• Journal of Preventive Medicine and Public Health
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• 제26권2호
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• pp.192-201
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• 1993

Epidemiologic investigation was conducted on January, 1993 in Seoul to identify the cause of an infant methemoglobinemia. Field investigation of the area of outbreak, survey of household and family members, analysis of ground water, and blood tests of involved family members were performed. Following results were obtained On analyzing the quality of the ground water on patient's household high levels of nitrate was found indicating contamination of water as the cause of a methemoglobinemia outbreak. On analysing the quality of the ground waters on seven other places within the neighborhood five were contaminated by nitrate in concentration that exceeded the permissible limit implying presence nearby source of contamination. Sources of contamination were thought to be originating from human waste in conventional bathroom facilities, chicken manure used in nearby orchards and plant fields or fertilizers. But the results of water analysis with presence of bacteria or E.coli, concentration of potassium, phosphate and the past history of diarrhea among family members, chicken manure suggested the most possible source of contamination. To evaluate the health status of members in the neighborhood past history was reviewed revealing no prior existence of patient with cyanosis and 65 people in the neighborhood had normal levels of methemoglobin concentration in their blood. Conclusively, the ground water on patient's household was contaminated with nitrate and despite provision of adequate water supply, family members of the patient along with their distrust in the water supply system had used ground water as their source of drinking water resulting of methemoglobinemia. Many suburban area of Seoul and country side thought to be having similar problems concerning contaminated ground water supply and dormant outbreak of patients as a result of the drinking of the contaminated water. Epidemiologic investigation and water analysis of ground waters are advised.

• 한국산업정보학회논문지
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• 제23권3호
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• pp.25-34
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• 2018

본 논문은 세탁물 건조기의 고효율과 건조성능 향상을 위한 탄소나노섬유의 열원(히팅모듈)을 설명하였고, 이 열원의 적용 가능성을 평가하는데 집중하였다. 제안된 히팅모듈의 설계를 위해, 탄소나노섬유램프의 표면온도와 표면온도분포특성에 관한 실험이 수행되었다. 그 램프의 표면온도는 램프에 흐르는 전류의 증가와 함께 선형적으로 증가하였고, 그 램프의 길이가 짧을수록 증가하는 패턴을 보였다. 제안된 히팅모듈은 건조효율, 세탁물의 수분증발률, 건조동작 중 드럼의 내부온도를 기반으로 평가되었다. 건조효율은 KS C 9319의 기준인 45%를 충족하였고, 수분증발률과 드럼의 내부온도는 각각 98.88%와 평균 $61.1^{\circ}C$로 S사의 제품과 대등한 건조성능을 보였다. 그 평가와 실제 건조실험 결과로부터, 제안된 탄소나노섬유램프 히팅모듈은 건조효율과 건조성능의 측면에서 세탁물 건조기의 열원으로 적용 가능할 것으로 판단되며, 높은 온도의 열원, 우수한 발열량, 원적외선 방출에 의한 건조성능의 향상과 세탁물의 살균효과를 얻을 수 있다. 추가적으로, 그 건조기들 사이에 건조효율 성능차이가 열원의 소비전력을 기반으로 상세히 분석되었다.

• 천문학회보
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• 제43권1호
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• pp.35.4-36
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• 2018

$Ly{\alpha}$ blobs are mysterious, giant (~100 kpc), glowing gas clouds in the distant universe. They occupy the dark matter halos that will evolve into the richest groups and clusters today. The blob's gas may be the proto-intracluster medium and their embedded galaxies are considered as the progenitors of massive cluster galaxies. Yet we do not know why $Ly{\alpha}$ blobs glow. There are evidences of kinematic measurements to exclude shocks and winds from AGN or starbursts as a power source, suggesting that photoionizing radiation or scattering of $Ly{\alpha}$ photons might be responsible. Polarization mapping can discriminate between these photo-ionization and scattering. Previous results of imaging polarimetry for $Ly{\alpha}$ nebulae are roughly consistent with scattering models. However the polarization morphologies in those of previous results are all different, motivating our polarimetric survey of $Ly{\alpha}$ nebulae for the statisticallymeaningful sample. As initial results of our survey, we present the total polarization map of the LABd05 which has the spatial offset between the peak of $Ly{\alpha}$ surface brightness and an obscured AGN. We detect the significant polarization in this target with the radially increasing polarization gradient, suggesting that scattering plays major role within this nebula. The polarization pattern is more aligned with the $Ly{\alpha}$ peak rather than the AGN (the potential energy source), indicating that the $Ly{\alpha}$ photons are originated from the region near the peak of $Ly{\alpha}$ intensity.

