Detecting probable Alzheimer's disease (AD) at an early stage is crucial in slowing the progression of the disease and initiating drug therapy for more effective symptom management. Therefore, this study aimed to identify linguistic features that allow us to distinguish between patients with AD and normal controls. This paper reports on characteristics of spontaneous speech in subjects in three stages of AD (questionable, mild, moderate) compared with education- and age-matched normal controls. Four components of speech were measured in Korean native speakers with AD and normal aging: speech tempo, hesitation (measured in seconds), rate of articulation errors, and rate of grammatical errors. The results revealed significant differences in most of these speech components among the four groups, including significant differences between normal controls and the questionable AD group in the areas of speech tempo and rate of grammatical errors. Phonological? articulatory ability was preserved in questionable AD, and grammatical ability was preserved in questionable and mild AD. Subjects with moderate AD were severely impaired in grammatical ability. Prospective assessments of spontaneous speech skills using a dialogue and picture-description task are useful in detecting the subtle, spontaneous speech impairments that AD causes even in its early stage.
The purpose of this study was to develop a smartphone based voice therapy program for patients with voice disorders. Contents of voice therapy were collected through analysis of mobile contents related to voice therapy in Korea, experts and users' demand survey, and the program was developed using Android Studio. Content needed for voice therapy was collected through analysis of mobile contents related to voice therapy. The user satisfaction evaluation for application was conducted for five patient with functional voice disorders. The results showed that the mobile contents related to voice therapy in Korea were mostly related to breathing, followed by voice and singing, but only 13 applications were practically practiced for voice therapy. Expert and user demand surveys showed that the patients and therapists both had a high need for content that could provide voice training in places other than the treatment room. Based on this analysis, 'Home Voice Trainer', an smartphone based voice therapy program, was developed. Home Voice Trainer is an application for voice therapy and management based on Android smartphones. It is designed to train voice therapy activities at home that have been trained offline. In addition, the records of voice training of patients were managed online so that patients can maintain voice improvement through continuous voice consulting even after the end of voice therapy. User evaluations show that patients are satisfied with the difficulty and content of voice therapy programs provided by home voice trainers, but lack of a portion of user interface, such as the portion of home button and interface between screens. Further study suggests the clinical application of home voice trainer to the patients with voice disorders. It is expected that the development study and the clinical application of smart contents related to voice therapy will be actively conducted.
The current study was conducted to examine the temporal and spatial activation sequences related to morphosyntactic, semantic and orthographic-lexical sentences, focusing on the morphological-orthographic and lexical-semantic deviation processes in Korean language processing. The Event-related Potentials (ERPs) of 15 healthy students were adopted to explore the processing of head-final critical words in a sentential plausibility task. Specifically, it was examined whether the ERP-pattern to orthographic-lexical violation might show linear precedence over other processes, or the presence of additivity across combined processing components. For the morphosyntactic violation, fronto-central LAN followed by P600 was found, while semantic violation elicited N400, as expected. Activation of P600 was distributed in the left frontal and central sites, while N400 appeared even in frontal sites other than the centro-parietal areas. Most importantly, the orthographic-lexical violation process revealed by earlier N2 with fronto-central activity was shown to be complexes of morphological and semantic functions from the same critical word. The present study suggests that there is a linear precedence over the morphological deviation and its lexical semantic processing based on the immediate possibility of lexical information, followed by sentential semantics. Finally, late syntactic integration processes were completed, showing different topographic activation in order of importance of ongoing sentential information.
