• Journal of Convergence for Information Technology
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• v.10 no.8
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• pp.179-186
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• 2020

The purpose of this study was to investigate the effects on the bio signal of brain waves and pulse waves using acupressure thermal bed combined with acupressure and thermal therapy. Forty healthy adults were divided into 20 experimental groups using combinatorial stimulation beds and 20 non-irritating controls. As a result of the experiment, the EEG was significantly increased in the delta wave and theta wave in the experimental group, and the alpha wave and beta wave decreased significantly. The pulse wave increased the parasympathetic activity index in the experimental group and the heart rate decreased. There was no difference in the control group. This change in EEG can be seen as a combination stimulation bed having a sleep-inducing effect, and a change in pulse wave can seen as having a relaxing effect. This study is expected to be used as basic data for the development of various combination stimulators and functional bed products.

• Proceedings of the ESK Conference
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• 1998.04a
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• pp.167-172
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• 1998

Methods of evaluating the physiological activity of the living body are EEG, EOG, Heart rate, and Rectal temperature, etc. In the study of Hagiwara and Araki(1993), they found positive correlations among performance test, physiological measurement, and subjective feeling measurement. Human alertness of pilot directly influences on the flight performance that accomplishes a lot of vigilance task and procedure execution in flight. Accordingly, this paper deals with the quantitative and objective performance test based on tracking error and reaction time by means of the new computer test program into which the perception-motion system of human beings is applies. Throughout this experiment using performance thst, the results suggest that performance capability in state of sleep deprivation 2 hours and alcoholic 0.05 .apaprox. 0.06% in blood were more impaired than one in a normal state, and they further showed statistically significant differences between them, which were influenced by impairment factors of body regulation and pilot's grade. We also obtained the prediction value and the 95% confidence interval of tracking error and reaction time at the normal state for the purpose of distinguishing performance capability between the normal state and the abnormal state. And it is ecpected that the evaluation of human alertness using performance test will be applied to the quantitative assessment of an each pilot's realistic consciousness/attention, and will lead a flight commander to the accurate decision of mission approval prior to a flight.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.13 no.9
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• pp.4518-4540
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• 2019

With the development of IT convergence technology, autonomous driving has gradually developed; however, the vehicle is still operated by the driver, who should always be in good health - but sometimes, this is not the case. It is especially dangerous to drive when drowsy, and unable to fully concentrate on driving, such as when taking certain medicines, or through fatigue. Drowsy driving is at least eight times more dangerous than normal driving, and as dangerous as drunk driving. Previous research has looked at technology to detect drowsiness, in order to wake up drivers when necessary, or to safely stop the vehicle. Furthermore, many studies have been conducted to find out when drowsiness occurs. However, it is more desirable for the driver to take sufficient rest during a break, in order to be able to continue to focus and drive. In other words, it is important to maintain a normal state before drowsiness. In this study, we introduce a sound source to increase driver concentration and prevent drowsiness, another that can improve the quality of sleep, and a system that produces these sound sources. The proposed system has a noise reduction effect of about 15 dB. We have confirmed that the proposed sound induces an EEG of the desired form.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.3
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• pp.447-452
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• 2020

The purpose of this research was to confirm that prefrontal neurofeedback training has an impact on adolescents. The objective of this study was to prove its scientific effect through experimentation. The effect of the training was measured by the difference in neuro?frequencies before and after the training. For this research, an experimental group and a control group, each with 22 students in J High School located in the city of S participated in this study. From May to July 2019, the training was conducted three times a week and for 30 minutes per session. The neuro?frequency data collected were analyzed through the methods of F.F.T. The resulting changes from the neurofeedback training for each group were analyzed by T-Tests. The result of the study is as follows; Neurofeedback training has had a positive effect on adolescent attention and sleep. In conclusion, the environmental and educational factors also play an important role. As the interaction of the latter two factors yield an individual's unique brain structure and functionality, the impact of the neurofeedback training is important on adolescents. The derivation of the above results by utilizing scientific and objective methods reemphasizes the importance of this study.

