• 제목/요약/키워드: Soma

검색결과 93건 처리시간 0.023초

흰쥐의 턱끝혀근 지배 운동신경원에 대한 억제성 및 흥분성 신경종말의 분포 양식 (Distribution Pattern of Inhibitory and Excitatory Nerve Terminals in the Rat Genioglossus Motoneurons)

  • 문용석
    • 생명과학회지
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    • 제21권1호
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    • pp.102-109
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    • 2011
  • 턱끝혀근은 호흡을 위해 상부기도를 확보하는 중요한 근육이지만 정상적으로 수축하지 못하면 상부기도를 폐쇄함으로써 호흡장애가 생길 수있다. 이것은 턱끝혀근을 지배하는 운동신경원의 연접입력 이상으로 생각하고 있으나 이러한 연접입력에 대해서는 잘 알려져 있지 않다. 본 연구에서는 흰쥐의 턱끝혀근을 지배하는 운동신경원과 연접하는 억제성 및 흥분성 신경종말의 분포 양식에 대해 분석하고자 하였으며, 이를 위해 신경추적자인 HRP를 주입하여 턱끝혀근 지배 운동신경원을 표식하고, 운동신경원을 세포체와 가지돌기의 근위부, 중간부 및 원위부로 구분한 후, 전자현미경용 연속절편을 제작하여 GABA, glycine 및 glutamate 항체를 사용한 postembedding immunogold histochemistry를 시행하였다. 정량적 분석은 3개의 턱끝혀근 운동신경원에 연접한 622개의 신경종말 중 157개는 세포체에서, 188개는 14개의 가지돌기 근위부에서, 181개는 35개의 가지돌기 중간부에서, 96개는 28개의 가지돌기 원위부에서 각각 연접 양상을 분석하였다. 관찰한 신경종말의 71.9%에서 사용된 3종류의 아미노산에 대한 면역양성반응이 나타났는데 이 중 32.8%는 GABA 또는 glycine에 대한 면역양성반응을 보였고, 39.1%는 glutamate에 대한 면역양성반응을 보였다. GABA 또는 glycine에 대한 면역양성 신경종말 중 14.2%는 glycine에만 면역양성반응을 보였고, 13.3%는 glycine과 GABA에 동시에 면역양성반응을 보였으며, 5.3%만이 GABA에만 면역양성반응을 보였다. 억제성 아미노산에 면역양성반응을 보인 신경종말에는 납작하거나, 타원형 또는 둥근 형태의 연접소포가 함유된 반면, 흥분성 아미노산에 면역양성반응을 보인 신경종말에는 구형의 소포와 약간의 큰 치밀연접소포가 함유되어 있었다. 억제성 신경종말과 흥분성 신경종말의 분포 비율은 가지돌기 원위부에서 각각 23.9% 대 43.8%로 가장 높았지만, 세포체(35.7% 대 38.2%), 가지돌기의 근위부(34.6% 대 37.8%), 및 중간부(33.1% 대 38.7%)에서는 큰 차이를 보이지 않았다. 억제성 신경종말의 synaptic covering (%)은 세포체에서 가지돌기 원위부로 갈수록 감소되었지만, 흥분성 신경종말의 synaptic covering (%)은 각 부위에서 큰 차이를 나타내지 않았다. 본 연구를 통하여 턱끝혀근 지배 운동신경원은 세포체와 가지돌기의 부위에 따라 GABA, glycine 및 glutamate를 함유하는 전운동신경원들에 의해 서로 다른 양식의 제어를 받고 있다는 것을 알 수 있었으며, 운동신경원의 부위에 따른 이러한 억제성 및 흥분성 연접입력 양식의 차이는 유연한 혀운동의 제어기전과 밀접한 관련이 있을 것으로 추정된다.

들로네(S. Delaunay)의 직물디자인에 나타난 리듬과 색채에 관한 연구 (A Study on Rhythm and Color expressed in S. Delaunay′s Textile Design)

  • 정혜정
    • 복식
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    • 제50권6호
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    • pp.47-58
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    • 2000
  • This paper analyses the geometric aspect of Soma Delaunay's works on the basis of design elements and principles. Geometric pattern is one of the distinct features of early 20th century avant-garde works. The significance of its pattern and colour comes from the fact that it has not only influenced the contemporary fine art but also offered the basic principle of modern costume design. In 1925 she was designing clothes which could be worn today without appearing old-fashioned. She foresaw the future trends in fashion and interior decoration, One might claim she belongs to the avant-garde even today and no less astonishing a phenomenon than she was in 1925. Soma Delaunay's art was one of the first expressions of abstract painting and her "simultaneous contrasts"are among the earliest example of the aesthete. In Delaunay's geometric abstraction it is found that the technique of"simultaneous contrasts" is exploited almost without exception. colour as well as collage was the favourite technique Delnaunay used in creating a distinct simultaneity, Many "inobjective" paintings as she herself called unite the rigour of simple geometric forms with an inner life and poetry which emanate from the richness of the colour, the musicality of the rhythm, the vibrant breadth of the execution.rant breadth of the execution.

