• Asian Pacific Journal of Cancer Prevention
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• v.16 no.14
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• pp.5963-5966
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• 2015

Background: This analysis was conducted to evaluate the efficacy and safety of a combination of gemcitabine and nedaplatin in treating patients with non-small cell lung cancer. Methods: Clinical studies evaluating the efficacy and safety of a combination of gemcitabine and nedaplatin with attention to response and safety for patients with non-small cell lung cancer were identified using a predefined search strategy. Pooled response rates for gemcitabine and nedaplatin were calculated. Results: In gemcitabine and nedaplatin based regimens, 4 clinical studies including 112 patients with non-small cell lung cancer were considered eligible for inclusion. The pooled analysis suggested that the pooled reponse rate was 40.2% (45/112). Main side effects included grade 3-4 neutropenia, thrombocytopenia, and anemia. Grade 3-4 nonhematological toxicity included nausea and vomiting, diarrhea, and hepatic dysfunction. There were no treatment-related deaths. Conclusion: This evidence based analysis suggests that the combination of gemcitabine and nedaplatin is associated with good response rate and accepted toxicity for treating patients with non-small cell lung cancer.

• The Journal of Internal Korean Medicine
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• v.36 no.2
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• pp.200-206
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• 2015

Objectives: The purpose of this study is to report the possibility of treatment of locally advanced non-small cell lung cancer with Traditional Korean Medicine based allergen-removed Rhus verniciflua Stokes (ARVS) following chemoradiotherapy. Methods: A patient with locally advanced non-small cell lung cancer (stage IIIB) felt chest discomfort, fatigue, and anxiety after chemoradiotherapy. To prevent recurrence, he opted to receive Traditional Korean Medicine. Results: After treatment with ARVS, the size of the residual primary cancer and a metastatic lymph node decreased, without new cancerous regions. The patient has maintained good performance and has shown prolonged overall survival. Conclusions: This report suggests that ARVS may play a therapeutic role in the treatment of locally advanced non-small cell lung cancer after chemoradiotherapy. Further studies will be needed to determine the effect of ARVS on locally-advanced unresectable non-small cell lung cancer.

• Journal of Internet Computing and Services
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• v.18 no.6
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• pp.7-13
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• 2017

In this paper, we propose a novel dynamic subchannel grouping (DSG) algorithm to maximize the system capacity considering intended proper outage probability for the downlink of enterprise small-cell networks (ESNs). In the proposed DSG scheme, a local gateway (LGW) which is installed in a building dynamically divides the frequency bandwidth into different numbers of subchannel groups (SGs) based on the numbers of small-cell access points (SAPs) and small-cell user equipments (SUEs) per floor. Then, the LGW assigns the SGs to SAPs and the SAPs allocate them to their serving SUEs. Through simulation results, we show that the proposed DSG scheme is appropriate for the ESNs compared to the conventional small-cell networks in which all SAPs use the number of fixed SGs in terms of the system capacity and outage probability.

• Korean Journal of Head & Neck Oncology
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• v.16 no.2
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• pp.216-219
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• 2000

Small cell carcinoma usually occurs in lung, but extrapulmonary small cell carcinomas can occur in any sites of body. Most sites of extrapulmonary small cell carcinoma reported were esophagus. And small cell carcinomas occurred in head and neck area were reported rarely. Extrapulmonary small cell carcinoma could be diagnosed when there is no evidence of primary lung lesion on chest X-ray, CT scan of chest and bronchoscopy. The authors experienced a case of small cell carcinoma of left submandibular lymph node in 64-year-old male patient. Biopsy specimen showed poorly differentiated carcinoma but immunohistochemical study showed small cell carcinoma. The chest X-ray and CT scan of chest showed no evidence of primary lung lesion. The patient received chemotherapy(etoposide plus cisplatin) and concurrent chemoradiotherapy using weekly taxol which resulted in good clinical remission. He is still alive 8 months after diagnosis without evidence of lung disease. We report our case with a brief review of literatures.

• Advances in nano research
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• v.13 no.3
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• pp.297-312
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• 2022

Coughing and breath shortness are common symptoms of nano (small) cell lung cancer. Smoking is main factor in causing such cancers. The cancer cells form on the soft tissues of lung. Deformation behavior and wave vibration of lung affected when cancer cells exist. Therefore, in the current work, phase velocity behavior of the small cell lung cancer as a main part of the body via an exact size-dependent theory is presented. Regarding this problem, displacement fields of small cell lung cancer are obtained using first-order shear deformation theory with five parameters. Besides, the size-dependent small cell lung cancer is modeled via nonlocal stress/strain gradient theory (NSGT). An analytical method is applied for solving the governing equations of the small cell lung cancer structure. The novelty of the current study is the consideration of the five-parameter of displacement for curved panel, and porosity as well as NSGT are employed and solved using the analytical method. For more verification, the outcomes of this reports are compared with the predictions of deep neural network (DNN) with adaptive optimization method. A thorough parametric investigation is conducted on the effect of NSGT parameters, porosity and geometry on the phase velocity behavior of the small cell lung cancer structure.