• Clinical and Experimental Pediatrics
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• v.45 no.3
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• pp.383-389
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• 2002

We experienced a case of partial DiGeorge syndrome in a $35^{＋5}$ week premature female infant presented with micrognathia, fish-shaped mouth, beaked nose, nasal regurgitation, obstructive sleep apnea, velopharyngeal insufficiency and late onset hypocalcemic seizures. The chromosome 22q11 microdeletion was found by the FISH method. The lab findings showed serum calcium level of 4.4 mg/dL, ionized calcium level of 0.49 mg/dL, phosphorous level of 7.5 mg/dL, magnesium level of 1.3 mg/dL and PTH-RIA level of <1 pq/mL. Initial treatment was done with 10% calcium gluconate infusion and magnesium sulfate followed by oral calcium gluconate and low phosphorousformula milk feeding. The serum calcium level was normalized in 6 days. Nasal regurgitation, desaturation with obstructive sleep apnea continued. T-cell functions & numbers(CD 3, CD 4, CD 8)were decreased but Ig G/A/M levels were normal. No visible signs of thymus shadow were seen in either chest X-ray & chest MRI. Electrocardiography and echocardiography showed normal heart. Kidney ultrasonographby showed right side mild hydronephrosis. Neurosonography was normal but EEG showed electrical partial seizure. Hearing assessment by BERA showed mild to moderate hearing impairment. Velopharyngoplasty is scheduled for further treatment. A brief review of literature was made.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 1999.11a
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• pp.38-42
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• 1999

문명의 발달과 함께 인간은 사회생활의 증가와 부족한 수면으로 인한 스트레스와 병이 증가하고 있다. 따라서 수면에 대한 관심이 증가하면서 편안하고 쾌적한 수면을 위한 수면환경에 대한 연구가 진행되어지고 있다. 본 연구는 쾌적한 온열환경 제시를 위한 방법으로서 여름철 실내환경이 수면에 미치는 영향을 알아보기 위해 22$^{\circ}C$, 26$^{\circ}C$, 3$0^{\circ}C$의 3가지 온도조건을 제시하고 5명의 피험자를 대상으로 수면다원검사를 실시하여 EEG, EOG, ECG, EMG 등의 생리신호를 측정하였다. 측정된 생리신호를 통해 수면단계분석과 수면효율을 분석한 결과 총 수면시간, SWS latency, 총 수면시간에 대한 SWS 시간의 비율이 26$^{\circ}C$의 조건에서 가장 좋은 결과를 나타내었으며, 22$^{\circ}C$, 3$0^{\circ}C$의 순서로 나타났다. 이러한 분석을 통해 온도차에 따라 수면상태가 달라짐을 관찰할 수 있었고, 여름철에 26$^{\circ}C$ 정도의 실내온도가 편안하고 쾌적한 수면을 위한 실내온열환경임을 알 수 있었다.

• Sleep Medicine and Psychophysiology
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• v.20 no.2
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• pp.75-81
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• 2013

Objectives: There are a lot of studies that analyze the interaction between the emotion of disgust and the functional brain images using fMRI and PET. But studies using sLORETA (standardized low resolution brain electromagnetic tomography) almost do not exist. The aim of this research is to explore the relationship of the emotion of disgust and the cortical activation using sLORETA analysis. Methods: Forty five healthy young adults ($27.1{\pm}2.6$ years) participated in the study. While they were watching 4 neutral images and 4 disgusting images associated with mutilation selected from the international affective picture system (IAPS), participants' EEGs were taken for 30 seconds per one picture. Through these obtained EEG data, sLORETA analysis was performed to compare EEGs associated with neutral and negative images. Results: During looking for visual disgusting stimulus, all participants reported unpleasantness, arousal and stress. In sLORETA analysis, the decrease of current density in theta wave was shown at left frontal superior gyrus (BA10) and middle gyrus (BA10, 11). This voxel cluster consists of a total of 11 voxels and the threshold of t value indicating statistically significant decreases in the current density (p<0.05) was -1.984. There were no differences between male and female in the degree of being disgusted by the stimuli. Conclusion: This finding may suggest that the activation of dorsolateral prefrontal cortex might be associated with regulating disgust emotion.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.5 no.1
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• pp.28-35
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• 1994

Research on biological aspects on adult depression has been subjected to more than 25 years of systematic research, while biologic investigations regarding childhood and adolescent depression are only now being initiated. Although no unifying, explanatory theory of the biologic etiology of childhood depression emerges from the results of studies reviewed above, the findings do support that biological factors may be involved in the genesis of childhood depression. The research reviewed in this paper suggests that age and pubertal factors have major effects in most biological markers of depression. Some of these markers, like sleep EEG and neuroendocrine markers should be broken down by decades during adult life span. Thus, although adult data are very valuable points of departure for biological research on child and adolescent depression, it is very hard to transfer the adult data to prepubertal children and adolescents, ignoring the biological changes that take place in growth and development, pubety and aging. A great deal of work in basic developmental neuroscience remains to be done. It will be crucial for further advances in this field to determine the normal patterns of neurotransmitter interaction in this age group and to study children at high risk for depression. It will be also crucial to use primate models of depressive illness in order to be able to answer the many queations that cannot be investigated in humans for ethical issues. Conclusively, much closer collaboration between developmental and neurobiological and behavioral studies in primates and in humans will be essential for further development.

