• 대한골관절종양학회지
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• 제19권1호
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• pp.37-41
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• 2013

고대 신경초종(ancient schwannoma)은 신경초종의 변이(variant)로서 천천히 자라나고 퇴행성 변화를 동반한 양성종양으로 알려져 있다. 또한 신경초종은 신전부에서는 상대적으로 드물게 발생하는 것으로 보고되어 왔다. 저자들은 50세 남자 환자의 상완 신전부 삼두근에서 발생한 고립성 고대 신경초종을 경험하였기에 이를 보고하고자 하였다.

• Journal of Korean Neurosurgical Society
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• 제30권9호
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• pp.1127-1129
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• 2001

The vast majority of schwannomas occur on cranial nerves, and rarely in the retroperitoneum. Solitary schwannoma in the psoas muscle is extremely rare. The authors present a case of retroperitoneal neoplasm in the psoas muscle identified as schwannoma which is not associated with von Recklinghausen's disease. A 68 years old female patient was admitted because of low back pain and weakness at the left leg. CT and MRI revealed a large cystic mass with well-defined margin and multiple internal septation within the left psoas muscle. The tumor was totally extirpated and histologically confirmed as a schwannoma.

• Journal of Korean Neurosurgical Society
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• 제30권sup1호
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• pp.140-143
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• 2001

We report a case of huge trigeminal schwannoma in a 10-year-old boy with neurofibromatosis type II, extending into the three spaces of the left middle, posterior, and infratemporal fossa. Initially we thought the child had a solitary trigeminal schwannoma, and most of the mass was resected successfully through one-stage operation, cranio-orbito-zygomatic intradural approach. However during the follow-up of the patient we found radiographically other multiple intracranial tumors of bilateral acoustic schwannomas, right trigeminal schwannoma, and foramen magnum tumor. Eventually the patient was diagnosed as neurofibromatosis type II presenting multiple intracranial tumors. We think childhood trigeminal schwannoma, even though in the case of solitary tumor, should be considered as possible initial manifestation of neurofibromatosis type II and that careful follow-up for the possibility of occurrence of other brain tumors such as schwannomas or meningiomas is necessary.

• 대한정형외과학회지
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• 제54권1호
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• pp.84-89
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• 2019

신경초종은 Schwann 세포에서 기원하는 양성 종양이다. 총상 신경초종은 총상형이나 다결정성의 성장 형태를 보이는 신경초종의 드문 아형이다. 총상 신경초종은 대부분은 피부와 피하조직에 고립성 병변(solitary lesion)을 보이지만 드물게 심부조직 내에 위치하기도 한다. 저자들은 매우 드물게 후경골 신경 및 원위부 분지 신경에서 발생하였으며, 심부조직에 위치하여 골 변형을 동반한 다발성 총상 신경초종이 재발한 1예를 경험하였기에 이를 보고하고자 한다.

• 대한골관절종양학회지
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• 제12권1호
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• pp.89-94
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• 2006

신경초종이 오래되어서 퇴행성 변화를 일으키면 이를 퇴행성 신경초종이라고 명칭하며, 드물게 보고되고 있다. 혈관주변의 초자화, 출혈, 석회화, 낭성 괴사, Antoni A 구역의 축소, 핵의 변형 등의 퇴행성 변화가 나타날 수 있으며, 이러한 퇴행성 변화로 인해 육종 등으로 잘못 진단되기 쉽다. 본원에서는 75세 남자 환자의 하퇴부에서 광범위한 출혈과 혈종, 낭성 변화, 석회화, Antoni A 구역의 축소 등의 퇴행성 변화가 진행된 퇴행성 신경초종을 경험하였기에 문헌적 고찰과 함께 이를 보고하는 바이다.

• 대한두경부종양학회지
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• 제23권2호
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• pp.192-194
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• 2007

Schwannoma, also named neurilemmoma, is a rare solitary and slow-growing tumor which originates from schwann cells of the nerve sheath. Schwannoma is a well-circumscribed, encapsulated masses that is attached to the nerve but can be separated from it. On microscopic examination, tumors show a mixture of two growth patterns, Antoni A and B. Surgical excision is the treatment of choice. Especially, Schwannoma of the tongue is very rare. We present a case of a 11-year-old child with a schwannoma of the tongue, measuring $1{\times}1cm$. During the operation the mass revealed itself as being encapsulated. The tumor was removed and diagnosed pathologically as a schwannoma.

