• Science of Emotion and Sensibility
• /
• v.19 no.4
• /
• pp.13-20
• /
• 2016

Recently, life-logging service which has expanded to measure and record the daily life of the users and to share with others are increasing. In particular, as life-logging services based on the application has become popular with the development of wearable-devices and smart-phones, the contents of this service are produced by user behavior and are provided in infographic menu form. The purpose of this paper is to extract user behavior and classify for making contents items of life-logging service. For this paper, the first of all, we discuss the definition and characteristics of life-logging and research the contents based on user behavior related to life-logging by the publications including thesis, articles, and books. Secondly, we extract and classify the user behavior to build the contents for life-logging service. We gather users' action words from publication materials, researches, and contents of existing life-logging service. And then collected words are analyzed by FGI (Focus Group Interview) and survey. As the result, 39 words which suit for contents of life-logging service are extracted by verify suitability. Finally, the extracted 39 words are classified for 19 categories -'Eat', 'Keep house', 'Diet', 'Travel', 'Work out', 'Transit', 'Shoot', 'Meet', 'Feel', 'Talk', 'Care for', 'Drive', 'Listen', 'Go online', 'Sleep', 'Go', 'Work', 'Learn', 'Watch' - which are suggested by the surveys, statistical analysis, and FGI. We will discuss the role and limitations of this results to build contents configuration based on life-logging application in this study.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.16 no.2
• /
• pp.1207-1215
• /
• 2015

The smartphone addiction research to identify the pattern according to your smartphone addiction. Recovery of 689 to 1429 parts by distributing the total recovery is 48.22%, respectively. Were utilized to study 650 data. Smartphone addiction group was divided into low, group care, group into three groups according to the degree of severity smartphone addiction. The response that smartphone addiction severity group 135 people 86.5%, lower addiction group 59 people% smartphone smartphones note 165 people group 50.2%, 35.5 'no' do you think about the own smartphone addiction (p <0.001). Showed that exceeds 50% of the smartphone severe poisoning group and attention should use having a chat group with respect to the smart phone. Also showed that beyond a midnight bed time group the more severe the smartphone addiction. Usual findings for bedtime showed a tendency to sleep late pass midnight smartphone addiction show higher water shortage phenomenon. Could be used as the basis for the study which may be a healthy life to predict the degree of occurrence of a pattern according to the type of smart phone poisoning by identifying the factors of the individual according to the degree of poisoning smartphone pattern.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.12 no.9
• /
• pp.3887-3896
• /
• 2011

This study was intended to measure the level of psychosocial stress among nurses working for a university hospital and to reveal its related factors. The self-administered questionnaires were given to 450 nurses during the period from October 1st to 31st, 2010. As a results, the level of psychosocial stress was 10.2% in normal group, 64.0% in potential stresses group, and 25.8% in high risk stress group. In correlation, psychosocial stress was positively correlated with job demand, but it was negatively correlated with job autonomy, supervisor and colleague support. For the results of hierarchial multiple regression analysis, the level of psychosocial stress was influenced by the variables of regular exercise, quality of sleep, subjective status of health, shift work, fit to the job, job demand, job autonomy and supervisor support. Especially, the psychosocial stress was higher related with the contents of job stress increased with explanatory powers of 18.1% on the psychosocial stress.

• Allergy, Asthma & Immunology Research
• /
• v.10 no.6
• /
• pp.628-647
• /
• 2018

Purpose: Obesity is associated with metabolic dysregulation, but the underlying metabolic signatures involving clinical and inflammatory profiles of obese asthma are largely unexplored. We aimed at identifying the metabolic signatures of obese asthma. Methods: Eligible subjects with obese (n = 11) and lean (n = 22) asthma underwent body composition and clinical assessment, sputum induction, and blood sampling. Sputum supernatant was assessed for interleukin $(IL)-1{\beta}$, -4, -5, -6, -13, and tumor necrosis factor $(TNF)-{\alpha}$, and serum was detected for leptin, adiponectin and C-reactive protein. Untargeted gas chromatography time-of-flight mass spectrometry (GC-TOF-MS)-based metabolic profiles in sputum, serum and peripheral blood monocular cells (PBMCs) were analyzed by orthogonal projections to latent structures-discriminate analysis (OPLS-DA) and pathway topology enrichment analysis. The differential metabolites were further validated by correlation analysis with body composition, and clinical and inflammatory profiles. Results: Body composition, asthma control, and the levels of $IL-1{\beta}$, -4, -13, leptin and adiponectin in obese asthmatics were significantly different from those in lean asthmatics. OPLS-DA analysis revealed 28 differential metabolites that distinguished obese from lean asthmatic subjects. The validation analysis identified 18 potential metabolic signatures (11 in sputum, 4 in serum and 2 in PBMCs) of obese asthmatics. Pathway topology enrichment analysis revealed that cyanoamino acid metabolism, caffeine metabolism, alanine, aspartate and glutamate metabolism, phenylalanine, tyrosine and tryptophan biosynthesis, pentose phosphate pathway in sputum, and glyoxylate and dicarboxylate metabolism, glycerolipid metabolism and pentose phosphate pathway in serum are suggested to be significant pathways related to obese asthma. Conclusions: GC-TOF-MS-based metabolomics indicates obese asthma is characterized by a metabolic profile different from lean asthma. The potential metabolic signatures indicated novel immune-metabolic mechanisms in obese asthma with providing more phenotypic and therapeutic implications, which needs further replication and validation.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.32 no.1
• /
• pp.32-41
• /
• 2019

