• Archives of Pharmacal Research
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• 제22권2호
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• pp.189-193
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• 1999

Reversed-phase high-performance liquid chromatography/mass spectrometry (HPLC/MS) with an eletcrospray ionization (ESI) interface was applied to the identification of metabolites of IY81149 in the rat plasma. Fragments obtained using collision-induced dissociation (CID) in both positive and negative modes were utilized to elucidate the structure of metabolites. The eluent from the conventional HPLC column was split and directly introduced into an ESI-mass spectrometer for the identification of the structures. the CID technique allowed the sensitive identification of sulfonyl-IY81149 and hydroxy-IY81149 from the rat plasma.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제48권1호
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• pp.63-67
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• 2022

Controversies exist regarding the need for prophylactic extraction of mandibular third molars in patients who plan to undergo orthognathic surgery. An 18-year-old male patient was diagnosed with mandibular prognathism and maxillary retrognathism with mild facial asymmetry. He had a severely damaged mandibular first molar and a horizontally impacted third molar. After extraction of the first molar, the second molar was protracted into the first molar space, and the third molar erupted into the posterior line of occlusion. The orthognathic surgery involved clockwise rotation of the maxillomandibular complex as well as angle shaving and chin border trimming. Patients who are missing or have damaged mandibular molars should be monitored for eruption of third molars to replace the missing posterior tooth regardless of the timing of orthognathic surgery.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제36권4호
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• pp.154-160
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• 2014

Purpose: The efficiency of an anchor plate placed during orthognathic surgery via minimal presurgical orthodontic treatment was evaluated by analyzing the mandibular relapse rate and dental changes. Methods: The subjects included nine patients with Class III malocclusion who had bilateral sagittal split osteotomy at the Division of Oral and Maxillofacial Surgery, Department of Dentistry in Ajou University Hospital, after minimal presurgical orthodontic treatment. During orthognathic surgery, anchor plates were placed at both maxillary buttresses. The anchor plates were used to move maxillary teeth backward and for maximum anchorage of Class III elastics to minimize mandibular relapse during the postoperative orthodontic treatment. The lateral cephalometric X-ray was taken preoperatively (T0), postoperatively (T1), and one year after the surgery (T2). Seven measurements (distance from Pogonion to line Nasion-Nasion perpendicular [Pog-N Per.], angle of line B point-Nasion and Nasion-Sella [SNB], angle of line maxilla 1 root-maxilla 1 crown and Nasion-Sella [U1 to SN], distance from maxilla 1 crown to line A point-Nasion [U1 to NA], overbite, overjet, and interincisal angle) were taken. Measurements at T0 to T1 and T1 to T2 were compared and differences tested by standard statistical methods. Results: The mean skeletal change was posterior movement by $13.87{\pm}4.95mm$ based on pogonion from T0 to T1, and anterior movement by $1.54{\pm}2.18mm$ from T1 to T2, showing relapse of about 10.2%. There were significant changes from T0 to T1 for both Pog-N Per. and SNB (P<0.05). However, there were no statistically significant changes from T1 to T2 for both Pog-N Per. and SNB. U1 to NA that represents the anterior-posterior changes of maxillary incisor did not differ from T0 to T1, yet there was a significant change from T1 to T2 (P<0.05). Conclusion: This study found that the anchor plate minimizes mandibular relapse and moves the maxillary teeth backward during the postoperative orthodontic treatment. Thus, we conclude that the anchor plate is clinically very useful.

• Archives of Plastic Surgery
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• 제42권4호
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• pp.419-423
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• 2015

Background Orthognathic surgery is required in 25% to 35% of patients with a cleft lip and palate, for whom functional recovery and aesthetic improvement after surgery are important. The aim of this study was to examine maxillary and mandibular changes, along with concomitant soft tissue changes, in cleft patients who underwent LeFort I osteotomy and sagittal split ramus osteotomy (two-jaw surgery). Methods Twenty-eight cleft patients who underwent two-jaw surgery between August 2008 and November 2013 were included. Cephalometric analysis was conducted before and after surgery. Preoperative and postoperative measurements of the bone and soft tissue were compared. Results The mean horizontal advancement of the maxilla (point A) was 6.12 mm, while that of the mandible (point B) was -5.19 mm. The mean point A-nasion-point B angle was $-4.1^{\circ}$ before surgery, and increased to $2.5^{\circ}$ after surgery. The mean nasolabial angle was $72.7^{\circ}$ before surgery, and increased to $88.7^{\circ}$ after surgery. The mean minimal distance between Rickett's E-line and the upper lip was 6.52 mm before surgery and 1.81 mm after surgery. The ratio of soft tissue change to bone change was 0.55 between point A and point A' and 0.93 between point B and point B'. Conclusions Patients with cleft lip and palate who underwent two-jaw surgery showed optimal soft tissue changes. The position of the soft tissue (point A') was shifted by a distance equal to 55% of the change in the maxillary bone. Therefore, bone surgery without soft tissue correction can achieve good aesthetic results.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제28권2호
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• pp.126-131
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• 2002

