• Title/Summary/Keyword: Small-cell

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림프절의 전이성 소세포암종의 세침흡인 세포학적 소견 - 악성 림프종과의 감별을 중심으로 5예 분석 - (Fine Needle Aspiration Cytology of Metastatic Small Cell Carcinoma of Lymph Nodes - Comparison to Non-Hodgkin's Lymphoma on 5 Cases -)

  • 김연미;조혜제;고일향
    • 대한세포병리학회지
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    • 제7권1호
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    • pp.44-50
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    • 1996
  • Small cell carcinoma of the lung is characterized by cells with finely stippled chromatin and scanty cytoplasm as well as a particularly aggressive clinical course and favorable response to the chemotherapy. Recently percutaneous fine needle aspiration (FNA) biopsy has become both widely established and highly respected for the diagnosis of lung cancer. However metastatic small cell carcinoma of lymph node should be cytologically differentiated from the small round cell tumor of particular sites, especially malignant lymphoma, because small ceil carcinoma of classic oat cell type nay simulate small cell non-Hodgkin's lymphoma. We report five cases of metastatic small cell carcinoma of in-termediate cell type diagnosed by FNA of the enlarged lymph nodes of the neck and axilla. The cytologic smears contained diffuse small neoplastic cells larger than lymphocytes with dense, pyknotic nuclei and extremely scanty cytoplasm. Apparently viable large tumor cells have vesicular nuclei with granular, sometimes very coarse chromatin. The characteristic cytologic features of small cell carcinoma as compared to malignant lymphoma were as follows.: 1) small cells with dense pyknotic nuclei are evenly distributed in the background of apparently viable larger tumor cells, admixed with mature lymphocytes and phagocytic macrophages. 2) small loose aggregates of cells with nuclear melding are indicative of small cell carcinoma rather than non-Hodgkin's lymphoma. 3) the cytoplasmic and nuclear fragments of tumor necrosis are more dominant in the smears of small cell carcinoma. 4) nuclear membrane and nucleoli are generally indistinct in small cell carcinoma due to condensation of chromatin.

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기관지표면상피의 미세침윤성 편평세포암과 동반된 혼합성 소세포암종 -1례 보고- (Combined Small Cell Carcinoma Associated with Microinvasive Squamous Cell Carcinoma of Bronchial Surface Epithelium - A case report -)

  • 김윤정;심정원
    • Journal of Chest Surgery
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    • 제29권9호
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    • pp.1031-1035
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    • 1996
  • 폐의 편평상피암종에서 기관지표면상피의 화생에 대해서는 많은 이들에 의해서 밝혀진 바 있지만 그 외의 다른 종류의 폐암과 연관된 기관지 표면상피의 변화에 대해서는 그 예가 많지 않고 소세포폐암종에 대해서는 더욱 그러하다. 한편 소세포암종의 조직학적 분류와그아형에 대해서 지난수십년 간많은 관심이 모아져 왔다. 이 종량의 아형을분류하는기본적인 근거는 그 형태학적 판정 기준에 있다. 1967년 WHO폐암종 분류법이 제긍된 이후 3여러 기관에서 SCLC의 임상경과나 치료에 대한 반응, 그 아형을 연구하였다. 1988년 IASLC에서는 소세포암종을 그 형태학적 구분으로 세가지 아형 : Small cell carcinoma (2) Mixed small cel1/1arge ceil carcinoma (3) Combined small cell carcinoma로 분류하고 예후와 치료에 대한 반응의 차이에 대해서 언급하였다. 최근 저자들은 68세 남자환자에서 소세포암종에서 국소적으로 편평양분화를 보이는 세포가 함께 혼합되어 있는 주종괴와 분리되 어서 존재하는 기관지 상피세포에 편평상피암종이 동반된 예를 전폐 절제 술을 하고 조직 검사상 경험하였기에 문헌고찰과 함께 보고하는 바이다.

