• Title/Summary/Keyword: Space availability

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Molecular Mechanism of Pancreatic Bicarbonate Secretion

  • Lee, Min-Goo;Kim, Je-Woo;Kim, Kyung-Hwan;Muallem, Shmuel
    • The Korean Journal of Physiology and Pharmacology
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    • v.6 no.3
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    • pp.131-138
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    • 2002
  • Thanks to recent progress in availability of molecular and functional techniques it became possible to search for the basic molecular and cellular processes that mediate and control $HCO_3{^-}$ and fluid secretion by the pancreatic duct. The coordinated action of various transporters on the luminal and basolateral membranes of polarized epithelial cells mediates the transepithelial $HCO_3{^-}$ transport, which involves $HCO_3{^-}$ absorption in the resting state and $HCO_3{^-}$ secretion in the stimulated state. The overall process of HCO3 secretion can be divided into two steps. First, $HCO_3{^-}$ in the blood enters the ductal epithelial cells across the basolateral membrane either by simple diffusion in the forms of $CO_2$ and $H_2O$ or by the action of an $Na^+-coupled$ transporter, a $Na^+-HCO_3$ cotranporter (NBC) identified as pNBC1. Subsequently, the cells secrete $HCO_3{^-}$ to the luminal space using at least two $HCO_3{^-}$ exit mechanisms at the luminal membrane. One of the critical transporters needed for all forms of $HCO_3{^-}$ secretion across the luminal membrane is the cystic fibrosis transmembrane conductance regulator (CFTR). In the resting state the pancreatic duct, and probably other $HCO_3{^-}$ secretory epithelia, absorb $HCO_3{^-}.$ Interestingly, CFTR also control this mechanism. In this review, we discuss recent progress in understanding epithelial $HCO_3{^-}$ transport, in particular the nature of the luminal transporters and their regulation by CFTR.

Is HAZOP a Reliable Tool? What Improvements are Possible?

  • Park, Sunhwa;Rogers, William J.;Pasman, Hans J.
    • Journal of the Korean Institute of Gas
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    • v.22 no.2
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    • pp.1-20
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    • 2018
  • Despite many measures, still from time to time catastrophic events occur, even after reviewing potential scenarios with HAZID tools. Therefore, it is evident that in order to prevent such events, answering the question: "What can go wrong?" requires more enhanced HAZID tools. Recently, new system based approaches have been proposed, such as STPA (system-theoretic process analysis) and Blended Hazid, but for the time being for several reasons their availability for general use is very limited. However, by making use of available advanced software and technology, traditional HAZID tools can still be improved in degree of completeness of identifying possible hazards and in work time efficiency. The new HAZID methodology proposed here, the Data-based semi-Automatic HAZard IDentification (DAHAZID), seeks to identify possible scenarios with a semi-automated system approach. Based on the two traditional HAZID tools, Hazard Operability (HAZOP) Study and Failure Modes, Effects, and Criticality Analysis (FMECA), the new method will minimize the limitations of each method. This will occur by means of a thorough systematic preparation before the tools are applied. Rather than depending on reading drawings to obtain connectivity information of process system equipment elements, this research is generating and presenting in prepopulated work sheets linked components together with all required information and space to note HAZID results. Next, this method can be integrated with proper guidelines regarding process safer design and hazard analysis. To examine its usefulness, the method will be applied to a case study.

An Efficient Method for Allocating Storage Yard for Container Terminal (컨테이너 터미널의 장치장 활용 방안에 관한 연구)

  • Song Yong-Seok;Nam Ki-Chan;Yoo Ju-Young;Kim Tae-Won
    • Journal of Navigation and Port Research
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    • v.30 no.3 s.109
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    • pp.203-209
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    • 2006
  • Maritime transport has been occupying the biggest part of the container transportation market. With regard to container terminal management, the planning technology and the space allocation system on the yard are very significant factors to secure the stability of ship and to ensure the reliability of schedules of ship throughout keeping barycenter of vessel by right loading and fast handling of cargoes. The purposes of this paper are to illustrate the existing yard management systems such as Grouping method and Random Grounding method, and then to evaluate and compare the efficiency of yard availability between the existing management system(Grouping method) and Random Grouping which uses the forecasted inbound cargo volume at the gate by Time Base Operation.

