• Title/Summary/Keyword: Standard Indicator

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Preliminary Calculation of the Indicators of Sustainable Development for National Radioactive Waste Management Programs (국가 방사성폐기물 관리계획에 관한 지속가능 발전지표의 예비평가)

  • 정재학;박원재
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.1 no.1
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    • pp.1-10
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    • 2003
  • As a follow up to the Agenda 21's policy statement for safe management of radioactive waste adopted at Rio Conference held in 1992, the UN invited the LAEA to develop and implement indicators of sustainable development for the management of radioactive waste. The IAEA finalized the indicators in 2002, and is planning to calculate the member states' values of indicators in connection with operation of its Net-Enabled Waste Management Database system. In this paper, the basis for introducing the indicators into the radioactive waste management was analyzed, and calculation methodology and standard assessment procedure were simply depicted. In addition, a series of innate limitations in calculation and comparison of the indicators was analyzed. According to the proposed standard procedure, the indicators for a few major countries including Korea were calculated and compared, by use of each country's radioactive waste management framework and its practices. In addition, a series of measures increasing the values of the indicators was derived so as to enhance the sustainability of domestic radioactive waste management program.

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Acupuncture point locations for experimental animal studies in rats and mice (동물실험을 위한 흰쥐와 생쥐의 경혈위치)

  • Koo, Sung-Tae;Kim, Sun-Kwang;Kim, E-Hwa;Kim, Jae-Hyo;Youn, Dae-Hwan;Lee, Bong-Hyo;Chae, Youn-Byoung;Choi, Il-Hwan;Choi, Sun-Mi
    • Korean Journal of Acupuncture
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    • v.27 no.3
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    • pp.67-78
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    • 2010
  • Objectives : The aim of the study is to draw a consensus in acupuncture point locations (APLs) which are frequently used in experimental animal studies. Well-documented APL is needed not only for human but also for rodents because stimulation of precise point is very important factor in acupuncture. Methods : We organized a committee with experts to reach a consensus on the APLs in rat. The subject points were limited to 22 points used in the papers published at international peer-review journals. To describe point locations, we adopted the syntax of sentence used in the WHO standard acupuncture point locations. Results : Locations of 22 acupuncture points such as ST36, LI4, PC6, and SP6 were described in English with photographic illustrations. Interestingly, we found that ST36 had been inserted into 2 different locations in rodent. Under consideration of practical use, the location of ST36 point was described in 2 different ways. Conclusion : We hope that newly developed APLs would be a good indicator of acupuncture experiments in rats and mice.

An Improved, Reliable and Practical Kinetic Assay for the Detection of Prekallikrein Activator in Blood Products

  • Shin, In-Soo;Shim, Yun-Bo;Hong, Choong-Man;Koh, Hyun-Chul;Lee, Seok-Ho;Hong, Seung-Hwa
    • Archives of Pharmacal Research
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    • v.25 no.4
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    • pp.505-510
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    • 2002
  • An improved kinetic assay for prekallikrein activator (PKA), a potential vasodilator, has been developed to be used as an indicator for quality control during production of human albumin preparations. It consists of two reaction stages. In the first stage, PKA and prekallikrein are incubated at $37^{\circ}C$ for 45 min to allow the transformation into kallikrein. Kallikrein, a serine protease, catalyzes the splitting of p-nitroaniline (pNA) from its substrate H-D-Pro-Phe-Arg-pNA(S-2302). The rate at which pNA is released was measured spectrophotometrically at 405 nm. Prekallikrein, a substrate of PKA was purified by DEAE ion-exchange chromatography and the major potential variations in the assay were optimized; pH 8.0 and 150 mM sodium chloride were chosen to give a proper ionic strength. Reaction times in the range of 10 to 360 min provided linear dose-response curves. The concentration of prekallikrein was adjusted to fall between 1:1 and 1:3 dilutions to generate a linear standard calibration curve. Under the optimized conditions, reproducibility was checked. In a precision test, the coefficient of variation (CV) stayed within ${\pm}4%$ and the dose-response curve showed a good correlation (${r^2}=0.999$). An accuracy test with an international standard of PKA afforded a mean recovery of 97.5%.

Spray Pattern Analysis for a Centrifugal Fertilizer Distributor with Two Shutter Holes (두 개의 셔터 구멍이 적용된 원심식 비료 살포기의 살포패턴 분석)

  • Hwang, Seok-Joon;Park, Jeong-Hyeon;Lee, Ju-Yeon;Kim, Ki-Duck;Shin, Beom-Soo;Nam, Ju-Seok
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.18 no.10
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    • pp.8-19
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    • 2019
  • In this study, the spray pattern of a centrifugal fertilizer distributor with two shutter holes was analyzed and an effective driving width that satisfies proper spray uniformity was derived. The centrifugal fertilizer distributor was mounted on a tractor with a rated power of 23.7 kW and static and dynamic spray pattern tests were performed according to the standard procedure proposed by the American Society of Agricultural and Biological Engineers Standard ASAE S341.5. The height of the fertilizer distributor was 80 cm from the ground and the PTO (power take-off) shaft speed of the tractor was fixed at 540 rpm. The fertilizer scattered in space was collected using 275 evenly spaced collectors at shutter opening ratios of 25%, 50%, 75%, and 100%. The spray pattern was analyzed via the amount of sprayed fertilizer at each collector location and the coefficient of variation was used as an indicator of spray uniformity. Using the analyzed spray pattern, the effective driving width that satisfied less than 15% of the coefficient of variation was derived for different tractor driving patterns (race track mode, back and forth mode). From the results, spray uniformity increased as the shutter opening ratio decreased. The largest effective driving width was 8 m at a shutter opening ratio of 25% for both driving patterns.

