• Korean Management Science Review
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• v.28 no.2
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• pp.93-103
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• 2011

This paper has aimed to identify marketing variables which affect physicians' prescription of drug. Based on a literature review this paper derives the three factors (indirect commercial source, direct commercial source, academic information source) of information sources that physicians rely on for medicines, the three factors (research supporting activity, marketing supporting activity, medicine information supporting activity) of promotion activities physicians prefer, and the four factors (indirect quality of medicine, direct quality of medicine, experience of using medicine, price and design of medicine) of prescription criteria physicians use. Then it investigates using canonical correlation analysis whether or not physicians' prescriptions are affected by the information sources, the promotion activities, and the type of physicians. From the canonical correlation analysis this paper derives the meaningful three canonical functions of prescription for drugs. The first function explains the prescription which is insensitive to marketing activities, the second function does the prescription which is sensitive to them, and the final function does the prescription which is not affected by them.

• Proceedings of the Korean Society of Medical Physics Conference
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• 2002.09a
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• pp.23-27
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• 2002

Two $^{192}$ Ir HDR brachytherapy sources were calibrated with a Farmer ionization chamber in air method and in a PMMA cylindrical phantom. The calibration air method used ionization chamber with buildup cap, and 8 variation distances for center-to-center of the source to chamber. In the optimum distance the measured activity, especially for the high activity source, deviation was 0.3% from the activity provided by manufacturer. Calibration with a PMMA cylindrical phantom was less sensitive, and suitable for quick check method with accuracy less than 10%.

• Journal of information and communication convergence engineering
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• v.4 no.2
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• pp.92-96
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• 2006

Hardware for monitoring the water quality using water fleas is developed. Water flea is a frequently used biological sensor for monitoring the water quality. Water fleas quickly respond to the incoming toxic water by changing their activity when they are exposed. By measuring the activity of water fleas, the incoming toxic water is instantly detected. So far the measurement of activity of water fleas has been done with a system equipped with both a light source of LED and a light detector of photo transistor. Water flea itself is, however, sensitive to light resulting in incorrect response and the system has two inconvenient separate parts of the light source and the detector. This paper suggests a system using a CCD camera instead of a light source and a detector. The suggested system processes the image data from the CCD camera in real time without any delay. The developed system becomes a part of the remote water monitoring embedded system.

• Korean Journal of Microbiology
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• v.16 no.4
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• pp.141-147
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• 1978

In order to increase the productivity of cellulolytic enzymes, medium composition and culture conditions were studied. When cellulose powder (Avicel) supplemented with rice straw was used as carbon source, productivity of ${\beta}-glucosidase$ was increased by about 3 times compared with the runs with only cellulose powder as a carbon source. In this case no negative effects on the production of CMC enzyme activity and filter paper activity was found. For the production of celulolytic enzymes using T. reesei QM 9414, casitone was found to be a good nitrogen source compared with other sources studied, such as peptone, yeast extract, tryptone, and casein. The highest cellulase activity was attained when 0.3% glucose and 0.01% Tween 80 were supplemented to the standard medium of Rese. An adequate oxygen transfer rate was also found to be important to the cellulase fermentation and about 50 mmole of oxygen/liter/hour supported good cellulase biosynthesis during cellulase fermentation.

• Journal of Microbiology and Biotechnology
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• v.14 no.3
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• pp.532-539
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• 2004

For efficient lincomycin production from Streptomyces lincolnensis L1245, various vegetable oils, natural nitrogen sources, and surfactants were investigated at the pilot-scale level in the flask. Olive oil as the sole carbon source was the most suitable one for producing lincomycin. When 20 g/lof olive oil was used, the lincomycin concentration and lipase activity reached 1.01 g/land 182 U/ml, respectively, after 5 days of culture. Among the various unsaturated fatty acids, when linolenic acid was used, the cell growth and lincomycin production were markedly decreased. On the other hand, when 0.2 g/l of oleic acid was added to the culture broth, the maximum lincomycin concentration was 1.0 g/l, which was about 1.7-fold higher than that obtained without the addition of oleic acid. Among the various natural nitrogen sources, pharmamedia or soybean meal was the most suitable nitrogen source. In particular, in the case of a mixture of 10 g/l of pharmamedia and soybean meal, 1.5 g/l of lincomycin concentration and 220 U/ml of lipase activity were obtained. When Span 180 was used as the surfactant, lincomycin production, lipase activity, and oil consumption increased. The correlation between the consumption rates of oil and lincomycin production in a culture using olive oil as the sole carbon source was also investigated. The lincomycin production depended on the consumption rate of olive oil. Using these results, fed-batch cultures for comparing the use of olive oil and starch as a conventional carbon source were carried out in a 5-1 fermentor. When olive oil was used as the sole carbon source, 34 g/l of olive oil was consumed after 7 days of culture. The maximum lincomycin concentration was 3.0 g/l, which was about 2.0-fold higher than that of starch medium after 7 days of culture. The product yield was 0.09 gig of consumed carbon source, which was about 3.0-fold higher than that of starch medium after 7 days of culture.