• 한국소음진동공학회논문집
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• 제23권9호
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• pp.841-849
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• 2013

Workers engaged in construction works have been exposed to high levels of noise during their work in tunnels. Noise is one of the major health hazards for employees working in construction sites. The aim of this study is to evaluate the noise levels generating from tunneling equipments such as jumbo drills, backhoes, payloaders, shotcrete machines and service cars. Explosion and turbo fan noises were also monitored. A high precision sound level meter was introduced for measuring LAeq, LAFmax, LAFmin and LCpeak noises in 5 tunneling work sites that were located in Seoul, Kyunggi-do and Kangwon-do areas with NATM and shield methods. The highest noise was recorded by explosion(151.9 dB LCpeak) followed by jumbo drills of higher than 110 dB(A) LAeq. Backhoe normally generated 90~110 dB(A) LAeq while breaking work of rock showed additional around 5~15 dB(A). Noise exposure levels for payloader and shotcrete machine scored more than 90 dB(A) which might be a source of noise-induced hearing loss. Additional research in revealing noise levels from construction equipments operating in tunneling works may enhance the protection of workers who exposed to noise primarily at the sites.

• Journal of Microbiology and Biotechnology
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• 제16권2호
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• pp.295-298
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• 2006

Actinomycetes are ubiquitous Gram-positive soil bacteria and a group of the most important industrial microorganisms for the biosynthesis of many valuable secondary metabolites as well as the source of various bioconversion enzymes. Cytochrome P450 hydroxylase (CYP), a hemebinding protein, is known to be involved in the modification of various natural compounds, including polyketides, fatty acids, steroids, and some aromatic compounds. Previously, six different novel CYP genes were isolated from a rare actinomycetes called Sebekia benihana, and they were completely sequenced, revealing significant amino acid similarities to previously known CYP genes involved in Streptomyces secondary metabolism. In the present study, these six CYP genes were functionally expressed in Streptomyces lividans, using an $ermE^{*}$ promoter-containing Streptomyces expression vector. Among six CYP genes, two S. benihana CYP genes (CYP503 and CYP504) showed strong hydroxylation activities toward 7-ethoxycoumarin. Furthermore, the recombinant S. lividans containing both the S. benihana CYP506-ferredoxin genes as well as the S. coelicolor feredoxin reductase gene also demonstrated cyclosporin A hydroxylation activity, suggesting potential application of actinomycetes CYPs for the biocatalysts of natural product bioconversion.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2000년도 제15차 학술회의논문집
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• pp.20-20
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• 2000

Back-propagation neural network (BPNN) is the most prevalently used paradigm in modeling semiconductor manufacturing processes, which as a neuron activation function typically employs a bipolar or unipolar sigmoid function in either hidden and output layers. In this study, applicability of another linear function as a neuron activation function is investigated. The linear function was operated in combination with other sigmoid functions. Comparison revealed that a particular combination, the bipolar sigmoid function in hidden layer and the linear function in output layer, is found to be the best combination that yields the highest prediction accuracy. For BPNN with this combination, predictive performance once again optimized by incrementally adjusting the gradients respective to each function. A total of 121 combinations of gradients were examined and out of them one optimal set was determined. Predictive performance of the corresponding model were compared to non-optimized, revealing that optimized models are more accurate over non-optimized counterparts by an improvement of more than 30%. This demonstrates that the proposed gradient-optimized teaming for BPNN with a linear function in output layer is an effective means to construct plasma models. The plasma modeled is a hemispherical inductively coupled plasma, which was characterized by a 24 full factorial design. To validate models, another eight experiments were conducted. process variables that were varied in the design include source polver, pressure, position of chuck holder and chroline flow rate. Plasma attributes measured using Langmuir probe are electron density, electron temperature, and plasma potential.

