• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2014.10a
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• pp.628-631
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• 2014

Recently, the proliferation of new applications, e.g., mobile TV, Internet gaming, large file transfer, and the various of user terminals, e.g., smart phones and notebooks, has dramatically increased user traffic and network load. In order to meet this traffic growth, vendors and cellular operators are working on the development of new technologies and cellular standards. Within them, small cell deployment has been heralded as one of most promising way to increase both coverage and capacity of future cellular network. Small cell technology enables to improve capacity of cellular radio network by tight cooperation between small cell and macro cell in multi-tier network where small cells are densely deployed within macro cell coverage. In this paper, we describe the deployment scenarios for cooperation between macro cell and small cells and state-of-the-art technologies related to dense small cell deployment. Then, we also provide design principles and standardization trends for small cell enhancement in 3GPP.

• Journal of the Institute of Electronics and Information Engineers
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• v.53 no.5
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• pp.19-24
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• 2016

In Long Term Evolution-Advanced (LTE-A), small cell enhancement(SCE) has been developed as a cost-effective way of supporting exponentially increasing demand of wireless data services and satisfying the user quality of service(QoS). However, due to the dense and irregular distribution of a large number of small cells, the offloading scheme should be applied in the small cell network. In this paper, we propose an user offloading scheme for SCE in LTE-Advanced system. We divide the small cells into different clusters according to the reference signal received power(RSRP) from user equipment(UE). Within a cluster, We apply the user offloading scheme with the consideration of the number of users and interference conditions. Simulation results show that proposed scheme can improve the throughput, and spectral efficiency of small cell users. Eventually, proposed scheme can improve overall cell performance.

• Journal of the Institute of Electronics and Information Engineers
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• v.53 no.5
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• pp.13-18
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• 2016

In Long Term Evolution-Advanced (LTE-A), small cell enhancement(SCE) has been developed as a cost-effective way of supporting exponentially increasing demand of wireless data services and satisfying the user quality of service(QoS). However, there are many problems such as the transmission rate and transmission quality degradation due to the dense and irregular distribution of a large number of small cells. In this paper, we propose a clustering based interference management scheme in dense small cell network. We divide the small cells into different clusters according to the reference signal received power(RSRP) from user equipment(UE). Within a cluster, an almost blank subframe(ABS) is implemented to mitigate interference between the small cells. In addition, we apply the power control to reduce the interference between the clusters. Simulation results show that proposed scheme can improve Signal to Interference plus Noise Ratio(SINR), throughput, and spectral efficiency of small cell users. Eventually, proposed scheme can improve overall cell performance.

• Investigative Magnetic Resonance Imaging
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• v.23 no.4
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• pp.361-366
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• 2019

Desmoplastic small round cell tumor (DSRCT) is a rare and aggressive malignancy common in young male patient. Typical imaging features of DSRCT include multiple soft tissue masses in the peritoneal cavity, omentum, or mesentery without an organ of origin. This report presents a rare manifestation of DSRCT revealing a solitary large retroperitoneal mass with hepatic metastasis and malignant portal vein thrombosis in 70-year-old women together with the review of literature. The tumor showed a hemorrhagic and necrotic mass with peripheral portion of T2 hypo-intensity and delayed enhancement that indicated desmoplastic stroma with dense cellularity.

• Journal of Acupuncture Research
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• v.30 no.1
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• pp.57-70
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• 2013

This study was to investigated the effects of the bee venom on inhibition of cell growth via upregulation of death receptor expression in the A549 human lung cancer cells. Bee venom(1-5 ${\mu}g$/ml) inhibited the growth of A549 lung cancer cells by the induction of apoptotic cell death in a dose dependent manner. Consistent with apoptotic cell death, expression of TNFR1, Fas, death receptors(DR) 3, 4 and 6 was increased in the cells. Expression of DR downstream pro-apoptotic proteins including caspase-3, -9 and Bax was concomitantly increased, but the expression of Bcl-2, NF-${\kappa}B$ were inhibited by treatment with bee venom in A549 cells. Moreover, deletion of DR3, DR4 by small interfering RNA significantly reversed bee venom-induced cell growth inhibitory effect, whereas Apo3L strengthened anti-proliferative effect of bee venom through enhancement of DR3 expression. These results suggest that bee venom should exert anti-tumor effect through induction of apoptotic cell death in lung cancer cells via enhancement of death receptor expression, and that bee venom could be a promising agent for preventing and treating lung cancer.