• Journal of Ecology and Environment
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• v.43 no.1
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• pp.1-8
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• 2019

Background: Hibernating bats exhibit ubiquitous winter activity in temperate zones, but there is considerable between- and within-species variety in their intensity and purpose. Bats may fly during winter for sustenance or travel to other hibernacula. This study compared inter-regional variation in the winter activity of the greater horseshoe bat (Rhinolophus ferrumequinum). We predicted that weather and hibernacula-environmental conditions would influence winter activity patterns. Results: Winter activity patterns differed between regions. In the Anseong area, we confirmed movement inside the hibernaculum, but in Hampyeong, we observed movement both inside and between hibernacula. The two regions differ by $4^{\circ}C$ in average winter temperatures. Anseong experiences 22 days during which average daily temperatures exceeded $5^{\circ}C$, whereas Hampyeong experienced 50 such days. During the hibernating period, bat body weight decreased by approximately 17-20% in both regions. Conclusions: Ambient temperatures and winter-roost environments appear to be behind regional differences in hibernating bat activity. As winter temperatures in Korea do not favor insect activity, feeding probability is low for bats. However, bats may need to access water. At Anseong, underground water flows inside the hibernaculum when the reservoir outside is frozen. At Hampyeong, the hibernaculum does not contain a water source, but the reservoir outside does not freeze during winter. In conclusion, water-source location is the most likely explanation for regional variation in the winter activity of hibernating bats.

• Journal of the Korean Society of Earth Science Education
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• v.5 no.3
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• pp.307-315
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• 2012

The purpose of this study was to examine the effects of small inquiry method on space perception ability and creative personality. Testees of this research are 36 elementary pre-service teachers taking an astronomical observation class. Doing inquiry activity after 36 elementary pre-service teachers are classified into 6 Jigsaw small inquiry. Learning activity was split into two groups, expert group and a population. To find out research outcome, pre-test was executed space perception ability test, creative personality test. Analysis of test result was accomplished with statistical package SPSS 18.0 paired t testing hypothesis. The results of this study are as follows. First, 'source of season change' class using Jigsaw small inquiry method has effect on space perception ability improvement. This was interpreted that space perception ability improvement was effective because characteristic of Jigsaw small inquiry is made up of lots of semin Second, 'source of season change' class using Jigsaw small inquiry method has no effect on creative personality. This was interpreted that experiment and discussion activity getting accomplished in a short time has no effect on qualitative characterizing Creative Personality improvement.

• Progress in Superconductivity
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• v.4 no.1
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• pp.48-52
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• 2002

When applying a SQUID system for diagnosing heart disease, it is informative to obtain the source current distributions from the measured MCG (magnetocardiogram) signals since the bioelectric activity in the heart is generally represented by distributed current sources. In order to estimate the Primary current distribution in a heart, the minimum norm estimate was computed, assuming a source plane below the chest surface. In the simulation, current distributions, which were computed for the test dipoles represented well the essential feature of the test-current configurations. Source current reconstruction was performed for MCG signal of a healthy volunteer, which was recorded using a 40-channel SQUID system in a magnetically shielded room. It was found that the obtained current distribution is consistent with the electrical activity in a heart.

• Natural Product Sciences
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• v.3 no.2
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• pp.106-107
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• 1997

Indole-3-methylethanoate was isolated for the first time form natural source i.e. from the leaves of Camellia sinensis (L.) O. Kuntz and fully characterized by physical and chemical evidence, the biological activity of the compound was studied by wheat coleoptile bioassay which showed growth promoting activity.

• Convergence Security Journal
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• v.3 no.2
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• pp.41-55
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• 2003

Today the traditional national intelligence activities which are mainly based on classified informations are confronted with several problems. These are excessive collection cost, morality of intelligence activity, objectivity of intelligence, intelligence dead zone and timeliness of intelligence etc. On the other hand, circumstances of national intelligence activity are rapidly changed. Those are rapid growth of internet, transformation of classified information into open one and rapid growth of intelligence capabilities of private sector. To cope these problems and circumstances, we reevaluated OSINT(Open Source INTelligence) which is collected from all kinds of open source informations on the internet. First, we classified OSINT into four categories corresponding to the traditional classified collection methods i.e., IMINT, SIGINT, HUMINT and MASINT. And we evaluate the value of OSINT in comparison with classified collection methods. Finally a system for national intelligence activity based on all kinds of open source intelligence on the internet is proposed, described and compared with the system of traditional national intelligence activity.