• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2014년도 추계학술대회
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• pp.953-955
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• 2014

최근 차량 충돌 방지를 위한 다양한 기술이 상용화되고 있다. FMCW 기반의 레이더 시스템은 구현의 용이성으로 많은 상용차에서 전면 충돌 방지 시스템에 적용되고 있다. 측면 충돌 방지를 위한 BSD(Blind Spot Detection)와 차선변경 보조 시스템(LCA, Lane Change Assistant system)에서는 전방 레이더보다 인식거리가 줄어들고 갱신율이 낮아지므로 고속 FFT 등을 수행하는 신호처리부를 저가격으로 설계가 가능할 것이다. 본 연구에서는 TI사의 MCU인 F28335를 사용하여 근거리를 인식하는 신호처리부를 설계하였다. 이 MCU는 16채널 12bit ADC와 68KB RAM 및 512KB 플래시 메모리를 내장하고, 150MHz 부동소수점 연산을 지원하여 단일 칩으로 신호처리부의 구현이 가능하다. 구현된 시스템은 20m내외의 거리에 있는 장애물에 대하여 10Hz로 갱신이 가능하여 BSD를 위한 기본 기능이 확인되었다. 이러한 구현은 이전의 고가의 DSP나 FPGA를 사용하지 않고 15$이내의 단일 MCU와 간단한 아날로그 회로로 설계되어 저가격의 시스템으로 상용화가 가능할 것이다.

• Nuclear Engineering and Technology
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• 제54권6호
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• pp.2213-2220
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• 2022

The maximum dose delivery at the end of the beam range provides the main advantage of using proton therapy. The range of the proton beam, however, is subject to uncertainties, which limit the clinical benefits of proton therapy and, therefore, accurate in vivo verification of the beam range is desirable. For the beam range verification in spot scanning proton therapy, a prompt gamma detection system, called as gamma electron vertex imaging (GEVI) system, is under development and, in the present study, the performance of the GEVI system in spot scanning proton therapy was predicted with Geant4 Monte Carlo simulations in terms of shift detection sensitivity, accuracy and precision. The simulation results indicated that the GEVI system can detect the interfractional range shifts down to 1 mm shift for the cases considered in the present study. The results also showed that both the evaluated accuracy and precision were less than 1-2 mm, except for the scenarios where we consider all spots in the energy layer for a local shifting. It was very encouraging results that the accuracy and precision satisfied the smallest distal safety margin of the investigated beam energy (i.e., 4.88 mm for 134.9 MeV).

• 정보처리학회논문지B
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• 제15B권6호
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• pp.561-574
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• 2008

2차원 전기영동 영상 분석 프로그램의 반점 검출 단계는 영상 분할 알고리즘을 사용해서 겔 영상을 반점 영역으로 분할하고 각 반점 영역을 반점 형태 모형에 정합하여 다음 단계에 필요한 반점 정보를 정량화한다. 현재 영상 분할 알고리즘으로는 분수령 기법이 일반적으로 사용되며, 대표적인 반점 형태 모형으로는 가우스 모형, 확산 모형이 있다. 확산 모형이 가우스 모형보다 실제의 반점 형태에 좀 더 가깝기는 하지만, 반점 형태는 매우 다양하며 특히 x-축과 y-축에 대해서 비대칭적인 형태를 보인다. 반점이 비대칭적 형태인 이유는 2-DE 처리가 통상 이상적인 환경 하에서 이루어질 수 없기 때문에 단백질이 완전히 확산되지 못하기 때문으로 알려져 있다. 따라서 본 논문에서는 비대칭 확산 모형을 제안한다. 비대칭 확산 모형은 초기에는 단백질이 하나의 원으로부터 확산되지만, 시간이 흐름에 따라 x-축과 y-축에 대해서 비대칭적으로 확산된다고 가정한 모형이다. 실험으로서 19개의 겔 영상에 대해서 세 모형별로 반점 정합을 수행하고 세 모형의 비교를 위해서 SNR의 평균을 구하였다. 실험결과인 SNR의 평균은 가우스 모형이 14.22dB, 확산 모형이 20.72dB, 비대칭 확산 모형이 22.85dB이었다. 실험결과로써 비대칭 확산 모형이 가우스 모형과 확산 모형에 비해서 반점 정합에 보다 더 효율적이며 적합한 모형임을 확인하였다.

• Journal of Microbiology and Biotechnology
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• 제26권3호
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• pp.588-595
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• 2016

IFN-γ release assays (IGRAs) have been developed as viable alternative diagnostic tools for detecting latent tuberculosis infection (LTBI). A customized homogeneous sandwich luminescent oxygen channeling immunoassay (LOCI) was used to quantify IFN-γ levels in IGRAs. Samples were collected from healthy volunteers (n = 40) who were T-Spot-negative and T-Spot-positive patients (n = 32) at rest. Then the amount of IFN-γ in the supernatant of IGRAs was measured by LOCI. The results demonstrated a low background, and high sensitivity, specificity, accuracy, and reproducibility, and a short assay time (only 30 min) with LOCI for IFN-γ. The recovery range was 81.63-102.06%, the coefficients of variation were below 5%, and the limit of detection was 19.0 mIU/ml. Excellent agreement between LOCI IFN-γ and the T-SPOT.TB test was obtained (97.2% agreement, κ = 0.94). The LOCI IFN-γ concentrations were significantly higher in T-Spot-positive patients than in the healthy group (p < 0.001). Moreover, as observed for the comparative LOCI IFN-γ assay, IFN-γ concentrations were related to the numbers of T-SPOT.TB spots. We have established an in vitro blood test for LTBI diagnosis, defined as LOCI IFN-γ. A high level of agreement between the LOCI IFN-γ method and T-SPOT.TB assay was observed in clinical studies that showed the LOCI IFN-γ method could determine LTBI. This study shows acceptable performance characteristics of the LOCI IFN-γ assay to diagnose LTBI.

