• Proceedings of the Korean Society of Medical Physics Conference
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• 2004.11a
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• pp.122-125
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• 2004

In radiotherapy of tumors in liver, enough planning target volume (PTV) margins are necessary to compensate breathing-related movement of tumor volumes. To overcome the problems, this study aims to obtain patients' body movements by using a moving phantom and an ultrasonic sensor, and to develop respiration gating techniques that can adjust patients' beds by using reversed values of the data obtained. The phantom made to measure patients' body movements is composed of a microprocessor (BS II, 20 MHz, 8K Byte), a sensor (Ultra-Sonic, range 3 cm ${\sim}$3 m), host computer (RS232C) and stepping motor (torque 2.3Kg) etc., and the program to control and operate it was developed. The program allows the phantom to move within the maximum range of 2 cm, its movements and corrections to take place in order, and x, y and z to move successively. After the moving phantom was adjusted by entering random movement data(three dimensional data form with distance of 2cm), and the phantom movements were acquired using the ultra sonic sensor, the two data were compared and analyzed. And then, after the movements by respiration were acquired by using guinea pigs, the real-time respiration gating techniques were drawn by operating the phantom with the reversed values of the data. The result of analyzing the acquisition-correction delay time for the three types of data values and about each value separately shows that the data values coincided with one another within 1% and that the acquisition-correction delay time was obtained real-time (2.34 ${\times}$ 10$^{-4}$sec). This study successfully confirms the clinic application possibility of respiration gating techniques by using a moving phantom and an ultra sonic sensor. With ongoing development of additional analysis system, which can be used in real-time set-up reproducibility analysis, it may be beneficially used in radiotherapy of moving tumors.

• Journal of the Korean Geosynthetics Society
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• v.18 no.4
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• pp.115-127
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• 2019

The low-flow grouting injection technique, the target construction method for this study, is a method of pouring mortar into the ground by non-emission replacement principle, which can be expected to increase the density of the ground, and, in some cases, be used as a base file using the strength of the high injection solids, along with low noise, low pollution, and high durability. To verify that the dynamic characteristics of the ground are improved by the low-flow injection technique, the test work was conducted on the site and physical tests were performed, and the quality of the improvement formed in the ground was verified through the indoor test on the core and core recovery rate was analyzed. The density logs test layer calculated the volume density of the ground layer by using the Compton scattering of gamma-rays, and the sonic logs was tested on the ground around the drill hole using a detector consisting of sonar and receiver devices inside the drill hole. As a result of the measurement of the change in physical properties (density and sonic logs) before and after grouting, both properties were basically increased after infusion of grout agent. However, the variation in density increase was greater than the increase in speed after grouting, and the ground density measurement method was thought to be effective in measuring the fill effect of the filler. Strength and core recovery rates were measured from specimens taken after the age of 28 days, and the results of the test results of the diffusion and strength test of the improved products were verified to satisfy the design criteria, thereby satisfying the seismic performance reinforcement.

• Journal of the Korea institute for structural maintenance and inspection
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• v.21 no.5
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• pp.94-100
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• 2017

In the case of the side scan sonar operated by the towing method, the underwater structure electric jig was developed because there is a difficulty in the cross-sectional survey that the user wants when conducting the survey. However, in the case of the sound wave photographing method using the electric jig, since the boat and the sonar behaves as one body, data distortion has occurred due to various problems according to working environment, such as, the rolling phenomenon of the boat due to the wave and the fluctuation of the sonic image due to the inoperability of the boat driver. Therefore, in order to solve the image blurring caused by the operation of the equipment for underwater survey of the existing side scan sonar, in this research, the program was supplemented to enable the shake correction by attaching the shake correction sensor and developing the shake correction algorithm. In order to verify the improvement of the sonar data resolution, the sonic images before and after the shake correction were collected through on-site investigation and the analysis of the sonic image data acquired by a diver measuring the actual damage length and depth. This study is expected to contribute to the development of sonar imaging technique of the underwater surface of the structure and bed surface of the sea or a river using the side scan sonar in the future.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.2
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• pp.437-442
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• 2015

Aim: To establish a pancreatic cancer stem cell model using human pancreatic cancer cells in nude mice to provide a platform for pancreatic cancer stem cell research. Materials and Methods: To establish pancreatic cancer xenografts using human pancreatic cancer cell line SW1990, nude mice were randomly divided into control and gemcitabine groups. When the tumor grew to a volume of $125mm^3$, they treated with gemcitabine at a dose of 50mg/kg by intraperitoneal injection of 0.2ml in the gemcitabine group, while the mice in control group were treated with the same volume of normal saline. Gemcitabine was given 2 times a week for 3 times. When the model was established, the proliferation of pancreatic cancer stem cells was observed by clone formation assay, and the protein and/or mRNA expression of pancreatic stem cell surface markers including CD24, CD44, CD133, ALDH, transcription factors containing Oct-4, Sox-2, Nanog and Gli, the key nuclear transcription factor in Sonic Hedgehog signaling pathway was detected by Western blot and/or RT-PCR to verify the reliability of this model. Results: This model is feasible and safe. During the establishment, no mice died and the weight of nude mice maintained above 16.5g. The clone forming ability in gemcitabine group was stronger than that of the control group (p<0.01). In gemcitabine group, the protein expression of pancreatic cancer stem cell surface markers including CD44, and ALDH was up-regulated, the protein and mRNA expression of nuclear transcription factor including Oct-4, Sox-2 and Nanog was also significantly increased (P<0.01). In addition, the protein expression of key nuclear transcription factor in Sonic Hedgehog signaling pathway, Gli-1, was significantly enhanced (p<0.01). Conclusions: The pancreatic cancer stem cell model was successfully established using human pancreatic cancer cell line SW1990 in nude mice. Gemcitabine could enrich pancreatic cancer stem cells, simultaneously accompanied by the activation of Sonic Hedgehog signaling pathway.