• Sleep Medicine and Psychophysiology
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• v.11 no.1
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• pp.29-36
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• 2004

Objectives: Sound and light (SL) stimulation has been used as a method to induce some useful mental states in the fields of psychology and psychiatry. It is believed that sound and light entrainment device (SLED) has some specific effects through synchronization of EEG in patients who use it. Theta frequency is believed to stimulate deep relaxation and short term memory processing. This study was conducted to evaluate if 4-10 Hz SL stimulation can induce relaxation and improve short term memory function. Methods: Ten medical students with no medical or psychiatric problems participated in this study. Subjects were randomly divided into two groups. One group was applied with real SLED was applied to one group (R group) and pseudo SLED to the other group (P group). The two groups were exposed to SL stimulation with SLED 15 minutes a day for 5 days, and after two days rest the two groups were switched over. The Korean Wechsler Adult Intelligence Scale (K-WAIS), Academic Motivation Tests (AMT), Test Anxiety Scale (TAS), Korean Auditory Verbal Learning Test (K-AVLT), and digit span were used to evaluate short term memory. Spielberger's State-Trait anxiety inventory and heart rate variability (HRV) test were used to evaluate degree of relaxation. Results: Compared with S group, R group showed a significant improvement in K-AVLT and digit span after a single application of SL stimulation. But 5-day long application did not reveal any differences between the two groups. A significant change in HRV was observed in 5-day long application of SL stimulation after being switched over to other SLED. Conclusion: This pilot study suggests that 4-10 Hz SL stimulation has some positive influences on short term memory and relaxation.

• Clinical and Experimental Pediatrics
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• v.48 no.7
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• pp.753-759
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• 2005

Purpose : This study was performed to characterize clinical features of benign convulsions with gastroenteritis(CwG) in infants. Methods : We reviewed clinical features of 67 episodes in 64 patients with afebrile seizure accompanied gastroenteritis admitted to Dept. of Pediatrics Bundang CHA hospital from January 2001 to June 2004. Patients with meningitis, encephalitis/encephalopathy or apparent history of epilepsy were excluded. Results : There were 32 boys and 35 girls. The age of onset ranged from 1 to 42 months($18.5{\pm}6.1$ months). The number of children admitted to the hospital with acute gastroenteritis was 2,887 in the same period. The percentage of patients with CwG was 2.3. Seizure type was exclusively generalized tonic or tonic-clonic seizure. The average number of seizures during a single episode was 3.1 (range, 1-13). Two or more seizures occurred in 53(79.1%) of the 67 episodes. Antiepileptic drugs were administered for 42 episodes. Seizure did not cease after the administration of one kind of antiepileptic drug in 23 episodes(54.7%). The seizures were rather refractory to initial antiepileptic treatment. There were no abnormalities in serum biochemistry test including glucose and electrolytes. Cerebrospinal fluid was normal in all 54 episodes. Stool cultures were negative in 49 episodes. Rotavirus was positive in stools in 51(82.3%) of 62 episodes. Norovirus was positive in stools in 2 episodes and astrovirus in 1 of 18 episodes. CT and/or MRI were performed in 15 cases and demonstrated no neuroradiologic abnormalities. Of 73 Interictal EEG, initial 24 cases showed occasional spike or sharp wave discharges from the mid-line area during stage I-II sleep, which were apparently differentiated from vertex sharp transient or K-complexes. The mean follow-up period was 5.7 months(1-36 months). Three patients experienced a recurrence of CwG, but all patients exhibited normal psychomotor development at the last follow-up. Conclusion : Afebrile infantile convulsions with gastroenteritis are brief generalized seizure in cluster with normal laboratory findings and good prognosis. Therefore CwG is likely to be categorized as situation-related seizure of special syndrome. Recognition of this entity should lead to assurance of the parents and long-term anticonvulsant therapy is not usually warranted.