• Title/Summary/Keyword: Sources of variation

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Estimation of Genetic Parameters of Body Weight Traits in Ghezel Sheep

  • Baneh, Hasan;Hafezian, Seyed Hasan;Rashidi, Amir;Gholizadeh, Mohsen;Rahimi, Ghodrat
    • Asian-Australasian Journal of Animal Sciences
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    • v.23 no.2
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    • pp.149-153
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    • 2010
  • The present study was carried out to estimate genetic parameters for body weight traits in Ghezel sheep. The data set used was records of 9,221 lambs from 180 sires and 5,060 dams for birth weight (BW), 7,206 lambs from 167 sires and 4,497 dams for weaning weight (WW) and 6,112 lambs from 157 sires and 3,841 dams for 6-months weight (6 MW), which were collected from 1999 to 2007 (9-years) at Ghezel sheep Breeding Station in west Azarbaijan. Variance components and corresponding genetic parameters were obtained with univariate analyses fitting animal models using restricted maximum likelihood (REML) methods. The most suitable model for each trait was determined based on log likelihood ratio tests. Birth year, lamb gender, type of birth, age of dam and herd were significant sources of variation on BW, WW and 6 MW (p<0.01). Direct estimate of heritability for BW, WW and 6 MW was 0.24, 0.29 and 0.37, respectively. The estimate of maternal permanent environmental variance as a proportion of phenotypic variance was 0.09 and 0.05 for BW and WW, respectively. The results of this study showed that genetic progress for growth traits is possible by selection.

Distribution of Airborne Hexavalent Chromium Concentrations in Large Industrial Complexes in Korea

  • Kang, Byung-Wook;Lee, Hak-Sung;Kim, Jong-Ho;Hong, Ji-Hyung;Kim, Rok-Ho;Seo, Young-Kyo;Han, Jin-Seok;Baek, Kyung-Min;Kim, Min-Ji;Baek, Sung-Ok
    • Asian Journal of Atmospheric Environment
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    • v.10 no.4
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    • pp.208-216
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    • 2016
  • This paper reports the results of a field evaluation which used sampling and analytical methods to determine the levels of airborne hexavalent chromium Cr(VI) in major industrial complexes in Korea over a seven year period (2007-2013). Cr(VI) concentrations were determined using cellulose filter sampling and ion chromatography analysis. In order to validate the analytical performance of these methods, studies were also carried out to investigate data quality control (QC) parameters, such as the method detection limit (MDL), repeatability, and recovery efficiencies. The average concentrations of Cr(VI) for the nine industrial complexes in Korea were in the range of 0.09 to $1.40ng/m^3$, which is similar to of the concentrations in other industrial areas around the world. The impacts of Cr(VI) emissions from industrial areas on Cr(VI) concentrations in neighboring-residential areas were considerably low, and the dispersion of Cr(VI) from industrial areas to residential areas was estimated to be 'not-significant'. Cr(VI) levels were not affected by seasonal variation, which suggests that chromium was emitted continuously from the industrial sources throughout the year. The concentration of Cr(VI) measured accounted for 0.7 to 9.4 percent of the total chromium level, which is a low percentage compared to those in other urban areas around the world. This is the first report in an international journal of a field study conducted in Korea to determine the concentration of Cr(VI) in the ambient air of industrial and residential areas.

