• 한국콘텐츠학회논문지
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• 제17권5호
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• pp.18-33
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• 2017

학교폭력의 연장선상에서 상시적으로 괴롭힘이 이루어지는 '사이버불링'이 심각한 사회적 문제로 대두되고 있다. 본 연구에서는 청소년 사이버불링에 관한 선행연구를 분석하여 사이버불링 가해행동에 미치는 개인, 가정, 또래, 학교, 사이버환경, 폭력경험 등과 관련된 변인들의 효과크기를 알아보았다. 국내학술논문 검색사이트(RISS)를 이용하여 2010년 1월 1일부터 2016년 10월 31일까지 학술지게제 논문 및 석 박사학위논문을 대상으로 '사이버불링', '사이버따돌림', '사이버폭력', '사이버괴롭힘', '온라인 및 SNS 또래괴롭힘' 이란 검색어로 선정된 총 43편의 논문을 대상으로 분석하였다. 그 결과 개인, 폭력경험 변인이 중간크기의 효과(0.28~0.29)를 나타냈고 또래, 가정, 사이버환경, 학교변수 순으로 작은 크기의 효과(0.08~0.13)를 나타냈다. 본 연구 결과는 청소년 사이버불링에 대한 교육적, 사회정책적 대응방안 마련과 직접적인 예방 및 개입을 위한 구체적 프로그램 개발의 기초자료로 활용될 것이다.

• 정보보호학회논문지
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• 제31권5호
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• pp.959-972
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• 2021

분산 신원증명은 정보주체가 자신의 신원정보를 직접 관리하고, 필요시 제공한다는 자기주권 신원증명의 개념을 기반으로 하고 있다. 하지만, 발급기관으로부터 신원정보를 발급받아 온다는 절차가 필요하고, 발급기관의 관리 소홀로 인한 대량의 정보 유출 우려가 존재한다. 본 논문에서는 정보주체와 발급기관을 일치시켜 1:1 또는 1:N 소규모 그룹에서 참여자들만 신원증명이 가능한 Peer DID 기술을 기반으로 개인 간 분산 신원증명 시스템을 제안한다. 블루투스와 같은 단거리 무선 통신을 이용하여 모바일 디바이스로 직접 연결하고, 정보주체가 직접 자신의 정보를 생성하여 상대방에게 제공하므로 정보의 자기주권을 실현한다. 제안 시스템을 통하여 신원증명 절차를 간소화하고, 보안 및 프라이버시를 개선할 수 있으며, 비용도 절감할 수 있다. 나아가 제안 시스템과 분산 원장을 연결하여 다른 도메인의 이용자와 상호 신원증명 할 수 있도록 확장된 구성도 가능하다. 향후에는 다양한 기술을 기반으로 사람과 사물, 사물과 사물 인증에도 활용할 수 있는 신원증명 시스템에 대한 확장 연구가 필요하다.

• Molecules and Cells
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• 제44권9호
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• pp.627-636
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• 2021

The three-dimensional organization of chromatin and its time-dependent changes greatly affect virtually every cellular function, especially DNA replication, genome maintenance, transcription regulation, and cell differentiation. Sequencing-based techniques such as ChIP-seq, ATAC-seq, and Hi-C provide abundant information on how genomic elements are coupled with regulatory proteins and functionally organized into hierarchical domains through their interactions. However, visualizing the time-dependent changes of such organization in individual cells remains challenging. Recent developments of CRISPR systems for site-specific fluorescent labeling of genomic loci have provided promising strategies for visualizing chromatin dynamics in live cells. However, there are several limiting factors, including background signals, off-target binding of CRISPR, and rapid photobleaching of the fluorophores, requiring a large number of target-bound CRISPR complexes to reliably distinguish the target-specific foci from the background. Various modifications have been engineered into the CRISPR system to enhance the signal-to-background ratio and signal longevity to detect target foci more reliably and efficiently, and to reduce the required target size. In this review, we comprehensively compare the performances of recently developed CRISPR designs for improved visualization of genomic loci in terms of the reliability of target detection, the ability to detect small repeat loci, and the allowed time of live tracking. Longer observation of genomic loci allows the detailed identification of the dynamic characteristics of chromatin. The diffusion properties of chromatin found in recent studies are reviewed, which provide suggestions for the underlying biological processes.

