• Journal of Korean Neurosurgical Society
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• v.30 no.2
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• pp.156-162
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• 2001

Objective : The purpose of this study is to review our experience with spontaneous thalamic hemorrhage. Clinical outcome of patients was brought about by comparing stereotactic aspiration and conservative medical therapy. Methods : The study consists of seventy-three cases with spontaneous thalamic hemorrhage which were treated from the period of Jan. 1993 to Dec. 1999. Thirty-eighty patients were treated with computed tomography (CT) guided stereotactic aspiration and thirty-five patients were treated conservatively. We compared the factors affecting treatment and the factors are as follows : age & sex, conscious level on admission, hematoma volume, hematoma sites, presence of ventricular penetration. Results : The results in the thirty eight stereotactic aspirated cases for the 6 months from oneset are as follows : good recovery or moderate disability in 43%, severe disability in 32%, vegitative state in 11%, dead in 13% respectively. The clinical result was more favorable in stereotactic aspiration, with 11-30cc hematoma volume, extend to internal capsule of hematoma, poor conscious level on admission than conservative medical therapy. But age & sex, conscious level on admission, presence of ventricular penetration were not influential in the statistical outcome between stereotactic aspiration and conservative medical therapy. Conclusion : Treatment modality of spontaneous thalamic hemorrhage is still controversial. But stereotactic aspiration is more recommended for improvement therapeutic results than conservative treatment or open craniotomy in case of 11-30cc hematoma volume, extend to internal capsule of hematoma and poor conscious level on admission.

• Journal of Korean Neurosurgical Society
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• v.54 no.5
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• pp.431-433
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• 2013

Acute subdural hematoma is usually a neurological emergency that requires hematoma evacuation or close observation. However, spontaneous resolutions of an acute subdural hematoma without surgical interventions have been reported rarely. We report on a case who showed rapid resolution of an acute subdural hematoma with neurological improvement and review the relevant literatures.

• Journal of Agricultural Extension & Community Development
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• v.3 no.2
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• pp.219-232
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• 1996

The Crop Units and Agricultural Cooperatives is experiencing many difficulties with national and international environmental changes. For the developing of Crop Units and Agricultural Cooperatives, Crop Units and Agricultural Cooperatives make endeavor to lead members` spontaneous participation and the efficient communication between members, and to offer the efficient extension services and support activities for improvement of members` economic and social status.

• Transactions of the Korean Society of Mechanical Engineers
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• v.9 no.5
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• pp.627-637
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• 1985

The combustion process and the performance of a diesel engine are seriously affected by the ignition delay period of the fuel used. Some methods for improving the combustion process in the engine cylinder are to well match the strength of air swirl with the space of sprays in the cylinder, to blend an ignition improver in the fuel, to inject a small amount of auxiliary fuel prior to main injection and so on. Recently, the improvement of fuel economy and the reduction of exhaust smoke and NO have been successfully achieved by supplying diesel engines with emulsified fuel. However, it is very difficult to know real combustion mechanism under such special conditions, because of many factors affecting on the combustion process in practical reciprocating engine. In the present paper, the combustion processes of diesel fuel and emulsion fuel were tried to improve and to observe by making contact with various lean pre-mixtures in the hot air stream duct. This hot air stream method has an advantage that the spontaneous combustion process can be observed under a simplified condition.

• Journal of Microbiology and Biotechnology
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• v.32 no.6
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• pp.792-799
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• 2022

As a vital problem in reproductive health, recurrent spontaneous abortion (RSA) affects about 1% of women. We performed this study with an aim to explore the molecular mechanism of interleukin-23 (IL-23) and find optimal or effective methods to improve RSA. First, ELISA was applied to evaluate the expressions of IL-23 and its receptor in HTR-8/SVneo cells after IL-23 treatment. CCK-8, TUNEL, wound healing and transwell assays were employed to assess the proliferation, apoptosis, migration and invasion of HTR-8/SVneo cells, respectively. Additionally, the expressions of apoptosis-, migration-, epithelial-mesenchymal transition- (EMT-) and p38 MAPK signaling pathway-related proteins were measured by western blotting. To further investigate the relationship between IL-23 and p38 MAPK signaling pathway, HTR-8/SVneo cells were treated for 1 h with p38 MAPK inhibitor SB239063, followed by a series of cellular experiments on proliferation, apoptosis, migration and invasion, as aforementioned. The results showed that IL-23 and its receptors were greatly elevated in IL-23-treated HTR-8/SVneo cells. Additionally, IL-23 demonstrated suppressive effects on the proliferation, apoptosis, migration, invasion and EMT of IL-23-treated HTR-8/SVneo cells. More importantly, the molecular mechanism of IL-23 was revealed in this study; that is to say, IL-23 inhibited the proliferation, apoptosis, migration, invasion and EMT of IL-23-treated HTR-8/SVneo cells via activating p38 MAPK signaling pathway. In conclusion, IL-23 inhibits trophoblast proliferation, migration, and EMT via activating p38 MAPK signaling pathway, suggesting that IL-23 might be a novel target for the improvement of RSA.

