• 대한치과의사협회지
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• 제49권4호
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• pp.219-226
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• 2011

Snoring and obstructive sleep apnea (OSA) are common sleep disordered breathing conditions. Habitual snoring is caused by a vibration of soft tissue of upper airway while breath in sleeping, and obstructive sleep apnea is caused by the repeated obstructions of airflow for a sleeping, specially airflow of pharynx. Researchers have shown that snoring is the most important symptom connected with the obstructive sleep apnea syndrome The treatment is directed toward improving the air flow by various surgical and nonsurgical methods. The current surgical procedures used are uvulopalatopharyngoplasty(UPPP), orthognathic surgery, nasal cavity surgery. Among the nonsurgical methods there are nasal continuous positive air pressure(CPAP), pharmacologic therapy. weight loss in obese patient, oral appliance(sleep splint). Sleep splint brings the mandible forward in order to increase upper airway volume and prevents total upper airway collapse during sleep. However, the precise mechanism of action is not yet completely understood, especially aerodynamic factor. The aim of this study evaluated the effect of conservative treatment of snoring and OSAS by sleep splint through measured aerodynamic change by an aerophone II. We measured a airflow, sound pressure level, duration, mean power from overall airflow by aerophone II mask. The results indicated that on a positive correlation between a decrease in maximum airflow rate and a decrease in maximum sound pressure level, on a negative correlation between a decrease in maximum airflow rate and a increase in duration.

• 한국콘텐츠학회논문지
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• 제14권1호
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• pp.326-336
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• 2014

본 연구는 한국인 성인을 대상으로 습관성 코골이와 대사증후군 구성 요소들과의 관련성에 대해 알아보고 또한 성별에 따른 차이점을 알아보고자 연구를 시행하였다. 2012년 3월부터 2012년 12월까지 일개 대학병원에 내원한 40세 이상 69세 이하까지 성인들 중 연구에 참여하기로 동의한 2,007명(남자 434명, 여자 1,573명)을 대상으로 하였다. 연구 대상자들에 대하여 구조화된 설문지를 작성하였고 신체 계측, 생활 습관 및 임상검사결과를 비교분석하였다. 연구 조사대상자들의 대사증후군의 유병률은 17.4% (남성 20.7%, 여성 16.5%)였으며, 연령이 증가할수록 대사증후군의 유병률도 같이 증가하였다. 연구 대상자에 대해 연령, 흡연, 음주, 수면시간, 규칙적 운동 변수를 보정한 후 다변량 로지스틱 회귀분석 결과 습관성 코골이에 의한 대사증후군의 위험이 여전히 유의하게 높았다(교차비: 1.96, 95% CI=1.45-2.66). 성별에 따라 연령, 음주, 흡연 요인을 보정한 후 다변량 로지스틱 회귀분석을 한 결과 여자에서 고밀도지질단백콜레스테롤, 혈당, 허리둘레의 발생 위험이 유의하게 높았으며(p<0.05), 대사증후군의 발생 위험도 유의하게 높았으나(교차비: 2.36, 95% CI= 1.64-3.40), 남자에서는 대사증후군 구성 요소 및 대사증후군 발생 위험이 높아지지 않았다.

• 대한임상검사과학회지
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• 제38권3호
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• pp.212-217
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• 2006

Obstructive sleep apena syndrome (OSAS) is accompanied by the following symptoms: apnea caused by upper respiratory tract obstruction while sleeping, repetitive lowering of $SpO_2$, severely affected excessive daytime sleepiness (EDS), suffocation/frequent awakeness while sleeping, daytime lethargy, and lack of concentration. OSAS was investigated with sex, age, body weight, body mass index (BMI), neck circumference and snoring sound as clinical characteristics and the anticipating factors of OSAS were studied in relation with the apnea-hypopnea index (AHI). The subjects were 42 people (male 34/female 8) who visited the clinic due to snoring and had polysomnography evaluation. AHI was differenciated into normal (less than 0~5/hr), mild (5~15/hr), moderate (15~30/hr) and severe (more than 30/hr). As the apnea-hypopnea index (AHI) gets higher, the snoring sound was louder (p<0.01), neck circumference was thicker (p<0.05) and also there were relative correlations with body weight (p<0.01), body mass index (p<0.05), snoring sound (p<0.01) and neck circumference (p<0.01). Since the snoring sound and neck circumference explained 32.8% of the AHI distribution, if the patient was severely snoring or had a thick neck circumference due to obesity, the apnea-hypopnea index showed a predisposition to the obstructive sleep apnea syndrome.

