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The Development of Rule-based AI Engagement Model for Air-to-Air Combat Simulation (공대공 전투 모의를 위한 규칙기반 AI 교전 모델 개발)

  • Minseok, Lee;Jihyun, Oh;Cheonyoung, Kim;Jungho, Bae;Yongduk, Kim;Cheolkyu, Jee
    • Journal of the Korea Institute of Military Science and Technology
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    • v.25 no.6
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    • pp.637-647
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    • 2022
  • Since the concept of Manned-UnManned Teaming(MUM-T) and Unmanned Aircraft System(UAS) can efficiently respond to rapidly changing battle space, many studies are being conducted as key components of the mosaic warfare environment. In this paper, we propose a rule-based AI engagement model based on Basic Fighter Maneuver(BFM) capable of Within-Visual-Range(WVR) air-to-air combat and a simulation environment in which human pilots can participate. In order to develop a rule-based AI engagement model that can pilot a fighter with a 6-DOF dynamics model, tactical manuals and human pilot experience were configured as knowledge specifications and modeled as a behavior tree structure. Based on this, we improved the shortcomings of existing air combat models. The proposed model not only showed a 100 % winning rate in engagement with human pilots, but also visualized decision-making processes such as tactical situations and maneuvering behaviors in real time. We expect that the results of this research will serve as a basis for development of various AI-based engagement models and simulators for human pilot training and embedded software test platform for fighter.

Ustekinumab pharmacokinetics after subcutaneous administration in swine model

  • Grabowski, Tomasz;Burmanczuk, Artur;Derlacz, Rafal;Stefaniak, Tadeusz;Rzasa, Anna;Borkowski, Jacek
    • Journal of Veterinary Science
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    • v.22 no.5
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    • pp.47.1-47.10
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    • 2021
  • Background: Due to multiple similarities in the structure and physiology of human and pig skin, the pig model is extremely useful for biological drug testing after subcutaneous administration. Knowledge of the differences between subcutaneous injection sites could have a significant impact on the absorption phase and pharmacokinetic profiles of biological drugs. Objectives: This study aimed to analyze the impact of administration site on pharmacokinetics and selected biochemical and hematological parameters after a single subcutaneous administration of ustekinumab in pigs. Drug concentrations in blood plasma were analyzed by enzyme-linked immunosorbent assay. Pharmacokinetic analyses were performed based on raw data using Phoenix WinNonlin 8.1 software and ThothPro v 4.1. Methods: The study included 12 healthy, female, large white piglets. Each group received a single dose of ustekinumab given as a 1 mg/kg subcutaneous injection into the internal part of the inguinal fold or the external part of the inguinal fold. Results: The differences in absorption rate between the internal and external parts of the inguinal fold were not significant. However, the time of maximal concentration, clearance, area under the curve calculated between zero and mean residence time and mean residence time between groups were substantially different (p > 0.05). The relative bioavailability after administration of ustekinumab into the external part of the inguinal fold was 40.36% lower than after administration of ustekinumab into the internal part of the inguinal fold. Conclusions: Healthy breeding pigs are a relevant model to study the pharmacokinetic profile of subcutaneously administered ustekinumab.

Present Status and Future of AI-based Drug Discovery (신약개발에서의 AI 기술 활용 현황과 미래)

  • Jung, Myunghee;Kwon, Wonhyun
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.25 no.12
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    • pp.1797-1808
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    • 2021
  • Artificial intelligence is considered one of the core technologies leading the 4th industrial revolution. It is adopted in various fields bringing about a huge paradigm shift throughout our society. The field of biotechnology is no exception. It is undergoing innovative development by converging with other disciplines such as computers, electricity, electronics, and so on. In drug discovery and development, big data-based AI technology has a great potential of improving the efficiency and quality of drug development, rapidly advancing to overcome the limitations in the existing drug development process. AI technology is to be specialized and developed for the purpose including clinical efficacy and safety-related end points based on the multidisciplinary knowledge such as biology, chemistry, toxicology, pharmacokinetics, etc. In this paper, we review the current status of AI technology applied for drug discovery and consider its limitations and future direction.

