• Title/Summary/Keyword: Slope method

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Evaluation of Antioxidant Activity of Sugar Alcohols Using TOSC (Total Oxy-radical Scavenging Capacity) Assay (TOSC 법을 이용한 당알코올의 항산화 활성 평가)

  • Kang, Keon-Wook;Kwak, Sang-Hoon;Yun, Sei-Young;Kim, Sang-Kyum
    • Toxicological Research
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    • v.23 no.2
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    • pp.143-150
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    • 2007
  • Although animal and epidemiological studies have suggested oxidative stress as an etiological factor in pathogenesis including cancer, inflammation, sepsis, fibrosis, cardiovascularlneurodegenerative diseases and aging-related disorders, conflicting results have been obtained in clinical trial with antioxidants. The reason for this discrepancy remains unknown but may be due, in part, to the lack of a validated assay system for evaluating antioxidant capacity. The antioxidant activity of a series of sugar alcohols against peroxyl radicals, hydroxyl radicals and peroxynitrites was determined by the total oxy-radical scavenging capacity (TOSC) assay and cell-based assay using H4IIE cells. Specific TOSC values calculated from the slope of the linear regression for erythritol, xylitol, sorbitol or mannitol against peroxyl radicals was $2.1{\pm}0.2,\;3.7{\pm}0.3,\;9.1{\pm}0.3$ or $8.7{\pm}1.1$ TOSC/mM, respectively. Specific TOSC values for erythritol, xylitol, sorbitol or mannitol against peroxynitrite was $1.9{\pm}0.3,\;3.9{\pm}0.4,\;7.8{\pm}0.7$ or $7.7{\pm}0.5$ TOSC/mM, respectively. These results suggest that oxy-radical scavenging capacity is dependent on the number of aliphatic hydroxyl group in sugar alcohols of monosaccharide. Tert-butylhydroperoxide (t-BHP)-induced cell toxicity determined by MTT assay was marginally attenuated by 10 mM erythritol, but completely inhibited by 10 mM xylitol, 2 mM sorbitol or 0.75 mM maltitol, a disaccharide alcohol. Oxidative stress markers, such as glutathione (GSH) and malondial-dehyde (MDA) levels, were measured in t-BHP-treated cells using HPLC equipped with a fluorescence detector and a reverse phase column. Erythritol did not change the levels of GSH and MDA in H411E cells treated with t-BHP. The t-BHP-induced changes in cellular GSH and MDA levels were ameliorated by 10 mM xylitol and completely blocked by 10 mM sorbitol and maltitol. These results indicate that sugar alcohols protect cells against oxidative stress via scavenging oxy-radical and suggest that TOSC assay in conjunction with cell-based assay is a valid method for evaluating antioxidant capacity of natural and synthetic chemicals.

Eco-corridor Positioning for Target Species - By Field Surveying of Mammals' Road-Kill - (목표종 생태통로의 위치선정 -포유류 Road-kill 현장조사를 중심으로-)

  • Lee, Yong-Wook;Lee, Myeong-Woo
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.9 no.3
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    • pp.51-58
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    • 2006
  • The purpose of this research presents a method to position and makes the structure for eco-corridors reasonably with collectable analysing results of various effects shown in mammals' road-kill at 429 points. Target animals of this research are Leopard cat, Siberian weasel, Raccoon dog, Korean hare, Eurasian red squirrel, Siberian chipmunk and Water deer. The results derived from the empirical analysis on the contents above are followed. First, according to the results as for Leopard cat road kill analysis, which is designated as Endangered Species Class II, the eco-corridor might be located at near village having stead food in order to decrease the frequencies of road-kill, because its road kill points were mainly collected at 4 lane hilly road with mountain-road-farm area geological type of. Second, because Siberian weasel's road kill was detected at 2 lane hilly road with mountain-road-stream geological type, the eco-corridor might be located at near a mill to decrease road-kill frequencies. Third, the road-kill frequency of Eurasian red squirrel can be reduced when the eco-corridor is located at the area across coniferous tree near 4 lane west sea freeway with mountain-road-mountain. Fourth, the road-kill of Raccoon dog can be reduced when the eco-corridor is located at 4 lane mountain road or hilly road with the geological type having farm land-road-mountain(stream). Fifth, Korean hare's road-kill can be reduced when the eco-corridor is located at grass land across ridge line of mountain, because wild rabbit road kill was happened at 4 lane mountain road or 2 lane mountain road(mountain-road-mountain). Sixth, As for Siberian chipmunk, the eco-corridor might be located at the side slope of mountain road at 2 lane mountain road under the speed of 60km/h with mountain-road-mountain. Seventh, For Water deer, the eco-corridor might be located at 4 lane hilly road with mountain-road-farm land. As for Common otter, Amur hedgehog, Yellow-throated marten, Weasel, it is difficult to specify the proper site of eco-corridor due to the lack of data. Eco-corridors for carnivores might be well located at 4 lane hilly road or 2 lane hilly road with mountain-road-farm land, and the track for herbivores might be well located as a overhead bridge on mountain-road-mountain type across mountains. In order to position eco-corridors for wildlife properly, we have to research animal's behavior with ecological background, and to consider the local uniqueness and regularly collect the empirical road-kill data in long term 3 to 5 year, which can be the foundation for the more suitable place of wild life eco-corridors.