• Journal of Yeungnam Medical Science
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• 제33권1호
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• pp.37-39
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• 2016

Schwannomas are uncommon neoplasms arising from Schwann cells of the neural sheath. Gastrointestinal schwannomas are rare, accounting for 1% of all malignant gastrointestinal tumors. Colonoscopic biopsy with immunohistochemical (IHC) staining is useful for confirming this tumor. We report on a patient with schwannoma arising from the ascending colon, which was detected by colonoscopy and endoscopic submucosal dissection was attempted. A 41-year-old man presented with abdominal discomfort. The patient was diagnosed with a subepithelial tumor on colonoscopy. He underwent endoscopic submucosal dissection. Histopathology and IHC staining confirmed that the colonic lesion was a benign schwannoma. However, the resection margin was positive. Therefore, laparoscopic ileocolectomy was performed.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제39권
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• pp.17.1-17.8
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• 2017

Background: Schwannomas (or neurilemmomas) of the tongue are benign, usually solitary, encapsulated masses derived from Schwann cells. Clinical evidence indicates that schwannoma is painless and slow growing. In general, schwannoma is treated by surgical excision. Here, we describe a case of schwannoma of the tongue, include a review of the literature from 1955 to 2016, and provide data on age, gender, location, presenting symptoms, size, and treatment methods. Case presentation: A 71-year-old female patient presented with a swelling at the base of the tongue of unknown duration. Magnetic resonance images (MRI) showed a large well-circumscribed solid mass and no significant lymph node enlargement. The mass was excised without removing overlying mucosa. Conclusions: The authors report a case of lingual schwannoma that was completely removed intraorally without preoperative biopsy. No sign or symptoms of recurrence were observed at 12 months postoperatively.

• Journal of Korean Neurosurgical Society
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• 제37권3호
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• pp.232-234
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• 2005

We report a rare case of a patient with meningeal solitary fibrous tumor. A 60-year-old woman presented with right leg monoparesis. Brain magnetic resonance imaging demonstrates a well enhancing huge mass, located in left parietal lobe. Cerebral angiography demonstrating increased vascularity in area of the tumor, which had feeder vessels extending from the internal carotid artery and external carotid artery. A presumptive diagnosis of meningioma or hemangiopericytoma was considered. At surgery, the consistency was firm and had destroyed the dura and skull. A gross total resection was performed. Immunohistochemically, tumor was strongly, and widely, positive for CD34 and vimentin. There was no staining for epithelial membrane antigen(EMA), S-100 protein, cytokeratin, and glial fibrillary acidic protein (GFAP). Differential diagnosis of intracranial solitary fibrous tumor includes fibroblastic meningioma, meningeal hemangiopericytoma, neurofibroma, and schwannoma.

• 대한세포병리학회지
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• 제10권1호
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• pp.55-60
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• 1999

Schwannoma is a benign encapsulated nerve sheath tumor and is histologically characterized by a mixture of Antoni type A and B tissue. A preoperative diagnosis of schwannoma by fine needle aspiration cytology or by any other means is important a preserve clinically important nerves. Therefore, it is necessary to make a specific cytological diagnosis of nerve sheath tumor. However, there are a few reports regarding cytological features of schwannoma in Korea. We experienced seven cases of solitary schwannoma and here we report their characteristic cytological features with a review of literatures. The characteristic features of schwannoma on cytology were the presence of both Antonl type A and B tissue. The cytologic findings common to all cases of schwannoma generally corresponded to the histologic findings of Antoni type A tissue, consisting of fragments of tightly cohesive fascicles with variable cellularity. Dense fibrillary substances were found, along with palisading nuclei and Verocay bodies. Individual tumor cells consisted of cohesive cells haying spindle or oval nuclei, with pointed ends and Indistinct cell borders. Variation in nuclear size and shape was also present. The Antoni type B consisted of scattered wavy or short spindle cells and some histiocytes and lymphocytes in the abundant myxoid background with formation of microcysts. Immunohistochemistry for S-100 protein revealed a uniformly strong positive reaction and was helpful to make more accurate diagnosis of schwannoma.