Accuracy Evaluation and Terrain Model Creation of Urban Space using Unmanned Aerial Vehicle System (무인항공시스템을 이용한 도시공간 지형모델 생성 및 정확도 평가)

  • Do, Myung-Sik;Lim, Eon-taek;Chae, Jung-hwan;Kim, Sung-hun
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.17 no.5
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    • pp.117-127
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    • 2018
  • The author tried to propose the orthographic and DTM (digital terrain model) creation and evaluate the accuracy for an university campus using UAV (unmanned aerial vehicle) system. Most previous studies used GPS-based data, but in this paper, the observations of triangulation level measurements was used for comparison of accuracy. Accuracy analysis results showed that the operational requirements for aerial photographic standards are satisfied in all scenaries. The author confirmed availability in aviation photo measurements and applications using UAV (Drone). In order to create a sophisticated DTM and contour, we need to eliminate interference from building, trees, and artificial objects. The results of this study are expected to be used as the basis for future studies in the creation of DTM and the accuracy assessments using Drone.

Design and Implementation of a Freespace Manager for a Logical Volume Manager (논리볼륨 관리자를 위한 자유공간관리자의 설계 및 구현)

  • 최영희;유재수;오재철
    • Proceedings of the Korea Society of Information Technology Applications Conference
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    • 2002.11a
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    • pp.520-532
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    • 2002
  • A new architecture called the Storage Area Network(SAN) was developed in response to the requirements of high availability of data scalable growth and system performance. In order to use SAN more efficiently, most SAN operating systems support storage virtualization concepts that allow users to view physical storage devices attached to SAN as a large volume virtually. A logical volume manager plays a key role in storage virtualization. In order for mapping managers to process snap-shots and reorganizations, an efficient freespace manager is required, and it affects the overall performance of logical volume. In this thesis, we design and implement a freespace manager for logical volume manager. The freespace manager efficiently allocates physical blocks for logical blocks. Also, it processes space allocation requests for suports snapshots and reorganizations.

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A Study on the Adjustment of Eaves Curve and Roof Length of Three-Bay-Kan Buddhist Temples with the Hipped and Gable Roof (정면 3칸 팔작지붕 불전의 처마 곡선과 지붕 길이 조절에 관한 연구)

  • Wi, So-Yeon;Sung, Dae-Chul;Shin, Woong-Ju
    • Journal of architectural history
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    • v.26 no.3
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    • pp.39-49
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    • 2017
  • It is difficult to build a hipped and gable roof in slender rectangular type due to restraint in variation of lateral length caused by gongpo arranged on the side, purlin space and the form of gable part and aesthetical effect of chunyeo maru. Against this backdrop and with the assumption that this phenomenon is more apparent in roofs of three-bay-kan Buddhist temples with the hipped and gable roof among national treasure Buddhist temples, this study has aimed to prove that a roof can be built in a less slender rectangular type than that of flat form and to present the building methodology and found the following findings. First, The ratio of lateral to longitudinal length of the roof has been adjusted by protruding the chunyeo and the method of adjusting the ratio of lateral to longitudinal length of the roof is considered to be determined depending on the availability of woods to be used in chunyeo. Second, in order to symmetrically arrange the edge of the roof, which is critical from the perspective of construction morphology, the chunyeo angle has been intentionally adjusted to reduce the gap of length between the front roof and the lateral roof. To sum up, the characteristic of the hipped and gable roof, which is difficult to be built in slender rectangular type, is more clearly shown in the roof and it is identified that the length of the front roof and the lateral roof has been intentionally adjusted to achieve the symmetrical arrangement of roofline of the roof edge.

Basic Research for Sustainable Development of the Compact City -Focusing on the Characteristics Analysis for City/ Society/Residence of Europe/USA/Japan- (지속가능한 콤팩트도시 개발을 위한 기초 연구 -유럽, 미국, 일본의 도시, 사회, 거주 특징분석을 중심으로-)

  • Baek, Seung-Kwan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.8
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    • pp.595-604
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    • 2016
  • This study discusses the sustainable development of the compact city. The problems of urban sprawl have long been recognized. Urban sprawl results from the confluence of several factors: the lure of cheap open land outside the city, advances in transportation, the ready availability of capital to buy property, the increase in the number of real estate developers and the mass production of housing. The term compact city has the opposite connotation to urban sprawl. Compact cities provide a more energy efficient and less polluting environment, because dwellers within them live closer to shops and work and can easily walk, bike or take public transport. In other words, the compact city has the objective of facilitating the integration of the different functions through the intensive development of various facilities, such as residences, commerce, businesses and of improving the efficiency of urban energy usage by decreasing the volume of traffic.

