• Journal of Haehwa Medicine
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• v.16 no.1
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• pp.107-114
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• 2007

1. So-gal IS also called as so-jung, So-dan, Pe-so, Jung-so. Gyuk-so. 2. Cause of So-gal is impairment of Jin-Aek. induced by mal intake. stress, overstrain, intoxication, aging. The process is done by Cho-yeol. 3. Symptoms of So-gal is classified m to three categories Sang-So stands for polydipsia, Jung-So stands for polyphagia and weight loss, and Ha-So stands for polyuria. 4. In treating of So-gal, Chung-Hwa Bo-eum Bo-yang is the main principle. The fundamental basis of treating So-gal is Chi-shin. 5. It is not easy to perfectly classify symptoms of So-gal into three categories Therefore further inquiry is required on classification methods of So-gal.

• The Journal of Korean Medical History
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• v.18 no.2
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• pp.229-244
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• 2005

In order to find out how SoGal was perceived in the Korean medical history and under what logic it was treated, the SoGal section of UiBangYuChi and DongUiBoGam were compared and examined. Through this process, the following could concluded. First of all, in UiBangYuChi's SoGal Section, mainly the fire/heat theory was adopted. In DongUiBoGam's SoGal Section, the lack of Bodily Liquids and Blood theory was selected. Secondly, in DongUiBoGam's SoGal Section, it went beyond UiBangYuChi's perspective of viewing all thirst caused by fire/heat as SoGal, and perceived SoGal as a state of thirst reached for the lack of Bodily Liquids and Blood. Lastly, UiBangYuChi's SoGal Section accepts the fire/heat theory, and heavily restricts the use of BuJa in PalMi, while DongUiBoGam's SoGal Section elucidates the use of BuJa when needed.

• Journal of Sasang Constitutional Medicine
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• v.19 no.1
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• pp.1-18
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• 2007

1. Objectives This study is purposed to classify treatment and diagnosis of So-gal on the relationship of Sasang Constitutional Medicine. 2. Methods We compared conception, symptoms, mechanism and treatment of Sasangin's So-gal in ${\ulcorner}$Dongyisusebowon${\lrcorner}$ ${\ulcorner}$Gabobon${\lrcorner}$, ${\ulcorner}$Sinchukbon${\lrcorner}$ and ${\ulcorner}$Chobongwon${\lrcorner}$. 3. Result and Conclusion (1) So-gal of Soyangin is general disease, it is important disease of interior heat syndrome. So-gal of Taeumin is troubled by dryness of the lung, category of interior heat syndrome, but it bring about various complication. So-gal of Soeumin is important point that divide seriousness of disease. (2) So-gal is interior heat syndrome, it is related to interior heat syndrome of Soyangin, Taeumin. So-gal of Soeumin expresses conclusion of seriousness regardless of exterior and interior disease. (3) So-gal is related to nature, it is most important disease to Soyangin who is apt to variation of nature.

• Herbal Formula Science
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• v.10 no.2
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• pp.47-55
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• 2002

In Oriental medicine, So-gal(消渴) is similar to Diabetes Mellitus in the symptoms. In the medical treatment of So-gal(消渴), one kind of herb medicine is recorded in ancent medicine literatures. That herb medicine is a juice of vegetable drunken with herb medicine of So-gal(消渴). Milk(牛乳汁), human milk(人乳汁), gam-ja-jup(甘蔗汁), wo-jul-jup(藕節汁), li-jup(梨汁), sang-gang-jup(生薑汁) etc. is that. In that juices, Milk(牛乳汁), human milk(人乳汁), gam-ja-jup(甘蔗汁), wo-jul-jup(藕節汁), li-jup(梨汁) have sweety tastes, and cold nature. So they cure So-gal(消渴) come from dry and hot nature. Sang-gang-jup(生薑汁) is different with others in the taste and nature that sweety and hot taste and hot nature. Sang-gang-jup(生薑汁) cure the sequela of So-gal(消渴) by his hot nature. We think In Diabetes Mellitus, that juice can be used by drink for the treatment of diet because of simility between So-gal(消渴) and DM.

