• Biomolecules & Therapeutics
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• v.4 no.4
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• pp.419-427
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• 1996

To solubilize practically insoluble biphenyl dimethyl dicarboxylate (DDB), which has been used for the treatment of chronic hepatitis as tablets or hard capsules, the solubilities of DDB in various hydrophilic, oily and hydrocarbon vehicles, and aqueous surfactant solutions were measured by high performance liquid chromatography. It was found that, among the vehicles studied, polyethylene glycol (PEG) 300 revealed the best solvency, and the solubility reached 17.6 mg/ml at 37$^{\circ}C$. The addition of glycyrrhizic acid ammonium salt (GAA) to DDB-PEG 300 solution (5-20 mg/g) inhibited the formation of precipitates, and at the concentration of 10 mg/g, any precipitaction was not observed even after 2 years at 4$^{\circ}C$. Furthermore, GAA markedly enhanced the permeation of DDB through the rabbit duodenal mucosa in a concentration dependent manner. The addition of copolyvidone (ca. 1.0%) to DDB-GAA-PEG 300 system (1 : 0.5 97.5 w/w) was most effective in preventing the considerable precipitation of DDB-PEG 300 solution (7.5 mg/750 mg) when mixed with water of 300-900 ml at 37$^{\circ}C$. GAA showed a synergistic effect in the prevention of precipitate formation. This finding suggests that this DDB formulation may form less precipitation when DDB soft capsules disintegrate and diffuse into the gastrointestinal fluid, resulting in improving the bioavailability Dissolution rate of DDB (7.5 mg) from sort elastic capsules of DDB-GAA-PEG 300 system was rapid. The supersaturation state was maintained for 2 hr at the concentration of 7.35$\pm$3.3 mg in 900 ml of water without precipitation. The total amount of DDB dissolved from this new formulation was 5.3 and 6.1 times higher, when compared to marketed DDB tablets (25 mg) and capsules (7.5 mg), respectively.

• The Journal of Korean Medical History
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• v.25 no.1
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• pp.11-22
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• 2012

This study is about King Kyung-jong's medical history written on "The Daily Records of Royal Secretariat of Chosun Dynasty". Kyung-jong, the 20th King of Chosun was born in 1688 as a prince and passed away in 1725. When he was prince, his main diseases were some infectious things; for example, smallpox, measles, a sort of malaria, a sort of mumps etc. But the time he was king, his main diseases were related unenergetic(虛證). According to "The Daily Records of Royal Secretariat of Chosun Dynasty" yak-bang(藥房) records, some informations about his health are different from general knowledges. At first, His father's dead is more related his health than his mother's dead. Second, he was fat, not thin(or desiccate). Third, his infertility was not caused his mother when she died. Fourth, he was regarded as one of psychological healthy person. And not exactly related Kyung-jong's health, in "The Daily Records of Royal Secretariat of Chosun Dynasty" at Kyung=jong's era, there are some meaningful informations at medical history. One is a doctor who was smallpox specialist. His name is Yoo-Sang, he treated three of Chosun's King very perfectly and his family worked for the royal family's health for 150 years, especially treating smallpox. the other is prescription Gamijojungtang(加味調中湯), Kyung-jong's favorite prescription. This prescription is considered royal special prescription at Chosun.

• Journal of The Korean Association For Science Education
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• v.15 no.3
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• pp.291-302
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• 1995

Most middle school and high school students learns under the same study plans and educational courses. Such an equal level education policies prevent the science-gifted from developing and promoting their ability. So it is severely necessary to sort out the gifted in science and make them develop their ability. In this paper, the attitudes of teachers and parents toward the science-gifted student in middle school were investigated as well as the characteristics of the gifted. One hundred science teachers of middle school who recommended the gifted in science and their parents in Seoul area were questionnaired. The follows are the consequences of investigation. 1. Most teachers and parents of the gifted considered that the school should do a special care for the gifted in science. That is, they prefer the enrichment course to the acceleration course for it. 2. The teachers play the role of motivating the study and promotion very well, but do not well as either the advisor or the cooperator with the parents because of their excessive work and lack of professional knowledgement about education of the gifted. 3. The parents play the role of the advisor or the counselor well, but do not well as the cooperator with school. 4. Among the characteristics of the gifted, there are not any differences between boys and girls in conduct characteristics. But there are meaningful difference in emotion characteristics. 5. The education of the gifted is very important for developing of country and personal promotion. So the administrative and financial support are necessary in order to sort out the gifted in science earlier and provide various programs.