Some considerations for the determination of carbonyl compounds in air: Reaction characteristics of formaldehyde with 2.4-DNPH (대기 중 카보닐 계열 성분의 분석기법의 연구: 포름알데하이드와 DNPH의 반응 특성을 중심으로)

  • Hong, Y.J.;Kim, K.H.
    • Analytical Science and Technology
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    • v.18 no.1
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    • pp.43-50
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    • 2005
  • A number of carbonyl compounds including formaldehyde and acetaldehyde are well known for their toxicity and irritancy. Hence, acquisition of both qualitative and quantitative tool for their analysis is essential to resolve issues associated with malodor or indoor pollution. Using HPLC/UV method, we examined various aspects involved in the measurements of formaldehyde in environmental samples. The results of our analysis indicated that its detection was made as low as 0.5 ppb (assuming 5 L of sample volume), while its precision was maintained near 2% in terms of relative standard error (RSE). When the stability of calibration was checked by variability of slope values obtained over long-term period (e.g., one month), its values were found to remain constantly with RSE values of 3%. It was also found that liquid-phase reaction between formaldehyde and DNPH proceed very slowly to attain equilibrium (one and half hour), while requiring adequate amount of DNPH to form their derivatives. The overall results of our study thus suggest that there are a number of factors to consider for the accurate analysis of formaldehyde in ambient air.

A fundamental study on the jet fan capacity for smoke control considering thermal buoyancy force in tunnel fires (터널 화재 시 열부력을 고려한 제연용 제트팬 용량산정에 관한 기초 연구)

  • Lee, Ho-Hyung;Choi, Pan-Gyu;Jo, Jong-Bok;Lee, Seung-Chul;Lee, Chang-Woo
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.20 no.2
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    • pp.501-511
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    • 2018
  • As a result of the recent revision of the 'Guideline for Installation and Management of Fire Prevention Facility in Road Tunnels', the thermal buoyancy has to be taken into account when calculating the capacity of jet fans for smoke control in tunnel fires. However, there is no detailed methodologies for considering thermal buoyancy, so further study is needed. In this study, the thermal buoyancy in the tunnel is calculated by 3-D numerical simulation to consider the thermal buoyancy in case of fire in tunnels, and the relationship between heat buoyancy and vehicle drag, And the method of calculating the capacity of the jet fan for smoke control in tunnels. According to the analysis results, heat buoyancy acts as a resistance force in the case of a down-slope tunnel, and the pressure rise of jet fan for smoke control is not simply determined by the value of heat buoyancy at the entrance of the tunnel and the value of the vehicle drag at the exit. And it is analyzed that it is necessary to carry out a comprehensive review according to the location of the fire vehicle in tunnels.

Analysis of Land Surface Temperature from MODIS and Landsat Satellites using by AWS Temperature in Capital Area (수도권 AWS 기온을 이용한 MODIS, Landsat 위성의 지표면 온도 분석)

  • Jee, Joon-Bum;Lee, Kyu-Tae;Choi, Young-Jean
    • Korean Journal of Remote Sensing
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    • v.30 no.2
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    • pp.315-329
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    • 2014
  • In order to analyze the Land Surface Temperature (LST) in metropolitan area including Seoul, Landsat and MODIS land surface temperature, Automatic Weather Station (AWS) temperature, digital elevation model and landuse are used. Analysis method among the Landsat and MODIS LST and AWS temperature is basic statistics using by correlation coefficient, root-mean-square error and linear regression etc. Statistics of Landsat and MODIS LST are a correlation coefficient of 0.32 and Root Mean Squared Error (RMSE) of 4.61 K, respectively. And statistics of Landsat and MODIS LST and AWS temperature have the correlations of 0.83 and 0.96 and the RMSE of 3.28 K and 2.25 K, respectively. Landsat and MODIS LST have relatively high correlation with AWS temperature, and the slope of the linear regression function have 0.45 (Landsat) and 1.02 (MODIS), respectively. Especially, Landsat 5 has lower correlation about 0.5 or less in entire station, but Landsat 8 have a higher correlation of 0.5 or more despite of lower match point than other satellites. Landsat 7 have highly correlation of more than 0.8 in the center of Seoul. Correlation between satellite LSTs and AWS temperature with landuse (urban and rural) have 0.8 or higher. Landsat LST have correlation of 0.84 and RMSE of more than 3.1 K, while MODIS LST have correlation of more than 0.96 and RMSE of 2.6 K. Consequently, the difference between the LSTs by two satellites have due to the difference in the optical observation and detection the radiation generated by the difference in the area resolution.