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Design of a Neural Chip for Classifying Iris Flowers based on CMOS Analog Neurons

  • Choi, Yoon-Jin;Lee, Eun-Min;Jeong, Hang-Geun
    • 센서학회지
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    • 제28권5호
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    • pp.284-288
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    • 2019
  • A calibration-free analog neuron circuit is proposed as a viable alternative to the power hungry digital neuron in implementing a deep neural network. The conventional analog neuron requires calibrations because a voltage-mode link is used between the soma and the synapse, which results in significant uncertainty in terms of current mapping. In this work, a current-mode link is used to establish a robust link between the soma and the synapse against the variations in the process and interconnection impedances. The increased hardware owing to the adoption of the current-mode link is estimated to be manageable because the number of neurons in each layer of the neural network is typically bounded. To demonstrate the utility of the proposed analog neuron, a simple neural network with $4{\times}7{\times}3$ architecture has been designed for classifying iris flowers. The chip is now under fabrication in 0.35 mm CMOS technology. Thus, the proposed true current-mode analog neuron can be a practical option in realizing power-efficient neural networks for edge computing.

배추흰나비 (Pieris rapae L.) 뇌간부(腦間部)의 신경세포(神經細胞)에 대한 미세구조(微細構造) (Ultrastructure of Nerve Cells in the Pars Intercerebralis of Cabbage Butterfly Pieris rapae L.)

  • 이봉희;김우갑
    • Applied Microscopy
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    • 제12권2호
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    • pp.55-68
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    • 1982
  • The study on the nerve cells in the pars intercerebralis(IP) of 5-day-old cabbage butterfly Pieris rapae L. was performed to observe their ultrastructures and classify them on the basis. of the differences in size, shape and relative distribution cf cell organelles. The brain-subesophageal ganglion complex was fixed in 1% paraformaldehyde-1% gluaraldehyde mixture and embedded in araldite mixture. The transverse thin sections of IP were stained with uranyl acetate and lead citrate and examined by Hitachi 500 and ]EM 100B electron microscope. Five distinct types. of nerve cells are recognized and are arbitrarily designated as Type I, Type II Type III, Type IV and Type V. Type I neurone: These neurones are neurosecretory cells. Several neurosecretory cells are. recognized in the pars intercerebralis. They are roughly round or peach-shaped cells measuring $13{\sim}25{\mu}m$ in diameter. The rounded nucleus shows about $5{\sim}10{\mu}m$ in diameter. The chromatin is predominantly diffused with only occasional dense patches. The perikaryon contains numerous. mitochondria, free polyribosomes and neurosecretory granules. The neurosecretory granules are relatively uniform in electron density, and each one is about $100{\sim}400{\mu}m$ in diameter and surrounded by a single membrane. The granules are also observed mostly as in groups. In one group of neurones the cisternae of endoplasmic reticulum are distended or in other group of neurones are not distended. Golgi saccules are slightly dilated at their lateral extremities and contains. frequenty dense rounded materials. Type II neurone: Thes have the largest soma in the pars intercerebralis about $30{\sim}35{\mu}m$ in diameter. They also show roughly polygonal in shape. The nucleus is elongated or sickle-shaped. The chromatin is mainly in the euchromatin form. The perikarya in these cells are well populated with populated with free ribosomes and contain numerous mitochondria and Golgi bodies. The cisternae of granular endoplasmic reticulum are also well distributed. Type III neurone: They are oval or spindle-shaped and also medium-sized. neurones approximately $15{\sim}17{\mu}m$ in length. The nucleus is oval or slightly elongated in shape and $8{\sim}9{\mu}m$ in length. The chromatin occurs in diffused form. The cytoplasm contains many filamentous or oval mitochondria. The perikaryon has also numerous free polyribosomes and cisternae of granular endoplasmic reticulum. Type VI neurone: They are roughly polygonal in shape probably due to the close approximation of the adjacent cells. The soma is about $7{\sim}8{\mu}m$ in diameter. The nucleus is round or oval in shape and $5.0{\sim}5.8{\mu}m$ in diameter. The necleus also occupies a large proprion of the cell body. The perikaryon is well populated with free ribosomes and contains several mitochondria and cistenae of granular endoplasmic reticulum. Type V neurone: These neurones are similar to Type VI neurones in various respects such as cell size and cell inclusion, but they differ from Type IV neurones in shape. The soma is oval or slightly elongated. The cell body contains several filamentous and oval mitochondria.

