• 제목/요약/키워드: Sodium effect

검색결과 2,745건 처리시간 0.054초

준비투약(準備投藥)으로서 Valium, Pentobarbital의 임상적(臨床的) 효과(效果)에 관(關)한 연구(硏究) (STUDIES ON THE CLINICAL EFFICACY OF VALIUM AND PENTOBARBITAL AS PREMEDICATING AGENT)

  • 김영진
    • 대한소아치과학회지
    • /
    • 제5권1호
    • /
    • pp.76-82
    • /
    • 1978
  • To evaluate clinically effect of Valium and Sodium pentobarbital as premedicating agent, both drugs and a placebo were compared in 45 patients (2 to 11 yrs). The results were as follows. 1. Both Sodium pentobarbital and Valium were superior to placebo for control of crying, cooperation and apprehension, but the statistically differences were not significant. 2. Both Valium and Sodium pentobarbital were superior to placebo for control of behavior in tense cooperative child; the differences were significant statistically. 3. The difference between Pentobarbital and Valium were-more pronounced at the initial level than at the subsequent readings, and Sodium pentobarbital was for superior at the initial level to the other drugs. 4. Paradoxical excitement occured in 2 cases on the Sodium pentobarbital group, and other apparent side effect did not occur, excluding mild drowsiness. 5. Neither Valium nor Sodium pentobarbital, as used in this study, resulted in consistantly better behavior in all patients.

  • PDF

Loxoprofen sodium 플라스타의 소염, 진통 작용 및 혈중 약물 농도에 대한 연구 (Anti-inflammatory and Analgesic Activities, and Plasma Concentration of Loxoprofen Sodium Plasters)

  • 채주병;전홍렬;이승목;정남주;김수균;조길도;김동연
    • Biomolecules & Therapeutics
    • /
    • 제7권2호
    • /
    • pp.198-203
    • /
    • 1999
  • Loxoprofen-Na (sodium 2-〔4-(2-oxocyclopentylmethyl)pheny)propionate dihydrate) is a potent analgesic drug. We developed loxoprofen-Na plasters to extend duration time of analgesic activity and to reduce side effect on gastrointestinal tract. Analgesic effect of Loxoprofen-Na plasters was investigated. Loxoprofen-Na plaster had good analgesic effect in rat paw pressure test, Tail-flick latency test and acetic acid-induced writhing test. Also, it had anti-inflammatory effect on carrageenan-induced rat hind paw edema. In pharmacokinetic study of Loxoprofen-Na, plasters dosage form showed that plasma drug concentration was prolonged up to 14 hours. So, we can conclude that loxoprofen-Na plasters, when applied on skin, will be a new type of drug for controlling the various local pain or inflammation.

  • PDF

Effect of Sodium Chloride on Biology of Catenaria anguillulae

  • Gupta, R.C.;Singh, K.P.
    • Mycobiology
    • /
    • 제30권4호
    • /
    • pp.219-224
    • /
    • 2002
  • Growth studies of Catenaria anguillulae isolates in response to sodium chloride indicated that all the isolates grew in linseed oil-cake agar medium containing sodium chloride up to 1.0%. Medium with 1.5% sodium chloride, however, completely checked the growth of all the isolates. The size of zoosporangia greatly increased with abundant zoospore production in medium containing sodium chloride at 0.5%.

포장 어묵의 수분활성 저하에 미치는 식품첨가제의 영향 2. 전분류, glycine, sodium lactate의 영향 및 어목의 수분활성예측법 (Effect of Food Humectant on Lowering Water Activity of Casing Kamaboko. 2. Effect of Lowering Water Activity of Starch, Glycine and Sodium Lactate and Prediction of the Water Activity Lowering Ability of Humectants)

