• Title/Summary/Keyword: Small Cell

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A Case of a Small Cell Carcinoma of the Pleura (흉막에 발생한 소세포암 1예)

  • Choi, Chang-Min;Um, Sang-Won;Yoo, Chul-Gyu;Lee, Choon-Taek;Kim, Young-Whan;Han, Sung-Koo;Shim, Young-Soo
    • Tuberculosis and Respiratory Diseases
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    • v.53 no.1
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    • pp.52-55
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    • 2002
  • A extrapulmonary small cell carcinoma is a very rare disease, and a primary pleural manifestation is extremely rare. A diagnosis of a small cell carcinoma should be based on the cell morphology, histological pattern, and an immunohistochemical study. We recently experienced a case of small cell carcinoma (SCC) of the pleura in a 59-year-old man who had suffered from right pleuritic chest pain. A histopathological confirmation of SCC was made by a video-associated thoracoscopic lung biopsy. Systemic chemotherapy with etoposide and cisplatin was initiated.

Development of the Control Algorithm for the Small PEM Fuel Cell Stack (소형 PEM 연료전지 스택의 제어 알고리즘 개발)

  • Kim, Tae-Hoon;Choi, Woo-Jin
    • The Transactions of the Korean Institute of Power Electronics
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    • v.15 no.2
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    • pp.134-141
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    • 2010
  • Small PEM (Proton Exchange Membrane) fuel cell systems do not require humidification and have great commercialization possibilities. However, methods for controlling small PEM fuel cell stacks have not been clearly established. In this paper, a control method for small PEM fuel cell systems using a dual closed loop with a static feedforward structure is defined and realized using a DSP (Digital Signal Processor). The fundamental elements that need to be controlled in fuel cell systems include the supply of air and hydrogen, water management inside the stack, and heat management of the stack. For small PEM fuel cell stacks operated without a separate humidifier, fans are essential for air supply, heat management, and water management of the stack. A purge valve discharges surplus water from the stack. The proposed method controls the fan using double control loops to quicken transient response of the fan thereby improving the supply rate of air. Feedback control to compensate for the voltage change in fuel cell stack improves the response characteristics in fuel cell to load variations. The feasibility of proposed method was proved by the experiments with a 60W small PEM fuel cell system and operation of a notebook computer using this system.

Cell Virtualization with Network Partition for Initial User Association in Software Defined Small-cell Networks

  • Sun, Guolin;Lu, Li;Ayepah-Mensah, Daniel;Fang, Xiufen;Jiang, Wei
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.12 no.10
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    • pp.4703-4723
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    • 2018
  • In recent years, dense small cell network has been deployed to address the challenge that has resulted from the unprecendented growth of mobile data traffic and users. It has proven to be a cost efficeient solution to offload traffic from macro-cells. Software defined heterogeneous wireless network can decouple the control plane from the data plane. The control signal goes through the macro-cell while the data traffic can be offloaded by small cells. In this paper, we propose a framework for cell virtualization and user association in order to satisfy versatile requirements of multiple tenants. In the proposed framework, we propose an interference graph partioning based virtual-cell association and customized physical-cell association for multi-homed users in a software defined small cell network. The proposed user association scheme includes 3 steps: initialization, virtual-cell association and physical-cell association. Simulation results show that the proposed virtual-cell association outperforms the other schemes. For physical-cell association, the results on resource utilization and user fairness are examined for mobile users and infrastructure providers.

Effect of Interference Mitigation Technique and Performance Analysis for Small Cell in Homogeneous Networks (동종네트워크 상에서 셀 소형화 간섭 완화 기법 및 성능 분석)

  • Jang, Ye-Ok;Cho, Eun-Hyung;Hong, Een-Kee
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.39C no.10
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    • pp.937-945
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    • 2014
  • As various services requiring high data rate are supported by introducing LTE/LTE-adv., mobile traffic increases rapidly. To cope with the continuous growth of traffic demand, small cell technology is considered as one of the most promising one. Small cell can increase system capacity by increasing the number of base stations with reduced cell radius. In this paper, we analyze the effect of cell densification with small cells in terms of SINR and average UE throughput considering cell split and the number of UE per unit area. As the cell becomes smaller, SINR degradation arises from high ICI(Inter Cell Interference) and we evaluate the effect of interference mitigation scheme in small cell environment where the proper interference mitigation technique is applied.

