• Clinical and Experimental Pediatrics
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• v.55 no.10
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• pp.383-387
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• 2012

Purpose: Although benign rolandic epilepsy (BRE) is a benign condition, it may be associated with a spectrum of behavioral, psychiatric, and cognitive disorders. This study aimed to assess the cognitive and other neuropsychological profiles of children with BRE. Methods: In total, 23 children with BRE were consecutively recruited. All children underwent sleep electroencephalography (EEG) and were assessed on a battery of comprehensive neuropsychological tests including the Korean versions of the Wechsler intelligence scale for children III, frontal executive neuropsychological test, rey complex figure test, Wisconsin card sorting test, attention deficit diagnostic scale, and child behavior checklist scale. Results: The study subjects included 13 boys and 10 girls aged $9.0{\pm}1.6$ years. Our subjects showed an average monthly seizure frequency of $0.9{\pm}0.7$, and a majority of them had focal seizures (70%). The spike index (frequency/min) was $4.1{\pm}5.3$ (right) and $13.1{\pm}15.9$ (left). Of the 23 subjects, 9 showed frequent spikes (>10/min) on the EEG. The subjects had normal cognitive and frontal executive functions, memory, and other neuropsychological sub-domain scores, even though 8 children (35%) showed some evidence of learning difficulties, attention deficits, and aggressive behavior. Conclusion: Our data have limited predictive value; however, these data demonstrate that although BRE appears to be benign at the onset, children with BRE might develop cognitive, behavioral, and other psychiatric disorders during the active phase of epilepsy, and these problems may even outlast the BRE. Therefore, we recommend scrupulous follow-up for children with BRE.

• Korean Journal of Plant Taxonomy
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• v.44 no.2
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• pp.88-90
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• 2014

An unrecorded species, Carex aequialta K$\ddot{u}$k. (Cyperaceae), was found in Yecheon-gun, Gyeongsangbuk-do and Jeju-si, Jeju-do. This species is distinguished from related taxa, C. maximowiczii Miq., C. suifunensis Kom., C. phacota Spreng., C. dimorpholepis Steud., C. shimidzensis Franch. and C. tegulata H. Lev. & Vaniot, by having suberect lateral spikes, awnless pistillate scales, short rhizomes and corymblike inflorescences. This taxon was named 'Mul-kko-ri-sa-cho' in Korean based on its external appearances and habitat. We provide its description, illustrations, photographs and the key of related taxa in Korea.

• International Journal of Oral Biology
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• v.31 no.2
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• pp.33-43
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• 2006

Dysplasia-associated seizure disorders are markedly resistant to pharmacological intervention. Relatively little research has been conducted studying the effects of antiepileptic drugs(AEDs)on seizure activity in a rat model of dysplasia. We have used rats exposed to methylazoxymethanol acetate(MAM) in utero, an animal model featuring nodular heterotopia, to investigate the effects of AEDs in the dysplastic brain. Pilocarpine was used to induce acute seizure in MAM-exposed and age-matched vehicle-injected control animals. Field potential recordings were used to monitor amplitude and numbers of population spikes, and paired pulse inhibition in response to stimulation of commissural pathway. Two commonly used AEDs were tested: diazepam 5, 2.5 mg/kg; phenytoin 40, 60 mg/kg. Diazepam(DZP) and phenytoin(PHT) reduced the amplitude of population spike in control and MAM-exposed rats. However, the amplitude of population spike was nearly eliminated in control rats as compared to the MAM-exposed rats. Pharmaco-resistance was tested by measuring seizure latencies in awake rats after pilocarpine administration(320 mg/kg, i.p.) with and without pretreatment with AEDs. Pre-treatment with PHT 60 mg prolonged seizure latency in control rats, but not in MAM-exposed animals. The main findings of this study are that acute seizures initiated in MAM-exposed rats are relatively resistant to standard AEDs assessed in vivo. These data suggest that animal model with cortical dysplasia can be used to screen the effects of potential AEDs.