• Geophysics and Geophysical Exploration
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• v.12 no.1
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• pp.154-162
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• 2009

Sonic wave dispersion characteristics are one of the most important targets of study, particularly in estimating shear wave velocity from borehole sonic logging. We have tested dispersion characteristics using monopole and dipole sources. Theoretical dispersion curves were computed for tool-absent and tool-included models having the same physical properties but different diameters (including ${\Phi}520mm$, ${\Phi}150mm$, and ${\Phi}76mm$). Comparisons were made between boreholes of different sizes and between tool-absent and tool-included models. Between the tool-included and the tool-absent boreholes, a close similarity in dispersion curve shape was revealed for the monopole source, and a significant difference was shown for the dipole source. However, for the cut-off frequency, particularly in the engineering boreholes (${\Phi}76mm$ and ${\Phi}50mm$), a significant difference was observed for signals from the monopole source, but approximately the same cut-off frequencies were found with the dipole source. This indicates the need of careful choice of source frequency in monopole-source sonic logging, particularly in an engineering borehole. The results of numerical experiments show that cut-off frequency is exponentially proportional to the inverse of borehole radius, irrespective of the mode type and the presence of a tool, and that the cut-off frequencies for each borehole environment could be expressed as an exponential function, rather than the inversely proportional relationship between the cut-off frequency and the borehole radius that was previously generally recognised. From the direct comparison of dispersion curves, the effects on the dispersion characteristics of borehole size and the presence of the tool can be revealed more clearly than in previous studies, which presented the dispersion curve and/or characteristics for each borehole environment separately.

• Geophysics and Geophysical Exploration
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• v.26 no.3
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• pp.138-149
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• 2023

In geoscience and engineering the geological characteristics of sediment strata is crucial and possible if reliable borehole logging and seismic data are available. To investigate the characteristics of the shallow strata in the Korea Strait, laboratory sonic logs were obtained from deep borehole data and seismic section. In this study, we integrated and analyzed the sonic log data obtained from the drilling core (down to a depth of 200 m below the seabed) and multichannel seismic section. The correlation value was increased from 15% to 45% through time-depth conversion. An initial model of P-wave impedance was set, and the results were compared by performing model-based, band-limited, and sparse-spike inversions. The derived P-impedance distributions exhibited differences between sediment-dominant and unconsolidated layers. The P-impedance inversion process can be used as a framework for an integrated analysis of additional core logs and seismic data in the future. Furthermore, the derived P-impedance can be used to detect shallow gas-saturated regions or faults in the shallow sediment. As domestic deep drilling is being performed continuously for identifying the characteristics of carbon dioxide storage candidates and evaluating resources, the applicability of the integrated inversion will increase in the future.

• Journal of the Korean Academy of Esthetic Dentistry
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• v.7 no.1
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• pp.72-78
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• 1998

Recently, esthetic dentistry has been developed because beauty is pursued by both dentists and patients. A scope of esthetic treatment has been expanded and the roles of hygienists in dental treatment have also become of importance. Generally, we make use of the ultra-sonic scaler to remove the stains attached to teeth surfaces, but when we utilize the rubber cup and pumice in prophylaxis, this increases the hypersensitivity, patient's anxiety, and chairtime. So, we substitute Air-polishing that increases patient's satisfaction and decreases chairtime for above method, Here, I would like to explain indications and contraindications, advantages and disadvantages, and usages of Air-polilshing briefly.

• 한국생물공학회:학술대회논문집
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• 2005.04a
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• pp.264-267
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• 2005

The purpose of this study was to investigate the ultra sonic extraction method of phenolic compounds and antioxidant activity from Rumex crispus. Rumex crispus was fractionated with hexane, ethyl acetate, butanol and water. The amount of phenol compounds and antioxidant activity was presented higher content in ethyl acetate fraction then others.

• Proceedings of the Korea Concrete Institute Conference
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• 2001.05a
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• pp.795-800
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• 2001

Two evaluation techniques of the tunnel lining concrete using ultra sonic velocity method are developed. Modified linear regression technique is proposed to enhance the corelation between the pulse velocity and the compressive strength of core specimens. And bivariate normal distribution is assumed to evaluate the quality of concrete as a terms of compressive strength. A simple corelation table between the pulse velocity and the compressive strength of core specimens are proposed.

• Proceedings of the Korea Society of Design Studies Conference
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• 2004.10a
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• pp.164-165
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• 2004