• Title/Summary/Keyword: Small animal

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Current status, challenges and prospects for pig production in Asia

  • Lu Wang;Defa Li
    • Animal Bioscience
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    • v.37 no.4_spc
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    • pp.742-754
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    • 2024
  • Asia is not only the primary region for global pig production but also the largest consumer of pork worldwide. Although the pig production in Asia has made great progress in the past, it still is confronted with numerous challenges. These challenges include: inadequate land and feed resources, a substantial number of small-scale pig farms, escalating pressure to ensure environmental conservation, control of devastating infectious diseases, as well as coping with high temperatures and high humidity. To solve these problems, important investments of human and financial capital are required to promote large-scale production systems, exploit alternative feed resources, implement precision feeding, and focus on preventive medicine and vaccines as alternatives to antibiotics, improve pig breeding, and increase manure recycling. Implementation of these techniques and management practices will facilitate development of more environmentally-friendly and economically sustainable pig production systems in Asia, ultimately providing consumers with healthy pork products around the world.

STATUS AND SCOPE OF SMALL RUMINANTS PRODUCTION IN DRY AREAS OF PAKISTAN - REVIEW -

  • Rafiq, M.
    • Asian-Australasian Journal of Animal Sciences
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    • v.8 no.3
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    • pp.205-212
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    • 1995
  • This paper describes small ruminant production systems in dry areas of Pakistan. Formal and informal surveys had identified that poor feed resources, as a result of harsh climatic conditions, is a major factor responsible for low sheep and goats production. In view of their recommendations, use of approaches like supplemental feeding and pasture production through an introduction of improved forage species in the country, are reviewed. The improvement in sheep production and associated socioeconomic benefits, are discussed.

Antibacterial activity of florfenicol composite nanogels against Staphylococcus aureus small colony variants

  • Liu, Jinhuan;Ju, Mujie;Wu, Yifei;Leng, Nannan;Algharib, Samah Attia;Luo, Wanhe
    • Journal of Veterinary Science
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    • v.23 no.5
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    • pp.78.1-78.13
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    • 2022
  • Background: Florfenicol might be ineffective for treating Staphylococcus aureus small colony variants (SCVs) mastitis. Objectives: In this study, florfenicol-loaded chitosan (CS)-sodium tripolyphosphate (TPP) composite nanogels were prepared to allow targeted delivery to SCV infected sites. Methods: The formulation screening, the characteristics, in vitro release, antibacterial activity, therapeutic efficacy, and biosafety of the florfenicol composite nanogels were studied. Results: The optimized formulation was obtained when the CS and TPP were 10 and 5 mg/mL, respectively. The encapsulation efficiency, loading capacity, size, polydispersity index, and zeta potential of the optimized florfenicol composite nanogels were 87.3% ± 2.7%, 5.8% ± 1.4%, 280.3 ± 1.5 nm, 0.15 ± 0.03, and 36.3 ± 1.4 mv, respectively. Optical and scanning electron microscopy showed that spherical particles with a relatively uniform distribution and drugs might be incorporated in cross-linked polymeric networks. The in vitro release study showed that the florfenicol composite nanogels exhibited a biphasic pattern with the sustained release of 72.2% ± 1.8% at 48 h in pH 5.5 phosphate-buffered saline. The minimal inhibitory concentrations of commercial florfenicol solution and florfenicol composite nanogels against SCVs were 1 and 0.25 ㎍/mL, respectively. The time-killing curves and live-dead bacterial staining showed that the florfenicol composite nanogels were concentration-dependent. Furthermore, the florfenicol composite nanogels displayed good therapeutic efficacy against SCVs mastitis. Biological safety studies showed that the florfenicol composite nanogels might be a biocompatible preparation because of their non-toxic effects on the renal tissue and liver. Conclusions: Florfenicol composite nanogels might improve the treatment of SCV infections.

A Least Squares Regression Model to Detect Quantitative Trait Loci with Polar Overdominance in a Cross of Outbred Breeds: Simulation

  • Kim, Jong-Joo;Dekkers, Jack C.M.
    • Asian-Australasian Journal of Animal Sciences
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    • v.26 no.11
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    • pp.1536-1544
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    • 2013
  • A least squares regression interval mapping model was derived to detect quantitative trait loci (QTL) with a unique mode of genomic imprinting, polar overdominance (POD), under a breed cross design model in outbred mammals. Tests to differentiate POD QTL from Mendelian, paternal or maternal expression QTL were also developed. To evaluate the power of the POD models and to determine the ability to differentiate POD from non-POD QTL, phenotypic data, marker data and a biallelic QTL were simulated on 512 F2 offspring. When tests for Mendelian versus parent-of-origin expression were performed, most POD QTL were classified as partially imprinted QTL. The application of the series of POD tests showed that more than 90% and 80% of medium and small POD QTL were declared as POD type. However, when breed-origin alleles were segregating in the grand parental breeds, the proportion of declared POD QTL decreased, which was more pronounced in a mating design with a small number of parents ($F_0$ and $F_1$). Non-POD QTL, i.e. with Mendelian or parent-of-origin expression (complete imprinting) inheritance, were well classified (>90%) as non-POD QTL, except for QTL with small effects and paternal or maternal expression in the design with a small number of parents, for which spurious POD QTL were declared.

Development of SiPM-based Small-animal PET

  • Lee, Jin Hyung;Lee, Seung-Jae;Chung, Yong Hyun
    • IEIE Transactions on Smart Processing and Computing
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    • v.4 no.5
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    • pp.324-329
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    • 2015
  • A decreased number of readout method is investigated to provide precise pixel information for small-animal positron emission tomography (PET). Small-animal PET consists of eight modules, and each module is composed of a $6{\times}6$ array of $2{\times}2{\times}20mm^3$ lutetium yttrium orthosilicate (LYSO) crystals optically coupled to a $4{\times}4$ array of $3{\times}3mm^2$ silicon photomultipliers (SiPMs). The number of readout channels is reduced by one-quarter that of the conventional method by applying a simplified row and column matrix algorithm. The performance of the PET system and detector module was evaluated with Geant4 Application for Emission Tomography (GATE) 6.1 and DETECT2000 simulations. In the results, all pixels of the $6{\times}6$ LYSO array were decoded well, and the spatial resolution and sensitivity, respectively, of the PET system were 1.75 mm and 4.6% (@ center of field of view, energy window: 350-650 keV).