• Natural Product Sciences
• /
• v.9 no.2
• /
• pp.64-67
• /
• 2003

The purgative activities of Whangryunhaedoktang (WT), Chunghyuldan (CD) and Rhei Rhizoma were measured to choose herbal formulae available for stroke patients suffering from constipation. When the laxative activity of Rhei Rhizoma and CD (the same dose as Rhei Rhizoma) compared, Rhei Rhizoma was more potent than CD. WT contained Gardeniae Fructus, which has been used as a laxative, as a ingredient. Nevertheless, WT did not show the purgative activity. WT and CD did not stimulate the transportation of small intestine. However, CD weakly stimulated the transportation of large intestine than Rhei Rhizoma. Accordingly, we believe that CD can be used as a useful purgative for stroke patients with constipation.

• Korean Journal of Veterinary Pathology
• /
• v.6 no.1
• /
• pp.7-9
• /
• 2002

Case 1 was showed severe caughing and nasal discharge, who was one of 5-month-old 18 male sheep taking inspection for MCF experiment. Pathological examination of case 1 was conducted. Macroscopic observations were the foamy sticky fluids in nasal and tracheal cavity, the grey spots with 2-4 mm diameter on the surface of lung. Histopathological observations were severe eosinophil and other round cell infiltration in general organs including lung, trachea, small intestine, large intestine, liver. Also, in the lung, there were parasite-cutting lesions in some alveolar spaces and bronchioles. Following these observations, case 1 was diagnosed as ovine lungworm infection.

• Journal of Trauma and Injury
• /
• v.32 no.1
• /
• pp.66-70
• /
• 2019

Traumatic diaphragmatic injuries (TDIs) are a rare complication in thoraco-abdominal trauma. The diagnosis is difficult and if left untreated, TDI can cause traumatic diaphragmatic hernia (TDH). Through an injured diaphragm, the liver, spleen, stomach, small intestine, and large intestine can be herniated to the thoracic cavity, but pancreatic herniation and pancreatitis are quite rare in TDH. This paper reports a case of pancreatitis developed by additional trauma in a patient with asymptomatic chronic TDH. A 58-year-old male visited the emergency department with a left abdominal injury after a fall 6 hours earlier. The vital signs were stable, but the amylase and lipase levels were elevated to 558 U/L and 1,664 U/L, respectively. Abdominal computed tomography (CT) revealed a left diaphragmatic hernia and an incarceration of the stomach, pancreatic ductal dilatation, and peripancreatic fatty infiltration. Additional history taking showed that he had suffered a fall approximately 20 years ago and had an accidentally diaphragmatic hernia through a chest CT 6 months earlier. A comparison with the previous CT revealed the pancreatitis to be caused by secondary pancreatic ductal obstruction due to the incarcerated stomach. For pancreatitis, gastrointestinal decompression was performed, and after 3 days, the pancreatic enzyme was normalized; hence, a thoracotomy was performed. A small ruptured diaphragm was found and reposition of the organs was performed. This paper reports the experience of successfully treating pancreatitis and pancreatic hernia developed after trauma without complications through a thoracotomy following gastrointestinal decompression.

• Journal of Veterinary Clinics
• /
• v.26 no.5
• /
• pp.504-507
• /
• 2009

An 1-year old male siberian tiger showing severe vomiting and blackish and frothy diarrhea for 3 days were dead in Seoul Zoo. Gross finding at necropsy were small amount of blood were found in abdominal cavity and intestine. In small and large intestine, there were necrosis and detachment epithelial cell of intestinal mucosa in histopathology. The presence of feline panleukopenia virus (FPV) antigen was detected by PCR. In microbiology, E.coli and Enterococcus faecalis were isolated from the stool. This case was diagnosed in death induced by FPV infection according to CBC, histopathology and PCR.