• The Journal of Korean Medical History
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• v.19 no.1
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• pp.149-166
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• 2006

Following former study(A Study of the Perception of SoGal in the early through mid Chosun Dynasty-Focusing on "UiBangYuChi(醫方類聚)" and "DongUiBoGam(東醫寶鑑)", there were medical attainments in this study on SoGal(消渴) of "UiRimChualYo(醫林撮要) SamSoMun(三消門)". 1. SoGal(消渴) theory of "UiRimChualYo(醫林撮要) SamSoMun(三消門)" presented the lack of Bodily Liquids and Blood theory(津液 血不足論) overcoming the limits of the fire/heat theory(火熱論). 2. In the "UiRimChualYo(醫林撮要) SamSoMun(三消門)", the concept of SoGal was started to change simple symptoms into the diseases including ethology, pathology and prognosis etc. 3. In the "UiRimChualYo(醫林撮要) SamSoMun(三消門)", the prescriptions of JaEum(滋陰) were thought significantly. On the other hand the prescriptions of HuaYul(火熱) were excluded at all. 4. The use of warm herb like BuJa(附子) was showed through GaGamSinGiHwan(加 減腎氣丸) and succeeded in "DongUiBoGam" the kidney's fire(坎火衰少論) lack theory. The futuristic percetion of "UiRimChualYo(醫林撮要) SamSoMun(三消門)" influenced "DongUiBoGam(東醫寶鑑)" was able to have progress ideas about SoGal.

• Journal of the Korean Professional Engineers Association
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• v.15 no.1
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• pp.14-23
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• 1982

1) The characteristic of the recipe for GAL-SOO is to make odorous, pharmaceutical cereal into plaster by honey-mixed boiling so as to be drunken whenever it needed. But the cereal which included sugar was boiled without adding sugar. 2) The part of cereal which was used mostly in making GAL-SOO was seeds of cereals. 3) The history of GAL-SOO was derived from GU GA PIL YONG, a document of WON dynasty of GHINA, but it was developped according to our taste in this county. 4) The pharmaceutical action of GAL-SOO was mainly to strengthen stomach, digestion and appeasing thirst. 5) GAL-SOO tastes so sour and sweet that it was splendid to drink especially in summer as a beverage. 6) The Value of developping GAL-SOO as a beverage is highly approved because of its expediency of recipe and tough endurance storing under ordinary temperature.

• Journal of the Korean Institute of Oriental Medical Informatics
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• v.11 no.1
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• pp.1-23
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• 2005

A symptoms of Diabetic is finded in many recordes, that is said to Diabetic or dryness or migratory arthralgia or flaccid paralysis of limb or abscess or arthralgia, but Diabetic is most closely symptom. So, study the 3-symptoms of Diabetes mellituscause, thses are polyuria and polyphasia and thirst, and this is similar symptoms of So-gal. So, bibliographic study or pathological approach of symptoms of So-gal, and So-gal in oriental medicine has come to the following conclution. The symptoms of So-gal is polyuria and polyphasia and thirst, is due to Simsinbulgyo, that is mean to breakdown of the normal physiological coordination between the heart and the kidney. A thirst is due to heat-transformation have an effect to the upper energizer and the heart and the lung and the stomach in Simsinbulgyo. A polyuria is due to failure of the kidneys Yang, that is due to failure of Yang of the heart in Simsinbulgyo.

