• Title/Summary/Keyword: Sleep Cycle

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Excessive Daytime Sleepiness Case Confounding with Thyrotoxicosis (과도한 주간 졸림과 탈력발작을 주소로 내원한 환자에서 발견된 갑상선 중독증)

  • Chung, Jae-Kyung;Kim, Eui-Joong
    • Sleep Medicine and Psychophysiology
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    • v.18 no.1
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    • pp.40-44
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    • 2011
  • Narcolepsy is a sleep disorder, which is characterized by excessive daytime sleepiness (EDS) that is typically associated with cataplexy, sleep fragmentation and other REM sleep-related phenomenon such as sleep paralysis and hypnagogic hallucination. Narcoleptic symptoms can be developed from various medical or neurological disorders. A 17-year-old male patient admitted for the evaluation of EDS which started three-month ago. He slept more than 18 hours a day with cataplexy and hypnagogic hallucination. He was obese with body mass index (BMI) of 30.4 kg/$m^2$. After admission he was newly diagnosed to the thyrotoxicosis. T3 391.2 ng/dL (60-181), free T4 4.38 ng/dL (0.89-1.76), TSH <0.01 ${\mu}IU$/mL (0.35-5.5) were measured. His pulse rate ranged 70-90 beats per minute and blood pressure ranged 150/100-120/70 mmHg. Polysomnography revealed many fragmentations in sleep with many positional changes (81 times/h). Sleep onset latency was 33.5 min, sleep efficiency was 47.9%, and REM latency from sleep onset was delayed to 153.6 min. REM sleep percent was increased to 27.1%. Periodic limb movement index was 13.4/h. In the multiple sleep latency test (MSLT), average sleep latency was 0.4 min and there were noted 3 SOREMPs (Sleep Onset REM sleep period) on 5 trials. We couldn't discriminate the obvious sleep-wake pattern in the actigraph and his HLA DQB1 $^*0602$ type was negative. His thyroid function improved following treatment with methimazole and propranolol. Vital sign maintained within normal range. Cataplexy was controlled with venlafaxine 75 mg. Subjective night sleep continuity and PLMS were improved with clonazepam 0.5 mg, but the EDS were partially improved with modafinil 200-400 mg. Thyrotoxicosis might give confounding role when we were evaluating the EDS, though sleep fragmentation was one of the major symptoms of narcolepsy, but enormous amount of it made us think of the influence of thyroid hormone. The loss of sleep-wake cycle, limited improvement of EDS to the stimulant treatmen, and the cataplexy not supported by HLA DQB1 $^*0602$ should be answered further. We still should rule out idiopathic hypersomnia and measuring CSF hypocretin level would be helpful.

The Effects of Total Sleep Deprivation on Anxiety, Mood, Sleepiness and Fatigue (전수면박탈이 정상인의 불안, 기분, 졸리움 및 피로도에 미치는 영향)

  • Lee, Heon-Jeong;Kim, Leen;Joe, Sook-Haeng;Suh, Kwang-Yoon
    • Sleep Medicine and Psychophysiology
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    • v.6 no.1
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    • pp.76-84
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    • 1999
  • Objectives: A number of studies have shown that sleep deprivation results in reduced vigilance and increased negative affects such as tension, depression and anger. However there are few studies about effects of sleep deprivation on anxiety. The purpose of this study was to investigate the effects of 40 hour sleep deprivation on state anxiety, affects, sleepiness and fatigue. The authors also intended to study the effect of trait-anxiety on these psychological variables after sleep deprivation. Methods: Twenty nine subjects(22 men, 7 women, $24.59{\pm}1.35$ years of age) participated in this study. Subjects had no past history of psychiatric disorders and physical illnesses, and had normal sleep-waking cycle without current sleep disturbances. All of the subjects completed sleep dairy for two weeks to exclude some who suffered from chronic sleep deprivation or sleep disturbances. Subjects were instructed to get a normal sleep as usual at night before the study. After awakening, subjects remained awake for 40 hours under continuous surveillance. They completed State-Trait Anxiety Inventory, Index of General Affect, Stanford Sleepiness Scale and Fatigue Questionnaire every three hours, therefore they completed the scales 14 times totally. Subjects were dictated not to take caffeine, alcohol, or any medications on the day of the study. Heavy exercises and naps were restricted too. Results: Sleep deprivation resulted in increased state anxiety, negative general affects, and increased sleepiness and fatigue(p<.001). Dividing into high trait-anxiety group and low trait-anxiety group, there was significant sleep deprivation x traitanxiety interaction effect on general affect(p<.05). But, there was no significant sleep deprivation x trait-anxiety interaction effect on state-anxiety, sleepiness and fatigue. During sleep deprivation, the highest ratings of scales on anxiety, negative affect, sleepiness and fatigue occurred between 4 : 00AM and 7 : 00AM. Conclusions: These results show that sleep deprivation results in increased anxiety, mood state disturbance and increment of sleepiness and fatigue. These findings also suggest that trait-anxiety is a factor that influences the degree of worsening in general affect caused by sleep deprivation. During sleep deprivation, the rating curves of anxiety, affect, sleepiness and fatigue show rhythmicity that may be related to circadian rhythm.