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5G 스몰셀 기술 및 활용 기술 동향 (Trends in 5G Small Cell and Application Technology)

  • 권동승;나지현
    • 전자통신동향분석
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    • 제37권2호
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    • pp.83-95
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    • 2022
  • 5G goes beyond people to serve indoor and outdoor companies and industries, as well as campuses such as halls, industrial complexes, educational institutions, stadiums, dense urban areas, rural areas, and government institutions. Therefore, a new approach to small cells is needed. Accordingly, 3GPP and Small Cell Forum are researching 5G small cell architecture; 3GPP, Small Cell Forum, and 5G Alliance for Connected Industries and Automation are also researching private networks tailored to meet the specific requirements of various companies and local governments. In particular, in the UK, a small cell-based technology is required for realizing the Joint Operator Technical Specifications-Neutral Host In-Building specification to cost-effectively secure indoor coverage. Further, the research on the SON(Self-Organizing Network) technology for small cells in 5G, where commercialization has begun, is required. The 5G-based small cell structure, private network, and Neutral Host In-Building and SON reviewed in this study are at the initial research stages; therefore, additional research is needed to secure the competitiveness of the small cell technology in 5G and Beyond 5G.

Analytical Study on Inter-Cell Handover via Non-Concentric Circles in Wireless Heterogeneous Small Cell Networks

  • Gu, Hangyu;Li, Shuangchun;Havyarimana, Vincent;Wang, Dong;Xiao, Zhu
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제12권5호
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    • pp.2029-2043
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    • 2018
  • In this paper, we propose a novel inter-cell handover approach from a new perspective in dense Heterogeneous and Small Cell Networks (HetSNets). We first devise a cell selection mechanism to choose a proper candidate small cell for the UEs that tend to implement inter-small cell handover (ICH). By exploiting the property of a typical non-concentric circle, i.e., circle of Apollonius, we then propose a novel analytical method for modeling inter-cell handover regions and present mathematical derivation to prove that the inter-small cell handover issues fit the property of the circle of Apollonius. We design an inter-cell handover algorithm (ICHA) by means of our proposed handover model to dynamically configure hysteresis margin and properly implement handover decision in terms of UE's mobility. Simulation results demonstrate that the proposed ICHA yields lower call drop rate and radio link failure rate than the conventional methods and hence achieve high Handover Performance Indicator (HPI).

이하선에 발생한 원발성 소세포암 1예 (A Case of Primary Small Cell Carcinoma of the Parotid Gland)

  • 고영범;박기철
    • 대한두경부종양학회지
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    • 제31권2호
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    • pp.36-38
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    • 2015
  • Small cell carcinoma is mainly found in the lungs and extrapulmonary origins of small cell carcinoma in GI tract, head and neck, genitourinary system consists only 4% of the tumor. Thus, small cell carcinoma of the parotid gland is an extremely rare disease. Extrapulmonary small cell carcinoma is characterized by an aggressive clinical course with early metastasis. We report a case of small cell carcinoma of parotid gland in a 82-year-old woman with painless neck mass, who was managed with radiation therapy after surgery and review of relevant literatures.

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식도의 소세포함 치험 1례 (Small Cell Carcinoma of the Esophayus)

  • 백효채
    • Journal of Chest Surgery
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    • 제27권12호
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    • pp.1056-1059
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    • 1994
  • Small cell carcinoma is a highly malignant esophageal tumor composed of anaplastic small cells with features very similar to those of its pulmonary counterpart. The prognosis is poorer than that of squamous carcinoma of the esophagus because of its propensity of generalized spread and metastasis. Once the diagnosis of small cell carcinoma was established, surgery should be undertaken as early as possible. We have described an experience of small cell carcinoma of the lower esophagus in a 72 year old male patient with a review of the literatures regarding treatment methods and prognosis.

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소세포폐암에저의 $^{18}F-FDG$ PET의 임상 이용 (Clinical Application of $^{18}F-FDG$ PET in Small Cell Lung Cancer)

  • 최준영
    • Nuclear Medicine and Molecular Imaging
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    • 제42권sup1호
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    • pp.29-31
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    • 2008
  • This review focuses on the clinical use of $^{18}F-FDG$ PET in small cell lung cancer. For initial staging of small cell lung cancer, $^{18}F-FDG$ PET appears to be better than conventional staging methods. $^{18}F-FDG$ PET seems to be potentially useful for detecting recurrence, restaging and therapy response assessment in small cell lung cancer. However, due to small number of literatures, the role of $^{18}F-FDG$ PET in small cell lung cancer requires further investigations.