Optimal Fault-Tolerant Resource Placement in Parallel and Distributed Systems (병렬 및 분산 시스템에서의 최적 고장 허용 자원 배치)

  • Kim, Jong-Hoon;Lee, Cheol-Hoon
    • Journal of KIISE:Computer Systems and Theory
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    • v.27 no.6
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    • pp.608-618
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    • 2000
  • We consider the problem of placing resources in a distributed computing system so that certain performance requirements may be met while minimizing the number of required resource copies, irrespective of node or link failures. To meet the requirements for high performance and high availability, minimum number of resource copies should be placed in such a way that each node has at least two copies on the node or its neighbor nodes. This is called the fault-tolerant resource placement problem in this paper. The structure of a parallel or a distributed computing system is represented by a graph. The fault-tolerant placement problem is first transformed into the problem of finding the smallest fault-tolerant dominating set in a graph. The dominating set problem is known to be NP-complete. In this paper, searching for the smallest fault-tolerant dominating set is formulated as a state-space search problem, which is then solved optimally with the well-known A* algorithm. To speed up the search, we derive heuristic information by analyzing the properties of fault-tolerant dominating sets. Some experimental results on various regular and random graphs show that the search time can be reduced dramatically using the heuristic information.

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A Study on Applicability of Custom-Tailored Clothing of 3D Virtual Clothing System - Focused on Middle-Aged Women - (3 시스템의 맞춤복 시장 적용가능성에 관한 연구 - 중년여성을 대상으로 -)

  • Lee, Su-Yeon;Lee, Jung-Soon
    • Journal of Fashion Business
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    • v.14 no.4
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    • pp.161-173
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    • 2010
  • This study aims to examine for efficient production methods of custom-tailored clothing and application of 3D virtual clothing system in custom-tailored clothing market, by producing and analyzing both real clothing and 3D virtual clothing. For this study, a middle-aged woman is selected as the subject figure and one-piece is selected as the experimental clothes item. In real clothing, I conducted the wearing evaluation for experts and the subject figure. And In the virtual clothing, I conducted the wearing evaluation with i-Designer using 3D virtual clothing on simulation program. There are some differences between the data from body scanning and the real body size. In the custom-tailored clothing market in which the fitness is important, the research which measures the more exact data is needed. And in the case of complicate design, the functions which measure the activity and the fitness variously and correct the parts of curves are needed. This study experiments the availability of application of 3D Virtual Clothing System in custom-tailored clothing market by selecting one-piece as the experimental clothes item. So the follow-up studies for the other designs and fabrics are needed. Also, if the studies for checking the clothes pressure, the amount of composure, the space between skin and clothing when the virtual model wearing clothes is walking or shaking his arms are proceeding, then 3D virtual clothing System is applicable in custom-tailored clothing market. But there are some restrictions and lack of education in virtual clothing System yet, and it makes hard for workers in clothing market to use it in real production. However, 3D virtual clothing System will be practical in real market if there would be more research on its usability and practicality, and workers in clothing market can be easily educated on techniques of 3D virtual clothing system.

A Mapping Method for a Logical Volume Manager in SAN Environment (SAN 논리볼륨 관리자를 위한 매핑 기법)

  • 남상수;송석일;유재수;김창수;김명준
    • Journal of KIISE:Computing Practices and Letters
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    • v.9 no.6
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    • pp.718-731
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    • 2003
  • SAN(Storage Area Network) was developed in response to the requirements of high availability of data, scalable growth, and system performance. In order to use the SAN more efficiently, most of the SAN operating software supports storage virtualization concepts that allow users to view physical storage devices of the SAN as a large volume. A logical volume manager plays a key role in storage virtualization. It realizes the storage virtualization by mapping logical addresses to physical addresses. In this paper, we design and implement an efficient and flexible mapping method for the logical volume manager. Additionally we also design and implement a free space management method for flexible mapping. Our mapping method supports a snapshot that preserves a volume image at certain time and on-line reorganization to allow users to add or remove storage devices to and from the SAN even while the system is running. To justify our mapping method, we compare it with the mapping method of the GFS (Global File System) through various experiments.