• Archives of Plastic Surgery
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• 제46권3호
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• pp.221-227
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• 2019

Background Gynecomastia is a common condition that can cause severe emotional and physical distress in both young and older men. Patients in whom symptomatic recalcitrant gynecomastia persists for a long time are potential candidates for surgery. Methods From January 2014 to January 2016, 15 patients underwent correction of gynecomastia through a single 3-mm incision at our institution. Only patients with true gynecomastia underwent surgery with this new technique. Through the small incision, sharp dissection was performed in a clockwise and counterclockwise direction describing two half-circles. Health-related quality of life and aesthetic outcomes were evaluated using a modified version of the Breast Evaluation Questionnaire (BEQ). Results The patients' average age was 23.5 years (range, 18-28 years), and their average body mass index was $23.2kg/m^2$ (range, $19.2-25.3kg/m^2$). One case was unilateral and 14 cases were bilateral. The weight of glandular tissue resected from each breast ranged from 80 to 170 g. No excess skin was excised. Bleeding was minimal. The mean operating time was 25 minutes (range, 21-40 minutes). No complications were recorded. All lesions were histologically benign. The patients' average score was 3.5 (on a 5-point Likert scale) in all domains of the BEQ for themselves and their partners. Conclusions In this study, we demonstrated the safety and reliability of a new technique that allows mastectomy through an imperceptible 3-mm incision. We obtained high patient satisfaction scores using our surgical technique, and patients reported considerable improvement in their social, physical, and psychological well-being after surgery.

• Bulletin of the Korean Chemical Society
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• 제22권2호
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• pp.213-218
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• 2001

Presented are the STM images of self-assembled monolayer of 2-mercaptoethanol on Au(111). Striped structures of ($6{\times}3_{\frac{1}{2}}$), ($5{\times}3_{\frac{1}{2}}$), ($4{\times}3_{\frac{1}{2}}$) and compact-($5{\times}3_{\frac{1}{2}}$) were observed after annealing at $80^{\circ}C.$ Analysis of the ordered structures revealed that the basic fundamental units of the ordered structures were three crystallographically non-equivalent ($3_{\frac{1}{2}}{\times}3_{\frac{1}{2}}$) $R30^{\circ}$ assemblies, and that the way of combination of the assemblies produced the four different structures. The($6{\times}3_{\frac{1}{2}}$) structure ( $\theta$ = 0.33) was composed of one ($3_{\frac{1}{2}}{\times}3_{\frac{1}{2}}$)$R30^{\circ}$ assembly, while the ($5{\times}3_{\frac{1}{2}}$) ( $\theta$ = 0.30) and ($4{\times}3_{\frac{1}{2}}$) ( $\theta$ = 0.38) structures were consisted of two ($3_{\frac{1}{2}}{\times}3_{\frac{1}{2}}$) $R30^{\circ}$ assemblies, separated by 5a and 4a, respectively. Furthermore, the compact-(5X 3½) structure ( $\theta$ = 0.50) was obtained by overlapping three ($3_{\frac{1}{2}}{\times}3_{\frac{1}{2}}$) $R30^{\circ}$ assemblies. In spite of the diversity in the adsorption structures, all the adsorption sites of 2-mercaptoethanol were fundamentally identical. On the other hand, the unannealed primitive SAM of 2-mercaptoethanol was characterized by two observations: a short-range order keeping the adsorbed molecules at approximately $3_{\frac{1}{2}}$ a and the small domains of the striped structures supporting that the observed surface structures on the annealed surface were the extension of the primitive layer of 2-mercaptoethanol. Comparing these observations with the already published structures of ethanthiol, it was concluded that the interaction between the hydroxyl groups of 2-mercaptoethanol might play a significant role in the adsorption step of 2-mercaptoethanol on Au(111) to organize the adsorption structures different from those of ethanthiol.

