizing the importance of H. pylori eradication. A new treatment strategy is needed as the eradication rate with standard triple therapy, which is currently the standard first-line regimen for H. pylori infection, has decreased below the optimum level. The major cause of eradication failure is increased antibiotic resistance. Sequential, concurrent, and hybrid therapies that include clarithromycin produce higher eradication rates than conventional standard triple therapy. However, the effectiveness of these treatments is limited in regions where the resistance rate to various antibiotics is high. Bismuth quadruple therapy is another alternative therapy, but again the eradication rate is not sufficiently high. Tailored therapy based on individual characteristics, including antibiotic susceptibility, may be ideal, but there are several limitations for clinical application and further research is needed. New potassium-competitive acid blocker-based therapies could emerge as effective alternatives in the near future. A consensus is needed to establish a strategy for applying new eradication therapies in Korea.

New Active Damping Strategy for LCL-Filter-Based Grid-Connected Inverters with Harmonics Compensation

  • Hu, Guozhen;Chen, Changsong;Shanxu, Duan
    • Journal of Power Electronics
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    • v.13 no.2
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    • pp.287-295
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    • 2013
  • The use of LCL filters in pulse width modulation voltage source converters is a standard solution for providing proper attenuation of high-order grid-current harmonics. However, these filters can cause the undesired effect of resonance. This paper proposes an active damping strategy with harmonics compensation. It can alleviate the harmonics around the resonance frequency caused by the LCL filters. The proposed strategy is attractive since it is simple, does not depend on grid parameters and does not increase the number of sensors. Simulation and experimental results verify the effectiveness of the proposed active damping strategy.

A Simulation Study on Improvements of Speech Processing Strategy of Cochlear Implants Using Adaptation Effect of Inner Hair Cell and Auditory Nerve Synapse (청각신경 시냅스의 적응 효과를 이용한 인공와우 어음처리 알고리즘의 개선에 대한 시뮬레이션 연구)

  • Kim, Jin-Ho;Kim, Kyung-Hwan
    • Journal of Biomedical Engineering Research
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    • v.28 no.2
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    • pp.205-211
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    • 2007
  • A novel envelope extraction algorithm for speech processor of cochlear implants, called adaptation algorithm, was developed which is based on a adaptation effect of the inner hair cell(IHC)/auditory nerve(AN) synapse. We achieved acoustic simulation and hearing experiments with 12 normal hearing persons to compare this adaptation algorithm with existent standard envelope extraction method. The results shows that speech processing strategy using adaptation algorithm showed significant improvements in speech recognition rate under most channel/noise condition, compared to conventional strategy We verified that the proposed adaptation algorithm may yield better speech perception under considerable amount of noise, compared to the conventional speech processing strategy.

Replacement model under warranty with age-dependent minimal repair

  • Park, Minjae
    • International Journal of Reliability and Applications
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    • v.18 no.1
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    • pp.9-20
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    • 2017
  • In this paper, we consider a renewable repair-replacement warranty strategy with age-dependent minimal repair service and propose an optimal maintenance model during post-warranty period. Such model implements the repair time limit under warranty and follows with a certain form of system maintenance strategy when the warranty expires. The expected cost rate is investigated per unit time during the life period of the system as for the standard for optimality. Based on the cost design defined for each failure of the system, the expected cost rate is derived during the life period of the system, considering that a renewable minimal repair-replacement warranty strategy with the repair time limit is provided to the customer under warranty. When the warranty is finished, the maintenance of the system is the customer's responsibility. The life period of the system is defined and the expected cost rate is developed from the viewpoint of the customer's perspective. We obtain the optimal maintenance strategy during the maintenance period by minimizing such a cost rate after a warranty expires. Numerical examples using field data are shown to exemplify the application of the methodologies proposed in this paper.

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Self-Commissioning for Surface-Mounted Permanent Magnet Synchronous Motors

  • Urasaki Naomitsu;Senjyu Tomonobu;Uezato Katsumi
    • Proceedings of the KIPE Conference
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    • 2001.10a
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    • pp.331-335
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    • 2001
  • This paper presents the self-commissioning for surface-mounted permanent magnet synchronous motor. The proposed strategy executes three tests with a standard inverter drive system. To do this, synchronous d-q axes currents are appropriately controlled for each test. From the three tests, armature resistance, armature inductance, equivalent iron loss resistance, and emf coefficient are identified automatically. The validity of the proposed strategy is confirmed by experimental results.

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Design and Operation of Acceptance Control Chart Using Variable Acceptance Sampling Scheme Based on Operating Characteristics(OC) Curve (계량 규준형 샘플링 검사 스킴을 이용한 합격판정 관리도의 설계 및 운영)

  • Choi, Sung-Woon
    • Proceedings of the Safety Management and Science Conference
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    • 2008.04a
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    • pp.443-450
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    • 2008
  • This paper is to present design principle and operation strategy of acceptance control chart by the use of OC-Based sampling inspection for continuous data. The unified control limits for acceptance control chart when considering both APL(Acceptable Process Level) and RPL(Rejectable Process Level) are proposed. The control limits can be also extended to the acceptance control chart with unknown process standard deviation.

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