• 사상체질의학회지
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• 제15권1호
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• pp.27-38
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• 2003

Purpose: This study has focused on evaluating the effectiveness and accuracy of the questionnaire which considered as a basic data to indentify constitution Methods: By analysing the tendency of the respondents who has defined constitution by clinical diagnosis and comparing of their answers, the result of their constitution analysis by our questionnaire were re-examed. The answer of each question to each constitution were tested how it is relevent to a scale of a constitution. So I analysed each item response rates on QSCCII of those who had been tested and diagnosed as Taeyangin, Soyangin, Taeumin, Soeumin respectively. Results: 1. From the 537 results of QSCCII of those who were examined by professors, I made a selected Taeyang scale which is consists of 18 items, a selected Soyang scale which is consists of 40 items, a selected Taeum scale which is consists of 41 items and a selected Soeum scale which is consists of 32 items. 2. I have found that there is limitation to find out constitution by the questionnaire we used, one I hope that suitable questionnaire will be developed for the research in the future

• 사상체질의학회지
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• 제29권2호
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• pp.136-153
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• 2017

Objectives This experimental study was designed to investigate the effect of Phaseolus angularis shell on metabolic syndrome. Methods Each 5 C57BL/6J mice were randomly assigned to normal diet group, high-fat diet(HFD) control group, high-fat diet plus 15.6 mg/kg/day of Orlistat(HFD-Orlistat) group, high-fat diet plus 100mg/kg/day of Phaseolus angularis shell extract(HFD-PAS_E) group. Weight, the blood chemical and hematologic parameter was med. The mRNA expression was assayed through Reverse transcriptase polymerase chain reaction(RT-PCR). Results In HFD-PAS_E group, the body weight gain, weight of liver, and the level of LDL-Cholesterol were significantly decreased and the level of HDL-Cholesterol were significantly increased. The size of adipocyte in HFD-PAS_E group was smaller than HFD group's. In HFD-PAS_E group, the expression of leptin, PPAR-${\gamma}$, AP2/FABP4 mRNA in liver adipocyte tissue was decreased, the expression of Adiponectin, UCP-2 mRNA in liver adipocyte tissue was increased and the expression of Leptin, C/EBP-a, AP2/FABP4 mRNA in epididymal adipocyte tissue was decreased. Conclusion These results suggest that Phaseolus angularis shell has inhibitory effects on metabolic syndrome by reducing the body weight and the levels of lipid contents in high-fat-diet induced obese mice.

• 미생물학회지
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• 제46권2호
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• pp.162-168
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• 2010

국내에서 분리된 독소생산 Microcystis 속과 조류 대발생 시기에 대청호, 충주호, 용담호, 소양호, 및 의암호에서 채취한 시료에서 조류 독소인 microcystins의 생합성에 관여하는 mcyA 유전자의 염기서열 다양성을 분석하였다. GenBank에 등록된 mcyA 염기서열과 비교한 결과, 국내 호소에서 분리된 Microcystis 속의 mcyA 유전자 염기서열은 매우 낮은 다양성을 나타내었다. 환경 시료 분석 결과, 2-3종류의 clone이 전체의 87-100%를 차지하였으며, Anabaena 속이나 Planktothrix 속의 mcyA 유전자와 유사한 염기서열은 발견되지 않았다. 이러한 결과로 볼 때, 대상 호소에서 microcystins는 주로 Microcystis 속에 의해 생산되며, 독소 생산에 관여하는 mcyA 유전자의 염기서열은 보존되어 있는 것으로 판단된다.

• 대한한의학회지
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• 제30권1호
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• pp.26-39
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• 2009

Objectives: Pulse energy values recorded with an add-pres sure-type pulse apparatus were correlated with Sasang constitutional syndromes in order to match pulse energy values with Sasang prescriptions. Methods: The pulse energy values were measured with Daeyo Pulse Apparatus at the Gwan pulse point of both wrists. Prescriptions were divided into two major categories of interior syndromes or exterior syndromes, and categorized according to major component herbs specific to each of the four Sasang constitutions, and the relationship between the pulse energy and each groups divided by their prescription was studied. Results: About 10% of all people had nonmal pulse energy values. 10% had values over normal range, and $70\sim80%$ had lower values than normal. The normal range of pulse energy was regarded as being between 450 and 700. Conclusions: 1. For patients of the Soeum constitution, prescriptions without Panax ginseng is suitable for patients with high pulse energy, and prescriptions containing Panax ginseng are suitable for patients who have lower pulse energy. 2. All prescriptions for the Soyang constitution containing Rehmannia radix preparata or Comus officinalis are suitable for patients who have lower pulse energy, and prescriptions containing Rehmannia radix or Gypsum fibrosum are applicable to patients with pulse energy values higher than normal. 3. Most prescriptions for the Taeum constitution containing Semen coicis or Semen castaneae are suitable for patients with lower pulse energy, and prescriptions containing Radix puerariae or Radix et rhizoma rhei can be prescribed for patients who have lower pulse energy levels. 4. The Taeyang constitutional prescription Ogapijangcuck-tang is suitable for patients who have higher pulse energy levels and Mihudeungsikjang-tang is better for patients with lower than normal pulse values. As described above, the pulse energy level of each patient can be matched with a specific Sasang constitutional prescription. If this relationship is taken into consideration with other conventional symptoms, it can be helpful in diagnosis, improving efficacy of treatment, and be used as objective evidence.