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Sleep Patterns of Middle and High School Students in Seoul (서울 거주 중.고등학교 학생의 학년별 수면 양상)

  • Song, Hyoung-Seok;Park, Young-Min;Nam, Min;Kim, Leen
    • Sleep Medicine and Psychophysiology
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    • v.7 no.1
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    • pp.51-59
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    • 2000
  • Objectives: It is been reported that sleep patterns change significantly during the adolescent years. In Korea, the sleep patterns of adolescents have not been investigated systematically. The authors performed preliminary study about sleep patterns of middle and high school students in Seoul before nationwide study. Methods: The authors selected one of middle and high schools located in typical middle class area in Seoul. The study was performed during the periods when examination or vacation did not affect the sleep cycle. Fifty to one hundred male and female students were selected from one school year each. One of investigators explained the purposes and methods of this study to the students and gave additional explanation to the teachers in charge. We designed a questionnaire for subjects to describe the nap time, bedtime, sleep latency, total sleep time, rise time and sleep efficiency, and the students recorded sleep logs for seven days including weekend. Eight hundred three students answered the questionnaires. Among them, we selected the subjects who recorded sleep logs at least three days and filled up the questionnaires completely. Finally, seven hundred seventy one subjects were included in this study. Weekend was defined as the time from Saturday morning to Sunday morning, and Sunday sleep patterns were treated separately. Results: Across the six school years, school-night bedtimes were delayed one hundred twenty four minutes and school-ight rise times were advanced by thirty five minutes. School-night total sleep times were decreased by one hundred fifty eight minutes, and weekend bedtimes were delayed by one hundred twenty five minutes. The students tended to oversleep on weekends, and the mean of weekend oversleep was ninety six minutes. But, bedtime in weekends was not delayed. Daytime sleep, sleep latency and sleep efficiency were not changed greatly across six school years. Total sleep time of female students was decreased significantly between third middle school year and first high school year, but time of male students was decreased between first and second high school year. Conclusion: It is supposed that sleep deficiency of middle and high school students in Seoul was due to delayed bedtimes and advanced rise times across the school years.

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Sleep/Wake Behavior of Shift Workers in the Iron and Steel Industry Using Wrist Actigraph (액티그라프를 이용한 철강업 교대근무자의 수면·각성 행태)

  • Moon, Se-Keun;Seo, Yoo-Jin;Matsumoto, Kazuya;Park, Young-Man;Ha, Tae-Young
    • Journal of Korean Institute of Industrial Engineers
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    • v.30 no.3
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    • pp.181-189
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    • 2004
  • The purpose of this study was to investigate the effects of sleep/wake behavior for shift workers in the iron and steel industry using wrist actigraph for 59 male workers on a continuous full-day three-team three-shift system of backward rotation including on-duty and off-duty periods. The wrist actigraph data were recorded for 15 days (l shift cycle) for each subject. The sleep length at home during night shift decreased significantly as compared to the morning or evening shifts. The night shift nap length increased significantly in all sections as compared to the morning or evening shifts. The nap length in the Steel Manufacturing Process and Rolling Process during night shift decreased significantly as compared to the Machine Maintenance Section, the Forwarding of Products Section, and the Field Management Section. However, the sleep length at home while off-duty period increased significantly. The percentage of nap length during night shift in the Rolling Process, Steel Manufacture Process, and the other three types of jobs was 16.0%, 20.4%, and about 50.0%, respectively. The nap length during night shift for the above 50 year olds increased significantly as compared to the below 50 year olds. Finally, we discussed the role of nap-taking during the burden on night shift workers and the increased difficulty in continuing their job.

Dysmenorrhea in High School Girls and Its influencing Factors (여고생의 월경곤란증 실태 및 그 영향 요인)

  • Kim, Song-Soon;Kim, Hyang-Soo
    • Journal of the Korea Convergence Society
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    • v.12 no.3
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    • pp.409-420
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    • 2021
  • The study is a descriptive research to determine high school girls' the status of dysmenorrhea and to look into influencing factors about how relationships between variables: sleep disturbance, stress, anxiety, dietary habit have an effect on dysmenorrhea. Our collected data consisted of 160 high school girls living in B metropolitan city. The study period lasted four weeks, going from Oct 12 to Nov 6, 2020. The resulting data was analyzed with SPSS/WIN 21.0 version to analyze. As a result of this study, The correlated factors of dysmenorrhea included sleep disturbance(r=.531, p<.001), stress(r=.349, p<.001), anxiety(r=.300, p=.003) and dietary habit(r=-.205, p=.041). The prevalent factors influencing dysmenorrhea are sleep disturbance, menstrual periods, menstrual cycles, and anxiety. Therefore, it will be needed to improve the quality of sleep, reduce anxiety, try to regulate menstrual periods and menstrual cycle in order to relieve high school girls' dysmenorrhea.