방광의 소세포암종의 요 세포 소견 -1예 보고- (Voided Urine Cytology of Small Cell Carcinoma of the Urinary Bladder -A Case Report-)

  • 이원애;이승하
    • 대한세포병리학회지
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    • 제18권2호
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    • pp.153-156
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    • 2007
  • Primary small cell carcinoma of the urinary bladder is an extremely rare but important entity. We experienced a case of small cell carcinoma of the urinary bladder diagnosed by urine cytology. A 59-year-old man presented with gross hematuria and dysuria, and a calcified mass was detected at the left ureterovesical junction by cystoscopy. Abdominal ultrasonography revealed focal wall thickening at the left lateral side of the urinary bladder, and urine cytology findings were of an inflammatory background and atypical small round cells with minute hyperchromatic or pyknotic nuclei, scant cytoplasm, and rare nucleoli. In addition, atypical cells were scattered in an isolated single cell pattern or in small loose clusters with prominent nuclear molding. Subsequent histological and immunohistochemical examinations confirmed a diagnosis of small cell carcinoma.

Self-organized Spectrum Access in Small-cell Networks with Dynamic Loads

  • Wu, Ducheng;Wu, Qihui;Xu, Yuhua
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제10권5호
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    • pp.1976-1997
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    • 2016
  • This paper investigates the problem of co-tier interference mitigation for dynamic small- cell networks, in which the load of each small-cell varies with the number of active associated small-cell users (SUs). Due to the fact that most small-cell base stations (SBSs) are deployed in an ad-hoc manner, the problem of reducing co-tier interference caused by dynamic loads in a distributed fashion is quite challenging. First, we propose a new distributed channel allocation method for small-cells with dynamic loads and define a dynamic interference graph. Based on this approach, we formulate the problem as a dynamic interference graph game and prove that the game is a potential game and has at least one pure strategy Nash equilibrium (NE) point. Moreover, we show that the best pure strategy NE point minimizes the expectation of the aggregate dynamic co-tier interference in the small-cell network. A distributed dynamic learning algorithm is then designed to achieve NE of the game, in which each SBS is unaware of the probability distributions of its own and other SBSs' dynamic loads. Simulation results show that the proposed approach can mitigate dynamic co-tier interference effectively and significantly outperform random channel selection.

3GPP 소형셀 향상 표준화 기술 동향 (3GPP Standardization Activity for Small Cell Enhancement)

  • 백승권;장성철
    • 한국정보통신학회:학술대회논문집
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    • 한국정보통신학회 2014년도 추계학술대회
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    • pp.628-631
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    • 2014
  • 최근 다양한 형태의 스마트 기기 출현과 대중적 보급으로 인해 고속 데이터 전송에 대한 수요가 나날이 증가하고 있다. 이런 요구사항을 수용하기 위해 셀룰러 사업자 및 이동통신 장비 제조업체는 많은 새로운 기술에 대한 연구를 진행하였으며 이에 대한 결과로 향후 셀룰러 네트워크에서 성능 및 커버리지 향상을 위해 소형셀 기술을 하나의 중요한 요소 기술로 고려하고 있다. 셀룰러 네트워크에서 소형셀 기술은 데이터 요구량이 많은 위치에 소형셀을 밀집 배치하고 매크로 기지국 및 소형셀 기지국의 밀접한 협력을 통해 무선 네트워크의 용량을 증가시키는 것을 의미한다. 따라서 본 논문에서는 매크로 셀과 소형 셀이 다층으로 배치된 셀룰러 이동통신 구조를 제시하고 다층셀간의 협력을 통해 성능을 향상시킬 수 있는 다양한 요소기술들에 대해서 기술한다. 또, 이들 요소기술들을 바탕으로 최근 3GPP에서 활발히 논의되고 있는 LTE 소형셀 향상 표준화 동향에 대해 기술한다.

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