Construction of a Cell-Adhesive Nanofiber Substratum by Incorporating a Small Molecule

  • Jung, Dongju
    • Biomedical Science Letters
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    • v.19 no.1
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    • pp.25-31
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    • 2013
  • Electrospun nanofibers are being widely used as a substratum for mammalian cell culture owing to their structural similarity to collagen fibers found in extracellular matrices of mammalian cells and tissues. Especially, development of diverse synthetic polymers has expanded use of electrospun nanofibers for constructing cell culture substrata. Synthetic polymers have several benefits comparing to natural polymer for their structural consistency, low cost, and capability for blending with other polymers or small molecules to enhance their structural integrity or add biological functions. PMGI (polymethylglutarimide) is one of the synthetic polymers that produced a rigid nanofiber that enables incorporation of small molecules, peptides, and gold nanoparticles through co-electrospinning process, during which the materials are fixed without any chemical modifications in the PMGI nanofibers by maintaining their activities. Using the phenomenon of PMGI nanofiber, here I introduce a construction method of a nanofiber substratum having cell-affinity function towards a pluripotent stem cell by incorporating a small molecule in the PMGI nanofiber.

Performance Analysis of Co- and Cross-tier Device-to-Device Communication Underlaying Macro-small Cell Wireless Networks

  • Li, Tong;Xiao, Zhu;Georges, Hassana Maigary;Luo, Zhinian;Wang, Dong
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.10 no.4
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    • pp.1481-1500
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    • 2016
  • Device-to-Device (D2D) communication underlaying macro-small cell networks, as one of the promising technologies in the era of 5G, is able to improve spectral efficiency and increase system capacity. In this paper, we model the cross- and co-tier D2D communications in two-tier macro-small cell networks. To avoid the complicated interference for cross-tier D2D, we propose a mode selection scheme with a dedicated resource sharing strategy. For co-tier D2D, we formulate a joint optimization problem of power control and resource reuse with the aim of maximizing the overall outage capacity. To solve this non-convex optimization problem, we devise a heuristic algorithm to obtain a suboptimal solution and reduce the computational complexity. System-level simulations demonstrate the effectiveness of the proposed method, which can provide enhanced system performance and guarantee the quality-of-service (QoS) of all devices in two-tier macro-small cell networks. In addition, our study reveals the high potential of introducing cross- and co-tier D2D in small cell networks: i) cross-tier D2D obtains better performance at low and medium small cell densities than co-tier D2D, and ii) co-tier D2D achieves a steady performance improvement with the increase of small cell density.

Cytologic Features of Ascitic Fluid Complicated by Small Cell Variant T-cell Prolymphocytic Leukemia -A Case Report - (복수를 침범한 소세포형 T-세포 전림프구성 백혈병의 세포소견 -1예 보고-)

  • Han, Jee-Young;Kim, Jin-Soo;Kim, Dong-Hoon;Kim, Lucia;Park, In-Suh;Kim, Joon-Mee;Chu, Young-Chae;Choi, Suk-Jin
    • The Korean Journal of Cytopathology
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    • v.19 no.2
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    • pp.168-172
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    • 2008
  • T-cell prolymphocytic leukemia (T-PLL) is a rare, mature T-cell lymphoproliferative disorder with a post-thymic mature T-cell phenotype. The disease is characterized by rapidly rising lymphocytosis, lym-phadenopathy, and splenomegaly. The clinical course is usually aggressive and progresses with frequent skin lesions and serous effusions. In 25% of cases, leukemic cells are small and tumor cells may not have a discrete nucleolus under light microscopy. Although the presence of characteristic cytoplasmic protrusions or blebs in tumor cells is a common morphologic finding in the peripheral blood film irrespective of the nuclear features, small cell variants lacking the typical nuclear features can cause diagnostic problems in clinical cytology. Furthermore, the small leukemic cells can share some cytologic findings with lymphocyte-rich serous effusions caused by non-neoplastic reactive lymphocytosis as well as other small lymphocytic lymphoproliferative disorders. Here, we describe the cytological findings of ascitic fluid complicated by small cell variant T-PLL in a 54-year-old man, the cytology of which was initially interpreted as small lymphocytic malignancy such as small lymphocytic lymphoma/chronic lymphocytic leukemia.