• Korean Journal of Veterinary Research
• /
• v.37 no.1
• /
• pp.167-176
• /
• 1997

The present investigation was focussed mainly on the development of the tumors and proliferating cells on the intestinal tracts of 1, 2-dimethyl-hydrazine(DMH)-treated young or adult rats. 26 rats(Wistar, 14 young rats weighting approximately 130~180gm and 12 adult rats weighting approximately 500~550gm) were given subcutaneously once weekly with 20mg of DMH/kg body weight(BW)/week for 8~22 weeks. Individual body weight were recorded weekly at the same day and time. The rats were killed at 8, 13, 15. 17, 19, 21 and 22 weeks. The intestinal tracts were opened longitudinally and carefully examined for tumors. The localization, number, and size of tumors were noted. Tumor-bearing areas were dissected out and fixed on neutral buffered 10% formalin and normal-looking mucosa from 8~22 weeks rats were also taken for fixation. Paraffin sections were stained by H-E for histopathological examination or with immunohistochemical stain for bromodeoxyuridine(Brdur) positive cells. 1. The growth proportion of body weight appeared to be decreased in the DMH-treated young rats than in control young rats and body weight of DMH-treated adult rats appeared to be 13.4% or less lower than weighted on 0 week. 2. Macroscopically, the developed tumors in the intestinal tracts were not observed as early as the 13 weeks after DMH treatment. The number of developed tumors per rat was found to be 14.3, 18.8, 22.3 in 15, 17 and 22 weeks. The numbers of tumors in intestinal regions per rat were 2.1, 4.3, 5.4, 2.5 in duodenum, jejunum, ilium and colon on 15 weeks, 2.3, 6.4, 7.8, 2.3, on 17 weeks, and 2.7, 9.3, 9.0, 1.3 on 22 weeks, respectively and the ileum and jejunum were higher in appearance rate of tumors and tumor types are dome shapes and diameter of largest tumor were 6.3mm. 3. Histopathologically, intestinal mucosa were thickened by the irregular distorted and distended crypts following hyperplasia. The tumors developed on the mucosa and submucosa and were recognized to be adenocarcinoma. 4. Immunohistochemically, the labeling index(LI) was calculated as the ratio of the number of Brdur-labeled cells to the total number of column cells of the crypts with longitudinal axis. LI of Brdur positive cells per crypt were 5.6%, 8.0% on small intestine of control and 22 week group, respectively and 3.7%, 12.7% on large intestine of control and 22 week group, respectively and were appeared to be increase in 22 week group than in control group and to be more number of proliferating cells in 22 week group than in control group. 5. LI of Brdur positive cells in 1, 2, 3, 4, 5 segments of crypt column were 11.7%, 10.7%, 3.8%, 0.6%, 0% in small intestine of control group and 23.5%, 11.8%, 2.3%, 2.4%, 0.8% in small intestine of 22 week group, and 5.4%, 7.4%, 3.8%, 1.0%, 0.4% in large intestine of control group and 29.5%, 20.3%, 5.9%, 6.3%, 1.3% in large intestine of 22 week group respectively. So results indicate that the number of proliferating cells by DMH treatment increase and were concentrated on the 1, 2 segments of crypt columns.

• Journal of Sasang Constitutional Medicine
• /
• v.9 no.2
• /
• pp.227-243
• /
• 1997

The experimental study used in this paper was done to examine the clinical effects of Taeumchowetang for the gastric ulcer and the function of gastrointestinal tract using rats and mice which were administered orally the water extraction from Taeumchowetang. Then, the counter-action of the water extraction on the isolated ileum and gastric fundus, the inhibitory effects of pylorus-ligated ulcer and indomethacin-induced ulcer, the associations with gastric juice secretion, total acidity, pepsin output, the transportability in the small and large intestine, were studied with administering acetylcholine chloride and barium chloride. In addition, it was investigated whether the central nervous system related to pain control and sleeping time was influenced by Taeumchowetang. The following results have been obtained; 1. As resulting from injection of acetylcholine chloride and barium chloride into the isolated ileum of rats and mice, Taeumchowetang led to have an inhibitory effect on the muscle contraction of the ileum. Then, acetylcholine chloride was measured as lower effect than barium chloride 2. For the inhibitory effect on contraction for the gastric fundus strip in rats by either acetylcholine chloride or barium chloride, the one showed low inhibitory effect, on the other hand the other showed density-dependent effect. 3. The water extraction was given on the pylorus ligated ulcer with using two different administration groups of 1,300mg/kg and 2,600mg/kg, each result was measured as 22.9% and 36.5% for an ulcerous inhibitory effect (p<0.05). 4. According to the two administration groups, the preventive effect was tabulated 18.1% and 29.3% for indomethacin-induced ulcer (p<0.05, P<0.01). 5. For associations with gastric juice secretion, total acidity, pepsin output in the administration group 2,600mg/kg, Taeumchowetang was recognized as having an inhibitory effects related to suppressive actions involving gastric juice secretion(p<0.05), and free acidity(p<0.01), but there was no significant association with total acidity and pepsin output. 6. To know the transportability in the intestine, BaSO4 solution was used. The transportability of the small intestine in the administration group 2,600mg/kg was 22.2% which was statistically significant compared with the large intestine's transportability(P<0.01). 7. In the administration group 1,300mg/kg and 2,600mg/kg, analgesic effect with against acetic acid was measured as being 16.8% and 24.4% which was shown as statistically siginificant(p<0.01). 8. No statistically significant association between Taeumchowetang and sleeping time was found in both 1,300mg/kg and 2,600mg/kg by administering phenobarbital-Na. According to the results of this study, Taeumchowetang has agreed with the effects of literature review. Further more in this study, Taeumchowetang also has preventive effects on pylorus-ligated ulcer. Hence, Teaumchowetang can be significant effect such as both anti ulcer agent and increasing gastric activity for the patients who suffer from gastric ulcer.