• Journal of Acupuncture Research
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• 제18권5호
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• pp.204-212
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• 2001

Objective : Septic arthritis is a disease of when bacterial infection causes inflammatory reactions to occur in the body's joints. Following damage, stiffness, and disformity may occur in the joints. Initially antibiotic treatment is used. Later treatment is the preservation and rehabilitation of the joints. Here we report a case of sequelae of septic arthritis, which is treated and managed by ways of oriental medicine. Methods : We considered that symptoms like fever, arthralgia and ankylosis were similar to Yeol-bi(熱痺) and the patient's constitution was Soyang-in(少陽人). So Yangguksanhwa-tang(凉膈散化湯) was used as medication, and acupuncture, TENS, rehabilitation treatment was carried out. Also Kinesio & Cross(Geok-ja(격자)) taping therapy was done after the contact test. Results : After 4-7 days from the end of antibiotic treatment, the patient regained movement in the joints. After 3 weeks, the patient was able to support his own weight, and one week later joints were restored to nearly normal range. Therefore sequelae of Septic arthritis is thought to be treated earlier when the above treatment is used, compared to western treatment, which mainly consist of antibiotic treatment. Conclusion : This case was managed by herbal medicine, acupuncture, TENS, rehabilitation treatment, and Kinesio & Cross(Geok-ja) taping therapy on sequelae of Septic arthritis. Earlier improvement was gained comparatively to western treatment, which mainly consist of antibiotic treatment.

• 한국한의학연구원논문집
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• 제7권1호
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• pp.105-114
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• 2001

This study was carried out to investigate correlation with food preference of subjects in three constitution groups on the view point of constitutional medicine. The constitutions of 124 college students(male 80, female 44) was classified by QSCC II method. Food preference of the subjects was surveyed in accordance with suggested foods for each constitution and was analyzed using Hedonic scale. The distribution of the constitutional revealed that Soeum individuals accounts 53%, followed by ; Soyang 19%, Taeum 28%. For men, sorghum, potatoes, beef, scombroid, oyster, saury, octopus, codfish, walleye pollack, shrimp, croaker, pineapple, eggplant, leek, pumpkin, toenjang, draft beer, diluted liquor, coffee, cocoa were statistically different in food preference score by sasang constitution(p<0.05). For woman, chicken, pollack roe, a walleye pollack, persimmon, jujube, melon, citron, celery, burdock, vinegar, bean-paste soup, draft beer, ginseng, honey were statistically different in food preference score by sasang constitution(p<0.05). Association of sasang constitutions and food thought to be harmful or healthy to each constitution was analyzed. But Food preference score of food thought to be harmful or healthy were not statistically different in score among sasang constitutions. This results suggested that food intake patterns of subjects were associated with sasang constitutional food in parts.

• 대한토목학회논문집
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• 제37권1호
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• pp.231-238
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• 2017

용수공급시설의 설계 및 운영에 기준이 되는 이수안전도는 용수공급안전도의 평가를 위한 중요한 지표이지만, 이수안전도에 대한 일관된 지침이 없어 댐 설계 과정에서 저마다 사용된 자료기간과 평가 방법이 서로 상이한 문제점이 있다. 따라서 본 연구에서는 다목적댐의 용수공급능력을 일관성 있게 평가하기 위해 가뭄의 심도와 지속기간을 동시에 고려할 수 있는 이변량 가뭄빈도해석을 수행하였다. 확률론적 개념을 바탕으로 가뭄사상을 평가하여 댐유역의 가뭄특성을 분석하였으며, 우리나라의 5개 다목적댐(소양강, 충주, 안동, 대청, 섬진강)을 대상으로 특정 가뭄상황에서의 용수공급능력을 평가하였다. 그 결과 여름과 가을에는 자체 유입량만으로 안정적인 용수공급이 가능하지만, 강수량이 적은 봄과 겨울에는 1년 빈도의 작은 가뭄에도 용수부족이 발생하는 것으로 나타났다.