Reliability and Validity on Measurement Instrument for Health Status Assessment in Occupational Workers (직장인들의 건강수준 평가를 위한 측정도구의 신뢰도와 타당도 분석)

  • Koh, Sang-Baek;Chang, Sei-Jin;Kang, Myung-Guen;Cha, Bong-Suk;Park, Jong-Ku
    • Journal of Preventive Medicine and Public Health
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    • v.30 no.2 s.57
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    • pp.251-266
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    • 1997
  • In order to test scaling assumption, and to assess the validity, reliability, and acceptability of the Short form 36(SF-36) health survey questionnaire, we conducted a survey. Samples were 296 workers who had been employed in small sized companies. All scale passed for item internal consistency(100% sucess rate) and item discriminant validity(100% success .ate). Reliability coefficients were ranged from the lowest 0.51 to the highest of 0.85. For 87.5% of the total workers, inconsistent responses were not observed. Only 3.0% of the total workers failed two or more checks. Factor analysis was performed using principal axis factor method and quartimax rotation. In this survey, the SF-36 retained available psychometric properties even when used in a generally healthy worker group. But further study with some consideration to develope health status measurement is expected : first, the definition of health status should be rationalized. Second, the measurement of outcome is an important consideration in evaluations of quality of care. But ambiguities hinder understanding of this important topic. Third, internal consistency should be interpreted with caution as an indication reliability because it ignores potentially important sources of variation that can occur over time.

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Selection of Tropane Alkaloids High-Producing Lines by Single Cell Cloning of Hyoscyamus niger L. Root Cultures

  • Min, Ji-Yun;Park, Dong-Jin;Jeong, Mi-Jin;Song, Hyun-Jin;Kang, Seung-Mi;Kang, Young-Min;Choi, Myung-Suk
    • Journal of Korean Society of Forest Science
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    • v.98 no.2
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    • pp.142-147
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    • 2009
  • Hyoscyamus species is sources of the hypnotic and sedative drugs hyoscyamine and scopolamine. Single cells of Hyoscyamus niger were dissociated from suspension cultures and adventitious roots obtained from single-cell clones which were cultured on B5 medium containing 3% (w/v) sucrose, 0.1 mg/L IBA and 0.4% (w/v) gelrite. H. niger adventitious root lines showed wide variation in tropane alkaloids production and growth. An effective selection of 200 root lines was made possible by the application of the 'Dragendorff's reagent' for qualitative detection of the alkaloids from root. A high correlation coefficient (r=0.9390) was observed between the values obtained with the two methods based on HPLC and Dragendorff's reagent analysis. Among the selected roots, the highest scopolamine content was 16.64 mg/g DW (Hn-59), which was 8.82-fold more productive than the lowest alkaloid producing line (Hn-25). Here, we established an efficient selection method on tropane alkaloids production and suggest that the Dragendorff's reagent is of great practical value in selection of invisible compounds.

A Basic Study on the Stress Field in the Electrode Interface of the Planar SOFC Single Cell (평판형 SOFC 단전지 전극계면에서 발생되는 응력장에 관한 기초적 연구)

  • Park, Chul Jun;Kwon, Oh Heon;Kang, Ji Woong
    • Journal of the Korean Society of Safety
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    • v.28 no.5
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    • pp.5-9
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    • 2013
  • Recently, eco-friendly sources of energy by fuel cells that use hydrogen as an energy source has emerged as the next generation of energy to solve the problem of environmental issues and exhaustion of energy. A solid oxide fuel cell(SOFC) classified based on the type of ion transfer mediator electrolyte has actively being researched. However, the reliability according to the thermal cycle is low during the operation of the fuel cell, and deformation problem comes from the difference in thermal expansion coefficient between the electrode material, the components made of ceramic material is also brittle, which means disadvantages in terms of the strength. Therefore, in this study, considering the states of the manufacturing and operating of SOFC single cells, the stress analyses in the each of the interfacial layer between the anode, electrolyte and the cathode were performed to get the basic data for reliability assessment of SOFC. The obtained results show that von Mises stress according to the thickness direction on operating state occurred maximum stress value in the electrolyte layer. And also the stresses inside the active area on a distance of 1 ${\mu}m$ from the electrode interface were estimated. Futhermore the evaluation was done for the variation of the stress according to the stage of the operation divided into three stages of manufacturing, stack, and operating.