Dynamic Opportunistic Interference Alignment for Random-Access Small-Cell Networks (랜덤 엑세스 스몰셀 무선망에서의 실시간 기회적 간섭정렬 기법 연구)

  • Jeon, Sang-Woon;Shin, Won-Yong
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.39A no.11
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    • pp.675-681
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    • 2014
  • As the recently soaring wireless traffic, small-cell techniques have been actively studied in order to support such a wireless demand for cellular wireless networks. This paper studies interference mitigation methods for random-access small-cell networks. Although inter-cell interference between small random-access cells is one of the main factors to degrade overall performance, most of the previous works focused on interference mitigation between users in each cell. To address such limitation, dynamic opportunistic interference alignment is proposed exploiting statistical characteristics of random-access. It is demonstrated by simulation that the proposed scheme outperforms the previous approach as the number of cells or the number of users in each cell increases.

Primary Small Cell Carcinoma of the Larynx : A Case Report (후두에 발생한 원발성 소세포암종 1예)

  • Choi, Joo Yul;Park, Sung Ho;Kim, Nam Young;Kim, Kyoung Hun;Choi, Ik Joon
    • Korean Journal of Head & Neck Oncology
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    • v.31 no.1
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    • pp.22-26
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    • 2015
  • Small cell carcinoma of larynx has been reported as a rare disease occurring in 0.5% of larynx cancer. This tumor is known as one of the most lethal of all malignancies and associated with early recurrence and distant metastasis, leading into death. We experienced a case of a 70-year old male patient, who had admitted for sore throat and dysphagia and diagnosed as small cell carcinoma of larynx. We present small cell carcinoma of larynx with a brief review of literature.

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Differential Diagnosis between Small Cell Carcinoma and Adenocarcinoma of Lung in Fine Needle Aspiration Cytology (세침흡인 세포검사에서 폐의 소세포암종과 샘암종의 감별진단)

  • Choi, Young-Hee;Koh, Jae-Soo;Park, Sun-Hoo;Kim, Min-Suk;Cho, Soo-Youn;Kim, Jung-Soon;Ha, Hwa-Jung;Lee, Seung-Sook
    • The Korean Journal of Cytopathology
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    • v.17 no.2
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    • pp.120-125
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    • 2006
  • Distinguishing small cell carcinoma from other lung malignancies is of great clinico-therapeutic significance. Small cell carcinoma is an aggressive tumor with a tendency to metastasize early. Survival time if untreated is low but this tumor is highly responsive to chemotherapy. We have occasionally experienced difficulties in differentiation between adenocarcinoma and small cell carcinoma of the lung in fine needle aspiration cytology (FNAC). The aim of this study was to investigate the possibility of distinguishing small cell carcinoma from adenocarcinoma of the lung in FNAC. We evaluated cytomorphological features of FNAC specimens from 62 small cell carcinomas and 57 adenocarcinomas from the lung that were confirmed by biopsy and/or immunohistochemistry on cell block. Cytomorphological details of the two tumors were compared. Nuclear smearing and nearly absent cytoplasm were the most distinct findings in small cell carcinoma compared to adenocarcinoma (p<0.05). Necrotic background, architecture and chromatin pattern, nuclear molding and nucleoli were significantly different (p<0.05). Nuclear size, nuclear membrane nature and nuclear size variation however were not helpful in distinguishing the two tumors. Combining several features described above, small cell carcinoma can be properly differentiated from adenocarcinoma on FNAC. FNAC is proposed as a diagnostic tool of small cell carcinoma of the lung in the case of inaccessibility to biopsy, and so may allow the proper therapeutic strategies to be determined in such cases