• 사상체질의학회지
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• 제8권2호
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• pp.151-163
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• 1996

VNTR 및 STR 분석은 유전자지문법 (DNA fingerprinting)에서 사용되는 방법으로 개체의 식별 등을 목적으로 하는 범죄수사 및 기타 유전적 분석 연구에서 많이 쓰이고 있는 유전적 분석 방법이다. 본 연구는 사상체질의 판별에 의해서 분류된 각 체질들이 유전적으로 차이가 있는지를 조사하기 위하여 각 체질인의 제놈 DNA를 대상으로 VNTR 및 STR의 분석을 실시하여서 사상체질의학의 객관화 및 그 임상활동에 관한 유용한 자료를 제공함을 목적으로 추진되었다. 본 연구에서 실시한 MCT118, YNZ22 locus를 이용한 VNTR 분석에서는 체질별로 나타난 allele의 분포 양상이 다양할 뿐만 아니라 각 체질에서 나타난 allele의 분포빈도가 체질별로 유의적인 차이를 보이지 않았다. 따라서 VNTR의 분석을 이용하여서는 사상체질의 네 가지 체질 그룹에 대한 유전적 동질성 및 그룹간 유전적 상이성을 유추해 내기가 어려운 것으로 사료되었다. 한편 allel 의 종류가 적고 따라서 그 분포 양상이 VNTR에 비해서 다양하지 않은 STR 중에서 본 연구에서는 TH01과 vWA locus에 대한 분석을 실시하였는데 그 결과 vWA locus에서는 각 allele No.의 분포 양상이 체질별로 다소 다르게 나타났다.

• 사상체질의학회지
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• 제28권2호
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• pp.123-131
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• 2016

Objectives We observed what effects of Paced Breathing(PB) in specific respiration rate have on heart rate variability (HRV) according to Sasang Constitution.Methods HRV of 72 healthy participants in sitting position was recorded while they carried out usual breathing, 0.2Hz, 0.1Hz, and 0.05Hz PB each 5 minutes in consecutive order. Five minute of relaxation was permitted between each breathing. Finally, HRV indices were statictically analyzed of 32 participants (SOEUM: 11, SOYANG: 10, TAEEUM: 11) after data out of accord with respiration rate or outliers were excluded.Results and Conclusions According to respiration rates, there was no statistical significance of HRV among Sasang Constitution. Regardless of Sasang Constituion, 0.2Hz PB increased mean heart rate and decreased natural logarithmic low frequency(lnLF) oscillation of HRV without the change of natural logarithmic high frequency(lnHF), while 0.1Hz PB increased lnLF and standard deviation of N-N interval(SDNN), and slightly decreased lnHF without the change of mean heart rate. 0.05 Hz PB also showed the same effect as 0.1Hz PB, but was impracticable.

• 혜화의학회지
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• 제18권1호
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• pp.9-18
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• 2009

Objectives and Methods: The treatments of osteoporosis in occidental medicine are need complementations for reason of low-continuation and adverse-drug-reaction. So we would have literature centered consideration both oriental medical cognition and acupuncture-moxibustion therapy in osteoporosis. Results: 1. Deficiency of bone marrow caused by heat in the kidney and deficiency of kidney Gi, is causative of osteoporosis in pathology in oriental medicine. 2. Bone flaccidity and bone impediment are similar with osteoporosis. Withered bone comes under pathogenesis of bone flaccidity. And heavy debilitating disease of the bone is exacerbation of bone impediment. 3. In acupuncture-moxibustion therapy of osteoporosis, Bladder Meridian of Foot Taeyang, Kidney Meridian of Foot Soeum, Gallbladder Meridian of Foot Soyang, Lung Meridian of Hand Taeeum, Large Intestine Meridian of Hand Yangmyeong, Spleen Meridian of Foot Taeeum, Conception Channel, Stomach Meridian of Foot Yangmyeong, and Heart Meridian of Hand Soeum are used much in the order named. 4. In acupuncture-moxibustion therapy of osteoporosis, Hyeonjong(GB39, 7times), Daejeo(BL11, 3times), Sanggwan(GB3, 2times), Sinsu(BL23, 2times), Gyeoksu(BL17, 2times), Honmun(BL47, 2times), Buryu(KI7, 2times), Taebaek(SP3, 2times), Sanggu(SP5, 2times), Sangnyeom(LI9, 2times) are used much in the order named. Conclusions: In treatment of osteoporosis, we could make full use of acupuncture-moxibustion therapy. And we need active and persistent study about osteoporosis.