• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.45 no.4
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• pp.225-229
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• 2019

Individuals with human immunodeficiency virus (HIV) infection present with unique intraoral manifestations of various neoplasms. Intraoral HIV-associated Burkitt's lymphoma is a rare presentation, especially in patients of Indian origin and may present as an initial sign of HIV. The objective of this paper is to report a rare case of Burkitt's lymphoma in an HIV-positive Indian patient along with a special emphasis on differential diagnosis. A 30-year-old Indian female presented with a solitary, well-defined, exophytic mass extending anteroposteriorly and buccolingually from the 35th to 38th regions with no evidence of intraosseous extension. An incisional biopsy was performed, and histopathology showed sheets of neoplastic lymphoid cells with numerous tingible body macrophages with clear cytoplasm, presenting a starry sky appearance, suggesting a diagnosis of BL. The tumor cells were positive for CD10, CD20, c-myc, and Epstein-Barr virus, with a nearly 100% Ki-67 proliferative index. The patient tested positive for HIV. This report indicates the importance of immunohistochemical analysis to differentiate Burkitt's lymphoma from other similar lesions like diffuse large B-cell lymphoma. Thorough knowledge of the clinical presentation, etiopathogenesis, histopathology, and immunoprofile of intraoral HIV-associated Burkitt's lymphoma is essential among clinicians and pathologists.

• Journal of Periodontal and Implant Science
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• v.42 no.3
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• pp.95-104
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• 2012

Purpose: The purpose of this study was to determine whether increasing the Ti6Al4V surface oxide negative charge through heat ($600^{\circ}C$) or radiofrequency plasma glow discharge (RFGD) pretreatment, with or without a subsequent coating with fibronectin, stimulated osteoblast gene marker expression in the MC3T3 osteoprogenitor cell line. Methods: Quantitative real-time polymerase chain reaction was used to measure changes over time in the mRNA levels for osteoblast gene markers, including alkaline phosphatase, bone sialoprotein, collagen type I (${\alpha}1$), osteocalcin, osteopontin and parathyroid hormone-related peptide (PTH-rP), and the osteoblast precursor genes Runx2 and osterix. Results: Osteoprogenitors began to differentiate earlier on disks that were pretreated with heat or RFGD. The pretreatments increased gene marker expression in the absence of a fibronectin coating. However, pretreatments increased osteoblast gene expression for fibronectin-coated disks more than uncoated disks, suggesting a surface oxide-mediated specific enhancement of fibronectin's bioactivity. Heat pretreatment had greater effects on the mRNA expression of genes for PTH-rP, alkaline phosphatase and osteocalcin while RFGD pretreatment had greater effects on osteopontin and bone sialoprotein gene expression. Conclusions: The results suggest that heat and RFGD pretreatments of the Ti6Al4V surface oxide stimulated osteoblast differentiation through an enhancement of (a) coated fibronectin's bioactivity and (b) the bioactivities of other serum or matrix proteins. The quantitative differences in the effects of the two pretreatments on osteoblast gene marker expression may have arisen from the unique physico-chemical characteristics of each resultant oxide surface. Therefore, engineering the Ti6Al4V surface oxide to become more negatively charged can be used to accelerate osteoblast differentiation through fibronectin-dependent and independent mechanisms.

• Journal of The Korea Institute of Healthcare Architecture
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• v.12 no.3
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• pp.27-34
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• 2006

Planning for the space of the Media Medical Department requires the details about the efficiency of the equipment and the operation in professional sector. For that, as designing, it is necessary to keep communicating with the experts on the technology and the officials from the company producing the equipment. One of the common concerns is not only how to insure enough room for the future extension and the upgrade of the equipment, as concerning the scale of the hospital, but the plan to cover movie cameras. As technology has been developed, despite the fact that machinery tend to be small, it can be possible to require continuously about the concerns of the scale because the camera taking body-picture tend to be much bigger and more complicated than before. Currently used diagnostic media techniques are divided by the method and the feature of the equipment such as Diagnostic X-ray, Ultrasound, CT, MRI, Angiography. The general and special photographing units which are used more than the other diagnostic parts, must be planned not for experiencing any inconvenience and unnecessary risks for the patients and must accept technical requirements. Also, it must be designed not to be seen as a clinic zone, as concerning the psychological stability of the patients. However, study of the general and special photographing units among the domestic general hospitals is insufficient. Also, as there is shortage of the material considering the development of the equipment, when planning, it's involving a lot of difficulties. Thus, this study has got a purpose on giving the basic material which is essential for further study, as suggesting the planning guidelines and the alternative plans for the general and special photographing units in a general hospital.

• The Korean Journal of Health Service Management
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• v.9 no.4
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• pp.13-32
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• 2015

Objectives : This study explored ways to identify factors that have competitive advantages and achieve high performance by investigating the influence of competence and competitive strategy on the performance and moderating effect of the business environment within special hospitals. Methods : A total of 80 specialized hospitals participated in the study. A multiple regression analysis was carried out by configuring sub-factors for each factor, and a hierarchical regression analysis was conducted with interaction terms as independent variables. Results : Among the competence factors of special hospitals, the competence of hospital staff and business management had a significantly positive (+) effect on the internal performance, and the competence of the marketing management had a significantly positive (+) effect on the external performance. Conclusions : The findings of this study suggest that in the rapidly changing health care environment, special hospitals should select and focus on competitive strategies and competency factors required to ensure competitiveness and achieve high performance, and based on this, need to seek integrated strategic management measures.