• 대기
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• 제31권1호
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• pp.17-28
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• 2021

We investigated the impact of domain size on the simulated summer precipitation over the Korean Peninsula using the Weather Research and Forecasting (WRF) model. Two different domains are integrated up to 72-hours from 29 June 2017 to 28 July 2017 when the Changma front is active. The domain sizes are adopted from previous RDAPS (Regional Data Assimilation and Prediction System) and current LDAPS (Local Data Assimilation and Prediction System) operated by the Korea Meteorological Administration, while other model configurations are fixed identically. We found that the larger domain size showed better prediction skills, especially in precipitation forecast performance. This performance improvement is particularly noticeable over the central region of the Korean Peninsula. Comparisons of physical aspects of each variable revealed that the inflow of moisture flux from the East China Sea was well reproduced in the experiment with a large model domain due to a more realistic North Pacific high compared to the small domain experiment. These results suggest that the North Pacific anticyclone could be an important factor for the precipitation forecast during the summer-time over the Korean Peninsula.

• Smart Structures and Systems
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• 제30권6호
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• pp.687-701
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• 2022

Inevitable response loss under complex operational conditions significantly affects the integrity and quality of measured data, leading the structural health monitoring (SHM) ineffective. To remedy the impact of data loss, a common way is to transfer the recorded response of available measure point to where the data loss occurred by establishing the response mapping from measured data. However, the current research has yet addressed the structural condition changes afterward and response mapping learning from a small sample. So, this paper proposes a novel data driven structural response reconstruction method based on a sophisticated designed generating adversarial network (UAGAN). Advanced deep learning techniques including U-shaped dense blocks, self-attention and a customized loss function are specialized and embedded in UAGAN to improve the universal and representative features extraction and generalized responses mapping establishment. In numerical validation, UAGAN efficiently and accurately captures the distinguished features of structural response from only 40 training samples of the intact structure. Besides, the established response mapping is universal, which effectively reconstructs responses of the structure suffered up to 10% random stiffness reduction or structural damage. In the experimental validation, UAGAN is trained with ambient response and applied to reconstruct response measured under earthquake. The reconstruction losses of response in the time and frequency domains reached 16% and 17%, that is better than the previous research, demonstrating the leading performance of the sophisticated designed network. In addition, the identified modal parameters from reconstructed and the corresponding true responses are highly consistent indicates that the proposed UAGAN is very potential to be applied to practical civil engineering.

• Journal of Veterinary Science
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• 제21권2호
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• pp.33.1-33.15
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• 2020

Bovine ephemeral fever virus (BEFV) causes bovine ephemeral fever, which can produce considerable economic damage to the cattle industry. However, there is limited experimental evidence regarding the underlying mechanisms of BEFV. Annexin A2 (AnxA2) is a calcium and lipid-conjugated protein that binds phospholipids and the cytoskeleton in a Ca²⁺-dependent manner, and it participates in various cellular functions, including vesicular trafficking, organization of membrane domains, and virus proliferation. The role of the AnxA2 gene during virus infection has not yet been reported. In this study, we observed that AnxA2 gene expression was up-regulated in BHK-21 cells infected with the virus. Additionally, overexpression of the AnxA2 gene promoted the release of mature virus particles, whereas BEFV replication was remarkably inhibited after reducing AnxA2 gene expression by using the small interfering RNA (siRNA). For viral proteins, overexpression of the Matrix (M) gene promotes the release of mature virus particles. Moreover, the AnxA2 protein interaction with the M protein of BEFV was confirmed by GST pull-down and co-immunoprecipitation assays. Experimental results indicate that the C-terminal domain (268-334 aa) of AxnA2 contributes to this interaction. An additional mechanistic study showed that AnxA2 protein interacts with M protein and mediates the localization of the M protein at the plasma membrane. Furthermore, the absence of the AnxA2-V domain could attenuate the effect of AnxA2 on BEFV replication. These findings can contribute to elucidating the regulation of BEFV replication and may have implications for antiviral strategy development.

