• Journal of Advanced Marine Engineering and Technology
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• v.31 no.6
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• pp.707-714
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• 2007

The heat transfer coefficient and Pressure drop during gas cooling process of $CO_2$ (R-744) in inclined helical coil copper tubes were investigated experimentally. The main components of the refrigerant loop are a receiver. a variable-speed pump. a mass flow meter, a pre-heater and a inclined helical coil type gas cooler (test section). The test section consists of a smooth copper tube of 2.45mm inner diameter. The refrigerant mass fluxes were varied from 200 to $600[kg/m^2s]$ and the inlet Pressures of gas cooler were 7.5 to 10.0 [MPa]. The heat transfer coefficients of $CO_2$ in the inclined helical coil tubes increases with the increase of mass flux and gas cooling pressure of $CO_2$. The pressure drop of $CO_2$ in the gas cooler shows a relatively good agreement with those Predicted by Ito's correlation developed for single-phase in a helical coil tube. The local heat transfer coefficient of $CO_2$ agrees well with the correlation by Pitla et al. However, at the region near pseudo-critical temperature. the experiments indicate higher values than the Pitla et al. correlation. Therefore. various experiments in the inclined helical coil tubes have to be conducted and it is necessary to develop the reliable and accurate prediction determining the heat transfer and pressure drop of $CO_2$ in the inclined helical coil tubes.

• YAKHAK HOEJI
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• v.41 no.2
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• pp.247-254
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• 1997

The proteinase-activated receptor (PAR-2) belongs to the family of seven transmembrane region receptors, like the thrombin receptor, it is activated by specific proteolytic clea vage of its extracellular amino terminus and a synthetic peptide (SLIGRL). The earthworm protein fraction (EPF) extracted from Lumbricus rubellus elicted dose- and endothelium-dependent relaxations in phenylephrine-contracted rat thoracic aorta, whereas heat inactivated EPF (0.5 ${\mu}g$ /ml) had no effect. In the presence of the nitric oxide synthase inhibitor NG-methyl-L-arginine (1.8 micro M), EPF (0.5 ${\mu}g$ /ml)-induced relaxations were partially inhibited. Furthermore, EPF (0.5 ${\mu}g$ /ml) dramatically caused relaxation of thrombin-desenstized rat thoracic aorta. These results indicate that EPF activates PAR-2 in vascular endothelial cell. Intravenous injection of EPF (20 mg/kg, bolus) into anesthetized rats produced a marked depressor response. EPF (0 ~ 80 ${\mu}g$ /ml, gradient) was very effective on increasing of perfusion volume in rabbit ear vessel preparations. These results imply the usefulness of EPF as a vascular smooth muscle relaxant and indicate that the activation of PAR-2 may be a mechanism of EPF on hemokinetic improvement.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.12 no.2
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• pp.1-11
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• 2013

This research proposed integrated expressway traffic management strategy using ramp metering and toll mainline metering. This research suggested a traffic signal optimization model for integrated operation of ramp and mainline metering based on Demand-Capacity Model that is used to optimize allowable input volume for ramp metering in FREQ model. The objective function of this model is sectional throughput volume maximization, and this model can calculate optimal signal timings for mainline metering and ramp metering. This study conducted an effectiveness analysis of integrated metering strategy using PARAMICS and its API. It targeted Seoul's Outer Ring Expressway between Gimpo and Siheung toll gate. As a simulation result, integrated operation of mainline and ramp metering provided more smooth traffic flow, and throughput volume of mainline increased to 14% in congested section. In addition, a queue of 400 meter was formed at metering point of toll gate. This research checked that integrated traffic management strategy facilitates more efficient traffic operation of mainline and ramp from diffused traffic congestion.