• 대한공간정보학회지
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• 제24권2호
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• pp.55-62
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• 2016

Economic and social damages are expected due to yellow dust, occurring every year in Korea and risk of citizens is getting higher accordingly. This study acquired tweet data for yellow dust, which had been the greatest since 2009 for 11 days before and after February 23, 2015. After that, it conducted an analysis on the issue words and association rule. Regarding acquired tweet data, the results of analyzing issue words by using open source R, statistics language shows that 'Mask' was ranked to be the highest, followed by health-related issue words. This indicates that people put the priority in the use of mask for keeping their health, as a result of the occurrence of yellow dust, and subsequently, they showed an interest in diseases, caused by yellow dust. In addition, yellow dust-related diseases, 'cold', 'rhinitis', 'flu', 'asthma', 'bronchitis' were found as issue words, revealing that people had a high concern on the disease occurrence of the respiratory system. The analytical results are judged to reflect the citizen's thought effectively in the process of establishing measures for the prevention of yellow dust.

• 한국세라믹학회지
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• 제38권12호
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• pp.1132-1136
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• 2001

생체친화성이 증진된 생체재료를 얻기 위하여 실리콘 원료로 tetraethyl orthosilicate를 사용하여 실리콘이 치환된 hydroxyapatite를 합성하였다. XRD 분석결과 규산이나 다른 인산칼슘염을 포함하지 않는 순수한 hydroxyapatite상 만이 존재하는 것을 확인할 수 있었다. 성분분석 결과 3.32wt% 까지의 실리콘을 함유하였다. $^{29}$ Si MAS NMR 데이터 분석결과 실리콘은 수산화아파타이트의 결정 내에서 규산염 사면체구조를 가지는 것으로 확인할 수 있었다. FT-IR 분석결과 Si 치환 수산화아파타이트에서 수산기가 감소되는 것은 silicate group의 음전하를 보상하기위한 것으로 사료되었다.

• 한국레이저가공학회지
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• 제18권1호
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• pp.12-17
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• 2015

This work performed numerical analysis of electromagnetic field and thermal phenomena occurring in femtosecond laser irradiation of silver nanowires. The local electric field enhancement was computed to calculate the optical energy dissipation as a Joule heating source and the thermal transport was analysed based on the two-temperature model (TTM). Electron temperature increased up to 1000K after 50fs and its spatial distribution became homogeneous after 80fs at the fluence of 100mJ/cm2. The result of this work is expected to contribute to revealing the photothermal effects on silver nanowires induced by femtosecond laser irradiation. Although the highest increase of lattice temperature was substantially below the melting point of silver, the experimental results showed resolidification and fragmentation of the silver nanowire into nanoparticles, which cannot be explained by the photothermal mechanism. Further studies are thus needed to clarify the physical mechanisms.

• The Korean Journal of Physiology and Pharmacology
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• 제23권4호
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• pp.237-249
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• 2019

Confirming the direct link between neural circuit activity and animal behavior has been a principal aim of neuroscience. The genetically encoded calcium indicator (GECI), which binds to calcium ions and emits fluorescence visualizing intracellular calcium concentration, enables detection of in vivo neuronal firing activity. Various GECIs have been developed and can be chosen for diverse purposes. These GECI-based signals can be acquired by several tools including two-photon microscopy and microendoscopy for precise or wide imaging at cellular to synaptic levels. In addition, the images from GECI signals can be analyzed with open source codes including constrained non-negative matrix factorization for endoscopy data (CNMF_E) and miniscope 1-photon-based calcium imaging signal extraction pipeline (MIN1PIPE), and considering parameters of the imaged brain regions (e.g., diameter or shape of soma or the resolution of recorded images), the real-time activity of each cell can be acquired and linked with animal behaviors. As a result, GECI signal analysis can be a powerful tool for revealing the functions of neuronal circuits related to specific behaviors.