• Journal of The Korean Astronomical Society
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• v.29 no.2
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• pp.119-136
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• 1996

To examine the effect of neighboring galaxies on the gravitational lensing statistics, we performed numerical simulations of lensing by many galaxies. The models consist of a galaxy in the rich cluster like Coma, or a galaxy surrounded by field galaxies in $\Omega_0 = 1$ universe with $\Omega_{gal} = 0.1,\;\Omega_{gal} = 0.3\;or\;\Omega_{gal}=1.0\;,\;where\;\Omega_{gal}$ is the total mass in galaxies. Field galaxies either have the same mass or follow Schechter luminosity function and luminosity-velocity relation. Each lensing galaxy is assumed to be singular isothermal sphere (SIS) with finite cutoff radius. In most simulations, the lensing is mainly due to the single galaxy. But in $\Omega_{gal} = 3$ universe, one out of five simulations have 'collective lensing' event in which more than two galaxies collectively produce multiple images. These cases cannot be incorporated into the simple 'standard' lensing statistics calculations. In cases where 'collective lensing' does not occur, distribution of image separation changes from delta function to bimodal distribution due to shear induced by the surrounding galaxies. The amount of spread in the distribution is from a few $\%\;up\;to\;50\%$ of the mean image separation in case when the galaxy is in the Coma-like cluster or when the galaxy is in the field with $\Omega_{gal} = 0.1\;or\;\Omega_{gal}=0.3.$ The mean of the image separation changes less than $5\%$ compared with a single lens case. Cross section for multiple image lensing turns out to be relatively insensitive to the presence of the neighboring galaxies, changing less than $5\%$ for Coma-like cluster and $\Omega_{gal}=0.1,\;0.3$ universe cases. So we conclude that Coma-like cluster or field galaxies whose total mass density $\Omega_{gal}<0.3$ do not significantly affect the probability of multiple image lensing if we exclude the 'collective lensing' cases. However, the distribution of the image separations can be significantly affected especially if the 'collective lensing' cases are included. Therefore, the effects of surrounding galaxies may not be negligible when statistics of lensing is used to deduce the cosmological informations.

• The Journal of Pediatrics of Korean Medicine
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• v.19 no.2
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• pp.229-241
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• 2005

Objective : This study was designed to investigate causes, symptoms and treatments for the diabetes insipidus with oriental medical literatures. Methods : We surveyed the oriental and western medical books from to recent published bocks that have articles on diabetes insipidus Results and Conclusions : The symptoms of diabetes insipidus are polyuria and polydipsia, these are similar symptoms of Pae-so(肺消), Gouk-so, So-gal(消渴), Sang-so(上消), Sin-so(腎消), So-sin(消腎), Ha-so(下消) and Sin-jung(腎中) of kinds of So-gal(消渴) in the oriental medicine. The major causes of diabetes insipidus are the deficiency of the yin of the kidney, the heat of the heart and the dryness of the pulmonary. The methods of treatment are tonifying the yin of the kidney(滋補腎陰), tonifying qi and arrest discharges(益氣固澁), removing heat to moisten dryness (淸熱潤燥) and promoting fluid production to quench thirst(生津止葛). The herbal-medications for treatment are So-galbang and Yidongtang(消渴方合二冬湯), Ryoumijihawangtang gamibang(六味地黃湯加味方).

• Proceedings of the Korean Society of Life Science Conference
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• 2002.12a
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• pp.13-19
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• 2002

To elucidate the regulatory mechanism for expression of sialyl-glycoconjugates and their biological functions, ninetheen sialyltransferase cDNAs including eleven by our group or co-works have been cloned and characterized so far. The cloned sialyltransferases are classified into four families according to the carbohydrate linkages they synthesize: ${\alpha}2,3-sialyltransferase$ (ST3Gal I-VI), ${\alpha}$ 2,6-sialyltransferase (ST6Gal I), GalNAc ${\alpha}$ 2,6-sialyltransferase (ST6GalNAc I-VI), and ${\alpha}2,8-sialyltransferase$ (ST8Sia I-VI). Each of the sialyltransferase genes is differentially expressed in a tissue-, cell type-, and stage-specific manner. These enzymes differ in their substrate specificity and various biochemical parameters. However, enzymatic analysis conducted in vitro with recombinant enzyme revealed that one linkage can be synthesized by multiple enzymes. We present here an overview of structure and function of sialyltransferases performed by our group and co-works. Genomic structures and transcriptional regulation of two kinds of human sialyltransferase gene are also presented.