Biological Constituents of Aged Garlic Extract as Biomarker (숙성마늘 extract 의 biomarker로서 생리활성 성분)

  • Yang, Seung-Taek
    • Journal of Life Science
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    • v.19 no.1
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    • pp.138-146
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    • 2009
  • Garlic (Allium sativum) are an agronomically important genus because of their sulfur flavour components. The majority of the volatiles flavour principles are generated through the enzymatic hydrolysis of the non-volatile organosulfur compounds. However, these compounds may be possible sources of new novel bioacuve and therapeutic principles. Garlic has strong antioxidant activity, and epidemiological studies support the fad that diets rich of garlic may prevent some of the chronic diseases. The health cares of garlic likely arise from a wide variety of components, which may work synergistically. The chemical changes of garlic composition makes it plausible that a variation in processing can lead to acquisition of differential chemical compositions of garlic products. Especially highly unstable allicin can easily disappear during processing and are quickly transformed into a various organosulfur compounds. Various supplements of garlic, particularly aged garlic extract (AGE), are known to possess a promising antioxidant potential and are effective in prevention of chronic diseases because of the bioactive constituents. Although all of active ingredients of AGE are not elucidated, water-soluble components of AGE, including S-allylcysteine, S-allylmercaptane, steroid saponins, tetrahydro-${\beta}$-carboline derivatives, and fructosyl-arginine, appears to be associated with the pharmacological effects of AGE. Consequently, the allicin free garlic components such as S-allylcysteine, S-allylmercaptane, steroid saponins, tetrahydro-${\beta}$-carboline derivatives, and fructosyl-arginine can be applicable to standardization of the quality of commercial garlic products. This review provides an insight into garlic's biomarkers and presents evidence that they may either prevent or delay chronic disease associated with aging.

Estimation of Genetic Variance Components of Body Size Measurements in Hanwoo (Korean Cattle) Using a Multivariate Linear Model

  • Lee, Jung-Jae;Kim, Nae-Soo
    • Journal of Animal Science and Technology
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    • v.52 no.3
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    • pp.167-174
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    • 2010
  • The objectives of this study were to quantify the combination values of the principal components and factors calculated using body measurements of Hanwoo (Korean Cattle) and estimate their heritabilities. The technique of multivariate analysis was used to reduce a large number of variables to a smaller number of new variables and characterize cattle according to body shape. The analyses were performed using 1,979 cattle at 12 months of age and 936 cattle at 24 months of age. The data for the analyses was obtained from progeny tests performed on Korean Cattle for 6 years from 2003 to 2008. The phenotypic correlations among these traits were estimated to range from 0.32 to 0.90 at 12 months of age and from 0.21 to 0.82 at 24 months of age. The first principal components (PC1s) indicated a weighed average of overall body measurements, accounting for 99.91% of the total variation for both periods of test. The two first PCs had positive coefficients for all body measurements. The major sources of PC, such as chest girth (CG), body length (BL), rump height (RH), and wither height (WH) were similar for both test periods. The heritabilities for PC1, the first factor score (FS1), and the second factor score (FS2) were estimated by multivariate REML method. The estimated heritabilities for PC1, FS1, and FS2 were 0.33, 0.38, and 0.40, respectively, at 12 months of age and 0.26, 0.76, and 0.58 at 24 months of age. Further studies are needed to determine whether the heritabilities of FS1 and FS2 at 24 months of age were overestimated.

