• Korean Journal of Agricultural Science
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• v.48 no.3
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• pp.567-574
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• 2021

In this study, we evaluated the wound healing rate and, inflammatory cells effects of by Abeliophyllum distichum Nakai (ADN) extract in mice. We also assessed the stability of the ADN extract upon exposure to sunlight. Treatments were as follows: 1) CON (only saline solution), T1 (CON + 0.0125% ADN extract), T2 (CON + 0.05% ADN extract), and T3 (CON + 0.5% ADN extract). A 4 mm punch was used in the central part of the dorsal area to separate it from the subcutaneous tissue, causing a full-thickness skin wound. An amount of 1 mL of each sample was sprayed onto the treatment section of the wound with a pipette every day from the day of wound creation, with proper application ensured using brush. In the stability test, the pH was measured at 1, 4, and 8 weeks after exposing the samples of each treatment section to sunlight considering, the higher concentrations of the ADN extract. The results of this study indicate that the effectiveness of the wound contraction rate in the mice to which the ADN extract was applied was low. Moreover, the stability of the sample containing a high concentration of the ADN extract could not be verified. In addition, no significant results were obtained in the inflammatory reaction assessment. Therefore, additional research focusing on wound contraction, stability, and inflammatory cell outcomes of the ADN extract is needed.

• Journal of the Korean Society of Industry Convergence
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• v.23 no.4_2
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• pp.701-708
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• 2020

In this paper, we analyzed the optical properties of the LED module for dental care, which has the effect of promoting cell regeneration and scar treatment. The LED module is a U-shaped module suitable for the shape of teeth. It is manufactured with an LED module (632 nm) and an LED module (632 nm + 870 nm), analyzes the results of optical properties, sets the irradiation distance, irradiation time, and is effective in healing skin wounds. Evaluation was conducted. It was tested in 6 test groups according to the light irradiation conditions, and light was irradiated to the scar site every other day for 7 days, 1 day and 3 days. As a result, it was confirmed that the effect of scar treatment was the highest when the combined wavelength of 632 nm + 870 nm was irradiated in pulse mode than when the single wavelength was irradiated and the composite wavelength was continuously irradiated. In group C group irradiated with PW Mode: pulse mode (period 36 ms, pulse width 35 ms) using a composite wavelength with LED module (632 nm + 870 nm) than group A without light irradiation, the length of scar reduction was 19 %, the area of the scar was further reduced by 10%, and it was confirmed that it is effective in treating scars in the wound area.