Low Power Neuromorphic Hardware Design and Implementation Based on Asynchronous Design Methodology (비동기 설계 방식기반의 저전력 뉴로모픽 하드웨어의 설계 및 구현)

  • Lee, Jin Kyung;Kim, Kyung Ki
    • Journal of Sensor Science and Technology
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    • v.29 no.1
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    • pp.68-73
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    • 2020
  • This paper proposes an asynchronous circuit design methodology using a new Single Gate Sleep Convention Logic (SG-SCL) with advantages such as low area overhead, low power consumption compared with the conventional null convention logic (NCL) methodologies. The delay-insensitive NCL asynchronous circuits consist of dual-rail structures using {DATA0, DATA1, NULL} encoding which carry a significant area overhead by comparison with single-rail structures. The area overhead can lead to high power consumption. In this paper, the proposed single gate SCL deploys a power gating structure for a new {DATA, SLEEP} encoding to achieve low area overhead and low power consumption maintaining high performance during DATA cycle. In this paper, the proposed methodology has been evaluated by a liquid state machine (LSM) for pattern and digit recognition using FPGA and a 0.18 ㎛ CMOS technology with a supply voltage of 1.8 V. the LSM is a neural network (NN) algorithm similar to a spiking neural network (SNN). The experimental results show that the proposed SG-SCL LSM reduced power consumption by 10% compared to the conventional LSM.

Design of a 25 mW 16 frame/s 10-bit Low Power CMOS Image Sensor for Mobile Appliances

  • Kim, Dae-Yun;Song, Min-Kyu
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.11 no.2
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    • pp.104-110
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    • 2011
  • A CMOS Image Sensor (CIS) mounted on mobile appliances requires low power consumption due to limitations of the battery life cycle. In order to reduce the power consumption of CIS, we propose novel power reduction techniques such as a data flip-flop circuit with leakage current elimination and a low power single slope analog-to-digital (A/D) converter with a sleep-mode comparator. Based on 0.13 ${\mu}m$ CMOS process, the chip satisfies QVGA resolution (320 ${\times}$ 240 pixels) that the cell pitch is 2.25 um and the structure is a 4-Tr active pixel sensor. From the experimental results, the performance of the CIS has a 10-b resolution, the operating speed of the CIS is 16 frame/s, and the power dissipation is 25 mW at a 3.3 V(analog)/1.8 V(digital) power supply. When we compare the proposed CIS with conventional ones, the power consumption was reduced by approximately 22% in the sleep mode, and 20% in the active mode.

A Traffic Aware Demand-Wakeup MAC(TADW-MAC) Protocol for Wireless Sensor Networks (무선 센서 네트워크에서 트래픽에 적응적인 Demand-Wakeup MAC 프로토콜)

  • Kim, Hye-Yun;Kim, Seong-Cheol
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.21 no.1
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    • pp.180-186
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    • 2017
  • In this paper we propose a traffic aware Demand Wakeup MAC(TADW-MAC) protocol, in which low data delay and high throughput can be achieved, for wireless sensor networks. With the TADW-MAC protocol, the problem of the DW-MAC protocol, which schedules only one packet to deliver during the Sleep period in a multi-hop transmission is resolved. DW-MAC is not adequate for the applications such as object tracking and fire detection, in which busty data should be transmitted in a limited time when an event occurs [6-8]. When an event occurs, duty cycle can be adjusted in the TADW-MAC protocol to get less energy consumption and low latency. The duty cycle mechanism has been widely used to save energy consumption of sensor node due to idle listening in wireless sensor networks. But additional delay in packet transmission may be increased in the mechanism. Our simulation results show that TADW-MAC outperforms RMAC and DW-MAC in terms of energy efficiency while achieving low latency.

The Energy Performance Analysis Between Synchronous and Asynchronous Duty Cycle based MAC Protocols in Wireless Sensor Networks (무선 센서네트워크 환경에서 Duty Cycle 기반 동기식 및 비동기식 MAC 프로토콜의 에너지 성능과 지연시간에 대한 상호 분석)

  • Lee, Jae-Ho;Eom, Doo-Seop
    • Journal of Information Technology Services
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    • v.10 no.3
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    • pp.237-250
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    • 2011
  • Recently, Wireless Sensor Networks (WSN) require energy performance and guaranteed delivery delay time, contrarily with previous MAC protocols that aim to high throughput mostly. In order to satisfy the new significant requirements, many MAC protocols of WSN employ and try to enhance the duty cycle mechanism which is energy efficient technique in MAC layer. This duty cycle mechanism is oriented by toggling the transceiver conditions composed of wakeup and sleep states. The synchronous MAC protocols perform the period synchronization process. Hence, these are energy efficient in periodic monitoring environment, but are inefficient in where an event is incurred rarely and infrequently. Otherwise, the performance of asynchronous MAC protocols are contrarily with synchronous protocols. In this paper, we design two models consisting Always-busy and Always-idle ti simplify the general network congestion conditions. Through these models, moreover, we analyze two types MAC protocols in terms of energy efficiency and delay performance by analytical results. Additionally, we also evaluate two MAC protocols with two gongestion models that we designed. By the analytical and simulated results, we provide the general and efficient decision method in which protocols are more appropriate in a certain WSN environment.