Indigenous chicken production in Fiji Islands: knowledge, constraints and opportunities

  • Zindove, Titus Jairus;Bakare, Archibold Garikayi;Iji, Paul Ade
    • Animal Bioscience
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    • v.35 no.5
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    • pp.778-788
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    • 2022
  • Objective: The objective of the study was to understand and document socio-economic characteristics, production parameters, challenges and management practices used by Fijian households which keep indigenous chickens. Methods: A survey involving 200 households was carried out in coastal and inland communities of Fiji's wet and semi-dry ecoregions. Data on the influence of ecoregion and location of households relative to the sea on management practices, challenges and productivity of indigenous chickens were analyzed using logistic regression and general linear model of SAS software. Results: Irrespective of location relative to the sea and ecoregion, households indicated that they kept indigenous chickens for food and income generation. The Welsummer was the most (p>0.05) preferred breed. Households in the semi-dry inland communities had the largest (p<0.05) flocks compared to those in semi-dry coastal communities and the wet region. Chickens in the semi-dry region performed better (p<0.05) than those in the wet region in terms of number of clutches per year and mature live weight. Predators and feed shortages were the biggest challenges faced by households in all areas. The mongoose was ranked as the most (p>0.05) common predator followed by domestic dogs. Most households in the wet ecoregion's coastal communities housed their chickens at night, whereas communities in semi-dry ecoregion housed their chickens most of the time (p<0.05). In all regions, no households sold their chickens to commercial markets (p>0.05). Households in semi-dry ecoregion were more likely (p>0.05) to sell their chickens at the local market place. Conclusion: The productivity of local chickens in Fiji is low because of feed shortage, predators such as the mongoose and lack of market linkages.

A Case Study of the Curriculum of Data Science for Elementary School Teachers (초등교사 대상의 기초 데이터 과학 교육의 사례 연구)

  • Jo, Junghee
    • Journal of The Korean Association of Information Education
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    • v.25 no.6
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    • pp.899-906
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    • 2021
  • Data science is a discipline comprised of the academic fields of statistics, computer science, information technology, and domain knowledge. It analyzes data and derives meaningful results using complex technologies. Data science, along with artificial intelligence, is a core technology of the 4th industrial revolution; consequently, universities and companies worldwide are actively developing programs to develop data scientists who require high levels of expertise. In line with this undertaking, the field of elementary education has recognized the importance of data science education and so various studies have been conducted to develop curricula designed to help students understand how to use data. This paper proposes a curriculum for the purpose of educating elementary school teachers who are mostly non-majors in the computer field about data science. Satisfaction analysis was conducted based on questionnaires collected from students to analyze the effectiveness of the data science education proposed in this paper.

Effects of Neuromuscular Electrical Stimulation on Muscle Wasting with Cancer Patient: Study Protocol for a Systematic Review (신경근전기자극치료가 암환자의 근육 손실에 미치는 영향: 체계적 문헌고찰을 위한 프로토콜)

  • Eun Soo Park;Jong Hee Kim;Soo Dam Kim;Dong Hyun Kim;Min Seok Oh;Eun Jung Lee;Hwa Seung Yoo
    • Journal of Korean Medicine Rehabilitation
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    • v.33 no.2
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    • pp.49-55
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    • 2023
  • Objectives The purpose of this study is to analyze randomized controlled trials about neuromuscular electrical stimulation for muscle wasting with cancer patient and evaluate it's motor functionality effect. Methods Studies will be searched from 7 online databases (PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure [CNKI], Korean studies Information Service System [KISS], Research Information Sharing Service [RISS], Oriental Medicine Advanced Searching Integrated System [OASIS]). Participants will be cancer patients with muscle loss, regardless of cause, gender, race or age, interventions will be neuromuscular electrical stimulation. Other treatments than interventions will be the control group and the main outcome will be reviewed by motor functionality effect. Results Randomized controlled trials about neuromuscular electrical stimulation for muscle wasting should be included in the study. Primary outcomes include motor functionality effect. Secondary outcomes evaluate adverse event. The data uses Review Manager Software 5.4. Conclusions The conclusion of this study will provide a basis for determining whether neuromuscular electrical stimulation treatment for muscle wasting with cancer patient treatment is an effective and safe treatment method in clinical practice.

Panic Disorder Symptom Care System Based on Context Awareness (상황인식 기반의 공황장애 증상 관리 시스템)

  • Choi, Dong-Oun;Huan, Meng;Kang, Yun-Jeong
    • Journal of Korea Entertainment Industry Association
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    • v.13 no.4
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    • pp.63-70
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    • 2019
  • We extract the symptom of panic disorder from the context awareness environment. It extracts body context information through natural movement that exists in everyday life and uses a component of panic disorder. The ontology theory can be used to provide information on the degree of symptoms of panic disorder through inference process. For the components of panic disorder to the information processing based on ontology are defined as Classes. Panic disorder index is expressed through ontology modeling so that the condition of panic disorder can be known. The derivation of panic disorder component and panic disorder index will enable context awareness based information service for panic disorder. The context information is periodically synchronized with the context awareness on based device. Panic disorder can be used to improve the lifestyle of panic disorder.