  • 김동수;박영호
    • 한국수산과학회지
    • /
    • 제15권1호
    • /
    • pp.74-82
    • /
    • 1982
  • 포장 어묵을 제조할 때에 수분량을 일정하게 조정하여 각종 수분황성저하제를 첨가하였을 재 제품에 미치는 첨가제의 수분활성 저하 효과를 조사하기 위하여 전보(Kim and Park,1981)에 이어 전분류, glycine, sodium lactate의 영향을 살펴보았고 또한 실제 측정된 수분활성치와 Raoult의 식으로 계산한 예측치 및 Sloan and Labuza(l976)가 제안한직선경사법에 대하여 비교 검토하였다. 1. 옥수수, 감자, 고구마 및 소맥 전분은 다른 첨가물에 비하여 수분활성 저하 효과가 적었으며 가전분류의 효과는 거의 비슷하였다. 2. glycine 의 경우는 전분류에 비하여 상당히 좋은 효과를 나타내었으나 sodium lactate 보다는 떨어졌다. 3. sodium lactate의 수분활성 저하 효과는 상당히 우수하여 glycine의 3배 정도 효과가 있었으나 약간 짠맛이 있어 이를 완화하는 것이 문제가 된다고 생각된다. 4. 동일 첨가제에 있어서는 제품의 수분함량이 적은 경우가 수분활성 저하효과가 다소 나은 경향을 보였다. 5. Raoult의 식에 의하여 계산된 예측치는 식염과 sodium lactate의 경우를 제외하면 거의 실측치와 일치 되었다. 6. 본 실험에서 구한 각종 humectant의 회귀식은 수분활성 예측법으로 이용할 수 있다고 생각된다.

  • PDF

Effect of Sodium-Alternative Curing Salts on Physicochemical Properties during Salami Manufacture

  • Yim, Dong-Gyun;Shin, Dong-Jin;Jo, Cheorun;Nam, Ki-Chang
    • 한국축산식품학회지
    • /
    • 제40권6호
    • /
    • pp.946-956
    • /
    • 2020
  • To identify the effect of sodium-alternative curing salts on the quality properties of salami through the ripening process, four salami treatments were prepared with different curing salts, T1 (-control, NaCl 1.9%), T2 (+control, NaCl 1.9%+NaNO2 0.01%), T3 (KCl 1.9%+NaNO2 0.01%), and T4 (MgCl2 1.9%+NaNO2 0.01%), under 40 days ripening conditions. Sodium-alternative salts (T3 or T4) showed characteristically different quality traits compared with T2. Especially, T3 had lower pH, water activity, volatile basic nitrogen, and lipid oxidation after 20 days of ripening period, compare with T2 or T4 (p<0.05). Sodium nitrite had critical impact on increased a* values, and T3 showed higher a* values compared with T2 or T4 (p<0.05). Sodium nitrite reduced initial growth of coliforms but sodium-alternative salts did not affect microbial growth patterns. T2-T4 containing sodium nitrite had higher content of umami nucleotide flavor compounds compared with T1, regardless of the chlorine salt species. The combined use of sodium-alternative curing salts and minimal sodium nitrite was found to be an applicable strategy on development of low sodium salami without a trade-off of the product quality.

Effect of Sodium Butyrate on the Production of IDS by CHO-DG44 Cell

  • Jeon, Ok-Seon;Kang, Seon-Ah;Kim, Myoung-Hwa;Jeong, Yeon-Ho
    • 한국생물공학회:학술대회논문집
    • /
    • 한국생물공학회 2005년도 생물공학의 동향(XVI)
    • /
    • pp.214-217
    • /
    • 2005
  • 본 연구에서는 재조합 단백질 IDS의 생산성을 향상시키기 위한 방법으로 혈청이 첨가되거나 첨가되지 않은 배지에서 세포를 배양하는 동안 sodium butyrate를 첨가하였다. 두 배양 배지에서 모두 비록 세포 농도나 생존률이 감소되긴 했지만 생산성에서 상당히 높은 효과를 보였다.

  • PDF

저마직물의 펙티나제 정련 시 황산나트륨의 영향 (Effect of Sodium Sulfate on Ramie Fabrics Treated with Pectinase)

  • 박소영;송화순;김인영
    • 한국염색가공학회지
    • /
    • 제22권3호
    • /
    • pp.220-228
    • /
    • 2010
  • This study examines the scouring effect of pectinase on ramie fabric and influence of sodium sulfate as an activator for pectinase. The scouring effects were measured by the weight loss and pectin contents. SEM, weight loss, stiffness, moisture regain and dye ability of ramie fabric teated with pectinase/sodium sulfate were also measured. When ramie fabrics were desized with $\alpha$-amylase, the optimum conditions were pH 6.5 at $60^{\circ}C$ for 80 min with 1%(o.w.f) $\alpha$-amylase concentration. When ramie fabrics were scoured with pectinase, the optimum conditions were pH 8.5 at $55^{\circ}C$ for 30 min with 10%(o.w.f) pectinase concentration. Addition of sodium sulfate improved enzyme activity significantly, which increased proportionally with increasing sodium sulfate concentration. When 50 g/l of sodium sulfate was added, the surface became cleaner compared to the enzyme treatment without salt: weight and tensile loss, moisture regain and dyeability of the treated fabrics increased, while pectin contents and stiffness decreased. Therfore, sodium sulfate was effective activator for the pectinase treatment of flax fiber.