• Journal of Convergence for Information Technology
• /
• v.11 no.9
• /
• pp.173-181
• /
• 2021

The purpose of this study is to prove the existence of the meridians by analyzing the effect of bloodletting cupping on Back-Shu Points and venesection on sabonghyeul, which are treatments for gastrointestinal and circulatory diseases with Ryodoraku. We selected the charts of 30 patients who received the treatment such as bloodletting cupping on Back-Shu Points and venesection on sabonghyeul for gastrointestinal and circulatory diseases. First, the Ryodoraku test was conducted in a stable state. After taking a rest on the bed, he performed a venesection on sabonghyeul. And bloodletting cupping on Back-Shu Points was performed with prone position. After all the procedures were completed, Ryodoraku test was performed again. And the result was compared with previous test status. By bloodletting cupping on Back-Shu Points and venesection on sabonghyeul, the deviation between the current value of the right F5 (gallbladder)· H4 (small intestine)· H6 (large intestine) (p<.05, p<.05, p<.001), left H5 (triple energizer) (p<.05) and the average current of 24 source points was significantly decreased. The difference between the left and right currents at the site of F3 (kidney) showed a significant increase (p<.005). It can be proved the existence of meridians that Bloodletting cupping on Back-Shu Points and venesection on sabonghyeul showed significant changes in the F5 (gallbladder), H4 (small intestine), H6 (large intestine), F3 (kidney), H5 (triple energizer) in digestive and circulatory symptoms by Ryodoraku test.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.20 no.6
• /
• pp.1447-1450
• /
• 2006

To study on the assignment of the eight trigrams (八卦) in human body being based on based the number of HADO(河圖)-NAGSEO(洛書). Being based on the number of HADO(河圖)-NAGSEO(洛書) and the BEOK-HEE's diagram of eight trigrams order(伏羲次序圖), human being organ (five-Jang organs (liver, heart, spleen, lung and kidney), five organs (ear, eye, mouth and nose), provisional namely six entera for the process on intake, digestion, excretion of food (mouth, stomach, small intestine, large intestine, rectum, anus) are assigned eight trigrams (八卦). Eight trigrams(八卦) are attached to the based on the number HADO(河圖)-NAGSEO(洛書): 1-GEON(乾), 2-TAE(兌), 3-LEE(離), 4-JIN(震), 9-SON(巽), 6-GAM(坎), 7-GAN(艮), 8-GON(坤). And (八卦) are attached to the human being organs (five-Jang organs (live, heart, spleen, lung and kidney), five organs (ear, eye, mouth, nose, anus) : 1-GEON(乾)-left lung-left nose, 6-GAM(坎)-right kidney-right ear, 7-GAN(艮)-left heart-anus, 8-GON(坤)-right liver-right ear. Eight trigrams(八卦) are attached to the provisional namely six entera for the process on intake, digestion, excretion of food : the air(GEON 乾), the month(TAE 兌), the stomach(LEE 離), the small intestine(JIN 震), the large intestine(Son 巽), the rectum(GAM 坎), the anus(GAN 艮), the excrements(GON 坤). The BEOK-HEE's diagram of eight trigrams order(伏羲次序圖) means immutable order naturally. The process of the human being organs( five-Jang organs, five organs and six entera's digestion) is also unchangeable in region and program. Therefore we can set up the five-Jang organs, five organs and the process of six entera's digestion as the category of observation on the basis of BEOK-HEE's diagram of eight trigrams order(伏羲次序圖), and then we can arrange eight trigrams (八卦) on the five-Jang organs, five organs and the process of six entera's digestion.