Trends of Breast Cancer Incidence in Iran During 2004-2008: A Bayesian Space-time Model

  • Jafari-Koshki, Tohid;Schmid, Volker Johann;Mahaki, Behzad
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.4
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    • pp.1557-1561
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    • 2014
  • Background: Breast cancer is the most frequently diagnosed cancer in women and estimating its relative risks and trends of incidence at the area-level is helpful for health policy makers. However, traditional methods of estimation which do not take spatial heterogeneity into account suffer from drawbacks and their results may be misleading, as the estimated maps of incidence vary dramatically in neighboring areas. Spatial methods have been proposed to overcome drawbacks of traditional methods by including spatial sources of variation in the model to produce smoother maps. Materials and Methods: In this study we analyzed the breast cancer data in Iran during 2004-2008. We used a method proposed to cover spatial and temporal effects simultaneously and their interactions to study trends of breast cancer incidence in Iran. Results: The results agree with previous studies but provide new information about two main issues regarding the trend of breast cancer in provinces of Iran. First, this model discovered provinces with high relative risks of breast cancer during the 5 years of the study. Second, new information was provided with respect to overall trend trends o. East-Azerbaijan, Golestan, North-Khorasan, and Khorasan-Razavi had the highest increases in rates of breast cancer incidence whilst Tehran, Isfahan, and Yazd had the highest incidence rates during 2004-2008. Conclusions: Using spatial methods can provide more accurate and detailed information about the incidence or prevalence of a disease. These models can specify provinces with different health priorities in terms of needs for therapy and drugs or demands for efficient education, screening, and preventive policy into action.

A Basic Study on the Analysis Method of Thermography (Thermography의 분석방법에 관한 기초연구)

  • Lee, Hyuk-Jae;Park, Young-Jae;Oh, Hwan-Sup;Lee, Sang-Chul;Park, Young-Bae
    • The Journal of the Society of Korean Medicine Diagnostics
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    • v.9 no.2
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    • pp.110-122
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    • 2005
  • Background: The basic concept of thermographic interpretation is the thermologic equality of both side in normal person. But both sides diseases were limited diagnostic values by thermographic interpretation, and this interpretation does not apply to the case in thermal temperature of each part of body. Nevertheless, the measurement conditions are not standardized. So, for its clinical applications are extended, we think that the measurement conditions are considered the individual variations. Objectives: The purpose of this study is to examine the optimum conditions thermal temperature of the time period and region are not effected by internal and external variables. Methods: After the subjects took off their clothes, the filming were repeatedly five times made on duration of 5minutes during 20minutes. We selected nine regions around acupoints including Yin dang[印堂, HN1], Sugu[水溝, GV26], Ch’ondol[天突, CV22], Chonjung[CV17], Chung-wan[中脘, CV12], Ch’onch'u[天樞 S25], No-gung[勞宮, P8], and calculated based on the utility of R.O.I.(Region of Integer) in our system these points temperature. We measured the optimal time period and region that has little variation of thermal temperature. Results: The results shows that the optimal time period is 20minutes after undressed, and the optimal region is the region around acupoints including Sugu[水溝, GV26]. Conclusions: we obtained the measurement conditions were considered the individual variations. And also, this study offers basic sources for that the measurement conditions would be standardized. Furthermore, based on this results, we expect that clinical applications using thermography would be extended.

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A Basic Study on Fall Patterns for Fracture Prevention System (골절방지 시스템을 위한 낙상 패턴에 관한 기초 연구)

  • Kim S.H.;Kim K.;Jung S.H.;Kim G.B.;Kwon T.K.;Hong C.U.;Kim N.G.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2005.06a
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    • pp.1925-1928
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    • 2005
  • In recent years, the importance of the characterization of fall for a fracture prevention system keeps increasing since fracture from a fall can lead to serious health problems. Fall is one of the major sources which increase morbidity in elderly people. In terms of the cost and the influence to the quality of life, the most serious injury with hip fractures is caused by falls. The traditional methods in characterizing fall patterns have been mainly by the epidemiological surveys. With surveys, the exact data of fall patterns can not been acquired. In this paper, we measured and analyzed with the parameters related to fall pattern such as velocities and accelerations during the motion of falls using 3D motion capture program. We acquired the parameters of the fall pattern of intentional and unexpected fall. The result showed that the variation of velocity and acceleration during fall was very important in characterizing fall pattern, which of vital importance for the development of a fracture prevention system and for the safety of the elderly

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