• International journal of advanced smart convergence
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• v.13 no.1
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• pp.1-11
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• 2024

Cognitive small cell networks, consisting of macro-cells and small cells, are foreseen as a promising candidate solution to address 5G spectrum scarcity. Recently, many technological issues (such as spectrum sensing, spectrum sharing) related to cognitive small cell networks have been studied, but the common control channel (CCC) establishment problem has been ignored. CCC is an indispensable medium for control message exchange that could have a huge significant on transmitter-receiver handshake, channel access negotiation, topology change, and routing information updates, etc. Therefore, establishing CCC in cognitive small cell networks is a challenging problem. In this paper, we propose a potential game theory-based approach for CCC establishment in cognitive radio networks. We design a utility function and demonstrate that it is an exact potential game with a pure Nash equilibrium. To maintain the common control channel list (CCL), we develop a CCC update algorithm. The simulation results demonstrate that the proposed approach has good convergence. On the other hand, it exhibits good delay and overhead of all networks.

• Journal of Chest Surgery
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• v.30 no.2
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• pp.241-245
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• 1997

Primary small cell carcinoma of the esophagus is a very rare cell type in esophageal cancer and an extremely aggresive tumor with grave prognosis. Because of the highly malignant potency, chemotherapy for the primary therapy of small cell carcinoma is accepted generally. We experienced a case of small cell carcinoma of the lower esophagus. The patient was a 53 year-old male with regional Iymph node metastasis and managed with complete resection and chemotherapy.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.9 no.3
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• pp.886-900
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• 2015

Small cells are deployed in Heterogeneous Networks (HetNet) to improve overall performance. These access points can provide high-rate mobile services at hotspots to users. In a Small Cell Network (SCN), the good deployment of small cells can guarantee the performance of users on the basis of average and cell edge spectrum efficiency. In this paper, the performance of small cell deployment is analyzed by using system-level simulations. The positions of small cells can be adjusted according to the deployment radius and angle. Moreover, different Inter-Cell Interference Coordination (ICIC) techniques are also studied, which can be implemented either in time domain or in frequency domain. The network performances are evaluated under different ICIC techniques when the locations of Small evolved Nodes (SeNBs) vary. Simulation results show that the average throughput and cell edge throughput can be greatly improved when small cells are properly deployed with the certain deployment radius and angle. Meanwhile, how to optimally configure the parameters to achieve the potential of the deployment is discussed when applying different ICIC techniques.

• The Korean Journal of Cytopathology
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• v.12 no.2
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• pp.121-125
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• 2001

Primary small cell carcinoma of the urinary bladder is a rare malignant tumor. A more rapidly fatal course may be seen in advanced stages of small cell carcinoma as compared to similar stages of urothelial carcinoma. It is very important to recognize this distinct form of bladder cancer by urinary cytology The differential diagnosis of small cell carcinoma of the urinary bladder includes metastatic small cell carcinoma, urothelial carcinoma, and primary or secondary malignant lymphoma. This article highlights the urinary cytologic diagnosis of a case of primary small cell carcinoma. A 59-year-old male presented with gross hematuria for five months. Urinary cytology showed high cellularity consisting of tiny monotonous tumor cells in the necrotic background. The tumor cells occurred predominantly singly, but a few in clusters. The cytoplasm was so scanty that only a very narrow rim of it was seen. The nuclei were oval or round and had finely stippled chromatin. Rarely, the nuclei contain visible nucleoli. Frequently cell molding was noted in clusters. Many single cells demonstrated nuclear pyknosis or karyorrhexis. The histologic findings of transurethral resection and partial cystectomy specimen were those of small cell carcinoma. Cytologic distinction may be very difficult but careful attention to clinical features and cellualr details can classify these neoplasms correctly.

• Applied Microscopy
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• v.22 no.1
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• pp.15-32
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• 1992

This study was an attempt to investigate and compare the fine structure of small cells in the space of Disse of various animal livers. All animal livers contained small cells with or without lipid droplets and the one with lipid droplet seemed to be more developed and show an abundance of activity in function. The fine structure of the small cells observed in the nonmammals was similar to that of Ito cell in the mammal. The electron density of the small cells was similar to that of other cell types in the same animal liver. The cisternal dilation of rough endoplasmic reticulum and Golgi apparatus was more predominant in the mammalian Ito cells. In the nonmammalian, aquatic vertebrates, however, lysosomes and filaments are much more abundant in the Ito cell and its abundant cytoplasmic processes rich in filaments were usually extended between the parenchymal cells. The disparity in size of organelles and numbers of lipid droplets in the small cells showed a tendency similar to those of other cell types in the same animal. From these results, it is considered that the small cells in the space of Disse is a Ito cell and the Ito cell without lipid droplets differentiates into the one containing lipid droplets according to the characteristics of the different animals respectively, and that the Ito cells in the mammals are more active in metabolic function, while those in the nonmammalian aquatic vertebrates are abundant in support of parenchyme.