• KIEAE Journal
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• v.4 no.3
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• pp.187-194
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• 2004

In many other buildings, hospital is very important because of its function and purpose. A proper building service systems including heating, cooling, ventilation and plumbing systems is required in hospial. Besides, a special systems like medical gas, vacuum cleaning systems are required to prevent contamination as well as cure a patient in hospital. Ventilation is very important method to keep the indoor pressure and clean class. There are some specific rooms to consider clean class and indoor pressure in the general hospital. In this article, specific rooms were set to operating room, laboratory, ICU, isolation unit, and sterilizer room. In this case study, design factors of ventilation system, including air changes of OA and TA, indoor pressure, clean class, filter, and material of system, of specific rooms in hospital were proposed through a literature research and a design examples review.

• Journal of Chest Surgery
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• v.21 no.1
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• pp.82-86
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• 1988

Tetralogy of Fallot with subarterial ventricular septal defect is known to be relatively common in the Far East. Among the 140 consecutive patients who underwent repair for tetralogy, 15 [10,7@] had this variant form of tetralogy. Though the degree of pulmonic stenosis seems only mild or moderately severe because of the absence of infundibular septum and relatively large size of pulmonary arteries in this type of tetralogy, it has a special surgical implication that a patch widening of the right ventriculotomy is necessary in every case to avoid the postoperative subpulmonic stenosis. A morphological and surgical features of tetralogy with subarterial VSD are presented.

• Journal of The Korea Institute of Healthcare Architecture
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• v.7 no.2
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• pp.59-69
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• 2001

The purpose of this study is to provide a basic data for architectural planning on the wards and special quality of physical remedy spaces of geriatrics hospital. This research, to analyse dependency degree of inpatients in geriatric hospital, shows relativeness between remedy space and wards, and to show behavior of each patients reaction to there space. Result of interviewed inpatients who were sorted by age, sex, dependency degree, and days in hospital, suitable space programming is to need for physical and mental state. On the bases of survey and analysis, the basic data for planning and design the hospital for the elderly with dementia has been proposed.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.8
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• pp.2164-2172
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• 2009

The purpose of the present study was intended to assess fatigue symptoms of nurses working at special part(operating room, intensive care unit, emergency room) and ward in general hospitals, and to reveal its related factors. The self-administered questionnaires were given to 393 nurses employed in 3 participating hospitals located in Daejeon City. As a results, the special part workers had higher scores of fatigue symptoms than the ward workers. Multiple stepwise analysis revealed that the factors of influence on fatigue symptoms in the special part workers included subjective health status, age and job satisfaction, and in the ward workers, the factors of influence on fatigue symptoms included subjective health status, sleep hour, shift work and job satisfaction. In conclusion, the fatigue symptoms were higher in the special part workers than the ward workers, and its related factors were different from two worker groups.

• Journal of Korean Academy of Nursing Administration
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• v.6 no.1
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• pp.97-107
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• 2000

In human societies, there are various organizations which are unique and have different roles. Among them, hospital organization are much more complex than other organizations because of their multitude of professional groups each with its own goals. To achieve its purposes, hospital should manage each professional group effectively. Hospital nursing organizations are the core positions in hospitals for patient care. Therefore nursing organizations have have efficient nurse managers to lead nurses for their own purposes. First- line nurse managers have special tasks for patients and nurses, which include to motivating, managing communicating with the people. So they should have high self-efficacy, which is the belief that one can successfully perform the behaviors in question. Self-Efficacy of first line nurse managers that asked them for leading their staff, and their tasks, is essential to bring about self-realization of staff nurses through motivation and job satisfaction, taking advantage of sound surrounding which is able to operate her staff nurses in order to function efficiently. But there were few studies on the topic in a hospital setting. This study was designed to measure first-line nurse managers' self-efficacy. The subjects for this Study were 167 first-line nurse managers randomly selected from 18 university hospitals in Korea. The Self-Efficacy was measured using 'The general self-efficacy scale' developed by Sherer and Maddux(1982). The data were collected through questionnaires and analysed using SAS program, frequencies, percentages and Pearson' correlation coefficients. The results of this study were as follows : 1. The average of first- line nurse managers' self- efficacy was 66.7. 2. The correlation between first-line nurse managers' self- efficacy and general characteristics(age, education, career) was not significant. From the above findings, this study can suggest the following : 1. Repeat studies are needed in various hospital settings. 2. First-line nurse managers must be trained with special programs for each nursing organizations' purposes.

• The Korean Journal of Pain
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• v.26 no.4
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• pp.336-346
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• 2013

Intrathecal drug delivery is an effective and safe option for the treatment of chronic pathology refractory to conventional pain therapies. Typical intrathecal administered drugs are opioids, baclofen, local anesthetics and adjuvant medications. Although knowledge about mechanisms of action of intrathecal drugs are every day more clear many doubt remain respect the correct location of intrathecal catheter in order to achieve the best therapeutic result. We analyze the factors that can affect drug distribution within the cerebrospinal fluid. Three categories of variables were identified: drug features, cerebrospinal fluid (CSF) dynamics and patients features. First category includes physicochemical properties and pharmacological features of intrathecal administered drugs with special attention to drug lipophilicity. In the second category, the variables in CSF flow, are considered that can modify the drug distribution within the CSF with special attention to the new theories of liquoral circulation. Last category try to explain inter-individual difference in baclofen response with difference that are specific for each patients such as the anatomical area to treat, patient posture or reaction to inflammatory stimulus. We conclude that a comprehensive evaluation of the patients, including imaging techniques to study the anatomy and physiology of intrathecal environment and CSF dynamics, could become essential in the future to the purpose of optimize the clinical outcome of intrathecal therapy.