Estimation of Forest Productive Area of Quercus acutissima and Quercus mongolica Using Site Environmental Variables (산림 입지토양 환경요인에 의한 상수리나무와 신갈나무의 적지추정)

  • Lee, Seung-Woo;Won, Hyung-Kyu;Shin, Man-Yong;Son, Young-Mo;Lee, Yoon-Young
    • Korean Journal of Soil Science and Fertilizer
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    • v.40 no.5
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    • pp.429-434
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    • 2007
  • This study was conducted to estimate site productivity of Quercus acutissima and Quercus mongolica by four forest climatic zones. We used site environmental variables (28 geographical and pedological factors) and site index as a site productivity indicator from nation-wide 23,315 stands. Based on multiple regression analysis between site index and major environmental variables, the best-fit multivaliate models were made by each species and forest climatic zone. Most of site index prediction models by species were regressed with seven to eight factors, including altitude, relief, soil depth, and soil moisture etc. For those models, three evaluation statistics such as mean difference, standard deviation of difference, and standard error of difference were applied to the test data set for the validation of the results. According to the evaluation statistics, it was found that the models by climatic zones and species fitted well to the test data set with relatively low bias and variation. Also having above middle of site index range, total area of productive sites for the two Quercus spp. estimated by those models would be about 6% of total forest area. Northern temperate forest zone and central temperate forest zone had more productive area than southern temperate forest zone and warm temperate forest zone. As a result, it was concluded that the regressive prediction with site environmental variables by climatic zones and species had enough estimation capability of forest site productivity.

Design the generation process of software quantitative evaluation index using ISO/IEC 25023 (ISO/IEC 25023을 활용한 소프트웨어의 정량적 평가지표 생성 프로세스 설계)

  • Kim, Suwook;Lee, Jongmin;Park, Yoohyun
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.23 no.5
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    • pp.508-515
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    • 2019
  • Although various quantitative indexes are used as criteria for deciding the success of software R & D projects, it is somewhat difficult to find which quantitative indexes are appropriate. In this paper, we propose a quantitative evaluation index generation process for software product development using ISO / IEC25023, which is used as a standard of software quality level, to provide criteria for quantitative evaluation index of software development. The proposed process consists of two stages. In the first step, quality characteristics and subcharacteristics of ISO / IEC25023 standard specification are derived and in the second stage, we derive an evaluation indicator guides that matches the quality characteristics and sub characteristics. The proposed quantitative evaluation index generation process is expected to be helpful for the selection of quantitative evaluation indexes according to the characteristics of software development projects.

VALIDATION AND UTILIZATION OF THE SKINTEXTM SYSTEM

  • Gordon, V.C.;Realica, B.;Tolstrup, K.;Puls, B.
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.17 no.1
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    • pp.64-80
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    • 1991
  • The SKINTEX Method is based on a two-compartment physico-chemical model which includes a Biomembrane Barrier in compartment one and an organized macromolecular matrix in compartment two. Test samples absorb onto or permeate through the keratin/collagen Biomembrane Barrier and then can interact with the organized macromolecular matrix. Changes in the integrity of the barrier release a dye indicator: Changes in the matrix can alter its transparency. The sum of these two responses is read spectrophotometrically at 470nm. An early investigation of 950 chemicals and formulations in the SKINTEX System produced results which were 89% concordance to in vivo Draize dermal irritation results obtained with 24-hour occluded application of test samples with-out abrasion and standard scoring. Alkaline materials were analyzed in a specialized SKINTEX AMA Protocol. In this early study, the model did not distinguish nonirritant test materials and formulation with PDII(Primary Dermal Irritation Index)in the range from 0 to 1.2, A High Sensitivity Assay Protocol(HSA)was developed to amplify the changes in both compartments of this model and provide more accurate calibration of these changes. A study of 60 low irritation test samples including cosmetics, household products, chemicals and petro-chemicals distinguished nonirritants with PDII $\leq$ 0.7 for 26 of 30 nonirritants. A second protocol was developed to evaluate the SKINTEX model predictability with respect to human irritation. The Human Response Assay (HRA )has been optimized based on differences in penetration and irritation responses in humans and rabbits. An additional 32 test materials with different mechanisms and degrees of dermal toxicity were evaluated by the HRA. These in vitro results were 86% concordant to human patch test results. In order to further evaluate this model, a Standard Chemical Labelling (SCL) Protocol was developed to optimize this system to predict Draize dermal irritation results after a 4-hour application of the test material. In a study of 52 chemicals including acids, bases, solvents, salts, surfactants and preservatives, the SCL results demonstrated 85% concordance to Draize results for a 4-hour application of test samples on non-abraded rabbit skin. The SKINTEX System, including three specialized protocols, provided results which demonstrated good correlation to the endpoint of dermal irritation in man and rabbits at different application times.