Ha, Jeong-been;Lee, Su-jung;Yang, Ji-soo;Lew, Jae-hwan
The Journal of Internal Korean Medicine
/
v.42
no.3
/
pp.323-339
/
2021
Objectives: This study investigates the effect of electro-acupuncture on aphasia after stroke. Methods: A search of OASIS, NDSL, PubMed, Cochrane, and CNKI was executed between 4 January 2021 and 4 February 2021, with no limitation on publication year. Extraction and selection from the studies were made by 3 authors. The quality of the studies was evaluated using Cochrane's risk of bias (RoB) tool. Results: 10 studies met the selection criteria. As the treatment site for electro-acupuncture, GV20 (Baihui) was used the most. In all studies, the region located on the head was used for treatment without distinguishing between acupoints and areas of scalp acupuncture, and the stimulation was organized into 3 conditions: speed, intensity, and time. The outcome indicators used before and after treatment focused on the evaluation of language function and the degree of aphasia. The results showed that using electro-acupuncture with speech rehabilitation therapy for aphasia after stroke was more effective than using speech rehabilitation therapy alone. Conclusions: In this review, electro-acupuncture for aphasia after stroke was found to have a significant effect compared to the previous treatment alone. However, because of limitations, information was not reliable enough. Additional research is needed to produce more objective evidence.
Journal of Korean Academy of Medicine & Therapy Science
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v.10
no.2
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pp.39-45
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2018
Objective: The aimes of this study is to analyze the effects of presbycusis on the quality of life. Method: 47-elderly were participated. The participants were divided into the suspected hearing impaired group (N=18) and the within normal limits (WNL) group (N=29). One-way ANOVA was performed to determine the association between the HHIE and WHOQOL-BREF scores by age group, and independent t-test was carried out to analyze the inter-group relations. Results: The scores in WHOQOL-BREF differed significantly by age group (p=.011): people in their sixties scored $3.7{\pm}.62$, those in their seventies $3.3{\pm}.56$, and those in their eighties $2.8{\pm}.60$, with significant differences observed. There were statistically significant inter-group differences (p=.000), with significant differences observed. Conclusion: The quality of life of the elderly were lowered depending on age and hearing impairment.
Kim, Su-bin;Kim, Kyung-mook;Suh, Won-joo;Mun, Sang-kwan;Jung, Woo-sang;Kwon, Seung-won;Cho, Ki-ho
The Journal of Internal Korean Medicine
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v.39
no.2
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pp.139-146
/
2018
Objective: The purpose of this clinical study is to report the effect of Banhahoobak-tang in the case of a 57-year-old woman with multiple cerebral infarction causing dysphagia and dysarthria diagnosed as pseudobulbar palsy. Methods: A patient was treated with Korean medicine, including herbal medication, acupuncture, and language therapy. We focused on the effect of Banhahoobak-tang by evaluating improvements in symptoms by examining times of aspiration and changes in Speech Mechanism Screening Test scores. Results: After three months of Korean medicine treatment and language therapy, there was improvement in the patient's symptoms, including dysphagia and dysarthria. Conclusions: This study suggests that Korean medicine treatment could be effective for improving the symptoms of pseudobulbar palsy in patients. Specifically, herbal medicine (Banhahoobak-tang) could be an effective choice for treating dysphagia.
Journal of the Korean Academy of Child and Adolescent Psychiatry
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v.6
no.1
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pp.74-89
/
1995
Selective mutism is a childhood condition defined by persisten failure to speak in specific social situation when speaking is expected, dispite preserved ability to comprehend spoken language and speak. Present study is to investigate clinical characteristics, treatment method and outcome of 23 children who were diagnosed as selective mutism by DSM-IV criteria at the child psychiatry ouptatient department of SNUH. The results were as follows : 1) The Sex ratio was 1: 4.8, female dominant Mear age of onset was 33 years old and mean age of first referral was 7.7 years old. 2) 22% of subjects had perinatal problem such as low birth weight, preterm birth, 26% of the subjects have history of delayed language development. There are subjects who had been separated with mam caretaker before 3 years old(26%) and who experienced physical or psychological trauma before 3 years old(26%). A few subjects had enurests(30%) and encoprests(4%). 3) Many subjects(65%) had symbiotic relationship with their mother. These families consist of dominant, verbally aggressive mother and passive father. Parents of 39% of all subjects were judged to have definite psychopathology(social phobic, depression, hysterical trait or alcohol problem) 26% of all subject, were reported physically abused. 4) The personality trait of the subjects were frequently described as follows(in order of frequency) ; Shy(100%), anxious(83%), stubborn(83%)m rigid and tense posture(78%), immature(65%) overdependent(65%), irritable(52%), manipulative(39%), depressive(39%). 5) The mean performance IQ of 16 subjects by KEDI-WISC was 88.3 Among them, the subjects with IQ below 69 were seven and those with IQ above 70 were nine. When comparing these two group(Mental retardation group vs Normal IQ group), we could find some difference in language development, personality trait, family dynamics and treatment outcome. 6) Among several treatment methods for selective mutism, play therapy was the most frequently used method(65%). Other commonly used treatment methods were pharmacotherapy(21%), behavioral therapy(8%), combined therapy(play therapy+pharmacotherapy+family therapy+behavioral therapy)(12%), 7) Regarding the outcome of treatment 8.6% was evaluated as Excellent, 30.4% as Good, 52% as Fair, 8.7% as Poor at the tinic of treatment. At follow up interview 21.7% was evaluated Excellent, 13% as Good, 21.7% as Fair, 34.8% as Poor. 8) We classified all subjects by Havden's 4 subtype. Symbiotic mutism was most common(65%) and other subtypes are Speech phobic mutism(8.6), Reactive mutism(13%) and Passive-aggressive mutism(30%).