Availability Analysis on Detection of Small Scale Gas Emission Facilities using Drone Imagery (드론영상을 이용한 소규모 가스 배출시설 탐지 가능성 분석)

  • Shin, Jung-Il;Kim, Ik-Jae;Hwang, Dong-Hyun;Lee, Jong-Min;Lim, Seong-Ha
    • Journal of Cadastre & Land InformatiX
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    • v.47 no.1
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    • pp.213-223
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    • 2017
  • Recently, the air quality of South Korea has deteriorated and public interest has been increasing. Various observation means are used for the monitoring of the atmospheric environment, but it relies on the experience and judgment of the observer in the absence of spatial information on the emission facilities. The purpose of this study was to determine the availability of using drones for monitoring air pollutant emission facilities. A texture transformation method was applied to the drone ortho image to detect the small gas emission facility and the slope data calculated by the digital surface model (DSM) was used to reduce the false alarm ratio. As a result, it shows the possibility of using drones in the detection of small gas emission facilities by showing about 80% of positive detection ratio and 40% of false alarm ratio. In the future, various researches are required to the improve positive detection ratio and the reduction of the false alarm ratio. Based on these results, it is necessary to construct a database including 3D spatial information of air pollutant emission facilities.

Improvement of Mechanical Properties of Mg alloys through Control of Grain Size and Texture (결정립크기와 집합조직제어를 통한 마그네슘 합금의 기계적 성질 개선)

  • Kim, W.J.;Lee, J.B.;Kim, W.Y.;Jeong, H.G.;Park, J.D.
    • Proceedings of the Korean Society for Technology of Plasticity Conference
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    • 2006.05a
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    • pp.57-58
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    • 2006
  • The effects of lowering ECAP temperature during ECAP process and Post-ECAP annealing on microstructure, texture and mechanical properties of the AZ31 alloys have been investigated in the present study. The as-extruded materials were ECAP processed to 2 passes at 553K prior to subsequent pressing up to 6 passes at 523K or 493K. When this method of lowering ECAP temperature during ECAP was used, the rods could be successfully deformed up to 6 passes without any surface cracking. Grain refinement during ECAP process at 553K might have helped the material to endure further straining at lower deformation temperatures probably by increasing the strain accommodation effect by grain boundary sliding, causing stress relaxation. Texture modification during ECAP has a great influence on the strength of Mg alloys because HCP metals have limited number of slip systems. As slip is most prone to take place on basal planes in Mg at room temperature, the rotation of high fraction of basal planes to the directions favorable for slip as in ECAP decreases the yield stress appreciably. The strength of AZ31 Mg alloys increases with decrease of grain size if the texture is constant though ECAP deformation history is different. A standard positive strength dependence on the grain size for Mg alloys with the similar texture (Fig. 1) supports that the softening of ECAPed Mg alloys (a negative slope) typically observed despite the significant grain refinement is due to the texture modification where the rotation of basal planes occurs towards the orientation for easier slip. It could be predicted that if the original fiber texture is restored after ECAP treatment yielding marked grain refinement, yield stress as high as 500 MPa will be obtained at the grain size of ${\sim}1{\mu}m$. Differential speed rolling (DSR) with a high speed ratio between the upper and lower rolls was applied to alter the microstructure and texture of the AZ31 sheets. Significant grain refinement took place during the rolling owing to introduction of large shear deformation. Grain size as small as $1.4{\mu}m$ could be obtained at 423K after DSR. There was a good correlation between the (0002) pole intensity and tensile elongation. This result indicates that tensile ductility improvement in the asymmetrically rolled AZ31 Mg alloys is closely related to the weakening of basal texture during DSR. Further basal texture weakening occurred during annealing after DSR. According to Hall-Petch relation shown in Fig. 1, the strength of the asymmetrically rolled AZ31 is lower than that of the symmetrically rolled one when compared at the same grain size. This result was attributed to weakening of fiber texture during DSR. The DSRed AZ31, however, shows higher strength than the ECAPed AZ31 where texture has been completely replaced by a new texture associated with high Schmid factors.