Objective : The purpose of this study is to develop a personal health record(PHR) application of atopic dermatitis in Korean Medicine(KM). Methods : We have identified the items necessary to provide an PHR application that helps to record and manage the symptoms of an atopic dermatitis in KM. We also derived the symptom collection process and method and applied it to the application. Results : In this study, the types of symptoms collected for atopic dermatitis were derived. Symptoms include daily check, stool/urine/sleep, daily emotion, meal management, symptom photographs, SCORAD, quality of life, progress check, original symptom, pediatric health check, weakness check, and subjective symptoms. The recording cycle can be divided into the first, daily, weekly, specific day, and subjective. We developed the PHR application of atopic dermatitis in KM by deriving the type of symptoms and symptom recording process. The app organized menus into dashboards, checklists, daily checks, and health records. Conclusions : We developed a PHR application for atopic dermatitis by deriving symptom collection items of atopic dermatitis and developing symptom collection process and collection technique. The app does not make an accurate diagnosis of atopic dermatitis symptoms, but it helps facilitate symptom collection and helps to identify or predict a person's health condition. It can also be used for medical treatment through sharing symptoms with Korean medicine. Patients are able to communicate in both directions on a daily, weekly, self-aware basis, at the request of a doctor, to record their symptoms and use them for medical purposes. If the doctor asks for a progress check to refer to the next examination, it can be written through the system. This manages atopic dermatitis in daily life and can be used in the clinical field.

• Journal of Life Science
• /
• v.31 no.2
• /
• pp.183-191
• /
• 2021

Euglena gracilis is a microalga of great biotechnological interest that can create high levels of bioactive compounds, such as tocopherol, paramylon, and folic acid. The objective of this study was to investigate the biological activities of extracts from E. gracilis, especially those focused on immunological activity. E. gracilis biomass was extracted with hot water (HWE) and the remaining pellet was continuously extracted with methanol (HWME). First, we examined the effect of two extracts from E. gracilis on the production of nitric oxide (NO) and the expression of pro-inflammation cytokines, including IL-1β, IL-6, and TNF-α in murine macrophage RAW 264.7 cells. HWE treatment dose-dependently increased the production of IL-1β and TNF-α. On the other hand, treatment with HWME significantly decreased the generation of NO and pro-inflammatory cytokines (IL-6 and TNF-α) in lipopolysaccharide (LPS)-stimulated macrophage cells. In addition, other biological activities of the extracts were further analyzed: α-glucosidase inhibition, protein tyrosine phosphatase (PTP1B) inhibition, tyrosinase inhibition, xanthine oxidase (XO) inhibition, and angiotensin-converting enzyme (ACE) inhibition. Analysis of these biological activities showed that HWE has more inhibitory effects than HWME against α-glucosidase, tyrosinase, and XO agents. However, the inhibition of PTP1B and ACE with HWME were higher than with HWE. Taken together, the results suggested that E. gracilis possesses various biological activities―especially immunological capabilities―through regulation of cytokine production. Therefore, E. gracilis extract may be potentially useful for food material with immune-regulating effects.

• 한국노년학
• /
• v.28 no.4
• /
• pp.1069-1087
• /
• 2008

The purpose of this study was to closely examine the effects of aromatherapy on Behavioral and Psychological Symptoms of Dementia(BPSD) to the elderly in a nursing home, and to help the application of aromatherapy is expected to be conducive to managing the quality life in the dementia and the care-giver, and to provide a base of the aromatherapy application as an elderly program in geriatric institutions. This is an one group pre-post test design and the research subjects were the dementia in a nursing home those were totally 15 available for communication or intention observation. Aromatherapy was offered for 3 weeks totally 15 times by once a day in each with aroma hand massage and inhalation, by blending essential oils, Lavender, Chamomile Roman and Grapefruit. The results are as follows. Given examining a change in the whole about whether there are effects of aromatherapy on BPSD, there was significant difference in a change depending on the experimental period with 1.47 for the pre-measurement value, 1.09 for the post 1-measurement value, 1.01 for the post 2-measurement value and 0.71 for the post 3-measurement value. And, even the difference in experimental period was indicated to have significant difference(F=11.501, p<0.001). As an itemized results, the effect of aromatherapy were indicated to have significant difference on easing the anxiety, anguish, fear, dreadful feeling, depressed feeling, and outstandingly bustling movement, and outstandingly inactive behavior, and sleep disturbance and behavior of wandering about at night. On the basis of the result in this study, the application of aromatherapy is expected to lead the quality life in the dementia, and to contribute to health of mind and body in the dementia as an program in geriatric institutions.