• Microbiology and Biotechnology Letters
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• v.38 no.3
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• pp.235-243
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• 2010

For decades, traditional mutation breeding technologies using spontaneous mutation, chemicals, or conventional radiation sources have contributed greatly to the improvement of crops and microorganisms of agricultural and industrial importance. However, new mutagens that can generate more diverse mutation spectra with minimal damage to the original organism are always in need. In this regard, ion beam irradiation, including proton-, helium-, and heavier-charged particle irradiation, is considered to be superior to traditional radiation mutagenesis. In particular, it has been suggested that ion beams predominantly produce strand breaks that often lead to mutations, which is not a situation frequently observed in mutagenesis induced by gamma-ray exposure. In this review, we briefly describe the general principles and history of particle accelerators, and then introduce their successful application in ion beam technology for the improvement of crops and microbes. In particular, a 100-MeV proton beam accelerator currently under construction by the Proton Engineering Frontier Project (PEFP) is discussed. The PEFP accelerator will hopefully prompt the utilization of ion beam technology for strain improvement, as well as for use in nuclear physics, medical science, biology, space technology, radiation technology and basic sciences.

• Journal of Sasang Constitutional Medicine
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• v.14 no.2
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• pp.106-114
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• 2002

The etiology of spontaneous intracerebral hematoma is aneurysmal rupture, arteriovenous malfomation, brain rumor, blood dyscrasia, cerebral infaction, cerebra inflammatory vascular disease, hypertension, and unknown causes. And the primary intracerebral hematoma is caused by unknown causes including hypertension. The clinical diagnosis of intracerebral hematoma, size, location, ventricular penetration, and evolution of brain parenchyme by hemorrhage are confirmed by CT scan. The authors have experienced 1 case of spontaneous intracerebral hematoma confirmed by CT scan. We have diagnosed the patient as Soyangin and treated by east integrated therapy. We classified this case as Soyangin-liyoiljung(少陽人裏熱證) and prescribed Yangkyuksanhwatang' Jihwangbaekhotang Hyungbangsabaeksan to the principle of Cheongyangsangsung(淸陽上升). In the result, we had the improvement of the symptoms. This report discribed the process and contents about the way the patient was cured.

• The Journal of Internal Korean Medicine
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• v.42 no.2
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• pp.95-103
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• 2021

We report on a Soeumin patient with spontaneous sweating after a lung segmentectomy resulting from aspergillosis. During her inpatient stay, the patient received Soeumin Gwakhyangjunggi-san, Hwanggigyeji-tang, and Seungyangikgi-tang for herbal medication. She also received acupuncture, moxibustion, pharmacopuncture, and cupping therapy. A numeric rating scale (NRS) was used to assess the improvement of symptoms. Sweating was reduced, as reflected by an NRS change from 7 to 0, when the herbal medication changed from Soeumin Gwakhyangjunggi-san to Hwanggigyeji-tang. General weakness and chest discomfort were also relieved after using Hwanggigyeji-tang and Seungyangikgi-tang. These results suggest that Hwanggigyeji-tang and Seungyangikgi-tang are clinically effective for Soeumin patients who are appropriately diagnosed with yang collapse syndrome in the postoperative setting.

• The Journal of Korean Medicine
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• v.23 no.4
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• pp.196-202
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• 2002

Aphasia is frequent in stroke patients and most patients with aphasia exhibit spontaneous progressive improvement in language abilities over time, but few recover completely. Neurological variables, especially initial severity of aphasia and time post-onset, appear to have influence on improvement. Effect of speech therapy and pharmacotherapy has been studied and some drugs, like amphetamine are proved to be benefit for recovery of aphasia following stroke. But there has been few evidence to facilitate recovery from aphasia by acupuncture or herbal medication therapy. So we report two cases of aphasic stroke patients who treated by combination therapy of acupuncture, herbal medication(Cheongsinhaeo-tang) and speech therapy over 6 months and improved in language abilities. Further clinical studies will be needed to explore the effects of acupuncture and herbal medication therapy for aphasia. Researchers should examine the long term effect of these treatment, and whether it is more effective than speech therapy and western pharmacotherapy or not..

• Journal of Sasang Constitutional Medicine
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• v.34 no.4
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• pp.89-102
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• 2022

Objectives This study was aimed to report significant improvement of vestibular neuronitis treated with Cheongsimyeonja-tang. Methods The patient was treated with Sasang herbal medicine for vestibular neuronitis. Also acupuncture and pharmacopuncture were used to treat neck and shoulder pain. Numeral rating scale(NRS), Romberg test, Spontaneous nystagmus, Induced nystagmus and Head thrust test were used to observe changes of dizziness in vestibular neuronitis. Results and Conclusions After 41days of treatment, the patient showed improvement in NRS. Also, the patient's symptoms of nausea, dyspepsia, sleep disturbance were improved. This study shows that Cheongsimyeonja-tang might be effective in Taeumin patient's vestibular neuronitis.