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A Study on Environmental Impact Assessment and Improvement Measures Around Construction Waste Intermediate Processing Sites in Rural Areas (농촌지역의 건설폐기물 중간처리 사업장 주변 환경 영향 평가 및 개선방안 연구)

  • Jang, Kyong-Pil;Kim, Byung-Yun
    • Journal of the Korean Institute of Rural Architecture
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    • v.26 no.2
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    • pp.65-72
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    • 2024
  • In order to analyze the impact of fine dust generated from a construction waste intermediate processing site on the surrounding areas, diverse types of samples were collected from inside the site and surrounding areas. The impact analysis results of samples are as follows. (1) Compared to the air quality management standards by the Ministry of Environment, the concentration of fine dust within the site was 30 to 46% for PM10 and 14 to 42% for PM2.5, which was not much different from the general air quality level. (2) It was found that PM10 within the site may have a partial effect on the air quality, but when the blocking facilities in the site, wheel washing facilities at vehicle entry and exit route, and sprinkler during working were maintained, the impact on the nearby area was not high. (3) In the case of PM2.5, its concentration was influenced more by the exhaust fumes from work vehicles than fine dust generated during construction waste processing. Since the PM2.5 concentrations in the site and surrounding area were not much different from the general air quality, there was little correlation with the work impact of construction waste intermediate processing sites. (4) Pb, an indicator of heavy metal components, was within 50ng/m3 in all three sites, which was 10% of the domestic management standard and equivalent to the general air quality level. The complaints from residents in nearby areas were filed using indicators based on visual and experiential information in their daily lives, so even if the survey results of environmental impact by the construction intermediate waste processing site are lower than the standard, nearby residents can feel it better than such numerical information. Therefore, specific activities to reduce find dusts should be continuously continued.

Chemotaxonomic Significance of Taxifolin-3-O-arabinopyranoside in Chinese Rhododendron genus

  • Tae Hee Kim;Hyeon Du Jang;Ye Ji Kim;Ye Eun Kwon;Sun Min Park;Min Seok Kim;Chan Ho Lee;Sun Eun Choi
    • Journal of Forest and Environmental Science
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    • v.40 no.2
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    • pp.123-140
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    • 2024
  • More than half of the global distribution of the Rhododendron genus is found in China, with over 74% being endemic species. However, there is still insufficient data to chemically classify the Rhododendron genus native to China. Therefore, in this study, a chemotaxonomic study was conducted to determine the presence of taxifolin-3-O-arabinopyranoside, a flavonoid compound, in the Rhododendron genus native to China. Forty-three species of Rhododendron native to China-20 from across China, 8 from Beijing, 6 from Yanbian, and 9 from Yunnan-were utilized in the experiment. Through HPLC analysis, the retention time was compared with that of taxifolin-3-O-arabinopyranoside, a standard compound, and quantitative analysis was conducted. As a result, taxifolin-3-O-arabinopyranoside was detected in 22 out of 43 the Chinese Rhododendron species. Afterwards, LC-MS/MS analysis was performed on the 22 species in which taxifolin-3-O-arabinopyranoside was detected to determine whether the molecular weight was consistent with the standard compound. Under negative conditions, it was confirmed that all samples exhibited the same molecular weight as taxifolin-3-O-arabinopyranoside, 435-436 m/z. The same compound was detected in more than half of the Rhododendron species used in the experiment, and taxifolin-3-O-arabinopyranoside was determined to be an indicator compound for Rhododendron species native to China. In addition, the possibility of using the above results as basic data for chemical classification of Chinese Rhododendron genus was confirmed.

Insulation Performance Evaluation through Insulation Test and Transient Heat Transfer Analysis of Cryogenic Common Bulkhead Propellant Tanks (극저온 공통격벽 추진제 탱크의 단열 시험과 과도 열전달 해석을 통한 단열 성능 평가)

  • Yeji Kim;Gyeong-Han Lee;Sang Min Choi;Sang-Woo Kim;Soo-Yong Lee
    • Journal of Aerospace System Engineering
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    • v.18 no.4
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    • pp.109-116
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    • 2024
  • The validity of the analysis results was confirmed based on the insulation test results, and the vaporization mass generated in the common bulkhead was calculated to evaluate the common bulkhead propellant tank's insulation performance. The analysis results were validated by comparing the transient heat transfer analysis with the insulation test results. A transient heat transfer analysis was subsequently conducted on the common bulkhead propellant tank, considering the internal heat conduction in the propellant tank and natural convection heat transfer due to the outside air. This analysis extracted the heat flux generated in the common bulkhead and quantified the vaporization mass, a key indicator of insulation performance. Consequently, the vaporization mass was calculated at 0.09 kg, below the insulation design standard of 0.12 kg for the common bulkhead propellant tank, confirming it meets the insulation performance standard.