Journal of The Korean Society of Integrative Medicine
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v.9
no.4
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pp.167-181
/
2021
Purpose : This study was conducted to investigate whether phonetic complexity affected the type and frequency of articulation errors and the acoustic duration of consonants and words produced by children with functional articulation and phonological disorders. Methods : The participants in this study were 20 children with functional articulation and phonological disorders and 20 children without such disorders who were between 3 years 7 months old and 4 years 11 months old. The participants were asked to name what they saw in pictures and their responses were recorded. The types and frequencies of articulation errors and the acoustic duration of words were analyzed and words were categorized as being of either 'high' or 'low' phonetic complexity. The acoustic duration of initial and final consonants and vowels following initial consonants were compared between the groups according to articulatory complexity. Results : Children with functional articulation and phonological disorders produced articulation errors more frequently when saying high complexity words and had longer word duration when saying low-complexity words than children without such disorders. There was no major difference in initial and final consonant duration between the groups. but the main effect of articulatory complexity on the duration of both consonants was significant. Conclusion : These results suggest that the articulatory-phonic structure of words influences the speech motor control ability of children with functional articulation and phonological disorders. When articulating consonants, children with functional articulation and phonological disorders had speech motor control ability similar to that of children without such disorders.
This study aims to acoustically analyze Korean language characteristics and convert these findings into musical elements, providing foundational data for evidence-based music-language rehabilitation. We collected voice data from thirty men and thirty women aged 19-25, each providing six-syllable prosodic units composed of two accentual phrases, including both declarative and interrogative sentences. Analyzing this data with Praat, we extracted syllabic acoustic properties and conducted statistical analyses based on acoustic properties, sentence type, gender, and particle presence. Significant differences were found in syllable frequency and duration based on accentual phrases and prosodic units (p < .001), with interrogative showing higher frequencies and declaratives longer durations (p < .001). Female frequencies were significantly higher than males' (p < .001), with longer durations observed (p < .001). Particle syllables also showed significantly stronger intensities (p < .001). Finally, we presented melodies converted from these acoustic properties into musical scores based on pitch, duration, and accent. The insights from this analysis of six-syllable Korean sentences will guide further research on developing a system for melodizing large-scale Korean speech data, expected to be crucial in music-based language rehabilitation.
The present study was conducted to investigate the influences of emotion priming and the number of negation words on the task of sentential predicate reasoning in groups with or without anxiety symptoms. 3 types of primed emotions and 2 types of stimulus and 3 conditions of negation words were used as a within-subject variable. The subjects were instructed to make facial expressions that match the directions, and were asked to choose the correct answer from the given examples. Mixed repeated measured ANOVA analyses on reaction time first showed main effects for the variables of emotion, stimulus, number of negation words and anxiety level, and the interaction effects for the negation words x anxiety combination. These results are presumably suggested to reflect that externally intervening emotion works on language comprehension in a way that anxiety could delay task processing speed regardless of the emotion and stimulus type, meanwhile the number of negation words can slower language processing only in a anxiety group. Implications and limitations were discussed for the future work.
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