• Journal of Microbiology and Biotechnology
• /
• v.32 no.8
• /
• pp.1017-1025
• /
• 2022

Bone homeostasis is regulated by constant remodeling through osteogenesis by osteoblasts and osteolysis by osteoclasts and osteoporosis can be provoked when this balance is broken. Present pharmaceutical treatments for osteoporosis have harmful side effects and thus, our goal was to develop therapeutics from intrisincally safe natural products. Fucoidan is a polysaccharide extracted from many species of brown seaweed, with valuable pharmaceutical activities. To intensify the effect of fucoidan on bone homeostasis, we hydrolyzed fucoidan using AMG, Pectinex and Viscozyme. Of these, fucoidan biotransformed by Pectinex (Fu/Pec) powerfully inhibited the induction of tartrate-resistant acid phosphatase (TRAP) activity in osteoclasts differentiated from bone marrow macrophages (BMMs) by the receptor for activation of nuclear factor-κB ligand (RANKL). To investigate potential of lower molecular weight fucoidan it was separated into >300 kDa, 50-300 kDa, and <50 kDa Fu/Pec fractions by ultrafiltration system. The effects of these fractions on TRAP and alkaline phosphatase (ALP) activities were then examined in differentiated osteoclasts and MC3T3-E1 osteoblasts, respectively. Interestingly, 50-300 kDa Fu/Pec suppressed RANKL-induced osteoclasts differentiation from BMMs but did not synergistically enhance osteoblasts differentiation induced by osteogenic agents. In addition, this fraction inhibited the expressions of NFATc1, TRAP, OSCAR, and RANK, which are all key transcriptional factors involved in osteoclast differentiation, and those of Src, c-Fos and Mitf, as determined by RT-PCR. In conclusion, enzymatically low-molecularized 50-300 kDa Fu/Pec suppressed TRAP by downregulating RANKL-related signaling, contributing to the inhibition of osteoclasts differentiation, and represented a potential means of inducing bone remodeling in the background of osteoporosis.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.22 no.5
• /
• pp.411-422
• /
• 2021

The purpose of this study is to examine the relationships between quality of life and demographic characteristics and health-related behavioral characteristics, and their relevance to variables that represent health conditions among metropolitan-dwelling older adults. The study subjects were 380 senior citizens aged 65 or older living in the D metropolitan area, and data collection was conducted by visiting them for interviews in June 2019. A binomial logistic regression analysis was performed to examine the relationship between independent variables (demographic characteristics, health-related behavioral characteristics, health condition variables) and the dependent variable (quality of life) while controlling for gender and age. As a result, the factors related to quality of life for those surveyed were education level, spousal status, living status, bear for living expenses, average monthly allowance, satisfaction with daily life, evaluation of sleep quality, smoking and eating habits, amount of regular exercise, hobbies, subjective health status, physical disability (if any), hearing ability, visual acuity, mastication ability, urinary incontinence (present or not), and amnesia. The above results suggest that quality of life for the elderly living in urban areas is significantly related to variables that indicate demographic characteristics, health-related behavioral characteristics, and health condition.

• Journal of Oriental Neuropsychiatry
• /
• v.35 no.2
• /
• pp.191-203
• /
• 2024

Objectives: To evaluate the effectiveness of an integrated medical service model for a fibromyalgia patient and their caregiver, focusing on reducing pain and improving quality of life. Methods: A single-case study design was employed, involving a fibromyalgia patient and their primary caregiver treated at W University Hospital. The integrated medical service program, based on the Ministry of Health and Welfare's model, included medical consultations and complementary therapies such as psychological counseling, art therapy, music therapy, horticultural therapy, yoga, and meditation. The program was conducted weekly for 8 weeks, with each session lasting up to 100 minutes. Data collection involved both quantitative and qualitative assessments. Quantitative data included demographic surveys, psychological tests, health-related quality of life measures, pain indices, and sleep quality indices. Qualitative data were gathered through feedback evaluations and emotional assessments. Results: The patient showed improvements in mobility, self-care, daily activities, and anxiety/depression, with EQ-VAS scores increasing from 20 to 40 and pain perception decreasing from 67.41 to 42.58. The caregiver reported reduced anxiety/depression and an increase in EQ-VAS scores from 95 to 98. Both patient and caregiver exhibited emotional changes, with decreased depression and increased happiness. However, the patient showed an increase in fear and anger. Conclusions: The integrated medical service model positively impacted the emotional and psychological well-being of the fibromyalgia patient and their caregiver. Despite the limitations of a small sample size and a single-case study design, the findings suggest that an integrated approach can be beneficial. Larger-scale studies are needed to confirm and generalize these results.