• Korean Journal of Materials Research
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• v.10 no.11
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• pp.738-741
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• 2000

Univorm epitaxial $CoSi_2$layers have been grown in situ on a (100) Si substrate at temperatures near$ 600^{\circ}C$ by reactive chemical vapor deposition of cyclopentadienyl dicarbonyl cobalt, (Co(η(sup)5-C(sub)5H(sub)5) ($CO_2$). The growth kinetics of an epitaxial $CoSi_2$layer on al Si(100) substrate was investigated at temperatures ranging from 575 to $650^{\circ}C$. In initial deposition stage, plate-like discrete $CoSi_2$spikes were nucleated along the <111> directions in (100) Si substrate with a twinned structure. The discrete $CoSi_2$plates with both {111} and (100) planes grew into an epitaxial layer with a flat interface on (100) Si. For epitaxial $CoSi_2$growth on (100) Si, the activation energy of the parabolic growth was found to be 2.82 eV. The growth rate seems to be controlled by the diffusion of Co through the $CoSi_2$layer.

• The Journal of the Korea institute of electronic communication sciences
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• v.13 no.5
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• pp.1117-1124
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• 2018

Contrast enhancement plays an important role in various computer vision systems, since their usability can be improved with visibility enhancement of the images affected by weather and lighting conditions. This paper introduces a histogram modification algorithm that reflects the properties of original images in order to eliminate the saturation effect and washed-out of image details due to the over-enhancement. Our method modifies the original histogram so that an additive term fill histogram pits and the gamma correction suppresses histogram spikes. The parameters for the additive term and gamma correction are adjusted automatically according to statistical properties of the images. Experimental results for various low contrast and hazy images demonstrate that the proposed contrast enhancement improves visibility and reduces haze components effectively, while preserving the characteristics of original images, than the conventional methods.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.27 no.3
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• pp.238-242
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• 1982

The growth of spike, internode and leaf sheath in winter wheat(Tritican vulgale Vill.) was investigated by measuring them 10 times from April 15 to May 30, with 5 days intervals, in 1980. The variety used was Glumil(Suweon #215) which was newly developed at Wheat and Barley Research Institute in Suweon, Korea. During the periods investigated, the spike elongated from 0.6cm to 8.3cm. The spike began to elongate rapidly from 20 days before heading (April 25) and finished nearly off the elongation at 5 days before heading (May 10). The length of the spike showed highly significant correlation with that of 3rd internode ($r=0.974^{***}$), and. with that of first leaf sheath($r=0.954^{***}$) from the top of wheat plant. Correlation between the length of the 3rd internode and that of the first leaf sheath was also very high($r=0.995^{***}$). A major elongation of the spike occurred concurrently with the elongation of the third internode and with that of the first leaf sheath.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.26 no.4
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• pp.293-297
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• 1981

An attempt has been made to determine the optimum size of sampling unit and the number of samples for a given precision in wheat, using the data collected from the various experiments in 1979/80. It was found that the coefficients of variation for number of spikes except the case of high-ridge broadcasting by 8HP rotarized seeder are in the same order of those for yield of wheat, and the regression coefficients associated with the coefficients of variation and the size of sampling unit were significant at 1% level of type I error. A wide range of variation in the size of sampling unit was observed for different methods of seeding, indicating the proper sizes of sampling units for 40cm \times 18cm, 60cm \times 18cm, 20cm \times 5cm, 120cm \times 90cm to be 0.40$m^2$, 0.17$m^2$, , 0.11$m^2$, , 0.55$m^2$, , respectively. The variance component for the experimental error was not physically possible to estimate due probably to high variability among the sampling units. The number of the sampling units per plot for a given precision of CV=12% was estimated to be one in an experiment with 4 replicates.