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입체퍼즐을 활용한 수학적 창의성 개발

  • 심상길;홍미경
    • 한국수학교육학회지시리즈E:수학교육논문집
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    • 제13권2호
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    • pp.765-773
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    • 2002
  • 정육면체 27개를 면끼리 붙여서 7개의 조각을 만들어, 이것을 조합하여 3${\times}$3${\times}$3 정육면체가 되도록 하는 퍼즐로 소마큐브(Soma Cube)가 많이 알려져 있다. 이런 입체퍼즐은 공간지각력과 문제해결능력을신장시켜서 창의력을 키우는 데 매우 효과적이므로, 교육적 소재로서 수업에 활용하면 좋다. 이 웍샵에서는 소마큐브와 같은 원리를 갖지만 조각의 모양이 전혀 다른 조이큐브(Joy Cube)와 펀큐브(Fun Cube, Diabolic Cube)를 직접 만들어서, 이를 수업에 활용하는 방법을 소개하려고 한다. 조이큐브는 초등학교 고학년, 펀큐브는 전학년에서 활용이 가능하다.

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Synthesis of Substituted Arylazothioxanthones as Potential Schistosomicidal Agents

  • El-Kerdawy, M.M.;El-Emam, A.A.;El-Subbagh, H.I.;Abushanab, E.
    • Archives of Pharmacal Research
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    • 제12권1호
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    • pp.5-7
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    • 1989
  • A series of 1-chloro-4-methyl-6-arylazo-9H-thioxanthen-9-ones were synthesized and schistosomicidal activity evaluated. It was found that, 1-chloro-4-methyl-6-(2-hydroxy-1-naphthylazo)-9H-thioxanthen-9-one possessed a promising activity against Schisto-soma mansoni in mice.

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서비스 기반 소프트웨어 개발을 지원하는 4D 프로세스 (A 4D Process for Service Oriented Software Development)

  • 박준석;문미경;남태우;염근혁
    • 한국정보과학회논문지:소프트웨어및응용
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    • 제35권11호
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    • pp.653-660
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    • 2008
  • 최근에 제시된 서비스 기반 컴퓨팅 패러다임에서의 서비스 기반 소프트웨어 개발을 지원하기 위한 체계적인 프로세스 모델에 대한 요구가 대두되고 있다. 기존에 제시된 Unified Software Development Process, UML Components 등의 방법론은 컴포넌트에 초점을 두고 만들어진 방법으로, 서비스의 정의, 바인딩, BPEL(Business Process Execution Language)을 이용한 서비스의 조합등과 같은 서비스 기반의 개발이 가지고 있는 특징을 반영하지 못하고 있다. 또한 서비스 기반의 개발 방법론으로 제시된 SOUP(Service Oriented Unified Process), SOMA(Service Oriented Modeling and Architecture) 등은 개념적인 절차가 위주로 되어 있지, 구체적인 가이드라인, 산출물 및 접근 방법을 명확히 제시하지 않는다. 그러므로 본 논문에서는 서비스 기반의 개발 패러다임을 지원하기 위한 체계화되고, 간소화된 프로세스 모델을 제시한다. 또한 OMG에서 제시한 SPEM(Software Process Engineering MetaModel)을 적용하여 프로세스 모델을 명시적으로 표현한다. 본 논문에서 제안된 프로세스 모델을 실제 서비스 기반의 개발에 적용함으로써 서비스 기반 소프트웨어 개발의 체계성 및 효율성을 증대시킬 수 있게 된다.

Investigation of nonlinear vibration behavior of the stepped nanobeam

  • Mustafa Oguz Nalbant;Suleyman Murat Bagdatli;Ayla Tekin
    • Advances in nano research
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    • 제15권3호
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    • pp.215-224
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    • 2023
  • Nonlinearity plays an important role in control systems and the application of design. For this reason, in addition to linear vibrations, nonlinear vibrations of the stepped nanobeam are also discussed in this manuscript. This study investigated the vibrations of stepped nanobeams according to Eringen's nonlocal elasticity theory. Eringen's nonlocal elasticity theory was used to capture the nanoscale effect. The nanoscale stepped Euler Bernoulli beam is considered. The equations of motion representing the motion of the beam are found by Hamilton's principle. The equations were subjected to nondimensionalization to make them independent of the dimensions and physical structure of the material. The equations of motion were found using the multi-time scale method, which is one of the approximate solution methods, perturbation methods. The first section of the series obtained from the perturbation solution represents a linear problem. The linear problem's natural frequencies are found for the simple-simple boundary condition. The second-order part of the perturbation solution is the nonlinear terms and is used as corrections to the linear problem. The system's amplitude and phase modulation equations are found in the results part of the problem. Nonlinear frequency-amplitude, and external frequency-amplitude relationships are discussed. The location of the step, the radius ratios of the steps, and the changes of the small-scale parameter of the theory were investigated and their effects on nonlinear vibrations under simple-simple boundary conditions were observed by making comparisons. The results are presented via tables and graphs. The current beam model can assist in designing and fabricating integrated such as nano-sensors and nano-actuators.