• Asian-Australasian Journal of Animal Sciences
• /
• v.21 no.4
• /
• pp.603-615
• /
• 2008

Dietary fiber is an inevitable component in pig diets. In non-ruminants, it may influence many physiological processes in the gastrointestinal tract (GIT) such as transit time as well as nutrient digestion and absorption. Moreover, dietary fiber is also the main substrate of intestinal bacteria. The bacterial community structure is largely susceptible to changes in the fiber content of a pig's diet. Indeed, bacterial composition in the lower GIT will adapt to the supply of high levels of dietary fiber by increased growth of bacteria with cellulolytic, pectinolytic and hemicellulolytic activities such as Ruminococcus spp., Bacteroides spp. and Clostridium spp. Furthermore, there is growing evidence for growth promotion of beneficial bacteria, such as lactobacilli and bifidobacteria, by certain types of dietary fiber in the small intestine of pigs. Studies in rats have shown that both phosphorus (P) and calcium (Ca) play an important role in the fermentative activity and growth of the intestinal microbiota. This can be attributed to the significance of P for the bacterial cell metabolism and to the buffering functions of Ca-phosphate in intestinal digesta. Moreover, under P deficient conditions, ruminal NDF degradation as well as VFA and bacterial ATP production are reduced. Similar studies in pigs are scarce but there is some evidence that dietary fiber may influence the ileal and fecal P digestibility as well as P disappearance in the large intestine, probably due to microbial P requirement for fermentation. On the other hand, fermentation of dietary fiber may improve the availability of minerals such as P and Ca which can be subsequently absorbed and/or utilized by the microbiota of the pig's large intestine.

• Journal of Haehwa Medicine
• /
• v.13 no.1
• /
• pp.225-241
• /
• 2004

Objectives & Methods: We investigated 45 books to study etiology, pathology and acupuncture & Moxibustion treatment of diarrhea. Result and Conclusion 1. The pathogenic factors of diarrhea are external sensation(外邪感受), jungjishiljo(情志失調), weakness of the spleen and stomach(脾胃虛弱), improper diet(飮食不節), sinyanghueson(腎陽虧損), sueumyujang(水飮留腸), liver Gi invades the sp1een(肝氣乘脾), uhhyuljeche(瘀血阻滯). 2. The etiological cause of diarrhea are closely related to the malfunction of the spleen & stomach(脾胃) and the related jang and bu(臟腑)'s pathological alternation such as spleen & stomach(脾胃), large intestine(大腸), small intestine(小腸), liver(肝), sp1een(脾), and kidney(腎). 3. Acupuncture and moxibustion treatment application of diarrhea with the meridian system are in the following order from the most often mentioned meridian system to the least, urinary bladder meridian(膀胱經), spleen meridian(脾經), stomach meridian(胃經), conception channel meridian(任脈經), liver mehdian(肝經), governor channel meridian(督脈經), large intestine meridian(大腸經), lung meridian(肺經), triple-warmer meridian(三焦經), gall bladder meridian(膽經), Pericardium meridian(心包經). 4. Acupuncture and moxibustion treatment application of diarrhea with meridian point are in the following order from the most often mentioned meridian point to the least, Cheonchu(天樞) sixteen times, Sin-gwol(神厥) fifteen times, Joksamni(足三理), Gwanwon(關元) each twelve times, Daejangsu(大腸兪) eleven times, Taechung(太衝), Bisu(脾兪), Sojangsu(小腸兪) each ten times,Sinsu(腎兪) nine times, CC12(中脘) eight times, Samchosu(三焦兪), gokcheon(曲泉), Harweom(下廉) each seven times, Samgan(三間), Sameungyo(三陰交), Yisa(意舍), Jungnyo, Gyeungmun(京門) each six times, Gyeonggol(京骨), Jangmun(章門) each five times, Sangnyeom(上廉), Hapgok(合谷), Yangmun(梁門), Sanggu(商丘), Yanggang(陽綱), Hoeyang(會陽), Gihyeol(氣穴), Taegye(太谿), Gihae(氣海) each four times.