• Journal of Arbitration Studies
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• v.15 no.3
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• pp.233-266
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• 2005

The world trading system has been under many changes in recent years. One notably important development is that much attention away from the multilateralism-oriented World Trade Organization towards FTA(Free Trade Agreement). The Free Trade Agreement signed between korea and chile formally have been come effective for free trade in goods and services as from April 1, 2004. During Free Trade Agreement negotiations between both countries. This study aims at presenting the suggestion for the Korea to make the WTO rules and FTA by analyzing The interpretation of FTA under WTO System. It was founded by the investigation of WTO rules, most of the provisions are similar with other FTA, but a little provisions different from other FTA's. It is an appearance from the contracting party's peculiar circumstances such as state of industrial development or future prospect, conditions around international trade. The whole world has entered the new stage of bilateral and multilateral FTA. The essential or new generation or bilateral and multilateral FTA is creating more trade opportunities, promoting all factors, commodity, service, capital, technology and talent freely flow through canceling the trade barriers between FTA, in order to develop together within the regions. It shows that the cooperations transfer form the whole region into FTA. FTA makes not only the free trade smooth ,but also takes place the trade distortion effect. especially as the agriculture has a speciality each country, should it is ignored in negotiation, many reactions will be occurred in the process of fta Therefore Korea needs to deliver the message that Korea's hub is an essential ingredient for an efficient FTA and WTO system in a bilateral and multilateral win-win framework. Consequently Korea should have criterions about the rules of FTA and WTO system for peculiar circumstances of Korean economy and international trade.

• Journal of Korean Medical classics
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• v.33 no.3
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• pp.135-156
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• 2020

Objectives : This paper aims to suggest an integrated explanation for the contrary reinforcing/reducing effects of Shaoyao. Methods : From a list of books on the history of herbology and Chinese Medicine as mentioned in the herbology textbook, main texts were selected for further examination, along with some books of the Four Masters of the Jin Yuan period and some general medical texts. These texts were thoroughly examined with keywords such as Shaoyao, Baishaoyao, Chishaoyao, Baishao, Chishao, out of which contents on reinforcing and reducing were selected and analyzed. Next, explanations of the mechanisms of the contrary effects that were found through categorization of the reinforcing and reducing effects were examined. Among the contrary effects, similarities were uncovered and further studied for deduction of an encompassing higher level mechanism. Results & Conclusions : Overall consideration of the contrary effects of Shaoyao revealed that its working mechanism is to collect qi in the yin-blood part through convergence to control qi among blood, to help smooth flow of blood, eliminate blood stagnation and reinforce blood production which in turn cools down heat.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.25 no.10
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• pp.1327-1336
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• 2001

The structural modes driven by the low wave-number components of smooth elastic wall pressure provide a relatively weak coupling between the flow and the wall motion. If the elastic thin plate has any resonant mode whose wave-number of resonance coincides with $\omega$/U$\sub$c/, the power will be transmitted to those modes of vibration by the flows. We examine the problem in which the elastic thin plate is subject to pressure fluctuations under turbulent boundary layer. Measurements are presented of the frequency spectra of the near- and far-field pressures and radiated sound contributed by the various wave modes of the thin elastic plate. Dispersion equation for wave motions of elastic plate is used to investigate the effect of bending waves of relatively low wave number on radiated sound. The low wave-number motion of elastic plate is observed to have much less influence on the low-frequency energy of wall pressure fluctuations than that of the rediated sound. High amplitude events of the wall pressure are observed to weakly couple with high-frequency energy of radiated sound for case of low tension applied to the plate. The sound source localization is applied to the measurement of radiated sound by using acoustic mirror system.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.28 no.1C
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• pp.47-55
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• 2003

This paper proposes a composition method of mosaic image from the compressed MPEG-2 video stream, in which the displacement between successive frames according to the camera operation is estimated directly from the information involved in the stream. In the proposed method. the approximated optical flow is constructed from motion vectors of macro blocks, and it is used to determine the parameters of the displacements according to the camera operation associated with pan and tilt. The extracted parameters are used to determine the geometric transform of successive video frames in order to construct a mosaic image. The construction of mosaic uses several blending techniques including the one proposed by Nichols in which an analytic weight is used to determine pixel values. Through the experiment, the blending technique based on analytic weights was superior to the others such as averaging and median-based techniques. It provided more smooth changes in background and made use of instantaneous frame information to construct a mosaic. The mosaic in the paper puts the emphasis on the reduction of computation because it is constructed from the motion vectors included in the compressed video without decoding and recalculating exact optical flows. The constructed mosaic can be used in the retrieval of the compressed video as the representative frame of a shot.