• 한국태양에너지학회:학술대회논문집
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• 2009.04a
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• pp.220-224
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• 2009

The effect of addition of single and binary additives on the performance of dye-sensitized $TiO_2$ solar cells based on 1,2-dimethyl-3-propylimidazolium iodide (DMPII) in ethylene carbonate (EC) and gamma-butyrolactone (GBL) has been evaluated at different cell temperatures in the $30-120^{\circ}C$ range. The electrolyte containing a single additive, 2-(dimethylamino)-pyridine (DMAP) showed best performance, which showed further enhancement for an electrolyte containing binary additives, DMAP and 5-chloro-1-ethyl-2-methylimidazole (CEMI) in equal molar ratio. The performance of the dye sensitized solar cell (DSC) based on electrolyte containing binary additives were found to be better than an acetonitrile based electrolyte. The dependence of different photovoltaic parameters (Voc, Jsc, ff, n) of the DSC upon temperature has been studied over the $30-120^{\circ}C$ range and only a small decrease in conversion efficiency has been observed. Thus the electrolyte containing binary additives (DMAP, CEMI) in EC/GBL solvent and show better performance in the investigated temperature range ($30-120^{\circ}C$).

• Bulletin of the Korean Chemical Society
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• v.35 no.12
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• pp.3623-3626
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• 2014

Nuclear factor-erythroid 2-related factor 2 (Nrf2) regulates the expression of over 200 genes of antioxidant and phase II drug-metabolizing enzymes, and is highly expressed in non-small cell lung cancer (NSCLC). Nine derivatives of 4-(2-cyclohexylethoxy)aniline were designed. Our previous study demonstrated that IM3829 increases radiosensitivity of several lung cancer cells in vitro and in vivo. Here, biological effects of IM3829 derivatives (2a-2i) were evaluated. Compound 2g derivative effectively inhibits mRNA and protein expression of Nrf2 and HO-1. In addition, we observed over two fold enhancement in IR-induced cell death, from $2.90{\pm}0.22$ to $6.02{\pm}0.87$, in H1299 cancer cell-line. Among the nine derivatives, compound 2g derivative exhibited the highest enhancement of radiosensitizing effect via inhibition of Nrf2 activity.

• The Korean Journal of Physiology and Pharmacology
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• v.24 no.5
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• pp.413-422
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• 2020

Delphinidin is a major anthocyanidin compound found in various vegetables and fruits. It has anti-oxidant, anti-inflammatory, and various other biological activities. In this study we demonstrated the anti-cancer activity of delphinidin, which was related to autophagy, in radiation-exposed non-small cell lung cancer (NSCLC). Radiosensitising effects were assessed in vitro by treating cells with a subcytotoxic dose of delphinidin (5 μM) before exposure to γ-ionising radiation (IR). We found that treatment with delphinidin or IR induced NSCLC cell death in vitro; however the combination of delphinidin pre-treatment and IR was more effective than either agent alone, yielding a radiation enhancement ratio of 1.54 at the 50% lethal dose. Moreover, combined treatment with delphinidin and IR, enhanced apoptotic cell death, suppressed the mTOR pathway, and activated the JNK/MAPK pathway. Delphinidin inhibited the phosphorylation of PI3K, AKT, and mTOR, and increased the expression of autophagy-induced cell death associated-protein in radiation-exposed NSCLC cells. In addition, JNK phosphorylation was upregulated by delphinidin pre-treatment in radiation-exposed NSCLC cells. Collectively, these results show that delphinidin acts as a radiation-sensitizing agent through autophagy induction and JNK/MAPK pathway activation, thus enhancing apoptotic cell death in NSCLC cells.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.37A no.12
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• pp.1093-1105
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• 2012

We propose an interference space reuse (ISR) algorithm for the MU-MIMO design in 3-cell downlink interference channels. Also, we provide a strategy for the adoption of the ISR scheme in the cellular network. In the multicell interference channels, the cell edge users may undergo severe interferences and their signals should be protected from the interferers for reliable transmissions. However, the intra cell users do not only experience small interferences but also they require small transmission power for stable communication. We provide a vector design algorithm based on ISR, where intra cell users are served through reusing the cell edge users' interference space. The performance enhancement reaches 20% compared to the fractional frequency reuse (FFR) scheme combined with IA through the scheduling between the cell edge users and the intra cell users. Also, it can be used to enhance the cell edge throughput when the quality of service (QoS) requirements of the intra cell users are fixed.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.22 no.1
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• pp.183-189
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• 2018

This paper proposes distributed file placement and coverage expansion techniques for mitigating the traffic bottleneck in backhaul for small-cell networks. In order to minimize the backhaul load with limited memory space, the proposed scheme controls the coverage and file placement of base station according to file popularity distribution and memory space of base stations. In other words, since the cache hit ratio is low when there is small memory capacity or widespread file popularity distribution, the base stations expand its coverage and cache different set of files for the user located in overlapped area to exploit multiple cached file sets of base stations. Our simulation results show that the proposed scheme outperforms the conventional cache strategy in terms of network throughput when there is small memory capacity or widespread file popularity distribution.