Anatomical shape of the mandibular ramus, which includes the area from the rear of the mandibular second molar to the mandibular posterior border and from the mandibular sigmoid notch to the inferior mandibular border, must be carefully considered to perform orthognathic surgery. The locations of the lingula and mandibular foramen in medial side of mandibular ramus are one of the most important factors to decide the location of the horizontal medial osteotomy in sagittal split ramus osteotomy and to select the line of vertical osteotomy in intraoral vertical ramus osteotomy. Sixty-five different Korean human dry mandibles were surveyed. All mandible have permanent dentition including complete eruption of the mandibular second molar. The locations of the lingula and mandibular foramen in medial side of the ramus were identified and following results were obtained. Anterior ramal horizontal distance from lingula was $16.13{\pm}3.53mm(range:8.6{\sim}24.3mm)$, anterior ramal horizontal distance from mandibular foramen was $23.91{\pm}4.79mm(range: 14.1{\sim}39.7mm)$, horizontal width of mandibular foramen was $2.79{\pm}0.95mm(range:1.5{\sim}6.1mm)$, height of lingula was $10.51{\pm}3.84mm(range:3.1{\sim}22.4mm)$, vertical distance from sigmoid notch to lingula was $19.82{\pm}5.11mm(range:9.1{\sim}35.3mm)$. From this study, the result could be used to select the location of osteotomy lines and to decide amount of periosteal elevation to avoid injury of neurovascular bundle, and to accomplish the appropriate split in Korean patients in mandibular orthognathic surgery.

• 한국항해항만학회지
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• 제26권3호
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• pp.289-294
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• 2002

본 논문에서는 디지털 TV 중계기용 고출력 광대역의 3-Way 전력결합기를 설계.제작하였다. 대역폭 증가와 고출력을 동시에 이루기 위하여 Wilkinson 형태의 전력분배기를 채택하였다. 우선 Wilkinson 전력분배기를 균등(1 : 1) 및 비균등(2 : 1) 분배시켜, 동위상 4 포트 전력결합기를 시뮬레이션 하였다. 시뮬레이션 결과에 따라서 두께 120 mil인 유전체 기판을 사용하여 제작된 전력결합기는 디지털 TV 중계기 주파수 470~806 MHz 대역에서 삽입손실 -6.53dB 이하, 반사계수 -13dB 이하, 포트 간 분리도 -15 dB 이하, 출력 포트 간 위상차가 13$^{\circ}$이하의 특성을 보였다. 새롭게 만든 전력결합기는 회로에서의 고 임피던스로 인한 마이크로스트립 선로 폭의 한계와 고출력의 경우 선로간의 상호작용으로 인한 전력의 손실 및 협대역의 문제를 동시에 개선이 가능함을 알 수 있었다. 나아가서, 제작된 3-Way 결합기의 삽입손실, 반사계수, 포트간의 분리도 및 위상차가 디지털 TV 중계주파수 470~806 MHz에서 양호한 특성을 나타내는 것을 확인함으로써 고출력 및 광대역화가 실현가능하다는 것을 알 수 있었다.

• 한국수산과학회지
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• 제20권2호
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• pp.106-113
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• 1987

명태주낙어업에서 전적으로 수동에 의존하고 있는 투승작업과 장승작업 및 낚시를 정리하는 작업을 자동기계화 시키기 위해서, 유압으로 구동되는 자동미끼는 장치와 자동양승기 및 미끼제거장치와 낚시정리대를 개발하여, 그 작동 성능을 실험실과 해상에서 실험하였고, 또한 자동투승기에서 유압장치 동작특성과 자동양승기의 낚시 분리성능을 측정한 결과는 다음과 같다. 1. 유압 회로의 압력이 높아질수록 미끼를 이송하고 절단하는데 걸리는 시간은 짧아졌으나, 미끼 절단 후 절단날이 정지할때까지 진행되는 각도는 커졌다. 2. 미끼의 이송과 절단에 적절한 유압회로의 압력은 $13\~20kgf/cm^2$이고, 미끼꿰는 효율은 염장한 양미리를 미끼로 했을해 $90\%$정도였다. 3. 자동양승기의 낚시 분리성능은 양승속도나 아릿줄의 재료에 따른 영향은 거의 없었고, 평균 $95.5\%$를 나타내었다. 4. 해상실험에서는 자동투승장치의 내진성이 문제되었으나, 자동양승장치는 실험실에서의 실험과 차이없이 양호하게 작동하였다.