• Annals of Clinical Neurophysiology
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• 제17권2호
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• pp.61-67
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• 2015

Background: The aim of this study was to investigate the predictive value of snoring frequency in the diagnosis and severity of obstructive sleep apnea. Methods: Patients who underwent polysomnography with one or more of the following characteristics were included: 1) sleepiness, non-restorative sleep, fatigue, or insomnia symptoms; 2) arousal due to cessation of breathing or the occurrence of gasping or choking when waking up; and 3) habitual snoring, breathing interruptions, or both, noted by a bed partner or other observer. We analyzed the differences in clinical and polysomnographic variables between patients with and without obstructive sleep apnea and investigated the associations of those variables with obstructive sleep apnea severity. Results: One hundred ninety-three patients met the inclusion criteria, and 145 of the 193 patients were diagnosed with obstructive sleep apnea. Multiple logistic regression analysis showed that large neck circumference (p = 0.0054) and high snoring index (p = 0.0119) were independent predictors for obstructive sleep apnea. Moreover, between the obstructive sleep apnea severity groups, there was a strong tendency of difference in body mass index (p = 0.0441) and neck circumference (p = 0.0846). However, there was no significant difference in snoring frequency according to obstructive sleep apnea severity (p = 0.4914). Conclusions: We confirmed that snoring frequency is a predictor of obstructive sleep apnea. In addition, we showed for the first time that snoring frequency is not associated with obstructive sleep apnea severity, thus it is not a valuable marker for predicting obstructive sleep apnea severity.

• 수면정신생리
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• 제18권2호
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• pp.87-94
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• 2011

목 적 : 폐쇄성 수면무호흡증은 흔하고 심각한 질환이므로 적극적인 진단과 치료가 필요하다. 본 연구에서는 이미 증상이 있어 코골이 클리닉을 방문한 환자들의 코골이와 수면무호흡증에 대한 인식 정도를 조사하고자 하였다. 방 법 : 서울대학교병원 이비인후과 코골이 클리닉을 방문한 179명(남자 135명, 여자 44명)의 환자를 대상으로 설문 조사를 시행하였다. 설문지를 통해 클리닉을 방문한 이유, 수면무호흡증과 코골이 치료법, 검사 방법, 관련 증상 및 합병증에 대한 지식을 파악하였다. 결 과 : 환자들의 평균 연령은 $45.2{\pm}14.5$세였고 체질량지수의 평균값은 $24.8{\pm}3.4$였다. 환자들의 89.4%이 폐쇄성 수면무호흡증에 대해 들어보았다고 대답했으며, 주로 텔레비전과 라디오와 같은 대중매체(58.1%)를 통해 정보를 접했다고 했다. 코골이와 폐쇄성 수면무호흡증이 밀접한 관련이 있다는 것은 60.3%가 알고 있었고, 59.8%는 치료방침을 정하기 위해 야간 수면다원검사가 필요함을 알고 있었다. 코골이 치료 방법으로는 수술(67%)을 가장 많이 알고 있었다. 코골이 치료를 선택할 때 의사의 권고에 따르겠다는 사람들이 55.9%로 가장 많았으나 양압술을 선택한 사람은 아무도 없었다. 양압술 치료에 대해 들어본 사람들은 전체의 12.3%였고, 폐쇄성 수면무호흡증의 치료로 양압술을 선택한 사람은 아무도 없었다. 환자들 중에서 폐쇄성 수면무호흡증이 고혈압과 관련되어 있다는 것을 아는 사람들은 34.6%, 당뇨와 관련이 있다는 것을 아는 사람들은 12.8%였다. 결 론 : 이미 증상이 있어 코골이 클리닉을 방문한 사람들조차 폐쇄성 수면무호흡증의 위험성과 적절한 치료 방법에 대해 잘 알고 있지 못했다. 환자와 일반인들을 대상으로 폐쇄성 수면무호흡증에 대해 교육하고 홍보하는 것이 향후 질환의 진단율을 높이고 적절한 치료로 연결하며 연관 질환을 예방하는 것에 중요할 것이다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제18권3호
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• pp.463-469
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• 1996

Sonoring is caused by the repeated obstructions of versatile upper air way structure during sleep and is known as a kind of disease entity varing from simple snoring to obstructive sleep apnea syndrome(OSAS) which can cause serious cardiopulmonary complications due to its hypoxic pathophysiology. It has been reported that over 30% of middle-aged person have the problems of snoring and its accompanied symptomes and signs. Cephalometric measurements, frequently used to measure sella-nasion-subspinale(SNA) and sella-nasion-supramentale(SNB) angles, can provide the informations about the posterior airway space(PAS), the mandibular plane(MP) and the position of hyoid bone. These informations are useful in determining the therapeutic modalities of the snoring and OSAS patients. However, with conventional routine upright position, it does not represent the actual images of obstructive mechanism during sleep but only show the images of awaken normal upper airway anatomy. Therefore we have taken dual images of a routine upright lateral and a supine cephalometric view to compare both.