Residual capacity assessment of post-damaged RC columns exposed to high strain rate loading

  • Abedini, Masoud;Zhang, Chunwei
    • Steel and Composite Structures
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    • v.45 no.3
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    • pp.389-408
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    • 2022
  • Residual capacity is defined as the load carrying capacity of an RC column after undergoing severe damage. Evaluation of residual capacity of RC columns is necessary to avoid damage initiation in RC structures. The central aspect of the current research is to propose an empirical formula to estimate the residual capacity of RC columns after undergoing severe damage. This formula facilitates decision making of whether a replacement or a repair of the damaged column is adequate for further use. Available literature mainly focused on the simulation of explosion loads by using simplified pressure time histories to develop residual capacity of RC columns and rarely simulated the actual explosive. Therefore, there is a gap in the literature concerning general relation between blast damage of columns with different explosive loading conditions for a reliable and quick evaluation of column behavior subjected to blast loading. In this paper, the Arbitrary Lagrangian Eulerian (ALE) technique is implemented to simulate high fidelity blast pressure propagations. LS-DYNA software is utilized to solve the finite element (FE) model. The FE model is validated against the practical blast tests, and outcomes are in good agreement with test results. Multivariate linear regression (MLR) method is utilized to derive an analytical formula. The analytical formula predicts the residual capacity of RC columns as functions of structural element parameters. Based on intensive numerical simulation data, it is found that column depth, longitudinal reinforcement ratio, concrete strength and column width have significant effects on the residual axial load carrying capacity of reinforced concrete column under blast loads. Increasing column depth and longitudinal reinforcement ratio that provides better confinement to concrete are very effective in the residual capacity of RC column subjected to blast loads. Data obtained with this study can broaden the knowledge of structural response to blast and improve FE models to simulate the blast performance of concrete structures.

Social Welfare Education and ICT(Information and Communication Technology) Utilization: Contents Analysis (사회복지교육과 ICT(Information and Communication Technology) 활용: 콘텐츠분석)

  • Jee-Sook Lee;Young Lim Lee
    • The Journal of the Convergence on Culture Technology
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    • v.9 no.1
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    • pp.669-678
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    • 2023
  • The aim of this study is to explore 'how is ICT being used in social work education and are they effective?' In order to answer the questions, a content analysis was conducted. Three academic databases, DBPIA, Kiss, EBSCO were searched to look for the articles that investigated ICT and social work education between Jan. 2016 and July, 2022. No study was found from DBPIA and Kiss. Based on inclusion criteria, thirteen articles were selected from EBSCO. Those articles were analyzed following 9 analytic themes: Country, Undergraduate or Graduate Student, Pedagogical Theory, Course Goal, Course Content, Evaluation Method, Outcome, Applied Software or Program. As results of the study, the platforms primarily used for social work education were VR, Second Life, PeopleSIM, course-tailored Applications. In addition, the following was illustrated as effectiveness of ICT in social work education; immersiveness, course satisfaction, improved knowledge, etc. Study limitations and recommendations of future applications were also discussed.

Diverse modeling techniques, parameters, and assumptions for nonlinear dynamic analysis of typical concrete bridges with different pier-to-deck connections: which to use and why

  • Morkos, B.N.;Farag, M.M.N.;Salem, S.;Mehanny, S.S.F.;Bakhoum, M.M.
    • Earthquakes and Structures
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    • v.22 no.3
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    • pp.245-261
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    • 2022
  • Key questions to researchers interested in nonlinear analysis of skeletal structures are whether the distributed plasticity approach - albeit computationally demanding - is more reliable than the concentrated plasticity to adequately capture the extent and severity of the inelastic response, and whether force-based formulation is more efficient than displacement-based formulation without compromising accuracy. The present research focusing on performance-based seismic response of mid-span concrete bridges provides a pilot holistic investigation opting for some hands-on answers. OpenSees software is considered adopting different modeling techniques, viz. distributed plasticity (through either displacement-based or force-based elements) and concentrated plasticity via beam-with-hinges elements. The pros and cons of each are discussed based on nonlinear pushover analysis results, and fragility curves generated for various performance levels relying on incremental dynamic analyses under real earthquake records. Among prime conclusions, distributed plasticity modeling albeit inherently not relying on prior knowledge of plastic hinge length still somewhat depends on such information to ensure accurate results. For instance, displacement-based and force-based approaches secure optimal accuracy when dividing, for the former, the member into sub-elements, and satisfying, for the latter, a distance between any two consecutive integration points, close to the expected plastic hinge length. On the other hand, using beam-with-hinges elements is computationally more efficient relative to the distributed plasticity, yet with acceptable accuracy provided the user has prior reasonable estimate of the anticipated plastic hinge length. Furthermore, when intrusive performance levels (viz. life safety or collapse) are of concern, concentrated plasticity via beam-with-hinges ensures conservative predicted capacity of investigated bridge systems.