• Journal of architectural history
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• v.18 no.1
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• pp.7-29
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• 2009

In understranding the essence of the Korea traditional Architecture, it is important to consider the jointing methods of architectural members, architectural technologies, etc. Especially the purpose of this study is understanding on the Jointing Method of Wooden Members in the period of Unified Silla Architecture. It's conclusion is summarized as follows. 1. A section of column has very close to do with the foundation stone. The structures of foundation stone and column are generally concluded by butt joint, arrow-head joint, housed joint by Grang-e method. Judu is structured by arrow-head joint And, in general, beam is structured by Sagaematchum Chumcha and sagaljudu of Don direction. At the head of Pyungju and the body of Goju, Changbang is structed by Jangbumachum with arrow-head joint or by jumukchang-machum. Also, it is surmised that Gyisoseum and Anssolim methods had been applied to columns from former ages. The example can be found at Bagjae Mireuksaji stone pagoda. Bagjae Mireuksaji stone pagoda taking wooden-pagoda form adopts Gyisoseum and Anssolim methods. We can also find such a sort of methods from other stone constructions like Budo, etc. 2. Injahwaban is structured by short Changbumachum with arrowed-head joint at upper members, and by Anjangmachum at the lower part. This sort of Gongpo style can be seen in the mural painting of tomb of Koguryo and in Buplyungsa, Buplyunsa, Bupkisa-located in Japan, which are influenced by Bakjae or Unified Silla. It is considered that at the end of the late United Silla, Injawhaban had been replaced with Chumcha and Soro on the Pyungbang under influence of Dapo style from China.

• Journal of Fisheries and Marine Sciences Education
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• v.28 no.5
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• pp.1358-1364
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• 2016

Maritime accidents caused by a ship include collisions, sinking, stranding and fire etc. This study is intending to consider fire accidents among such diverse marine accidents. It is much likely that various sorts of fires break out because crewmen are living in a narrow space for long periods of time consequent on the ship's characteristic of sailing on the sea. According to the ship fire survey, about 50% of the total fire accidents occurred at an engine room, and the main fire origin was analyzed to be oil. In addition, ship fire breaks out in the order of baggage racks and living quarter. In short, the survey indicates that all sorts of fires belonging to A, B, C and D-class have occurred. This study, targeting an actual passenger ship 'A', found the response time to evacuation, during which the people on board a ship recognize the outbreak of fire, and act, and the travel time for evacuation which is the actual travel time. In addition, this study carried out a simulation through the special program for fire analysis - FDS (Fire Dynamics Simulator) in order to find the effective evacuation time, i.e. life survival time. Particularly, this study did comparative analysis of the influence on the survival of passengers and crew based on the collected simulation data by fire size and sort. As a result of the analysis, it was found that when examining the only actual evacuation movement time excepting the response time to evacuation, people are safe by completing evacuation before the effective evacuation time only in case fire size is 100Kw among all sorts of fires. In other words, in case of the outbreak of fire more than 1 MW, it was found to fail to meet evacuation safety regardless of fire size.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.42 no.3 s.303
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• pp.9-16
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• 2005

For designing the database more efficiently, normailzation can be enforced to minimize the degree of unnecessary data redundancy and contribute to enhance data integrity. However, deep normalization tends to provoke multiple way of schema join, which could then induces response time degradation. To mitigate this sort of side effect that the normalization could brought, a number of field studies we observed adopted the idea of denormalization. To measure whether denormalization contributes to response time improvement, we in this paper developed two different data models about customer service system, one with perfect normalization and the other with denormalization, and evaluated their query response time behaviors. Performance results show that normalization case consistently outperforms denormalization case in terms of response time. This study show that the idea of denormalization, quite rarely contributes to that sort of improvement due ironically to the unnecessary data redundancy.