• The Korean Journal of Physiology and Pharmacology
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• v.10 no.5
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• pp.235-242
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• 2006

Cortical malformation-associated epileptic seizures are resistant to conventional anticonvulsant drugs. Relatively little research has been conducted on the effects of antiepileptic drugs (AEDs) on seizure activity in a rat model of dysplasia. We have used rats exposed to methylazoxymethanol acetate (MAM) in utero, an animal model featuring nodular heterotopia, to investigate the effects of ethosuximide (ETX) in the dysplastic brain. Pilocarpine was used to induce acute seizure in MAM-exposed and age-matched vehicle-injected control animals. Field potential recordings were used to monitor the amplitude and number of population spikes, and paired pulse inhibition in response to stimulation of the commissural pathway. Pharmaco-resistance was tested by measuring seizure latencies after pilocarpine administration (320 mg/kg, Lp.) with and without pre-treatment with ETX. Pre-treatment with 300 mg of ETX significantly prolonged the latency to the status epilepticus (SE) in both control and MAM-treated groups. Pre-treatment with ETX 100mg and ETX 200 mg had little effect in MAMexposed rats. However, ETX 200 mg prolonged the latency to the SE in control groups. Spontaneous field potential and secondary after-discharges were higher for MAM-treated rat in comparison with control rats injects with ETX. The main findings of this study are that acute seizures initiated in MAM-exposed rats are relatively resistant to standard ETX assessed in vivo. These data suggest that ETX do not prolong seizure latencies in MAM-rats exposed to pilocarpine.

• Restorative Dentistry and Endodontics
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• v.20 no.2
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• pp.527-537
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• 1995

The effect of calcitonin gene-related peptide (CGRP), substance P (SP) and electrical stimulation of the tooth on the intradental nerve activtiy (INA) was investigated in anesthetized cats. The INA was recorded from single pulp nerve units dissected from the inferior alveolar nerve under stereomicroscope. The INA elicited by 3 minute application of 4M NaCl in deep dentinal cavity was compared before and after stimulation at 10 minute intervals. The magnitude of INA was calculated as the total number of nerve impulses produced in given period, and the changes of INA are expressed as % of control INA. The results obtained were as follows. 1. 16 single pulp nerve units were classified as 14 $A{\delta}$-fibers (3.4~19.4m/sec) and 2-fibers (1.5~1.7m/sec) according to the conduction velocity. 2. 4M NaCl evoked an irregular bursts of spikes which continued until washing out. Isotonic saline did not affect INA to subsequent applications of the hypertonic NaCl solution (P>0.05). 3. Local application of CGRP ($200{\mu}g$/ml) in deep dentinal cavity reduced the INA induced by 4M NaCl in $A{\delta}$-fiber units (P<0.01) and some units of those responded to CGRP during application. 4. Local application of SP ($100{\mu}g$/ml) in deep dentinal cavity reduced the INA induced by 4M NaCl in AS-fiber units (p<0.05), but increased the INA in C-fiber unit coincided with large reduction of the INA of $A{\delta}$-fiber units. 5. Monopolar electrical stimulation applied to the crown at intensities high enough to excite C-fibers (12V, 5ms, 10Hz, 10~30min) decreased the INA in $A{\delta}$-fiber units (P<0.01) and systemic pretreatment with phenoxybenzamine (3mg/kg, i.v.) enhanced this inhibitory effect (P<0.01). On the contrary, electrical stimulation increased the INA in C-fiber unit.

• Transactions on Electrical and Electronic Materials
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• v.18 no.3
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• pp.125-128
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• 2017

This study is on how ohmic area etching affects the buffer breakdown voltage of AlGaN/GaN HEMT. The surface morphology of the ohmic metal can be improved by whole etching on the ohmic area. The buffer breakdown voltages of the samples with whole etching on the ohmic area were improved by the suppression of the metal spikes formed under the ohmic contact regions during high-temperature annealing. The samples with selective etching on the ohmic area were investigated for comparison. In addition, the buffer leakage currents were measured on the different radii of the wafer, and the uniformity of the buffer leakage currents on the wafer were investigated by PL mapping measurement.