• 복식
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• 제65권3호
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• pp.62-75
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• 2015

The purpose of this study is to examine how fine art is received in fashion, and to contribute to the development of a creative fashion culture. In order to do this examination, this study focuses on the formative ideas of De Stijl which appeared in the early 20th century. In addition, this study presents examples of today's fashion that still reflects the formative ideas of De Stijl. The De stijl movement did not last for a long time, but it has had significant influence on modern art, and has been a source of inspiration to fashion designers since the Mondrian look was presented by Yves Saint Laurent in 1965. The study on the basis of De Stijl such as Neo-Plasticism of Piet Mondrian and Elementalism of Theo van Doesburg, has been conducted in this study. As a result, this study presents formative characteristics of the De Stijl group in fashion as follows: First, contemporary fashion designers have searched for proportion and thickness of lines and the side split using lines, a stylistic trait of an artist in the De Stijl group. Second, color scheme defined by the De Stijl group has been applied with modification to contemporary fashion. Modification and selective choice of the limited colors are for a contemporaneous style. Third, formative ideas of De Stijl, which strives to achieve the vision of Utopia, has turned up in contemporary fashion as a simple and minimal silhouette. Contemporary fashion has enhanced their aesthetic value by deriving not only a superficial expression but also plastic principle and philosophy from De stijl. It can be regarded as the fashion's ideal way to embrace style of art and it might be so described as a key to edifying artistic and creative attributes of fashion.

• Asian-Australasian Journal of Animal Sciences
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• 제22권12호
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• pp.1609-1613
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• 2009

The objective of this study was to estimate genetic parameters for racing performance traits of thoroughbredracehorses, using a total of 58,124 racing records of 4,200 horses at Gwacheon Racing Park collected from January 2002 to December 2006. This study measured start one furlong time, last three and last one furlong times, and the resulting furlong time averages were 14.2 seconds, 39.9 seconds and 13.9 seconds, respectively. Furlong time means a split time measured based on a 1/8-mile (or approximately 201 m) distance and finished time means total racing time measured from start position to finish line. In the shortest distance races of 1,000 m, the average last three and last one furlong time was fastest at 38.7 seconds and 13.6 seconds, respectively. The correlation between finished time and start one furlong time decreased as the race distance increased, and the same trend was recognized from the correlation between finished time and last three furlong time. In short distance races of 1,400 m or less, the starting ability was found to be an important trait. The average speed was highest at 56 km/h for a 1,000 m race and lowest at 53.2 km/h for a 1,700 m race. Heritabilities of the start one furlong time, the last three and last one furlong time were estimated to be 0.337, 0.245 and 0.210, respectively; and repeatabilities for them were 0.452, 0.353 and 0.309, respectively. Phenotypic and genetic correlations between the start and the last one furlong time were negative at -0.141 and -0.155, respectively.

• Asian Pacific Journal of Cancer Prevention
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• 제16권5호
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• pp.2061-2068
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• 2015

Background: Tumors are largely unable to metabolize ketone bodies for energy due to various deficiencies in one or both of the key mitochondrial enzymes, which may provide a rationale for therapeutic strategies that inhibit tumor growth by administration of a ketogenic diet with average protein but low in carbohydrates and high in fat. Materials and Methods: Thirty-six male BALB/C nude mice were injected subcutaneously with tumor cells of the colon cancer cell line HCT116. The animals were then randomly split into three feeding groups and fed either a ketogenic diet rich in omega-3 fatty acids and MCT (MKD group; n=12) or lard only (LKD group; n=12) or a standard diet (SD group; n=12) ad libitum. Experiments were ended upon attainment of the target tumor volume of $600mm^3$ to $700mm^3$. The three diets were compared for tumor growth and survival time (interval between tumor cell injection and attainment of target tumor volume). Results: The tumor growth in the MKD and LKD groups was significantly delayed compared to that in the SD group. Conclusions: Application of an unrestricted ketogenic diet delayed tumor growth in a mouse xenograft model. Further studies are needed to address the mechanism of this diet intervention and the impact on other tumor-relevant parameters such as invasion and metastasis.