• Journal of the Korean Institute of Landscape Architecture
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• v.31 no.6
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• pp.95-103
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• 2004

A turfgrass rootzone foundation is one of the important iufluences on the growth of cool-season turfgrass such as Kentucky bluegrass, which is usually grown on korean golf courses and athletic fields in Korea. This study was carried out to evaluate the growth of Kentucky bluegrass on 4 types of turfgrass root-zone foundations: a 2cm thickness of Sand 90%+Peat humus 8%+Zeolite 2% mixture on a subsoil base (C), a 20cm thickness of Sand 90%+Peat humus 8%+Zeolite 2% mixture (S), a 20cm thickness of Sand 45%+fine sand(a sort of Bomyungsa) 45%+Peat humus 8%+Zeolite 2% mixture (S+F), and a 20cm thickness of Sand 45%+fine sand(a sort of Bomyungsa) 45%+Peat humus 8%+Zeolite 2% mixture on a 20cm thick drainage layer (S+F(G)). Visual ratings of Kentucky bluegrass on the C foundation were low throughout the experiment when compared to S, S+F, and S+F(G) foundations, which contained high contents of sand with a high water infiltration rate. However, poor growth of Kentucky bluegrass in the summer of 1991 on the S foundation was likely to be caused by a too high water infiltration rate (185.8cm/hr). The growth of Kentucky bluegrass on the S+F(G) was good while the growth was a little weak at the developing stage on the S +F foundation. If the cost had to be considered when constructing golf courses and athletic fields, The S+F foundation without the drainage layer would be the best choice in terms of low cost and good quality of Kentucky bluegrass compared to the S+F(G). In this result, the infiltration rate was regarded as the most influential factor to the growth of Kentucky bluegrass on rootzone foundations.

• Korean Institute of Interior Design Journal
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• v.18 no.1
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• pp.3-10
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• 2009

The relationship between light and space is fundamental In an opera stage design. In contemporary stage design, light, color and space themselves became one of tile most important elements to express and symbolize the content of the opera. This was very different compared to the primitive and medieval opera stage design in the past. The designer tried to represent the same periodical background of the opera with exact replica of the buildings as well as costumes. In comtemporary performance art, light became one the most important aspects in design. Max Keller is one of the living pioneers in stage lighting design. This thesis that is based on his lighting experiments and projects attempts to examine how contemporary stage design and light are applied and what kind of characteristics they have. One of the Wagner's opera, "Tristan und Isolde" was selected to be further analyzed. Three different "Tristan und Isolde" opera stage designs were carefully studied in terms of how three designs are differently constructed for specific same contents of the opera. This sort of comparison study is crucial when there is a strict parameter that is the opera itself. It was found that three opera stages have very different stage designs and unique ways of expressing the opera flow and contents. However, in some parts, very similar lightings were used. This sort of multi-disciplinary study can be helpful to re-think the interior environment by applying light as a fundamental medium.

• Journal of the Korea Institute of Building Construction
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• v.21 no.5
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• pp.397-408
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• 2021

The construction industry has the highest occupational accidents/injuries and has experienced the most fatalities among entire industries. Korean government installed surveillance camera systems at construction sites to reduce occupational accident rates. Construction safety managers are monitoring potential hazards at the sites through surveillance system; however, the human capability of monitoring surveillance system with their own eyes has critical issues. A long-time monitoring surveillance system causes high physical fatigue and has limitations in grasping all accidents in real-time. Therefore, this study aims to build a deep learning-based safety monitoring system that can obtain information on the recognition, location, identification of workers and heavy equipment in the construction sites by applying multiple object tracking with instance segmentation. To evaluate the system's performance, we utilized the Microsoft common objects in context and the multiple object tracking challenge metrics. These results prove that it is optimal for efficiently automating monitoring surveillance system task at construction sites.

• The Journal of the Korea Contents Association
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• v.21 no.7
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• pp.404-412
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• 2021

This study was conducted by using the Q research method, one of the qualitative analysis methods, in order to approach consumers' perceptions of processed meat food in an essential and in-depth approach. To this end, Q-sort, which goes through the task of distributing responses by setting P samples by creating a question-and-answer table of positive and negative, was analyzed by using the PC QUANL program and analyzing the Q factor. As a result of the analysis, it was divided into three single types. Type 1 (N= 10) : Preferred types of processed meat food, Type 2 (N= 7) : Types of Pursuing Functionality of Processed Meat Food, Type 3 (N= 4) : The name of the factor was set as the non-preferred type of processed meat food. Each type has different characteristics, and the subjective perception of each factor detected through this analysis can be used as various basic research data in the future, and for the purpose of the study, the perceptions of consumers who use processed meat foods were classified and classified by type. It is to suggest future improvement directions by checking the characteristics of the variables.