• 약학회지
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• 제3권1호
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• pp.45-47
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• 1957

A paper chromatographical method is studied to detect As and Sb from a mixed sample applying the principle of Gutzeit's. After spoting the mixed $AsH_3$ sample on the $AgNO_3$ band of paper strip (6 mm $\times$ 300 mm of Whatman No.52 or Toyo No.2 filter paper), the strip is developed by ascending method using N-HCl solution as a developing soluvent. The color spot detection of As and Sb is done by exposing the dried chromatogram to $H_2S$ stream. According to the experiments, the detectable minimum range of As is 3 micrograms and that of Sb is 15 micrograms. The yellow phosphorous interfers to the color spot detection of As and Sb, so that, previously the most of yellow phosphorous from the sample should be removed out.

• 한국정보컨버전스학회:학술대회논문집
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• 한국정보컨버전스학회 2008년도 International conference on information convergence
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• pp.113-116
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• 2008

In this paper we suggest two novel methods for an implementation of the spot detection phase in the 2-DE gel image analysis program. The one is the adaptive thresholding method for eliminating noises and the other is the asymmetric diffusion model for spot matching. Remained noises after the preprocessing phase cause the over-segmentation problem by the next segmentation phase. To identify and exclude the over-segmented background regions, il we use a fixed thresholding method that is choosing an intensity value for the threshold, the spots that are invisible by one's human eyes but mean very small amount proteins which have important role in the biological samples could be eliminated. Accordingly we suggest the adaptive thresholding method which comes from an idea that is got on statistical analysis for the prominences of the peaks. There are the Gaussian model and the diffusion model for the spot shape model. The diffusion model is the closer to the real spot shapes than the Gaussian model, but spots have very various and irregular shapes and especially asymmetric formation in x-coordinate and y-coordinate. The reason for irregularity of spot shape is that spots could not be diffused perfectly across gel medium because of the characteristics of 2-DE process. Accordingly we suggest the asymmetric diffusion model for modeling spot shapes. In this paper we present a brief explanation ol the two methods and experimental results.

• 대한화학회지
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• 제8권2호
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• pp.85-87
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• 1964

Alloxan에 의한 Amino acids의 spot test에 있어서, alloxan수용액에 lactose를 가해주면, alloxan 자신의 착색을 막을 수 있다. lactose를 포함하는 alloxan수용액은 매우 안정하여서, 실온에서 수 개월 동안 두어도 착색되지 않으며, lactose의 존재로 말미암아, alloxan과 amino acids와의 색반응은 조금도 영향을 받지 않았다. 이시약에 의한 amino acids의 spot test법은 ninhydrin에 의한 spot test보다 예민하고, 또 alloxan 또는 dimethylalloxan을 발색약으로 사용하는 paper chromatography법에 비해, proline (1 ${\gamma}$), hydroxyprolin (5 ${\gamma}$)를 확인할 수 있다는 장점을 가지고 있다.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 1996년도 춘계학술대회 논문집
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• pp.271-275
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• 1996

In this paper, an automatic spot inspection system has been developed for camera target lens using the computer aided vision system. The developed system comprises: light source, magnifying optics, vision camera, XY robot, and a PC. An efficient algotithm for the spot detection has been implemented, thus up tof ew micrometer size spots can be effectively identified in real time. The developed system has been fully interfaced with XY robot systenm, PLCs, thus the practical spot inspection system has been implemented. The system has been applied to a practical camera manufacturing process, and showed its efficiency.

• 대한수의학회지
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• 제42권2호
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• pp.269-275
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• 2002

The aim of this study was to investigate the usefulness and effectiveness of thermography in horse. Total 21 horses associated with locomotors, wound, and ophthalmic disease were investigated. Thermographically, the wannest area in normal limb was coronary band ($27.26^{\circ}C$), and carpus, metacarpus, fetlock, and pastern area were $26.64^{\circ}C$, $24.42^{\circ}C$, $23.64^{\circ}C$ and $23.06^{\circ}C$, respectively. The temperature($^{\circ}C$) of horses with lameness, swelling, nervous, ataxia was lower(cold spot) than surrounding tissue or symmetry area, and with heat, signs of inflammation was increased(hot spot). These results suggest that the thermography is useful for the early detection of locomotors, wound, and ophthalmic disease in horse and an excellent adjunct to clinical examination.

• 한국공작기계학회:학술대회논문집
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• 한국공작기계학회 2004년도 추계학술대회 논문집
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• pp.49-53
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• 2004

Thin spot welding is frequently used for industrial purpose, such as automobile and aerospace industries and household appliances due to its high performance. In these days, the systemization of welding process made it possible to produce more precise or smaller electric parts. And when it comes to welding of steel sheets, the size of nugget must be getting smaller. Therefore, welding conditions are limited to avoid defects, such as deformation, damage and weakening of joining area. In this research, thin spot welding establishes the welding conditions, and then the measurement of the nugget size by the nondestructive inspection has been conducted. As a result, the right estimation of the nugget size, the detection of corona bond near joining area, the selection of the optimum ultrasonic mode, and setup for ultrasonic inspection are studied. From the trustworthy solutions of the nugget size estimated by results of measurement, the optimum inspection conditions depending upon the width of welding parts are determined as well.