• 반도체디스플레이기술학회지
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• 제22권3호
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• pp.112-118
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• 2023

As technology advances, the need for enhanced preparedness against cyber-attacks becomes an increasingly critical problem. Therefore, it is imperative to consider various circumstances and to prepare for cyber-attack strategic technology. This paper proposes a method to solve network security problems by applying reinforcement learning to cyber-security. In general, traditional static cyber-security methods have difficulty effectively responding to modern dynamic attack patterns. To address this, we implement cyber-attack scenarios such as 'Tiny Alpha' and 'Small Alpha' and evaluate the performance of various reinforcement learning methods using Network Attack Simulator, which is a cyber-attack simulation environment based on the gymnasium (formerly Open AI gym) interface. In addition, we experimented with different RL algorithms such as value-based methods (Q-Learning, Deep-Q-Network, and Double Deep-Q-Network) and policy-based methods (Actor-Critic). As a result, we observed that value-based methods with discrete action spaces consistently outperformed policy-based methods with continuous action spaces, demonstrating a performance difference ranging from a minimum of 20.9% to a maximum of 53.2%. This result shows that the scheme not only suggests opportunities for enhancing cybersecurity strategies, but also indicates potential applications in cyber-security education and system validation across a large number of domains such as military, government, and corporate sectors.

• 한국신재생에너지학회:학술대회논문집
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• 한국신재생에너지학회 2010년도 춘계학술대회 초록집
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• pp.95.1-95.1
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• 2010

Transparent conducting ZnO films were deposited to apply DSSC Substrate on glass substrates at $500^{\circ}C$ by ionbeam-assisted deposition. Crystallinity, microstructure, surface roughness, chemical composition, electrical and optical properties of the films were investigated as a function of deposition parameters such as ion energy, and substrate temperature. The microstructure of the polycrystalline ZnO films on the glass substrate were closely related to the oxygen ion energy, arrival ratio of oxygen to Zinc Ion bombarded on the growing surface. The main effect of energetic ion bombardment on the growing surface of the film may be divided into two categories; 1) the enhancement of adatom mobility at low energetic ion bombardment and 2) the surface damage by radiation damage at high energetic ion bombardment. The domain structure was obtained in the films deposited at 300 eV. With increasing the ion energy to 600 eV, the domain structure was changed into the grain structure. In case of the low energy ion bombardment of 300 eV, the microstructure of the film was changed from the grain structure to the domain structure with increasing arrival ratio. At the high energy ion bombardment of 600 eV, however, the only grain structure was observed. The electrical properties of the deposited films were significantly related to the change of microstructure. The films with the domain structure had larger carrier concentration and mobility than those with the grain structure, because the grain boundary scattering was reduced in the large size domains compared with the small size grains. The optical transmittance of ZnO films was dependent on a surface roughness. The ZnO films with small surface roughness, represented high transmittance in the visible range because of a decreased light surface scattering. By varying the ion energy and arrival ratio, the resistivity and optical transmittance of the films were varied from $1.1{\times}10^{-4}$ to $2.3{\times}10^{-2}{\Omega}cm$ and from 80 to 87%, respectively. The ZnO film deposited at 300 eV, and substrate temperature of $500^{\circ}C$ had the resistivity of $1.1{\times}10^{-4}{\Omega}cm$ and optical transmittance of 85% in visible range. As a result of experiments, we provides a suggestition that ZnO thin Films can be effectively used as the DSSC substrate Materials.