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A Geomorphological Classification System to Chatacterize Ecological Processes over the Landscape (생태환경 특성 파악을 위한 지형분류기법의 개발)

  • Park Soo-Jin
    • Journal of the Korean Geographical Society
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    • v.39 no.4
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    • pp.495-513
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    • 2004
  • The shape of land surface work as a cradle for various environmental processes and human activities. As spatially distributed process modelings become increasing important in current research communities, a classification system that delineates land surface into characteristic geomorphological units is a pre-requisite for sustainable land use planning and management. Existing classification systems are either morphometric or generic, which have limitations to characterize continuous ecological processes over the landscape. A new classification system was developed to delineate the land surface into different geomorphological units from Digital Elevation Models(DEMs). This model assumes that there are pedo-geomorphological units in which distinct sets of hydrological, pedological, and consequent ecological processes occur. The classification system first divides the whole landsurface into eight soil-landscape units. Possible energy and material nows over the land surface were interpreted using a continuity equation of mass flow along the hillslope, and subsequently implemented in terrain analysis procedures. The developed models were tested at a 12$\textrm{km}^2$ area in Yangpyeong-gun, Kyeongi-do, Korea. The method proposed effectively delineates land surface into distinct pedo-geomorphological units, which identify the geomorphological characteristics over a large area at a low cost. The delineated landscape units mal provide a basic information for natural resource survey and environmental modeling practices.

Generation Rate and Content Variation of Manganese in Stainless Steel Welding (스테인레스 강 용접중 발생하는 망간의 발생량 및 함량변화에 관한 연구)

  • Yoon, Chung Sik;Kim, Jeong Han
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.16 no.3
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    • pp.254-263
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    • 2006
  • Manganese has a role as both toxic and essential in humans. Manganese is also an essential component in the welding because it increases the hardness and strength, prevents steel from cracking of welding part and acts as a deoxidizing agent to form a stable weld. In this study, manganese generation rate and its content was determined in flux cored arc welding on stainless steel. Domestic two products and foreign four products of flux cored wires were tested in the well designed fume generation chamber as a function of input power. Welding fume was measured by gravimetric method and metal manganese was determined by inductively coupled plasma-atomic emission spectrophotometer. The outer shell of the flux cored wire tube and inner flux were analyzed by scanning electron microscopy to determine their metal compositions. Manganese generation rate($FGR_{mn}$) was increased as the input power increased. It was 16.3 mg/min at the low input power, 38.1 mg/min at the optimal input power, and up to 55.4 mg/min at the high input power. This means that $FGR_{mn}$ is increased at the work place if welder raise the current and/or voltage for the high productivity. The slope coefficient of $FGR_{mn}$ was smaller than that of the generation rate of total fume(FGR). Also, the correlation coefficient of $FGR_{mn}$ was 0.65 whereas that of FGR is 0.91. $FGR_{mn}$ was equal or higher in the domestic products than that of the foreign products although FGR was similar. From the electron microscopic analytical data, we concluded that outer shell of the wire was composed mainly of iron, chromium, nickel and less than 1.2 % of manganese. There are many metal ingredients such as iron, silica, manganese, zirconium, titanium, nickel, potassium, and aluminum in the inner flux but they were not homogeneous. It was found that both $FGR_{mn}$ and content of manganese was higher and more varied in domestic flux cored wires than those of foreign products. To reduce worker exposure to fumes and hazardous component at the source, further research is needed to develop new welding filler materials that improve the quality of flux cored wire in respect to these points. Welder should keep in mind that the FGR, $FGR_{mn}$ and probably the generation rate of other hazardous metals were increased as the input power increase for the high productivity.

Location Accuracy Analysis and Accuracy Improvement Method of Pattern Matching Algorithm Using Database Construction Algorithm (패턴매칭 알고리즘의 측위 성능 분석 및 데이터베이스 구축 알고리즘을 이용한 정확도 향상 방법)

  • Ju, Yeong-Hwan;Park, Yong-Wan
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.46 no.4
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    • pp.86-94
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    • 2009
  • Currently, positioning methods for LBS(Location Based Service) are GPS and network-based positioning techniques that use mobile communication networks. In these methods, however, the accuracy of positioning decreases due to the propagation delay caused by the non-line-of-sight(NLOS) effect and the repeater. To address this disadvantage, the CDMA system uses Pattern Matching algorithm. The Pattern Matching algorithm constructs a database of the propagation characteristics of the RF signals measured during the GPS positioning along with the positioned locations, so that the location can be provided by comparing the propagation characteristics of the received signals and the database, upon a user's request. In the area where GPS signals are not received, however, a database cannot be constructed. There are problem that the accuracy of positioning decreases due to the area without a database Because Pattern Matching algorithm depend on database existence. Therefore, this paper proposed a pilot signal strength prediction algorithm to enable construction of databases for areas without databases, so as to improve the performance of the Pattern Matching algorithm. The database was constructed by predicting the pilot signals in the area without a database using the proposed algorithm, and the Pattern Matching algorithm analysed positioning performance.