소수성 성질을 갖는 Poly(sodium acrylate)s의 물리적 특성 (Physical Characteristics of Hydrophobic Poly(sodium acrylate)s)

  • 안범수
    • 한국응용과학기술학회지
    • /
    • 제27권4호
    • /
    • pp.545-551
    • /
    • 2010
  • Hydrophobically monoendcapped poly(sodium acrylate)s formed hydrophobic microdomains in water. This was concluded on poly(sodium acrylate)s with a linear $C_{12}$-alkyl chain attached specifically at the end of the polymer. There was no well defined CMC (critical micelle concentration), but rather a gradual transition from a micelle free solution to a micelle solution. Steady state fluorescence spectroscopy indicates that the micro domains are rather hydrophobic. At pH 5 in the abscence of salt and at pH 9 in the prescence of 1 M sodium citrate the CAC (critical aggregation concentration) was in the range of 0.1 to 2.4 mM. However at pH 5 there was a linear increase in the transition concentration with a head-group size due to an increase in steric and electrostatic repulsions between polymer main chains. At pH 9 in the abscence of salt the transition concentration was in the range of 1 to 80 mM. For the larger polymers there was a effect which consisted of a concentration gradient of sodium counterion toward the hydrophobic domain. The effect was larger for the larger polymers because of the higher total sodium concentration and the less steep counterion concentration gradient.

특이산성토의 중화처리기법에 따른 생태적 녹화 (The Ecological Vegetation by the Neutralizing Treatment Techniques of the Acid Sulfate Soil)

  • 조성록;김재환
    • 한국환경복원기술학회지
    • /
    • 제22권1호
    • /
    • pp.47-59
    • /
    • 2019
  • This study was composed of four treatments [no treatment, phosphate + limestone layer treatment, phosphate + sodium bicarbonate + cement layer treatment, and phosphate + sodium bicarbonate + limestone layer treatment] for figuring out vegetation effects on the acid drainage slope. Treated acid neutralizing techniques were effective for neutralizing acidity and vegetative growth in order of [first: phosphate + sodium bicarbonate + limestone layer treatment, second: phosphate + sodium bicarbonate+cement layer treatment, third: phosphate + limestone layer treatment and fourth: no treatment] on the acid drainage slope. We found out that sodium bicarbonate treatment was additory effect on neutralizing acidity and increasing vegetaive growth besides phosphate and neutralizing layer treatments. In neutralizing layer treatments, Limestone layer was more effective for vegetation and acidity compared to cement layer treatment. Cement layer showed negative initial vegetative growth probably due to high soil hardness and toxicity in spite of acid neutralizing effect. Concerning plants growth characteristics, The surface coverage rates of herbaceous plants, namely as Lotus corniculatus var. japonicus and Coreopsis drummondii L were high in the phosphate + sodium bicarbonate + limestone layer treatment while Festuca arundinacea was high in the phosphate + sodium bicarbonate + cement layer treatment. We also figured out that soil acidity affected more on root than top vegetative growth.

아선약염색 면직물의 열발색 공정에 의한 발색효과 (Effect of Color Developing by Heat Treatment on Cotton Fabrics Dyed with Catechu Extract)

  • 이수정;장정대
    • 한국염색가공학회지
    • /
    • 제28권4호
    • /
    • pp.299-307
    • /
    • 2016
  • In order to clarify the availability of heat treatment for catechu dyeing, effect of color developing by heating process on cotton fabrics dyed with catechu extract was investigated. Dyed fabrics were heated various time(min) at $150^{\circ}C$. The cases of non-mordanting and mordanting were compared, and examined the effect of sodium acetate as an agent to promote the color developing to fabrics. Experiments with after-mordanting method showed that various colors can be obtained using catechu. K/S values of dyed fabrics with Al, Cu, Fe mordant were higher than the case of no mordant. The fabric by Cu mordanting showed 3 times to the case of no mordant. Fabrics dyed with catechu by mordanting lowered $L^*$ value while there was little change in $a^*$, $b^*$ value as the heating process progressed. Therefore, K/S values were increased due to heating process. The effects of adding sodium acetate in dyeing bath on dyed fabrics were shown higher K/S values, and the $L^*$ values were lower than those without sodium acetate according to heating time increase. The result show sodium acetate had a promoting effect on the color developing to the fabrics by heating process, it was very effective.