• International Journal of Fluid Machinery and Systems
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• v.2 no.4
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• pp.353-362
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• 2009

In the process of turbine modernizations, the investigation of the influences of water passage roughness on radial flow machine performance is crucial and validates the efficiency step up between reduced scale model and prototype. This study presents the specific losses per component of a Francis turbine, which are estimated by CFD simulation. Simulations are performed for different water passage surface roughness heights, which represents the equivalent sand grain roughness height. As a result, the boundary layer logarithmic velocity profile still exists for rough walls, but moves closer to the wall. Consequently, the wall friction depends not only on roughness height but also on its shape and distribution. The specific losses are determined by CFD numerical simulations for each component of the prototype, taking into account its own specific sand grain roughness height. The model efficiency step up between reduced scale model and prototype value is finally computed by the assessment of specific losses on prototype and by evaluating specific losses for a reduced scale model with smooth walls. Furthermore, surveys of rough walls of each component were performed during the geometry recovery on the prototype and comparisons are made with experimental data from the EPFL Laboratory for Hydraulic Machines reduced scale model measurements. This study underlines that if rough walls are considered, the CFD approach estimates well the local friction loss coefficient. It is clear that by considering sand grain roughness heights in CFD simulations, its forms a significant part of the global performance estimation. The availability of the efficiency field measurements provides an unique opportunity to assess the CFD method in view of a systematic approach for turbine modernization step up evaluation. Moreover, this paper states that CFD is a very promising tool for future evaluation of turbine performance transposition from the scale model to the prototype.

• Transactions of the Korean Society of Automotive Engineers
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• v.16 no.3
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• pp.30-37
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• 2008

The evaporation pressure drop of $CO_2$ (R-744) in horizontal tubes was investigated experimentally. The experiments were conducted without oil in a closed refrigerant loop which was driven by a magnetic gear pump. The main components of the refrigerant loop are a receiver, a variable-speed pump, a mass flow meter, a pre-heater and evaporator (test section). The test section consists of a smooth, horizontal stainless steel tube of 7.75 and 4.57 mm inner diameter. The experiments were conducted at saturation temperature of $-5^{\circ}C\;to\;5^{\circ}C$, and heat flux of 10 to $40kW/m^2$. The test results showed the evaporation pressure drop of $CO_2$ are highly dependent on the vapor quality, heat flux and saturation temperature. The pressure drop measured during the evaporation process of $CO_2$ increases with increased mass flux, and decreases as the saturation temperature increased. The evaporation pressure drop of $CO_2$ is very lower than that of R-22. In comparison with test results and existing correlations, the best fit of the present experimental data is obtained with the correlation of Choi et al. But existing correlations failed to predict the evaporation pressure drop of $CO_2$. Therefore, it is necessary to develop reliable and accurate predictions determining the evaporation pressure drop of $CO_2$ in a horizontal tube.

• The Korean Journal of Physiology and Pharmacology
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• v.24 no.4
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• pp.287-298
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• 2020

Ca²⁺ signaling of endothelial cells plays a critical role in controlling blood flow and pressure in small arteries and arterioles. As the impairment of endothelial function is closely associated with cardiovascular diseases (e.g., atherosclerosis, stroke, and hypertension), endothelial Ca²⁺ signaling mechanisms have received substantial attention. Increases in endothelial intracellular Ca²⁺ concentrations promote the synthesis and release of endothelial-derived hyperpolarizing factors (EDHFs, e.g., nitric oxide, prostacyclin, or K⁺ efflux) or directly result in endothelial-dependent hyperpolarization (EDH). These physiological alterations modulate vascular contractility and cause marked vasodilation in resistance arteries. Transient receptor potential (TRP) channels are nonselective cation channels that are present in the endothelium, vascular smooth muscle cells, or perivascular/sensory nerves. TRP channels are activated by diverse stimuli and are considered key biological apparatuses for the Ca²⁺ influx-dependent regulation of vasomotor reactivity in resistance arteries. Ca²⁺-permeable TRP channels, which are primarily found at spatially restricted microdomains in endothelial cells (e.g., myoendothelial projections), have a large unitary or binary conductance and contribute to EDHFs or EDH-induced vasodilation in concert with the activation of intermediate/small conductance Ca²⁺-sensitive K⁺ channels. It is likely that endothelial TRP channel dysfunction is related to the dysregulation of endothelial Ca²⁺ signaling and in turn gives rise to vascular-related diseases such as hypertension. Thus, investigations on the role of Ca²⁺ dynamics via TRP channels in endothelial cells are required to further comprehend how vascular tone or perfusion pressure are regulated in normal and pathophysiological conditions.