• 대한치과의사협회지
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• 제53권4호
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• pp.249-258
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• 2015

Snoring and obstructive sleep apnea are the representative sleep disordered breathings, caused by the temporary and repetitive constriction or obstruction of upper airway during sleep. They present with excessively vibratory noise and repetitive cease of respiration. These disorders commonly result in sleep disturbance and the subsequent daytime sleepiness, chronic fatigue. Furthermore, they can cause the serious and extensive complications including increased risk of hypertension, cardiac arrhythmia, cardiovascular disease, cerebrovascular accident, neurocognitive disturbance, traffic and occupational accidents, type II diabetes, childhood growth interruption, awakening headache and finally, relatively increased mortality rate. Because appropriate therapeutic intervention is best way for patients to relieve their symptoms and prevent their possible complications, it is very important for dentists to recognize their own role and responsibility in diagnosis and treatment of these disorders. For this, the present article provides the understanding of the clinical features, possible complications, various treatment modalities, and suitable treatment strategies for snoring and obstructive sleep apnea.

• 디지털융복합연구
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• 제15권10호
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• pp.307-314
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• 2017

본 연구에서는 하악전방이동 코골이 장치의 종류에 따라 최소한의 수직 교합량을 각각 다르게 확보하여 1급 교합을 가진 대상이 각 장치를 착용한 뒤, 수직 교합량이 하악의 위치, 근육의 변화, 혀의 위치등을 부가적으로 변화시켜 상기도의 면적에 영향을 주는 지 알아보고자 하였다. 수직량이 높을수록 상기도의 면적은 감소했으며, 혀의 위치를 후방으로 처지지 않게 할수록 상기도의 면적이 증가함을 알 수 있다. 코골이 감소를 위해 의사들은 환자들의 교합관계를 정확하게 진단하여 그 교합에 맞는 하악전방이동 코골이 장치를 선택해야 하고, 선택된 장치를 제작하는 치과 기공사 또한 장치의 효과를 높이기 위해 수직 교합량, 후방연 설정과 장치의 두께 등 디자인 설정을 고려해야 한다.

• 대한치과교정학회지
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• 제47권4호
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• pp.248-255
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• 2017

Objective: The purpose of this study was to investigate whether the craniofacial patterns of Korean children with snoring and adenotonsillar hypertrophy (ATH) could be categorized into characteristic clusters according to age. Methods: We enrolled 236 children with snoring and ATH (age range, 5-12 years) in this study. They were subdivided into four age groups: 5-6, 7-8, 9-10, and 11-12 years. Based on cephalometric analysis, the sagittal and vertical skeletal patterns of each individual were divided into Class I, II, and III, as well as the normodivergent, hypodivergent, and hyperdivergent patterns, respectively. Cluster analysis was performed using cephalometric principal components in addition to the age factor. Results: Three heterogeneous clusters of craniofacial patterns were obtained in relation to age: cluster 1 (41.9%) included patients aged 5-8 years with a skeletal Class I or mild Class II and hyperdivergent pattern; cluster 2 (45.3%) included patients aged 9-12 years with a Class II and hyperdivergent pattern; and cluster 3 (12.8%) included patients aged 7-8 years with a Class III and hyperdivergent pattern. Conclusions: This study found that the craniofacial patterns of Korean children with snoring and ATH could be categorized into three characteristic clusters according to age groups. Although no significantly dominant sagittal skeletal discrepancy was observed, hyperdivergent vertical discrepancy was consistently evident in all clusters.

• 대한한방소아과학회지
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• 제27권2호
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• pp.20-30
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• 2013

Objectives Sleep is closely related to children's and adolescent's growth. The purpose of this cross-sectional study is to examine the frequency of symptoms associated with sleep in childhood and adolescence and the impact in their growth. Methods This study had used questionnaire targeting 1001 children and adolescents. 532 of them were visited the Department of Pediatrics, the Oriental Medicine Hospital of ${\bigcirc}{\bigcirc}$University located in Dongdaemun-gu, Seoul, during the period between May and September in 2012. 469 of them were students in the lower grades at ${\bigcirc}{\bigcirc}$Elementary School located in Gangnam-gu, Seoul, during June, 2012. We used PASW Statistics 18.0 to analyze the relation between growth and symptoms associated with sleep by using Independent samples t-test, one-way ANOVA, and ANCOVA. Results As the result of this research, snoring(54.9%), sleep bruxism(34.2%), sleep talking(31.5%), sleep terror(17.1%) were most frequently seen as symptoms associated with sleep. Group of habitual snoring($p=0.008^{**}$) and sleep terror($p=0.016^*$) had lower height percentile than other groups. Groups with sleep talking($p=0.022^*$) had lower weight percentile than group without sleep talking. Groups with sleep talking($p=0.018^*$) or sleep walking($p=0.045^*$) had lower BMI percentile, and group with habitual sleep apnea($p=0.039^*$) had higher BMI percentile. Conclusions Symptoms during sleep such as snoring, sleep bruxism, sleep talking, and sleep terror occur frequently among children and adolescents. More importantly, snoring, sleep terror, and sleep talking may be associated with growth of children and adolescents.